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Clinical features of alcoholic hepatitis in latinos and caucasians: A single center experience

World Journal of Gastroenterology 2017年第40期23卷 7274-7282页

作者： rogelio pinon-gutierrez Blythe Durbin-Johnson Charles H Halsted Valentina Medici Division of Gastroenterology and Hepatology Department of Internal Medicine University of California Davis Division of Biostatistics University of California Davis Department of Public Health Sciences

AIM To study differences of presentation, management, and prognosis of alcoholic hepatitis in Latinos compared to Caucasians. METHODS We retrospectively screened 876 charts of Caucasian and Latino patients who were evaluated at University of California Davis Medical Center between 1/1/2002-12/31/2014 with the diagnosis of alcoholic liver disease. We identified and collected data on 137 Caucasians and 64 Latinos who met criteria for alcoholic hepatitis, including chronic history of heavy alcohol use, at least one episode of jaundice with bilirubin ≥ 3.0 orcoagulopathy, new onset of liver decompensation or acute liver decompensation in known cirrhosis within 12 wk of last drink. RESULTS The mean age at presentation of alcoholic hepatitis was not significantly different between Latinos and Caucasians. There was significant lower rate of overall substance abuse in Caucasians compared to Latinos and Latinos had a higher rate of methamphetamine abuse(12.5% vs 0.7%) compared to Caucasians. Latinos had a higher mean number of hospitalizations(5.3 ± 5.6 vs 2.7 ± 2.7, P = 0.001) and mean Emergency Department visits(9.5 ± 10.8 vs 4.5 ± 4.1, P = 0.017) for alcohol related issues and complications compared to Caucasians. There was significantly higher rate of complications of portal hypertension including gastrointestinal bleeding(79.7% vs 45.3%, P < 0.001), spontaneous bacterial peritonitis(26.6% vs 9.5%, P = 0.003), and encephalopathy(81.2% vs 55.5%, P = 0.001) in Latinos compared to *** Latinos have significant higher rates of utilization of acute care services for manifestations alcoholic hepatitis and complications suggesting poor access to outpatient care.

关键词： Alcoholic hepatitis Latino Hispanic Caucasian Alcoholic liver disease

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Modeling Study of the Evolution of the Climate Crisis over Time

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Open Journal of Applied Sciences 2024年第2期14卷 330-342页

作者： Victor rogelio Tirado Picado Directorate of Research and University Extension American University (UAM) Managua Nicaragua

The research proposal has the following scope. In relation to the general objective, the aim is to model the evolution of the climate crisis over time taking as variables global warming, greenhouse gases, atmospheric temperature and ocean temperature, as well as the continuity of the natural phenomena in terms of their measurement, temporality and projection. To achieve the above, the description of the following specific objectives is proposed: - Identify the variables corresponding to the climate crisis, their relationship and correlation between them;- Develop projection models with mathematical and statistical arrangements to project them in a given time and, in this way, - Propose mitigation measures for different unfavorable scenarios. The main variables that are currently directly linked to Climate Change are: CO2, the atmospheric index, precipitation, temperature and wind speed. The correlation that exists between climatic elements is very high, both in historical behavior and projected behavior for 2035, their correlation is estimated at 0.90, 0.95, 0.93 and 91 respectively. The mathematical models used to manipulate the historical and projected analysis of the variables studied: are the normal arrangements, this ensures that the values can be used on a common scale;Then there is the analysis of the historical variables using the linear trend, and finally there is the analysis of the variables projected to the year 2035 using the polynomial trend. In both situations, the direct relationship of greenhouse gases, mainly CO2, is directly related to the variations of the variables over time, which is a very worrying result because we can no longer talk about climate change, but rather about CLIMATE CRISIS. To a large extent, a change in the paradigm of exploitation of the resources of our mother earth is required. Alert in an SOS manner to the great powers, which make reasonable use of technology, for this attenuation measures are proposed

关键词： Climate Crisis Model Climatic Factors Evolution Temperature

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Organ Abscission in Plants: With Special Emphasis on Bell Pepper

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Phyton-International Journal of Experimental Botany 2024年第7期93卷 1467-1484页

作者： Ramiro Reyes-Castro Héctor G.Núñez-Palenius Juan I.Valiente-Banuet María E.Sosa-Morales Blanca E.Orosco-Alcalá Rafael Guzmán-Mendoza Graciela M.L.Ruiz-Aguilar rogelio Costilla-Salazar Life Sciences Division Universidad de GuanajuatoIrapuato36500México School of Engineering and Sciences Tecnologico de MonterreyQuerétaro76130México

Bell pepper(Capsicum annuum L.),along with potato and tomato,is one of the three most cultivated vegetables in the *** pepper is worldwide accepted due to its characteristics of color,smell,ﬂavor,and *** pepper is also considered a nutritious food due to its vitamin and antioxidant *** Mexico,bell pepper production has a high value because it is grown for the international markets,particularly the United States of ***,the abscission ofﬂowers and fruits is a factor that limits the yield,hinders the planning of activities,and causes a variation in the prices of *** to the importance of this process,in this work we did a bibliometric analysis and literature review of scientiﬁc advances for the understanding of the abscission pro-cess in plants,and in particular for the bell ***,we introduce new perspectives that would help direct future research about organ abscission in ***,the lack of research that would further clarify abscis-sion process in the bell pepper plant is discussed.

关键词： Capsicum annuum abscission zone plant growth regulators environmental factors

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Design and Implementation of a Rehabilitation Upper-limb Exoskeleton Robot Controlled by Cognitive and Physical Interfaces

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Journal of Bionic Engineering 2022年第5期19卷 1374-1391页

作者： Arturo Gonzalez‑Mendoza Ivett Quinones‑Uriostegui Sergio Salazar‑Cruz Alberto‑Isaac Perez‑Sanpablo Ricardo Lopez‑gutierrez rogelio Lozano LAFMIA UMI Center for Research and AdvancedStudies of National Polytechnic InstituteAv.Instituto Politecnico Nacional No.250807360 Mexico CityMexico Motion Analysis Lab National Institute of Rehabilitation Luis Guillermo Ibarra IbarraCalz.Mexico Xochimilco No.28914389 Mexico CityMexico CONACYT-CINVESTAV Av.Instituto Politecnico Nacional 250807360 Mexico CityMexico UTC-CNRS UMR Sorbonne UniversitesUTC-CNRS UMR7253 HeudiasycCompiegneFrance

This paper presents an upper limb exoskeleton that allows cognitive(through electromyography signals)and physical user interaction(through load cells sensors)for passive and active exercises that can activate neuroplasticity in the rehabilitation process of people who suffer from a neurological *** the exoskeleton to be easily accepted by patients who suffer from a neurological injury,we used the ISO9241-210:2010 as a methodology design *** the first steps of the design process,design requirements were collected from previous usability tests and ***,as a second step,a technological solution is proposed,and as a third step,the system was evaluated through performance and user *** part of the technological solution and to allow patient participation during the rehabilitation process,we have proposed a hybrid admittance control whose input is load cell or electromyography *** hybrid admittance control is intended for active therapy exercises,is easily implemented,and does not need musculoskeletal modeling to ***,electromyography signals classification models and features were evaluated to identify the best settings for the cognitive human–robot interaction.

关键词： Human Robot interaction Hybrid admittance control Surface electromyography Upper-limb exoskeletal robot

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Comparison of Control Techniques in a Weight Lifting Exoskeleton

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Journal of Bionic Engineering 2019年第4期16卷 663-673页

作者： Irving Rosales-Diaz Jesus Ricardo Lopez-gutierrez Angel Eduardo Zamora Suarez Sergio Rosario Salazar Antonio Osorio-Cordero Hipolito Aguilar-Sierra rogelio Lozano CINVESTAV Av.Institute Politecnico Nacional 2508Col.San Pedro Zacatenco07360Mexico CityMexico CONACYT-CINVESTAV Av.Institute Politecnico Nacional 2508Col.San Pedro Zacatenco07360Mexico CityMexico Polytechnic University of Tulancingo St.Ingenierias 100Col.Huapalcalco43629TulancingoHidalgoMexico Centre de Recherches de Royalieu UTC-HEUDIASyCCompiegne60205France

The back pain is the most common injury in human activities where heavy objects must be lifted or must be suspended for a long time.A weight lifting exoskeleton also known as force augmentation exoskeleton is designed to reduce the strain on the back and the limbs and reduce the risk to suffer *** the other hand,different kinds of controllers have been implemented to achieve whit this goal,for example,a conventional PD Control,PD Control with Gravity Compensation,PD Control with Adaptive Desired Gravity Compensation and PD Control with Robust *** paper aims to evaluate and compare the performance from the previously cited controllers used to reduce the strain in the back,through the implementation of each controller in a three Degrees Of Freedom(DOF)exoskeleton powered by pneumatic muscle actuators;some numerical simulations as well as experimental trials have been conducted and three different performance indices were used in order to determine the effectiveness of each one with respect to the simple PD controller when the mass to be lifted is unknown.

关键词： augmenting force device exoskeleton robot pneumatic artificial muscles adaptive control robust control

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Green Synthesis of Silver Nanoparticles Using Annona diversifolia Leaf Extract and Their Antimicrobial Application

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Journal of Renewable Materials 2020年第9期8卷 1129-1137页

作者： rogelio Solorzano-Toala Daniel Gonzalez-Mendoza Benjamin Valdez-Salas Vianey Mendez-Trujillo Federico gutierrez-Miceli Ernesto Beltran-Partida Olivia Tzintzun-Camacho Tecnológico Nacional de México-Campus Tuxtla Gutiérrez Tuxtla Gutiérrez03940México Instituto de Ciencias Agrícolas de la Universidad Autónoma de Baja California Mexicali21705México Instituto de Ingeniería de la Universidad Autónoma de Baja California Mexicali21100México Facultad de Medicina de la Universidad Autónoma de Baja California Mexicali21100México

The aim of this study was the synthesis of silver nanoparticle using Annona diversifolia *** silver nanoparticles obtained were analyzed by spectroscopic methods and dynamic light scattering *** inhibition of AgNPs was evaluated against Bacillus cereus,Klebsiella pneumoniae and Enterobacter *** results showed that AgNPs have high values at 3 keV and particle size between 45 to 58 nm with a homogenous *** AgNPs showed growth inhibition against Klebsiella pneumoniae and Enterobacter *** studies are needed to confirm the potential antimicrobial of different AgNP from *** in Gram negative and Gram positive bacteria.

关键词： Green chemistry AgNPs plants antimicrobial biotechnology

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Influence of CFH,HTRA1 and ARMS2 polymorphisms in the response to intravitreal ranibizumab treatment for wet age-related macular degeneration in a Spanish population

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International Journal of Ophthalmology(English edition) 2016年第9期9卷 1304-1309页

作者： Fernando Cruz-Gonzalez Lucia Cabrillo-Estevez Vanesa Rivero-gutierrez Ana Sanchez-Jara Lourdes De Juan-Marcos rogelio Gonzalez-Sarmiento Department of Ophthalmology Hospital Universitario Salamanca

AIM：To determine whether gene polymorphisms of the major genetic risk loci for age-related macular degeneration（AMD）：ARMS2（rs10490923）,the complement factor H（CFH）（rs1410996） and HTRA1（rs11200638） influence the response to a treatment regimen with ranibizumab for exudative ***：This study included 100 patients（100 eyes）with exudative *** underwent a treatment with ranibizumab injections monthly during three *** were made when the best corrected visual acuity（BCVA） decrease five letters（ETDRS） or central subfield retinal thickness gained 100 pm in optical coherence tomography ***（rs10490923,rs1410996 and rs11200638） were analyzed using TaqMan probes or polymerase chain reaction-restricted fragment length polymorphisms ***：There were no statistically significant differences in allelic distribution of CFH（rs1410996）,ARMS2（rs10490923） and HTRA1（rs11200638）polymorphisms regarding to response to ranibizumab ***：Ranibizumab treatment response is not related to CFH（rs1410996）,ARMS2（rs10490923） and HTRA1（rs11200638） poymorphisms.

关键词： age-related macular degeneration polymorphisms ARMS2 HTRA1 complement factor H ranibizumab

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Adaptive Control for Passive Kinesiotherapy ELLTIO

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Journal of Bionic Engineering 2014年第4期11卷 581-588页

作者： Ricardo López Hipólito Aguilar Sergio Salazar rogelio Lozano Laboratory UMI LAFMIA 3175 CINVESTAV-CNRS Móxico D. F. CNRS Research Director Universitb de Technologie de Compiègne 60200 Compiègne France

Exoskeletons are mechatronic devices used to increase human muscle strength and resistance. In the last decade these devices have become a very useful tool to assist active kinesiotherapy. This paper presents the design of exoskeleton focused on the rehabilitation of ankle and knee for the right leg. The construction of prototype like Exoskeleton for Lower Limb Training with Instrumented Orthoses （ELLTIO） using Series Elastic Actuator （SEA） to reduce the effort in the human joints, and a control law to perform a rehabilitation routine using an adaptive control scheme were first implemented in simulation to verify the control strategy and make a real rehabilitation test. The adaptive control law is proposed with the intention that the exoskeleton can adapt to user parameters at the time when performing the exercise. The results show the parameters estimation and tracking trajectory for the exoskeleton were proposed, and this trajectory could be a routine rehabilitation proposed by the therapist.

关键词： exoskeleton parametric identification rehabilitation robotics adaptive control.

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Tolerance of Chrysantemum maximum to heavy metals:The potential for its use in the revegetation of tailings heaps

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Journal of Environmental Sciences 2013年第2期25卷 367-375页

作者： Ma.del Carmen A.Gonzlez-Chvez rogelio Carrillo-Gonzlez Colegio de Postgraduados Programa de EdafologíaCarr.Mxico-Texcocokm 36.5MontecilloTexcoco estado de Mxico 56230Mxico

To find if ornamental plants are applicable to the remediation of metal-polluted areas, the tolerance of chrysanthemum plants （Chysanthemum maximum） var. Shasta to different metals under hydroponic conditions was studied. Their responses as influenced by the mycorrhizal fungus Glomus mosseae （Nicol. ＆ Gerd.） Gerdemann ＆ Trappe BEG25 on substrates containing mine residues were also investigated. Our results showed that chrysanthemum is a metal-tolerant plant under hydroponic conditions, plants behaving as Pb-excluders, whereas Cd, Cu and Ni were accumulated in roots. Low accumulation in flowers was observed for Cd and Cu but it was concentration-dependent. Ni and Pb were not translocated to flowers. Shoot biomass was not significantly affected by the different rates of mine residue addition for both mycorrhizal and non-mycorrhizal plants. Mycorrhizal plants accumulated less Pb and Cu in both shoots and roots than non-mycorrhizal plants. Chysanthemum could be a prospective plant for revegetation of tailings and the use of inoculation may decrease plant metal accumulation in polluted soils.

关键词： mine residues ornamental plants phytostabilization urban remediation

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Determining the need for a thoracoscopic approach to treat a giant hiatal hernia when abdominal access is poor

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World Journal of Gastrointestinal Surgery 2023年第12期15卷 2739-2746页

作者： Francisco Javier Pérez Lara rogelio Zubizarreta Jimenez Tatiana Prieto-Puga Arjona Pilar gutierrez Delgado Juan Manuel Hernández Carmona Jose Manuel Hernández Gonzalez Maria Pitarch Martinez Department of Surgery Hopital de AntequeraAntequera 29200Spain DOXA MicrofluidicsRincon de la Victoria 29730Spain Department of Surgery HRU Carlos HayaUnidad Cirugia Hepatobiliopancreat&TrasplantesMalaga 29200Spain

BACKGROUND Giant hernias present a significant challenge for digestive *** approach taken(laparoscopic vs thoracoscopic)depends largely on the preferences and skills of each surgeon,although in most cases today the laparoscopic approach is *** To determine whether patients presenting inadequate laparoscopic access to the intrathoracic hernial sac obtain poorer postoperative results than those with no such problem,in order to assess the need for a thoracoscopic *** For the retrospective series of patients treated in our hospital for hiatal hernia(n=112),we calculated the laparoscopic field of view and the working area accessible to surgical instruments,by means of preoperative imaging tests,to assess the likely outcome for cases inaccessible to *** Patients with giant hiatal hernias for whom a preoperative calculation suggested that the laparoscopic route would not access all areas of the intrathoracic sac presented higher rates of perioperative complications and recurrence during follow-up than those for whom laparoscopy was *** difference was statistically ***,the insertion of mesh did not improve results for the non-accessible *** For patients with giant hiatal hernias,it is essential to conduct a preoperative evaluation of the angle of vision and the working area for *** parts of the intrathoracic sac are inaccessible laparoscopically,the thoracoscopic approach should be considered.

关键词： Hiatal hernia Abdominal surgery Laparoscopy Thoracoscopy surgery

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