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Modeling historical budget for β-Hexachlorocyclohexane(HCH)in the Arctic Ocean:A contrast to α-HCH

Environmental Science and Ecotechnology 2023年第2期14卷 18-28页

作者： Pu-Fei Yang robie w.macdonald Hayley Hung Derek C.G.Muir Roland Kallenborn Anatoly N.Nikolaev wan-Li Ma Li-Yan Liu Yi-Fan Li International Joint Research Center for Persistent Toxic Substances(IJRC-PTS) State Key Laboratory of Urban Water Resource and EnvironmentSchool of EnvironmentHarbin Institute of TechnologyHarbin150090China International Joint Research Center for Arctic Environment and Ecosystem(IJRC-AEE) Polar AcademyHarbin Institute of TechnologyHarbin150090China Institute of Ocean Sciences Department of Fisheries and OceansSidneyBCV8L 4B2Canada Centre for Earth Observation Science University of ManitobaWinnipegR3T 2N2Canada Air Quality Processes Research Section Environment and Climate Change CanadaTorontoOntarioCanada Canada Centre for Inland waters Environment and Climate Change CanadaBurlingtonOntarioCanada Faculty of Chemistry Biotechnology and Food Sciences(KBM)Norwegian University of Life Sciences(NMBU)NOe1433 AsNorway Institute of Natural Sciences North-Eastern Federal UniversityRussia IJRC-PTS-NA TorontoOntarioM2N 6X9Canada

The historical annual loading to,removal from,and cumulative burden in the Arctic Ocean for β-hexachlorocyclohexane(β-HCH),an isomer comprising 5e12%of technical HCH,is investigated using a mass balance box model from 1945 to *** the 76 years,loading occurred predominantly through ocean currents and river inflow(83%)and only a small portion via atmospheric transport(16%).β-HCH started to accumulate in the Arctic Ocean in the late 1940s,reached a peak of 810 t in 1986,and decreased to 87 t in 2020,when its concentrations in the Arctic water and air were~30 ng m^(-3)and~0.02 pg m^(-3),*** though β-HCH and α-HCH(60e70%of technical HCH)are both the isomers of HCHs with almost identical temporal and spatial emission patterns,these two chemicals have shown different major pathways entering the *** from α-HCH with the long-range atmospheric transport(LRAT)as its major transport pathway,β-HCH reached the Arctic mainly through long-range oceanic transport(LROT).The much higher tendency of β-HCH to partition into the water,mainly due to its much lower Henry's Law Constant than α-HCH,produced an exceptionally strong pathway divergence with β-HCH favoring slow transport in water and α-HCH favoring rapid transport in *** concentration and burden of β-HCH in the Arctic Ocean are also predicted for the year 2050 when only 4.4-5.3 t will remain in the Arctic Ocean under the influence of climate change.

关键词： β-Hexachlorocyclohexane Arctic Ocean Mass balance model Budget Air-water exchange

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Persistent organic pollutants in global surface soils:Distributions and fractionations

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Environmental Science and Ecotechnology 2024年第2期18卷 13-27页

作者： Yi-Fan Li Shuai Hao wan-Li Ma Pu-Fei Yang wen-Long Li Zi-Feng Zhang Li-Yan Liu robie wmacdonald International Joint Research Center for Persistent Toxic Substances(IJRC-PTS) State Key Laboratory of Urban Water Resource and EnvironmentHarbinInstitute of TechnologyHarbin150090China International Joint Research Center for Arctic Environment and Ecosystem(IJRC-AEE) Polar AcademyHarbin Institute of Technology(PA-HIT)Harbin150090China Heilongjiang Provincial Key Laboratory of Polar Environment and Ecosystem(HPKL-PEE) Harbin150090China IJRC-PTS-NA TorontoONM2J 3N8Canada College of the Environment and Ecology Xiamen UniversityXiamenChina Institute of Ocean Sciences Department of Fisheries and OceansP.O.Box 6000SidneyBCV8L 4B2Canada Centre for Earth Observation Science University of ManitobaWinnipegR3T 2N2Canada

The distribution and fractionation of persistent organic pollutants(POPs)in different matrices refer to how these pollutants are dispersed and separated within various environmental *** is a significant study area as it helps us understand the transport efficiencies and long-range transport potentials of POPs to enter remote areas,particularly polar *** study provides a comprehensive review of the progress in understanding the distribution and fractionation of *** focus on the contributions of four intermedia processes(dry and wet depositions for gaseous and particulate POPs)and determine their transfer between air and *** processes are controlled by their partitioning between gaseous and particulate phases in the *** distribution patterns and fractionations can be categorized into primary and secondary *** are developed to quantificationally study the primary and secondary distributions and fractionations of *** analysis results suggest that the transfer of low molecular weight(LMw)POPs from air to soil is mainly through gas diffusion and particle deposition,whereas high molecular weight(HMw)POPs are mainly via particle ***-POPs tend to be trapped near the source,whereas LMw-POPs are more prone to undergo long-range atmospheric *** crucial distinction elucidates the primary reason behind their temperatureindependent primary ***,the secondary distribution and fractionation can only be observed along a temperature gradient,such as latitudinal or altitudinal *** animation is produced by a one-dimensional transport model to simulate conceptively the transport of CB-28 and CB-180,revealing the similarities and differences between the primary and secondary distributions and *** suggest that the decreasing temperature trend along latitudes is not the major reason for POPs to be fractionated into the polar ecosystems,but drives the longer-term accumu

关键词： POPs Primary and secondary sources Primary and secondary emissions Primary and secondary distribution patterns Primary and secondary fractionations

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Microglial dysfunction and genetic risk for neurodegenerative disease

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Neural Regeneration Research 2025年第5期20卷 1401-1402页

作者： Debra S.macdonald Jay Penney Department of Biomedical Sciences AVCUniversity of Prince Edward IslandCharlottetownPECanada

Neurodegenerative disorders such as Alzheimer's and Parkinson's diseases a re increasing in prevalence as world populations *** tremendous progress has been made,our understanding of the mechanisms that underlie the development of these diseases remains far from com *** troubling,despite the growing emotional and financial toll being to ken by neurodegenerative disorders,existing treatment options are limited almost exclusively to those that help manage symptoms but that lack the ability to alter the progression of the disease(Liu et al.,2022).

关键词： degenerative diseases

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紫外线辐射和污染相关胁迫因子对北极淡水生态系统的影响

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AMBIO－人类环境杂志 2006年第7期35卷 384-396页

作者： Frederick J.wrona Terry D.Prowse James D.Reist John E.Hobbie Lucie M.J.Lévesque robie w.macdonald warwick F.Vincent 陈欣然 National water Research Institute of Environment Canada Water Science and Technology Directoratec/o Department of GeographyUniversity of Victoria water and Climate Impacts Research Centre National Water Research Institute of Environment CanadaDepartment of GeographyUniversity of Victoria Fisheries and Oceans Canada 501 University Crescent Marine Biological Laboratory The Ecosystems Center National Hydrology Research Centre Environment Canada Dépt de biologie & Centre d'étudesnordiques Université Laval

气候变化很可能作为一种多重胁迫因子,对水生生态系统造成累积的和/或协同的影响。预测的温度上升以及由此带来的降水季节性特征的改变将会增加污染物流入水生生态系统的量,并且会独自提高水生生物体对污染物暴露和影响的易感性。对生... 详细信息

气候变化很可能作为一种多重胁迫因子,对水生生态系统造成累积的和/或协同的影响。预测的温度上升以及由此带来的降水季节性特征的改变将会增加污染物流入水生生态系统的量,并且会独自提高水生生物体对污染物暴露和影响的易感性。对生物区系造成的结果在多数情况下是加和的(累积的)或倍增的(协同的),其总的结果必然是污染物负荷加重,生物放大作用(指有毒化学物质在食物链各环节中的毒性渐进)加强。同温层中臭氧和紫外线辐射季节性特征的变化也会对水生生态系统的结构和功能产生累加或协同的影响。与预测的同温层臭氧量减少这一原因相比,冰层覆盖度的降低可能对水下紫外线暴露产生更为重大的影响。紫外线辐射水平的大幅升高会导致对生物体的损伤增强(生物分子学、细胞学和生理学上的损害,以及物种组成的变化),而生物区系分配用于抵抗紫外线伤害的能量和资源也会增加,有可能使营养水平上的生产力降低。通过光化学途径,元素的通量将会增加。

关键词：紫外线辐射淡水生态系统胁迫因子污染物水生生态系统季节性特征北极有毒化学物质

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Prosecution records reveal pangolin trading networks in China, 2014–2019

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Zoological Research 2021年第5期42卷 666-670页

作者： Xiang-Qin Huang Chris Newman Christina D.Buesching Mei-Ling Shao Yun-Chun Ye Sha Liu David w.macdonald Zhao-Min Zhou Key Laboratory of Southwest China wildlife Resources Conservation(Ministry of Education) China West Normal UniversityNanchongSichuan 637002China wildlife Conservation Research Unit The Recanati-Kaplan CentreDepartment of ZoologyUniversity of OxfordOxford OX135QLUK Cook’s Lake Farming Forestry and Wildlife Inc.(Ecological Consultancy)Queens CountyNova Scotia B0J 2H0Canada Department of Biology Irving K.Barber Faculty of ScienceThe University of British Columbia/OkanaganKelownaBC V1V 1V7Canada Key Laboratory of Environmental Science and Biodiversity Conservation(Sichuan Province) China West Normal UniversityNanchongSichuan 637002China

In a precautionary response to the current coronavirus(COVID-19)pandemic,China’s Ministries permanently banned eating and trading in terrestrial wild(non-livestock)animals on 24 February 2020,and extensively updated the list of Fauna under Special State Protection(LFSSP)in 2020 and 2021,in which pangolins(Manidae spp.)were upgraded to the highest protection *** 509 pangolin prosecution records from China Judgements online prior to these changes(01/01/14–31/12/19),we identified that Guangdong,Guangxi and Yunnan Provinces were hotspots for trade in whole pangolins and their scales.

关键词： trading networks mining

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A novel method for clustering cellular data to improve classification

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Neural Regeneration Research 2025年第9期20卷 2697-2705页

作者： Diek w.wheeler Giorgio A.Ascoli Center for Neural Informatics Structures&PlasticityKrasnow Institute for Advanced Study Bioengineering Department Volgenau School of Engineering George Mason University FairfaxVAUSA

Many fields,such as neuroscience,are experiencing the vast prolife ration of cellular data,underscoring the need fo r organizing and interpreting large datasets.A popular approach partitions data into manageable subsets via hierarchical clustering,but objective methods to determine the appropriate classification granularity are *** recently introduced a technique to systematically identify when to stop subdividing clusters based on the fundamental principle that cells must differ more between than within *** we present the corresponding protocol to classify cellular datasets by combining datadriven unsupervised hierarchical clustering with statistical *** general-purpose functions are applicable to any cellular dataset that can be organized as two-dimensional matrices of numerical values,including molecula r,physiological,and anatomical *** demonstrate the protocol using cellular data from the Janelia MouseLight project to chara cterize morphological aspects of neurons.

关键词： cellular data clustering dendrogram data classification Levene's one-tailed statistical test unsupervised hierarchical clustering

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Response of endemic afroalpine rodents to the removal of livestock grazing pressure

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Current Zoology 2011年第6期57卷 741-750页

作者： Flavie VIAL David w. macdonald Daniel T. HAYDON Boyd Orr Centre for Population and Ecosystem Health Institute of Biodiversity Animal Health and Comparative Medicine College of Medical Veterinary and Life Sciences University of Glasgow Glasgow G12 8QQ UK. wildlife Conservation Research Unit Zoology Department University of Oxford The Recanati-Kaplan Centre Tubney House Tubney OX13 5QL UK.

The Bale Mountains of Ethiopia represent the world＇s largest continuous extent of afroalpine habitat. with a peak combined density of over 8000 individuals/km2, the endemic giant mole rat Tachyoryctes macrocephalus, Blick＇s grass rat Arvi- canthis blicki and the brush-furred mouse Lophuromys melanonyx are the dominant wild herbivores within this ecosystem and may be affected by the presence of high densities of domestic livestock. The purpose of this study was to establish whether these endemic rodent populations could respond to the removal of grazing pressure inside three 0.25 hectare livestock exclosures （paired with grazed control plots） and to determine whether such response was mediated through concomitant changes in the vegetation structure. we hypothesised that livestock grazing negatively affects endemic rodent populations through competition or increased predation risk and we predicted an increase in rodent biomass following the removal of grazing pressure. we found no evidence of rodent populations responding to the removal of livestock after fourteen months. The short-term nature of the ex- perimental design, environmental fluctuations and the ecosystem＇s inherent stochasticity may explain the apparent lack of a sig- nificant response. However, while this study is inconclusive, it emphasises the need for more long-term experimental investiga- tions to assess the effects of domestic grazers on vegetation and on dependent communities. The effects of rapidly increasing livestock numbers in the Bale Mountains will require continued close monitoring of vegetation and endemic animal communities as the afroalpine is altered by external biotic and abiotic forces .

关键词： Afroalpine Bale Mountains Exclosures Livestock grazing Murid rodents

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Genistein:a possible solution for the treatment of Alzheimer’s disease

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Neural Regeneration Research 2025年第10期20卷 2903-2905页

作者： Karolina Pierzynowska Bartosz Karaszewski Grzegorz węgrzyn Department of Molecular Biology University of GdanskGdanskPoland Gdansk Polandand Department of Adult NeurologyFaculty of MedicineMedical University of GdanskGdanskPoland

Neurodegenerative diseases are defined as disorders resulting from the slow and progressive loss of function and eventual death of neural cells that result from the primary pathology of nervous *** can lead to severe nervous system dysfunction,eventually affecting multiple organs and *** hundred neurodegenerative diseases have been described,and owing to their prevalence,severity.

关键词： organs Alzheimer death

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Glia-to-neuron reprogramming to the rescue?

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Neural Regeneration Research 2025年第5期20卷 1395-1396页

作者： Jack w.Hickmott Cindi M.Morshead Department of Surgery University of TorontoTorontoONCanada Donnelly Centre for Cellular and Biomolecular Research TorontoONCanada Institute of Biomedical Engineering University of TorontoTorontoONCanada The KITE Research Institute Toronto Rehabilitation InstituteUniversity Health NetworkTorontoONCanada

Over the last two decades,the dogma that cell fate is immutable has been increasingly challenged,with important implications for regenerative *** brea kth rough discovery that induced pluripotent stem cells could be generated from adult mouse fibroblasts is powerful proof that cell fate can be *** exciting extension of the discovery of cell fate impermanence is the direct cellular reprogram ming hypothesis-that terminally differentiated cells can be reprogrammed into other adult cell fates without first passing through a stem cell state.

关键词： programming passing proof

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Dynamic modeling of a three-dimensional braided composite thin plate considering braiding directions

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Applied Mathematics and Mechanics(English Edition) 2025年第1期46卷 123-138页

作者： Chentong GAO Huiyu SUN Jianping GU w.M.HUANG College of Aerospace Engineering Nanjing University of Aeronautics and Astronautics School of Mechanical and Aerospace Engineering Nanyang Technological University Jiangsu Key Laboratory of Advanced Structural Materials and Application Technology School of Materials Science and EngineeringNanjing Institute of Technology

Currently, there are a limited number of dynamic models available for braided composite plates with large overall motions, despite the incorporation of three-dimensional(3D) braided composites into rotating blade components. In this paper, a dynamic model of 3D 4-directional braided composite thin plates considering braiding directions is established. Based on Kirchhoff's plate assumptions, the displacement variables of the plate are expressed. By incorporating the braiding directions into the constitutive equation of the braided composites, the dynamic model of the plate considering braiding directions is obtained. The effects of the speeds, braiding directions, and braided angles on the responses of the plate with fixed-axis rotation and translational motion, respectively, are investigated. This paper presents a dynamic theory for calculating the deformation of 3D braided composite structures undergoing both translational and rotational motions. It also provides a simulation method for investigating the dynamic behavior of non-isotropic material plates in various applications.

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