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Applied Mathematics and Mechanics(English Edition) 2023年第4期44卷 653-668页

作者： b.J.GIREESHA M.l.KEERTHI Department of PG Studies and Research in Mathematics Kuvempu UniversityShankaraghatta 577451India

A moving trapezoidal profiled convective-radiative porous longitudinal fin wetted in a single-phase fluid is considered in the current *** periodic variation in the fin base temperature is taken into account along with the temperature sensitive thermal conductivity and convective heat transfer *** modeled problem,which is resolved into a non-linear partial differential equation(PDE),is made dimensionless and solved by employing the finite difference method(FDM).The results are displayed through graphs and *** effects of amplitude,frequency of oscillation,wet nature,Peclet number,and other relevant quantities on the distribution of temperature through the fin length and with the dimensionless time are *** is deciphered that the periodic heat transfer gives rise to the wavy nature of the fin thermal profile against *** analysis is beneficial in the design of fin structures for applications like solar collectors,space/airborne applications,and refrigeration industries.

关键词： convection fully wet porous fin trapezoidal profile moving fin unsteady periodic thermal condition

Dynamic Control of Multiple Optical Patterns of Cholesteric liquid Crystal Microdroplets by light-Driven Molecular Motors

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CCS Chemistry 2024年第2期6卷 427-438页

作者： Jiaqin li Shuting Xie Jiahui Meng Yuying liu Qi Zhan Yang Zhang lingling Shui Guofu Zhou ben l.Feringa Jiawen Chen SCNU-UG International Joint laboratory of Molecular Science and Displays National Center for International Research on Green OptoelectronicsSouth China Normal UniversityGuangzhou 510006 Joint laboratory of Optofluidic Technology and Systems Guangdong Provincial Key Laboratory of Nanophotonic Functional Materials and DevicesSchool of Information and Optoelectronic Science and EngineeringSouth China Normal UniversityGuangzhou 510006 Stratingh Institute for Chemistry University of Groningen9747AG Groningen

The key to high-level encryption and anti-counterfeiting techniques is the storage of multiple levels of distinct information that can be individually and precisely addressed by certain *** continues to be a formidable challenge as the concealed images or codes must be read with fast response and high resolution without cross-talk to the first layer of ***,we report a non-fluorescencebased strategy to establish responsive encryption lab.l. taking advantage of solely tuning multiple optical patterns of cholesteric liquid crystal(ClC)microdroplets doped with light-driven molecular *** photo-triggered unidirectional rotation of the motor induced not only changes in the helical twist power value but the opposite helical orientation of the superstructure in ClCs as well,resulting in changes in both the structural color and the selective reflection of circularly polar *** designed lab.l.,which featured highly selective addressab.l.ty of dual-level distinct information,good reversib.l.ty,and viewing angle-independence,were applied to build devices for daily practical use,demonstrating great potential in anti-counterfeiting technology and provide a versatile platform for enhanced data protection and encryption of authentic information.

关键词： molecular motor chirality amplification cholesteric liquid crystal anti-counterfeiting label data encryption

Effect of fosfomycin,Cynara scolymus extract,deoxynivalenol and their combinations on intestinal health of weaned piglets

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Animal Nutrition 2019年第4期5卷 386-395页

作者： Guadalupe Martinez Susana N.Dieguez Maria b.Fernandez Paggi Maria b.Riccio Denisa S.Perez Gaudio Edgardo rodriguez Fabian A.Amanto Maria O.Tapia Alejandro l.Soraci Area Toxicología Departamento de FisiopatologíaFacultad de Ciencias VeterinariasUniversidad Nacional del Centro de la Provincia de Buenos AiresTandilB7000Buenos AiresArgentina Centro de Investigación Veterinaria de Tandil(CIVETAN) UNCPBA-CICPBA-CONICETFacultad de Ciencias VeterinariasCampus UniversitarioTandilB7000Buenos AiresArgentina Consejo Nacional de Investigaciónes Científicas-CONICET Buenos AiresC1425FQBArgentina Comisión de Investigaciónes Científicas de la Provincia de buenos Aires(CIC-PbA) La PlataB1900Buenos AiresArgentina Area Producción Porcina Departamento de Producción AnimalFacultad de Ciencias VeterinariasUniversidad Nacional del Centro de La Provincia de Buenos AiresTandilB7000Buenos AiresArgentina Area Estadística Sanidad Animal y Medicina PreventivaFacultad de Ciencias VeterinariasUniversiclacl Nacional del Centro de la Provincia de Buenos AiresTandilB7000Buenos AiresArgentina

Weaning is a challenging stage of pig *** undergo environmental,social and dietary changes leading to weaning stress *** order to compensate for the detrimental effects of weaning stress,antibiotics and natural extracts are used as feed additives,sometimes without fully understanding the interactions between them or even with low concentrations of mycotoxins that are frequently present in *** aim of this study was to evaluate the effect of fosfomycin(FOS),Cynara scolymus extract(CSE),deoxynivalenol(DON) and their combined administration on intestinal health of weaned *** experiment was designed as a 2×2×2 factorial arrangement with 3 factors(FOS,CSE and DON treatments),2 levels each(presence and absence) and 3 *** piglets(n=24)were randomly divided in groups to receive the different treatments,namely DON administered in diet(50 μg/kg bW),FOS administered into the drinking water(30 mg/kg bW),CSE administered in diet(15 mg/kg bW) and all their *** 15 d,the animals were euthanized and gastrointestinal tract samples were immediately taken to evaluate gastrointestinal pH,Enterobacteriaceae to lactic acid bacteria(E:l) ratio,volatile fatty acid(VFA) concentrations,disaccharidase(lactase,sucrase and maltase)activity,histology(intestinal absorptive area [IAA] and goblet cells count) and mucus ab.l.ty to adhere pathogenic Escherichia *** our results,FOS and CSE treatments,individually or combined,produced a lower E:l ratio,an enhanced production of butyrate,increased disaccharidase activity(particularly maltase),and a greater IAA and goblet cells count along with an increase in pathogenic bacteria adherence to intestinal *** did not show interactions with the other factors and its administration produced decreases on VFA,disaccharidase activity and goblet cells *** conclusion,weaning piglets receiving diets containing FOS,CSE or both exhibited evident beneficial intestinal effects compared

关键词： Fosfomycin Cynara scolymus extract Deoxynivalenol Intestinal health Weaned piglets

全球环境变化中的土地使用与地面覆盖:供研讨的几点思考

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国际社会科学杂志（中文版） 1992年第4期9卷 81-91页

作者： b.l.特纳第二威廉·b·迈耶高銛乔治·珀金斯·马什研究所

自然与社会的关系对于全球环境变化研究的重要性,已经日益得到承认,人们对这个变化中的"人的因素",大书特书。社会科学的一些部分,有着研究社会与自然环境相互作用的长期传统,而"全球环境变化中的人的因素"的明显意义有希望促使这些部... 详细信息

自然与社会的关系对于全球环境变化研究的重要性,已经日益得到承认,人们对这个变化中的"人的因素",大书特书。社会科学的一些部分,有着研究社会与自然环境相互作用的长期传统,而"全球环境变化中的人的因素"的明显意义有希望促使这些部分分工合作,共同进行探讨。

关键词：土地使用环境变化地面覆盖社会与自然土地状况全球变化工业用地人口增长人的因素机会成本

Exploring the effects of dietary inulin in rainbow trout fed a high‑starch,100%plant‑based diet

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Journal of Animal Science and biotechnology 2024年第2期15卷 713-732页

作者： Raphaël Defaix Jep lokesh laura Frohn Mickael le bechec Thierry Pigot Vincent Veron Anne Surget Sandra biasutti Frederic Terrier Sandrine Skiba-Cassy Jerome Roy Stephane Panserat Karine Ricaud Universite de Pau Et Des Pays de l’Adour E2S UPPAINRAENUMEASaint‑Pee‑Sur‑NivelleFrance Universite de Pau Et Des Pays de l’Adour E2S UPPACNRSIMT Mines AlesIPREMPauFrance Universite de Pau Et Des Pays de l’Adour E2S UPPAIUT des Pays de l’AdourDepartement Genie BiologiqueMont de MarsanFrance.

background High dietary carbohydrates can spare protein in rainbow trout(Oncorhynchus mykiss)but may affect growth and ***,a prebiotic,could have nutritional and metab.l.c effects,along with anti-inflammatory properties in teleosts,improving growth and *** tested this hypothesis in rainbow trout by feeding them a 100%plant-based diet,which is a viable alternative to fishmeal and fish oil in aquaculture *** a two-factor design,we examined the impact of inulin(2%)as well as the variation in the carbohydrates(CHO)/plant protein ratio on rainbow *** assessed the influence of these factors on zootechnical parameters,plasma metab.l.tes,gut microbiota,production of short-chain fatty acids and lactic acid,as well as the expression of free-fatty acid receptor genes in the mid-intestine,intermediary liver metab.l.sm,and immune markers in a 12-week feeding *** The use of 2%inulin did not significantly change the fish intestinal microbiota,but interestingly,the high CHO/protein ratio group showed a change in intestinal microbiota and in particular the beta diversity,with 21 bacterial genera affected,including Ralstonia,bacillus,and 11 lactic-acid producing *** were higher levels of butyric,and valeric acid in groups fed with high CHO/protein diet but not with *** high CHO/protein group showed a decrease in the expression of pro-inflammatory cytokines(il1b,il8,and tnfa)in liver and a lower expression of the genes coding for tight-junction proteins in mid-intestine(tjp1a and tjp3).However,the 2%inulin did not modify the expression of plasma immune ***,inulin induced a negative effect on rainbow trout growth performance irrespective of the dietary *** With a 100%plant-based diet,inclusion of high levels of carbohydrates could be a promising way for fish nutrition in aquaculture through a protein sparing effect whereas the supplementation of 2%inulin does not appear to improve the use of CHO wh

关键词： Aquaculture Fish nutrition Gut microbiota Immune markers Intermediary metab.l.sm Inulin Prebiotic Rainbow trout Short-chain fatty acids

Coulomb-assisted nonlocal electron transport between two pairs of Majorana bound states in a superconducting island

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Chinese Physics b 2024年第5期33卷 275-279页

作者：王浩迪任俊潼吕海峰柯莎莎 School of Physics University of Electronic Science and Technology of ChinaChengdu 610054China

We investigate the nonlocal transport modulated by Coulomb interactions in devices comprising two interacting Majorana wires,where both nanowires are in proximity to a mesoscopic superconducting(SC)*** Majorana bound state(MbS)is coupled to one lead via a quantum dot with resonant *** this device,the nonlocal correlations can be induced in the absence of Majorana energy *** find that the negative differential conductance and giant current noise cross correlation could be induced,due to the interplay between nonlocality of MbSs and dynamical Coulomb blockade *** feature may provide a signature for the existence of the MbSs.

关键词： Majorana bound states superconducting island current cross correlation

High resolution colonoscopy in a bowel cancer screening program improves polyp detection

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World Journal of Gastroenterology 2011年第38期17卷 4308-4313页

作者： Matthew R banks Rehan Haidry M Adil butt lisa Whitley Judith Stein louise langmead Stuart l bloom Austin O' bichere Sara McCartney Kalpesh basherdas Manuel rodriguez-Justo laurence b.l.vat Department of Gastrointestinal Services University College London Hospitals NHS Foundation Trust Department of Histopathology University College London Hospitals NHS Foundation Trust

AIM： To compare high resolution colonoscopy （Olympus lucera） with a megapixel high resolution system （Pentax Hiline） as an in-service evaluation. METHODS： Polyp detection rates and measures of performance were collected for 269 colonoscopy procedures. Five colonoscopists conducted the study over a three month period, as part of the United Kingdom bowel cancer screening program. RESUlTS：There were no differences in procedure duration （x^2 p = 0.98）, caecal intubation rates （x^2 P = 0.67）, or depth of sedation （x^2 P = 0.64）. Mild discomfort was more common in the Pentax group （x^2 p = 0.036）. Adenoma detection rate was significantly higher in the Pentax group （x^2 test for trend P = 0.01）. Most of the extra polyps detected were flat or sessile adenomas. CONClUSION： Megapixel definition colonoscopes improve adenoma detection without compromising other measures of endoscope performance. Increased polyp detection rates may improve future outcomes in bowel cancer screening programs.

关键词： High resolution colonoscopy bowel cancerscreening Polyp detection

Combined Effects of Different Overload Ratios and Nitriding Process on Fatigue Crack Growth of AISI 4140 Steel

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Journal of Iron and Steel Research International 2014年第8期21卷 797-803页

作者： A.b.Sengül A.elik Department of Mechanical Engineering anakkale Onsekiz Mart University Department of Mechanical Engineering Ataturk University

The combined effects of different overload ratios（OlRs）and nitriding process on fatigue crack growth（FCG）were *** compact tension specimens made of AISI 4140 steel were subjected to the plasma nitrification process using agas mixture of 50% N2 and 50% H2 at 500℃for *** properties of the samples were studied by scanning electron microscopy,optical microscopy,microhardness testing and digital *** nitriding slowed down FCG,but the crack growth retardation caused by the overload was reduced when the OlR was 2.0and *** did not take effect when the OlR was 1.5and 3.0.

关键词： fatigue crack growth plasma nitriding overload ratio retardation digital image correlation

Immunotherapy and therapeutic vaccines in prostate cancer： an update on current strategies and clinical implications

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Asian Journal of Andrology 2014年第3期16卷 364-371页

作者： b Harpreet Singh James l Gulley Medical Oncology branch Center for Cancer Research National Cancer Institute National Institutes of Health 10 Center Drive Bethesda Maryland USA

In recent years, immunotherapy has emerged as a viable and attractive strategy for the treatment of prostate cancer. While there are multiple ways to target the immune system, therapeutic cancer vaccines and immune checkpoint inhibitors have been most successful in late-stage clinical trials. The landmark Food and Drug Administration approval of sipuleuceI-T for asymptomatic or minimally symptomatic metastatic prostate cancer set the stage for ongoing phase III trials with the cancer vaccine PSA-TRICOM and the immune checkpoint inhibitor ipilimumab. A common feature of these immune-based therapies is the appearance of improved overall survival without short-term changes in disease progression. This class effect appears to be due to modulation of tumor growth rate kinetics, in which the activated immune system exerts constant immunologic pressure that slows net tumor growth. Emerging data suggest that the ideal population for clinical trials of cancer vaccines is patients with lower tumor volume and less aggressive disease. Combination strategies that combine immunotherapy with standard therapies have been shown to augment both immune response and clinical benefit.

关键词： androgen deprivation immunotherapy prostate cancer therapeutic cancer vaccines

Silk-based nerve guidance conduits with macroscopic holes modulate the vascularization of regenerating rat sciatic nerve

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Neural Regeneration Research 2025年第6期20卷 1789-1800页

作者： Carina Hromada Patrick Heimel Markus Kerbl lászlóGál Sylvia Nürnberger barbara Schaedl James Ferguson Nicole Swiadek Xavier Monforte Johannes C.Heinzel Antal Nógrádi Andreas H.Teuschl-Woller David Hercher Department life Science Engineering University of Applied Sciences Technikum WienViennaAustria Austrian Cluster for Tissue Regeneration ViennaAustria ludwig b.l.zmann Institute for Traumatology The Research Center in Cooperation with AUVAViennaAustria University Clinic of Dentistry Medical University of ViennaViennaAustria Department of Plastic Reconstructive and Aesthetic SurgeryLandesklinikum Wiener Neustadt2700 Wiener NeustadtAustria Department of Anatomy Histology and EmbryologyAlbert Szent-Györgyi Medical SchoolUniversity of SzegedSzegedHungary Medical University of Vienna Department of Orthopedics and Trauma SurgeryDevision of Trauma SurgeryViennaAustria Department of Hand- PlasticReconstructive and Burn SurgeryBG Unfallklinik TuebingenUniversity of TuebingenTuebingenGermany

Peripheral nerve injuries induce a severe motor and sensory deficit. Since the availab.l.ty of autologous nerve transplants for nerve repair is very limited, alternative treatment strategies are sought, including the use of tub.l.r nerve guidance conduits(tNGCs). However, the use of tNGCs results in poor functional recovery and central necrosis of the regenerating tissue, which limits their application to short nerve lesion defects(typically shorter than 3 cm). Given the importance of vascularization in nerve regeneration, we hypothesized that enabling the growth of blood vessels from the surrounding tissue into the regenerating nerve within the tNGC would help eliminate necrotic processes and lead to improved regeneration. In this study, we reported the application of macroscopic holes into the tub.l.r walls of silk-based tNGCs and compared the various features of these improved silk^(+) tNGCs with the tubes without holes(silk^(–) tNGCs) and autologous nerve transplants in an 8-mm sciatic nerve defect in rats. Using a combination of micro-computed tomography and histological analyses, we were able to prove that the use of silk^(+) tNGCs induced the growth of blood vessels from the adjacent tissue to the intraluminal neovascular formation. A significantly higher number of blood vessels in the silk^(+) group was found compared with autologous nerve transplants and silk^(–), accompanied by improved axon regeneration at the distal coaptation point compared with the silk^(–) tNGCs at 7 weeks postoperatively. In the 15-mm(critical size) sciatic nerve defect model, we again observed a distinct ingrowth of blood vessels through the tub.l.r walls of silk^(+) tNGCs, but without improved functional recovery at 12 weeks postoperatively. Our data proves that macroporous tNGCs increase the vascular supply of regenerating nerves and facilitate improved axonal regeneration in a short-defect model but not in a critical-size defect model. This study suggests that further optimizatio

关键词： axon regeneration blood vessel functional recovery macroporous nerve lesion peripheral nerve repair sciatic nerve silk-based nerve guidance conduit vascularization