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Global Pe.iatric Pulmonology Alliance.re.omme.dation to stre.gthe. pre.e.tion of pe.iatric se.sonal influe.za unde. COVID-19 pande.ic

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World Journal of Pe.iatrics 2020年第5期16卷 433-437页

作者： Kun-Ling She. Le.la Namazova-Baranova Yong-Hong Yang Gary Wing Kin Wong Lanny J.Rose.wasse. lance e.rode.ald Anne.e.g Ne. Goh e.tan Ke.e. Chris O'Callaghan T.Be.nard Kinane.Basil e.nazir Rina Triasih Rose.ary Horne.Anne.B Chang Jim Butte.y Ruth A.e.ze. Kazunobu Ouchi Hilary Hoe. Varinde. Singh Ge.e.is C.Rive.a Spe.ce. SLi Yu Guan Ling Cao Yue.Jie.Zhe.g Lu-Zhao Fe.g Wu Zhong Zhe.g-De.Xie.Bao-Ping Xu Rong-Jun Lin Ge. Lu Qiang Qin Chun-Me. Zhu Su-Yun Qian Gang Liu Che.g-Song Zhao Zhuang We. Yu-Hong Zhao Global Pe.iatric Pulmonology Alliance.GPPA)e.pe.t Pane. on Infe.tious Dise.se.&COVID-19 China National Clinical Re.e.rch Ce.te. of Re.piratory Dise.se. Department of Respiratory Medicine of Beijing Children's HospitalCapital Medical UniversityNational Center for Children's HealthBeijingChina Pe.iatrics and Child He.lth Re.e.rch Institute Central Clinical HospitalRussian Academy of SciencesMoscowRussian Federation De.artme.t of Re.piratory Shenzhen Children's HospitalShenzhenChina Chine.e.Unive.sity of Hong Kong Hong Kong SARChina UMKC School of Me.icine Kansas CityMOUSA National Immunization Program Chinese Center for Disease Control and PreventionBeijingChina K Wome.'s and Childre.'s Hospital SingaporeSingapore De.artme.t of Pe.iatrics Hadassah Hebrew University Medical CenterJerusalemIsrael UCL Gre.t Ormond Stre.t Institute.of Child He.lth and Gre.t Ormond Stre.t Hospital(GOSH)BRC University College LondonLondonUK Massachuse.ts Ge.e.al Hospital for Childre. BostonMAUSA Childre.'s He.lth Ire.and and Trinity Colle.e.Dublin DublinIreland De.artme.t of Pae.iatric Faculty of MedicinePublic Health and NursingUniversitas Gadjah Mada/Dr.Sardjito HospitalYogyakartaIndonesia Monash Unive.sity MelbourneAustralia Que.nsland Childre.'s Hospital BrisbaneAustralia Monash Childre.'s Hospital Menzies School of Health ResearchMelbourneAustralia Ge.rge.Washington Unive.sity WashingtonDCUSA De.artme.t of Pe.iatrics Kawasaki Medical SchoolKurashiki-CityJapan De.artme.t of Pe.iatrics University of Dublin Trinity CollegeDublinIreland Lady Hardinge.Me.ical Colle.e.and Assoc Kalawati Saran Childre.'s Hospital New DelhiIndia Ce.te. for Me.ical and Allie. He.lth Scie.ce. New Era UniversityQuezon Citythe Philippines Global Pe.iatric Pulmonology Alliance Hong Kong SARChina De.artme.t of Re.piratory the Children's Hospital Affiliated to the Capital Institute of PediatricsBeijingChina School of Population Me.icine.and Public He.lth Chinese Academy of Medical Sciences/Peking Union Medical CollegeBeijingChina National e.gine.ring Re.e.rch Ce.te. for the.e.e.ge.cy Drug BeijingChina Nati

The.World He.lth Organization(WHO)announce. COVID-19 as a global pande.ic in March of 2020[1].The.COVID-19 pande.ic may pe.sist for a long pe.iod of *** pre.e.tion and control be.ome. a comple. and challe.ging task,and such e.forts should be.*** ge.e.al me.sure.,such as social distancing,face.masks,re.piratory hygie.e.and hand sanitization,will be.r fruits for de.re.sing spre.d of othe. re.piratory illne.se. including influe.za,the.spe.ific pre.e.tion through vaccination is a ke. focus e.pe.ially in the.upcoming winte. and spring se.sons[2].

关键词： pre.e.tion influe.za sustaine.

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Nature.大规模研究揭示生命所必需的基因

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现代生物医学进展 2016年第31期16卷 I0002-I0003页

作者： Dickinson, Mary e. Fle.nike., Ann M. Ji, Xiao Te.oul, Lydia Wong, Michae. D. White. Jacque.ine.K. Me.han, Te.re.ce.F. We.inge., Wolfgang J. We.te.be.g, He.rik Adissu, Hibre. Bake., Candice.N. Bowe., Lyne.te.Brown, Jame. M. Caddle. L. Brianna Chiani, France.co Clary, Dave.Cle.k, Jame. Daly, Mark J. De.e.re. Jame. M. Doe. Bre.dan Dolan, Mary e. e.ie. Sarah M. Fuchs, He.mut Gailus-Durne., Vale.ie.Galli, Antone.la Gambadoro, Ale.sia Galle.os, Juan Guo, Shiying Horne., Ne.l R. Hsu, Chih-We. Johnson, Sara J. Kalaga, Sowmya Ke.th, lance C. Lanoue. Louise.Lawson, Thomas N. Le., Monkol Mark, Manue. Arschall, Susan M. Mason, Je.e.y Mce.we., Me.issa L. Ne.bigging, Susan Nutte., Lauryl M. J. Pe.e.son, Ke.in A. Ramire.-Solis, Ramiro Rowland, Douglas J. Ryde., e.ward Samocha, Kaitlin e. Se.vitt, John R. Se.loum, Mohamme. Szoke.Kovacs, Zsombor Tamura, Masaru Trainor, Amanda G. Tudose. Ilinca Wakana, Shige.aru Warre., Jonathan We.dling, Olivia We.t, David B. Wong, Le.ye.n Yoshiki, Atsushi MacArthur, Danie. G. Tocchini-Vale.tini, Glauco P. Gao, Xiang Flice., Paul Bradle., Allan Skarne., William C. Justice. Monica J. Parkinson, He.e. e. Moore. Mark We.ls, Sara Braun, Robe.t e. Sve.son, Kare. L. de.Ange.is, Martin Hrabe.He.ault, Yann Mohun, Tim Mallon, Ann-Marie.He.ke.man, R. Mark Brown, Ste.e.D. M. Adams, David J. Lloyd, K. C. Ke.t McKe.lie. Colin Be.ude., Arthur L. Bucan, Maja Murray, Ste.he. A. De.t Mol Physiol & Biophys Houston TX 77030 USA Toronto Ctr Phe.oge. Toronto ON M5T 3H7 Canada Mt Sinai Hosp Toronto ON M5G 1X5 Canada Univ Pe.n Perelman Sch Med Genom & Computat Biol Program Philadelphia PA 19104 USA Me. Re. Council Harwe.l Mammalian Genet Unit Harwell OX11 0RD Oxon England Mary Lyon Ctr Harwell OX11 0RD Oxon England Hosp Sick Childre. Mouse Imaging Ctr Toronto ON M5T 3H7 Canada We.lcome.Trust Sange. Inst Wellcome Trust Genome Campus Cambridge CB10 1SA England e.rope.n Bioinformat Inst European Mol Biol Lab Wellcome Trust Genome Campus Cambridge CB10 1SD England Me. Univ Vie.na Ctr Anat & Cell Biol A-1090 Vienna Austria Hosp Sick Childre. 555 Univ Ave Toronto ON M5G 1X8 Canada Jackson Lab 600 Main St Bar Harbor ME 04609 USA Univ Calif Davis Mouse Biol Program Davis CA 95618 USA Italian Natl Re. Council CNR Inst Cell Biol & Neurobiol Monterotondo Mouse Clin I-00015 Monterotondo Italy Massachuse.ts Ge. Hosp Analyt & Translat Genet Unit Boston MA 02114 USA Broad Inst MIT & Harvard Program Med & Populat Genet Cambridge MA 02142 USA Ge.man Re. Ctr e.vironm Hlth Helmholtz Zentrum Munchen Inst Expt Genet D-85764 Neuherberg Germany Ge.man Mouse.Clin D-85764 Neuherberg Germany Baylor Coll Me. Dept Mol & Human Genet Houston TX 77030 USA Nanjing Univ Nanjing Biomed Res Inst Collaborat Innovat Ctr Genet & Dev SKL Pharmaceut Biotechnol & Model Anim Res Ctr Nanjing 210061 Jiangsu Peoples R China Univ Strasbourg ICS Infrastruct Natl PHENOMIN F-67404 Illkirch Graffenstaden France Univ Strasbourg INSERM CNRS IGBMC F-67404 Illkirch Graffenstaden France RIKe. BioResource Ctr Tsukuba Ibaraki 3050074 Japan Childre.s Hosp Oakland Res Inst Oakland CA 94609 USA IMPC San Anselmo CA 94960 USA Te.h Univ Munich Sch Life Sci Weihenstephan Chair Expt Genet D-81675 Freising Weihenstephan Germany Ge.man Ctr Diabe. Re. DZD D-85764 Neuherberg Germany Francis Crick Inst Mill Hill Lab Mill Hill London NW1 1AT England Univ Pe.n Perlman

在哺乳动物基因组中。大约三分之一的基因是生命所必需的。在一项新的研究中，来自美国贝勒医学院等多个机构的研究人员描述了这些基因的大规模发现。以及它将如何影响对哺乳动物发育和人类疾病的理解。相关研究结果在线发表在Nature.... 详细信息

在哺乳动物基因组中。大约三分之一的基因是生命所必需的。在一项新的研究中，来自美国贝勒医学院等多个机构的研究人员描述了这些基因的大规模发现。以及它将如何影响对哺乳动物发育和人类疾病的理解。相关研究结果在线发表在Nature.刊上，论文标题为“High—throughput discove.y of nove. de.e.opme.tal phe.otype.”。

关键词：动物基因组生命哺乳动物研究人员人类疾病医学院

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Global Pe.iatric Pulmonology Alliance.GPPA)proposal for COVID-19 vaccination in childre.

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World Journal of Pe.iatrics 2021年第5期17卷 458-461页

作者： lance e.rode.ald Kun-Ling She. Yong-Hong Yang Gary Wing-Kin Wong Le.la Namazova-Baranova Lanny J.Rose.wasse. Ade. S.Alharbi Anne.B.Chang Jim Butte.y Basil e.nazir Ruth A.e.ze. Anne.Goh Hilary Hoe. Rose.ary Home.e.tan Ke.e. Antone.la Muraro Chris O’Callaghan Kazunobu Ouchi Varinde. Singh Jiu-Yao Wang Spe.ce. Li Yu Guanon Yue.Jie.Zhe.g Zhe.gde.Xie.Ge. Lu Yi Jiang Xing-Wang Li Rong-Me.g Jiang Xiao-Chuan Wang Ji-Kui De.g Xiao-Xia Lu Bao-Ping Xu Zhuang We. Lu-Zhao Fe.g Zhe.g-Yan Zhao the.Global Pe.iatric Pulmonology Alliance.GPPA)Counci Global Pe.iatric Pulmonology Alliance.GPPA)e.pe.t Pane. on Infe.tious Dise.se. and COVID-19 National Immunization Program Chinese Center for Disease Control and Prevention.BeijingChina China National Clinical Re.e.rch Ce.te. of Re.piratory Dise.se. Department of RespiratoryBeijing Children's hospital.Capital Medical UniversityNational Center for Children's HealthBeijingChina Be.jing Childre.'s Hospital Capital Medical UniversityNational Center for Children's HealthBeijingChina Chine.e.Unive.sity of Hong Kong.Hong Kong SAR China Pe.iatrics and Child He.lth Re.e.rch Institute Central Clinical HospitalRussian Academy of SciencesMoscowRussian Federation Unive.sity of Missouri-Kansas City School of Me.icine Kansas CityMOUSA Prince.Sultan Military Me.ical City(PSMMC) Ministry of DefenseRiyadhSaudi Arabia Que.nsland Childre.'s Hospital.Brisbane Australia and Menzies School of Health ResearchDarwinAustralia Monash Childre.'s Hospital Monash UniversityMelbourneAustralia Childre.'s He.lth Ire.and and Trinity Colle.e.Dublin DublinIreland Ge.rge.Washington Unive.sity WashingtonDCUSA KK Wome.’s and Childre.’s Hospital SingaporeSingapore De.artme.t of Pe.iatrics University of Dublin Trinity CollegeDublinIreland Monash Unive.sity MelbourneAustralia De.artme.t of Pe.iatrics Hadassah Hebrew University Medical CenterJerusalem.Israel Food Alle.gy Re.e.ral Ce.tre.Ve.e.o Re.ion Padua Unive.sity Hospital PaduaItaly UCL Gre.t Ormond Stre.t Institute.of Child He.lth Great Ormond Street Hospital(GOSH)BRCUniversity College LondonLondonUK De.artme.t of Pe.iatrics.Kawasaki Me.ical School Kurashiki-cityJapan Lady Hardinge.Me.ical Colle.e.and Assoc Kalawati Saran Childre.'s Hospital Bangla Sahib MargNew DelhiIndia Colle.e.of Me.icine National Cheng Kung UniversityTainan CityTaiwanChina VITUP Inte.national Hospital DalianLiaoningChina China Me.icine.e.ucation Association Pe.iatric Committe. BeijingChina De.artme.t of Re.piratory Dise.se Shenzhen Children's Hospital.ShenzhenChina Re.e.rch Unit of Critical Infe.tion in Childre. Chinese Academy of Medical Sciences2019RU016National Clinical Rese

Coronavirus dise.se.2019(COVID-19)re.ains a global *** of August 18,2021,the.numbe. of re.orte. case. has e.ce.de. 207 million globally,with more.than 4.3 million ***-19 has brought de.astating losse. to human *** ove.all crude.mortality rate.is 1-3%.Although pe.iatric de.ths from COVID-19 are.rare.the. do occur,as ove. 9,000 childre. have.die. from COVID-19 globally to date.1].With the.gradual and broad application of COVID-19 vaccine. around the.world,the.rising proportion of case. among childre. and unvaccinate. young adults de.ands *** to World He.lth Organization surve.llance data.

关键词： mortality globally Alliance

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海长矛运载器

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飞航导弹 1990年第6期 14-19页

作者： C.T.Golde. e.e.Spe.r 邢娅

本文介绍了1980～1986年间开展的海长矛反潜武器的设计和研制,海长矛是一种密封式导弹系统,由潜艇水下发射,无控浮至海面,出水,导弹点火并与运载器分离,沿射向飞至预定点,然后分离有效载荷和助推器,投射弹头进入水下,其中,运载器是一个... 详细信息

本文介绍了1980～1986年间开展的海长矛反潜武器的设计和研制,海长矛是一种密封式导弹系统,由潜艇水下发射,无控浮至海面,出水,导弹点火并与运载器分离,沿射向飞至预定点,然后分离有效载荷和助推器,投射弹头进入水下,其中,运载器是一个石墨丝湿法缠绕的夹层结构圆柱体,用来保护导弹,设计中必须考虑的因素有:组装、运输和使用中的环境;流体静水压和发射压力;潜艇上贮存及发射过程的冲击载荷;浮上海面;出水;导弹的飞出。根据设计要求,以及运载器石墨复合材料的结构特点,提出几种特有的设计方案和制造工艺。

关键词：反潜导弹潜射装置运载器

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Impact of the.2010 re.uscitation guide.ine. training on laype.son che.t compre.sions

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World Journal of e.e.ge.cy Me.icine 2015年第4期6卷 270-276页

作者： Audre. L.Ble.e. David G.Buckle. Jiaqi Li Marion Le.ry lance B.Be.ke. Judy A.She. Pe.e. W.Groe.e.e.d Mary e.Putt Be.jamin S.Abe.la De.artme.t of e.e.ge.cy Me.icine.and Ce.te. for Re.uscitation Scie.ce University of Pennsylvania School of Nursing University of Pennsylvania De.artme.t of Me.icine University of Pennsylvania De.artme.t of Biostatistics and e.ide.iology University of Pennsylvania

BACKGROUND: Survival from cardiac arre.t is se.sitive.to the.quality of de.ive.e. CPR. In 2010, update. inte.national re.uscitation guide.ine. e.phasize. de.pe. che.t compre.sions and faste. rate., ye. it is unknown whe.he. training laype.sons using update. guide.ine. re.ulte. in change. CPR pe.formance. We.hypothe.ize. that laype.sons taught CPR using the.2010 guide.ine. pe.forme. de.pe. and faste. compre.sions than those.taught using the.2005 ***: This work re.re.e.ts a se.ondary analysis of a study conducte. at e.ght hospitals whe.e.family me.be.s of hospitalize. cardiac patie.ts we.e.traine. in CPR. An initial cohort was traine. using the.2005 guide.ine., and a subse.ue.t cohort was traine. using the.2010 guide.ine.mate.ials. Post training, CPR skills we.e.quantifie. using a re.ording ***: Be.we.n May 2009 to August 2013, 338 subje.ts comple.e. the.asse.sme.t. Among the.subje.ts, 176 re.e.ve. 2005 training and 162 unde.we.t 2010 training. The.me.n compre.sion rate.in the.2005 cohort was 87(95%CI 83–90) pe. minute. and in the.2010 cohort was 86(95%CI 83–90) pe. minute.P=ns), while.the.me.n compre.sion de.th was 34(95%CI 32–35) mm in the.2005 cohort and 46(95%CI 44–47) mm in the.2010 cohort(Pe.2010 CPR guide.ine. re.ulte. in a statistically significant incre.se.in traine.s' compre.sion de.th but the.e.was no change.in compre.sion rate. Ne.e.the.e.s, the.majority of CPR pe.forme. by traine.s in both cohorts was be.ow the.guide.ine.re.omme.dation, highlighting an important gap be.we.n training goals and traine. pe.formance.

关键词： Cardiopulmonary re.uscitation Cardiac arre.t Sudde. de.th e.ucation Guide.ine.

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Silve. re.oval from molte. le.d through zinc powde. inje.tion

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Transactions of Nonfe.rous Me.als Socie.y of China 2014年第2期24卷 544-552页

作者： V.H.GUTIéRRe.-PéRe. A.CRUZ-RAMíRe. M.VARGAS-RAMíRe. e.PALACIOS-Be.S R.G.SáNCHe.-ALVARADO e.IQIe Instituto Politécnico NacionalUPALM 07738 México D.F. México CIIM-UAe. Carretera Pachuca-Tulancingo Km 4.5 42084 PachucaHgo. México

A silve. re.oval proce.s was carrie. out on a Pb-Ag alloy through zinc powde. inje.tion of thre. diffe.e.t size. （3.55, 44.4 and 734.8μm） with a top subme.ge. lance using nitroge. as carrying gas. The.highe. silve. re.oval was obtaine. for the.zinc powde. size.of 44.4μm, while.the.lowe.t silve. re.oval e.ficie.cy was attaine. for the.smalle. particle.size. The.AgZn phase.was de.e.te. in the.slag for the.44.4 and 734.8μm particle.size. by XRD, which was in agre.me.t with Se.-e.S analysis. e.pe.ime.tal be.avior was e.plaine. according to the.me.ting and re.ide.ce.time.of the.inje.te. particle..

关键词： le.d silve. particle.size powde. inje.tion re.ide.ce.time de.ilve.ing ratio

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转炉复合锥度分体式氧枪的研究与应用

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钢铁 1999年第7期34卷 19-21页

作者：陈峨顾宪强张满仓荆有利齐忠希鞍山热能研究院本溪钢铁(集团)有限责任公司

介绍了一种新型转炉炼钢氧枪——复合锥度分体式氧枪。该氧枪具有枪体粘渣易于自动脱落、换枪速度快、操作稳定、喷溅少、金属收得率高、可减轻工人的劳动强度等优点，经济效益和社会效益十分可观。

关键词：转炉炼钢锥度分体式氧枪氧气顶吹转炉

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先进的煤粉喷吹动态模型

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世界钢铁 2013年第2期13卷 10-15页

作者： Ricardo S N Motta Wolfgang Birk Luíz e.Souza 李青 Ie.e 吕勒奥理工大学

介绍了最新的用于高炉煤粉喷吹(PCI)的非线性动态模型。开发了一个针对当前最新PCI喷吹站的新的模拟方法。模型考虑了所有的物理动力学定律以及与数字控制系统(DCS)相联的气动传输变量。模型在同样的用于工业级设备控制的DCS中实时运行... 详细信息

介绍了最新的用于高炉煤粉喷吹(PCI)的非线性动态模型。开发了一个针对当前最新PCI喷吹站的新的模拟方法。模型考虑了所有的物理动力学定律以及与数字控制系统(DCS)相联的气动传输变量。模型在同样的用于工业级设备控制的DCS中实时运行。验证采用了专为检验模型设计的最新质量流量计,此设备新引入的检验变量展示了基于动态模型的热量、压力曲线和颗粒速率模型的功能。凭借一个现代控制策略,模型主要用于提高煤粉流量控制的稳定性,同时防止低速高固气比条件下喷枪的阻塞。

关键词：动态模型喷煤高炉炼铁

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2月龄婴儿出生前后暴露于选择性5-羟色胺再摄取抑制剂药物后的疼痛反应

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世界核心医学期刊文摘（儿科学分册） 2006年第9期2卷 51-52页

作者： Obe.lande. T.F. Grunau R.e. Fitzge.ald C. 郭战宏 Biobe.avioral Re.e.rch Unit Centre for Community Child Health Research4480 Oak StVancouverBCCanada Dr.

Obje.tive. In this prospe.tive.study,we.e.amine. biobe.avioral re.ponse. to acute.proce.ural pain at 2 months of age.in infants with pre.atal and postnatal se.e.tive.se.otonin re.ptake.inhibitor (SSRI) me.ication e.posure. Base. on pre.ious findings showing re.uce. pain re.ponse. in ne.borns afte. pre.atal e.posure.we.hypothe.ize. that alte.e. pain re.ctivity would also be.found at 2 months of age. Me.hods. Facial action (Ne.natal Facial Coding Syste.) and cardiac autonomic re.ctivity de.ive. from the.re.piratory activity and he.rt rate.variability (HRV) re.ponse. to a painful e.e.t (he.l-lance)we.e.compare. be.we.n 3 groups of infants:(1) infants with pre.atal SSRI e.posure.alone.(n=11; fluoxe.ine.n=2; paroxe.ine.n =9); (2) infants with pre.atal and postnatal SSRI (via bre.st milk)-e.posure.(total n=30; fluoxe.ine.n=6; paroxe.ine.n=20; se.traline.n=4); and (3) control infants (n=22; none.pose.)-during base.ine.lance,and re.ove.y pe.iods. Me.sure. of mate.nal mood and drug le.e.s we.e.also obtaine.,and Bayle. Scale. of Infant De.e.opme.t-II we.e.administe.e. at age. 2 and 8 months. Re.ults. Facial action incre.se. in all groups imme.iate.y afte. the.lance but was significantly lowe. in the.pSe.group during the.lance pe.iod. HR among infants in the.pSe.and ppSe.groups was significantly lowe. during re.ove.y. Using me.sure. of HRV and the.transfe. re.ationship be.we.n he.rt rate.and re.piration,e.pose. infants had a gre.te. re.urn of parasympathe.ic cardiac modulation in the.re.ove.y pe.iod,whe.e.s a sustaine. sympathe.ic re.ponse.continue. in control infants. Although postnatal e.posure.via bre.st milk was e.tre.e.y low whe. infant drug le.e.s could be.de.e.te. in ppSe.infants,change. in HR and HRV from lance to re.ove.y we.e.gre.te. compare. among infants with le.e.s too low to be.quantifie.. Ne.the. mate.nal mood nor the.pre.e.ce.of clonaze.am influe.ce. pain re.ponse.. Conclusions. Blunte. facial-action re.ponse. we.e.obse.ve. among infants with pre.atal SSRI e.po

关键词：再摄取抑制剂疼痛反应出生前色胺 SSRI 药物治疗新生儿期出生后舍曲林神经行为

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医务人员职业暴露监测分析

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中华医院感染学杂志 2015年第13期25卷 3109-3111页

作者：袁素娥李映兰谭德明中南大学湘雅医院感染病科湖南长沙410008 中南大学湘雅医院护理部湖南长沙410008

目的探讨医务人员职业暴露人群分布、高危环节以及暴露源等,为制定职业防护措施、预防职业暴露后感染提供依据。方法利用"湘雅感染监测管理系统"开展监测,分析2011年8月-2013年8月上报的医务人员发生职业暴露数据。结果两年上报254人次... 详细信息

目的探讨医务人员职业暴露人群分布、高危环节以及暴露源等,为制定职业防护措施、预防职业暴露后感染提供依据。方法利用"湘雅感染监测管理系统"开展监测,分析2011年8月-2013年8月上报的医务人员发生职业暴露数据。结果两年上报254人次职业暴露事件,职业暴露人群以临床护士最高,200人次占78.74%,工龄≤6年人员发生职业暴露达208人次占81.90%,针刺伤是职业暴露最主要方式,达213人次占83.86%,暴露源确定感染乙型肝炎病毒、丙型肝炎病毒、戊型肝炎病毒、苍白密螺旋体、人类免疫缺陷病毒等血源性病原体达121人次占47.64%,确认职业暴露后发生丙型肺炎病毒感染两人,感染率为8.70%,坚持完成1年聚乙二醇干扰素联合利巴韦林抗病毒治疗获得痊愈。结论落实标准预防、推广无针注射和无针输液,是降低医务人员职业暴露有效措施;暴露后遵医嘱及时预防性用药,追踪监测、尽早诊断急性感染、积极抗病毒治疗,是预防暴露后感染以及感染后发展为慢性病的有力保障。

关键词：血源性病原体职业暴露标准预防锐器伤接触后预防

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