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心脏性猝死:定义和病因

国外医学.心血管疾病分册 1987年第2期 93-96页

作者： roberts wc 殷民德

由于心血管疾病而导致突然死亡的病人,其病因可能为心脏性或为非心脏性的(见图1).前者又可分为冠状动脉性和非冠状动脉性两种.在冠状动脉性的病因中,以冠状

关键词：心脏性猝死心血管疾病瓣膜性心脏病粥样硬化性左室流出道肥厚性心肌病植入起搏器动脉瘤破裂电轴左偏无症状

Comment on profitability analysis of a femtosecond laser system for cataract surgery using a fuzzy logic approach

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International Journal of Ophthalmology(English edition) 2017年第3期10卷 497-498页

作者： Harrv William roberts Melody Zhifang Ni David Phillip S. O'Brart Department of Ophthalmology Guy's and St. Thomas' NHS Foundation Trust London SE1 7ET UK King's College London London WC2R 2LS UK 3Division of Surgery Department of Surgery and Cancer Imperial College London St Mary's Hospital London W2 1NY UK Division of Surgery Department of Surgery and CancerImperial College London St Mary's Hospital London W21NY UK

Dear Editor,We read with interest the recently published study by Trigueros et al（[1]）,highlighting the financial and management conditions of femtosecond laser-assisted cataract surgery（FLACS）.The authors derived... 详细信息

关键词： cataract operations carefully nothing something enough sparse currently details comment

In situ calcite U-Pb geochronology by high-sensitivity single-collector LA-SF-ICP-MS

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Science China Earth Sciences 2022年第6期65卷 1146-1160页

作者： Shitou WU Yueheng YANG Nick M.W.roberts Ming YANG Hao WANG Zhongwu LAN Bohang XIE Tianyi LI Lei XU Chao HUANG Liewen XIE Jinhui YANG Fuyuan WU State Key Laboratory of Lithospheric Evolution Institute of Geology and GeophysicsChinese Academy of SciencesBeijing 100029China Innovation Academy for Earth Science Chinese Academy of SciencesBeijing 100029China Geochronology and Tracers Facility British Geological SurveyEnvironmental Science CentreNottinghamNG125GGUK Key Laboratory of Deep Geology and Resources SinopecBeijing 102206China

U-Pb geochronology of calcite using laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS) is an emerging method,with potential applications to a vast array of geological *** to the low levels of U and Pb in calcite,measurement using higher-sensitivity instruments,such as sector field (SF) ICP-MS,have advantages over more commonly used quadrupole (Q) ICP-MS *** a Thermo Element XR ICP-MS,we demonstrate that the Jet+X cone combination with the N_(2) enhancement technique provides the best sensitivity for measuring U and Pb *** higher sensitivity improves the precision of calcite U-Pb isotope measurements,and permits dating at high spatial resolutions (wc-1 reference materials are insignificant (wc-1,Duff Brown Tank,JT,and ASH-15).The results match well with published isotope dilution data,demonstrating the reliability of our ***-3,an andesitic glass,is shown to be an appropriate reference material for both^(207)Pb/^(206)Pb calibration and instrument optimization because of its moderate contents of U(~3.75μg g^(–1)) and Pb (~12.7μg g^(–1)).We further demonstrate that the image-guided approach using LA-ICP-MS elemental mapping is an efficient tool in obtaining robust ages.

关键词： Calcite U-Pb geochronology SF-ICP-MS LA-ICP-MS Sensitivity enhancement Jet sample cones

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Public and health professional epidemic risk perceptions in countries that are highly vulnerable to epidemics: a systematic review

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Infectious Diseases of Poverty 2022年第1期11卷 82-82页

作者： Nada Abdelmagid Francesco Checchi Bayard roberts Faculty of Public Health&Policy London School of Hygiene&Tropical Medicine15-17 Tavistock PlaceLondonWC1H 9SHUK 不详

Background Risk communication interventions during epidemics aim to modify risk perceptions to achieve rapid shifts in population health *** to frequent and often concurrent epidemics may influence how the public and health professionals perceive and respond to epidemic *** review aimed to systematically examine the evidence on risk perceptions of epidemic-prone diseases in countries highly vulnerable to *** We conducted a systematic review using PRISMA *** included peer-reviewed studies describing or measuring risk perceptions of epidemic-prone diseases among the general adult population or health professionals in 62 countries considered highly vulnerable to *** searched seven bibliographic databases and applied a four-stage screening and selection process,followed by quality *** conducted a narrative meta-synthesis and descriptive summary of the evidence,guided by the Social Amplification of Risk *** Fifty-six studies were eligible for the final *** were conducted in eighteen countries and addressed thirteen epidemic-prone ***-five studies were quantitative,six qualitative and five used mixed ***-one studies described epidemic risk perceptions in the general public and nineteen among health *** severity of epidemic-prone diseases appeared high across public and health professional ***,perceived likelihood of acquiring disease varied from low to moderate to high among the general public,and appeared consistently high amongst health *** occupational groups with high exposure to specific diseases,such as bushmeat handlers,reported even lower perceived likelihood than the general *** health professionals,the safety and effectiveness of the work environment and of the broader health system response influenced *** the general population,disease severity,familiarity and controllability of

关键词： Risk perception Epidemic Vulnerability

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对动物实验进行系统评价的必要性(英文)

中国循证医学杂志 2005年第1期5卷 3-5页

作者： Pandora Pound Ian roberts 黄进杜亮 Department of Social Medicine University of Bristol Canynge Hall Whiteladies Road Bristol BS8 2PR London School of Hygiene and Tropical Medicine Keppel Street London WC1E 7HT

Over the last ten to fifteen years, systematic reviews have become accepted as the best means of objectively synthesising and appraising research findings within a defined field. The methodology provides a powerful tool, capable of systematically assessing the quality of evidence in a particular field and identifying where evidence may be either sufficient or lacking.

关键词：系统评价动物实验证据质量治疗效果评价 Meta分析假阴性结果发现必要性手段准确性

关于抗纤维蛋白溶解药治疗创伤性出血大样本随机对照试验的必要性

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中国循证医学杂志 2005年第3期5卷 251-252,264页

作者： Tim Coats Beverley Hunt Ian roberts Haleema Shakur 黄进 University of Leicester 2228Princess Road WestLeicester LE16TPUK Guy's and St Thomas NHS Foundation Trust Trust OfficesSt Thomas StreetGuy's HospitalLondonSE19RTUK CRASH-2 trial co-ordinating centre London School of Hygiene & Tropical MedicineKeppel StreetLondon WC1E7HTUK

This editorial is an open invitation to trauma doctors to participate in the international CRASH-2 trial the rationale for which is outlined below. Those interested in this trial can register via the trial website www. crash2. lshtm, ac. uk. For people at ages 5 to 45 years, trauma is second only to HIV/AIDS as a cause of death. Each year, worldwide, over three million people die as a result of trauma, many after reac-hing hospital . Among trauma patients who do survive to reach hospital, exsanguination is a common cause of death, accounting for nearly half of in-hospital trauma deaths . Central nervous system injury and multi-organ failure account for most of the remainder, both of which can be exacerbated by severe bleeding.

关键词：治疗创伤性抗纤维蛋白随机对照试验出血医生大样本必要性兴趣参与

Identification and treatment of individuals with attentiondeficit/ hyperactivity disorder and substance use disorder: An expert consensus statement

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World Journal of Psychiatry 2023年第3期13卷 84-112页

作者： Susan Young Cyrus Abbasian Zainab Al-Attar Polly Branney Bill Colley Samuele Cortese Sally Cubbin Quinton Deeley Gisli Hannes Gudjonsson Peter Hill Jack Hollingdale Steve Jenden Joe Johnson Deborah Judge Alexandra Lewis Peter Mason Raja Mukherjee David Nutt Jane roberts Fiona Robinson Emma Woodhouse Kelly Cocallis Department of Psychology Psychology Services LimitedCroydon CR97AEUnited Kingdom Department of Psychology Reykjavik UniversityReykjavikIceland Psychiatry-UK Limited Cornwall PL339ETUnited Kingdom ADHD and Autism Oxford ADHD&Autism CentreHeadington OX37BXUnited Kingdom CLC Consultancy Dunkeld PH80AYUnited Kingdom Center for Innovation in Mental Health School of PsychologyFaculty of Environmental and Life SciencesUniversity of SouthamptonSouthampton SO171BJUnited Kingdom Adult ADHD Adult ADHD Clinic LtdOxford OX37RPUnited Kingdom Forensic and Neurodevelopmental Science Institute of PsychiatryPsychology&NeuroscienceKing's College London Institute of PsychiatryLondon SE58AFUnited Kingdom Department of Psychology Institute of PsychiatryPsychology&NeuroscienceKing's College LondonLondon SE58AFUnited Kingdom Department of Psychiatry University of LondonLondon WC1E 7HUUnited Kingdom Department of Psychology Compass Psychology Services LtdLondon BR19DXUnited Kingdom Birribi Ltd Narberth SA677DUUnited Kingdom Halton and Knowsley Adult ADHD Team Merseycare NHS Foundation TrustWinwick WA29WAUnited Kingdom Department of Psychiatry Fulbourn HospitalCambridge CB215EFUnited Kingdom Department of Psychiatry Dr Peter Mason ADHD&Psychiatry Services LimitedLiverpool L19ARUnited Kingdom Adult Neurodevelopmental Service Horizon HouseEpsom KT174QJUnited Kingdom Department of Psychiatry Imperial College LondonLondon WS120NNUnited Kingdom Service User Representative Gloucestershire GL13NNUnited Kingdom Drug&Alcohol Services Surrey&Borders Partnership TrustLeatherhead KT227ADUnited Kingdom Forensic and Neurodevelopmental Sciences Institute of PsychiatryPsychology&NeuroscienceKing's College LondonLondon SE58AFUnited Kingdom Wansbeck General Hospital Northumbria Healthcare NHS Foundation TrustAshington NE639JJUnited Kingdom

Attention-deficit/hyperactivity disorder(ADHD)often co-occurs with substance use(SU)and/or substance use disorder(SUD).Individuals with concurrent ADHD and SU/SUD can have complex presentations that may complicate diagnosis and *** can be further complicated by the context in which services are ***,when working with young people and adults with co-existing ADHD and SU/SUD,there is uncertainty among healthcare practitioners on how best to meet their *** February 2022,the United Kingdom ADHD Partnership hosted a meeting attended by multidisciplinary experts to address these *** presentations providing attendees with an overview of the literature,group discussions were held synthesizing research evidence and clinical *** included:(1)A review of substances and reasons for use/misuse;(2)identification,assessment and treatment of illicit SU/SUD in young people and adults with ADHD presenting in community services;and(3)identification,assessment and treatment of ADHD in adults presenting in SU/SUD community and inpatient *** highlighted inter-service barriers and fragmentation of *** was concluded that a multimodal and multi-agency approach is *** consensus group generated a table of practice recommendations providing guidance on:identification and assessment;pharmacological and psychological treatment;and multi-agency interventions.

关键词： Attention-deficit/hyperactivity disorder Substance use Pharmacokinetics Assessment Treatment Comorbidity

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动物实验和临床试验疗效的比较:系统评价

世界核心医学期刊文摘（心脏病学分册） 2007年第7期3卷 1-2页

作者： Perel P. roberts I. Sena E. 黄浙勇 Crash Trials Coordinating Centre London School of Hygiene and Tropical Medicine London WC1E 7HT

目的：评价动物实验和临床试验治疗效果的一致性。研究设计：系统评价。数据来源：Medline、Embase、SIGLE、NTIS、Science Citation Index、CAB、BIOSIS。研究项目选择：关于在临床试验中疗效（有益或不利）明确的干预措施的动物实验... 详细信息

目的：评价动物实验和临床试验治疗效果的一致性。研究设计：系统评价。数据来源：Medline、Embase、SIGLE、NTIS、Science Citation Index、CAB、BIOSIS。研究项目选择：关于在临床试验中疗效（有益或不利）明确的干预措施的动物实验，包括头部外伤、出血性疾病抗纤溶治疗、急性缺血性脑卒中的溶栓治疗与自由基清除剂替拉扎特治疗、出生前皮质激素预防新生儿呼吸窘迫综合征、二膦酸盐防治骨质疏松症等。评价方法：收集有关研究设计、分配隐藏、随机分组动物数量、动物模型类型、干预措施和结果的数据。

关键词：临床试验疗效动物实验系统新生儿呼吸窘迫综合征急性缺血性脑卒中 Medline 自由基清除剂治疗效果

高灵敏度-单接收杯LA-SF-ICP-MS原位方解石U-Pb定年

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中国科学：地球科学 2022年第7期52卷 1375-1390页

作者：吴石头杨岳衡 Nick M.W.roberts 杨明王浩兰中伍谢博航李天义许蕾黄超谢烈文杨进辉吴福元中国科学院地质与地球物理研究所岩石圈演化国家重点实验室北京100029 中国科学院地球科学创新研究院北京100029 Geochronology and Tracers Facility British Geological SurveyEnvironmental Science CentreNottingham NG125GGUK 中国石油化工集团公司深部地质与资源重点实验室北京102206

激光剥蚀电感耦合等离子体质谱(LA-ICP-MS)方解石U-Pb定年是一种新兴的地质年代学方法,在解决一系列关键地质问题中具有广阔的应用前景.由于方解石中U和Pb含量低,采用高灵敏度扇形磁场电感耦合等离子体质谱仪(SF-ICP-MS)比四极杆电感耦... 详细信息

激光剥蚀电感耦合等离子体质谱(LA-ICP-MS)方解石U-Pb定年是一种新兴的地质年代学方法,在解决一系列关键地质问题中具有广阔的应用前景.由于方解石中U和Pb含量低,采用高灵敏度扇形磁场电感耦合等离子体质谱仪(SF-ICP-MS)比四极杆电感耦合等离子体质谱仪(Q-ICP-MS)更有优势.研究发现对于Thermo Element XR型号的SF-ICP-MS仪器,当采用Jet+X锥组和N_(2)增敏技术时,U和Pb的灵敏度最佳.提高灵敏度不仅能明显改善方解石定年分析精度,而且可在高空间分辨率条件下(wc-1这三个标准物质来说,在激光束斑85μm和能量密度~2.0J cm^(−2)的条件下,由激光剥蚀产生的^(206)Pb/^(238)U动态分馏不显著(wc-1、Duff Brown Tank、JT和ASH-15).结果与已发表的同位素稀释热电离质谱(ID-TIMS)数据相吻合,验证了方法的可靠性.研究进一步证明,基于LA-ICP-MS二维元素成像技术辅助选取样品定年区域可提高方解石U-Pb定年的成功率.

关键词：方解石U-Pb年代学 SF-ICP-MS LA-ICP-MS 高灵敏度 Jet采样锥