检索结果-南通市图书馆

Hypertension,abnormal blood pressure circadian pattern,and frailty:data from the literature

在线全文

学校读者我要写书评

暂无评论

Journal of Geriatric Cardiology 2018年第12期15卷 747-750页

作者： Fabio Fabbian Alfredo De Giorgi Rosaria Cappadona Dario Gozzi Mauro Pasin roberto De Giorgio roberto manfredini Faculty of Medicine Pharmacy and PreventionUniversity of FerraraFerraraItaly Department of Internal Medicine General Hospital of FerraraFerraraItaly

According to the National Health and Nutrition Examination Survey(NHANES)data,more than 65%of people aged≥60 years are hypertensive.[1]Diabetes mellitus,dyslipidemia,obesity and renal failure are frequently associate... 详细信息

关键词： Blood pressure Frailty The elderly

Pulmonary embolism and internal jugular vein thrombosis as evocative clues of Lemierre's syndrome:A case report and review of the literature

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2017年第3期5卷 112-118页

作者： Alfredo De Giorgi Fabio Fabbian Christian Molino Elisa Misurati Ruana Tiseo Claudia Parisi Benedetta Boari roberto manfredini Department of Medical Sciences Clinica Medica UnitSchool of MedicineUniversity of FerraraUniversity Hospital of Ferrara

Lemierre’s syndrome(LS)is an uncommon condition with oropharyngeal infections,internal jugular vein thrombosis,and systemic metastatic septic embolization as the main *** species,a group of strictly anaerobic Gram negative rod shaped bacteria,are advocated to be the main pathogen *** report a case of LS complicated by pulmonary embolism and pulmonary septic emboli that mimicked a neoplastic lung condition.A Medline search revealed 173 case reports of LS associated with internal jugular vein thrombosis that documented the type of *** confirmed high prevalence in young males with Gram negative infections(83.2%).Pulmonary embolism was reported in 8.7% of cases mainly described in subjects with Gram positive infections(OR=9.786;95%CI:2.577-37.168,P=0.001),independently of age and *** four fatal cases were *** is an uncommon condition that could be complicated by pulmonary embolism,especially in subjects with Gram positive infections.

关键词： Lemierre’s syndrome Pulmonary embolism Fusobacterium species Internal jugular vein thrombosis Systemic septic embolization

Heart and lung, a dangerous liaison-Tako-tsubo cardiomyopathy and respiratory diseases: A systematic review

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Cardiology 2014年第5期6卷 338-344页

作者： roberto manfredini Fabio Fabbian Alfredo De Giorgi Marco Pala Alessandra Mallozzi Menegatti Claudia Parisi Elisa Misurati Ruana Tiseo Massimo Gallerani Raffaella Salmi Eduardo Bossone Clinica Medica Azienda Ospedaliera-Universitaria of Ferrara 44124 Cona Ferrara Italy 1st Internal Medicine Unit Azienda Ospedaliera-Universitaria of Ferrara 44124 Cona Ferrara Italy 2nd Internal Medicine Unit Azienda Ospedaliera-Universitaria of Ferrara 44124 Cona Ferrara Italy Cardiology Unit Azienda Ospedaliera-Universitaria of Salerno 84131 Salerno Italy

AIM: To investigate the possible association between Tako-tsubo cardiomyopathy(TTC)-a reversible clini-cal condition mimicking an acute myocardial infarction characterized by multifactorial pathophysiologic mecha-nisms- and respiratory system diseases. METHODS: We systematically searched PubMed and EMBASE medical information sources, to identify the different triggering causes, limiting our search to ar-ticles in English. The search keywords were: "tako-tsubo cardiomyopathy", "takotsubo", "takotsubo cardiomyopa-thy", "broken heart syndrome", "stress-induced cardio-myopathy", "apical ballooning syndrome", and "ampulla cardiomyopathy in combination with respiratory dis-eases, lung, pulmonary disease. For each kind of dis-ease, we registered: author, year and country of study, patient sex, age, concurring situation, and outcome. RESULTS: Out of a total of 1725 articles found, we se-lected 37 papers reporting a total of 38 patients. As ex-pected, most patients were women(81.6%), mean age was 65 ± 10 years. Outcome was favorable in 100% of cases, and all the patients have been discharged un-eventfully in a few days. CONCLUSION: An association between respiratory diseases and TTC is likely to exist. Patients with severe respiratory diseases, due to the high dosages of β2-agonists used or to the need of invasive procedures, are highly exposed to the risk of developing TTC.

关键词： Tako-tsubo cardiomyopathy Stress cardiomyopathy Respiratory diseases Lung Chronic obstructive pulmonary disease Asthma

Dualistic Properties of Cosmetic Formulations Based on Phenylpropanoids from <i>Ajuga reptans</i>

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Cosmetics, Dermatological Sciences and Applications 2013年第3期3卷 64-72页

作者： Silvia Vertuani Paola Ziosi roberto Dal Toso Chiara Beatrice Vicentini Stefano manfredini AmbrosiaLab Ferrara Italy Institute for Biotechnological Research (I.R.B.) Altavilla Vicentina Vicenza Italy Master Course in Cosmetic Science and Technology Department Life Science and Biotechnology University of Ferrara Ferrara Italy

Our continued interest in the research and development of cosmetic active ingredients deriving from natural sources led us to investigate the potential of a purified extract of Ajuga reptans, a plant belonging to the family Labiatae and known for its traditional use in skin healing. The extracts deriving from a biotechnology platform are composed by meristematic cell culture, developed in the frame of a NTFP (non-timber forest product) project, and characterized by high content in phenylpropanoid, of which teupolioside represents the majority component. The latter is a phenylpropanoid glucoside, structurally correlated echinacoside and known in the literature for the antioxidant properties. This study was conducted with the purpose of evaluating the applicability of the Ajuga reptans extract within different cosmetic formulations. In particular, Photochemiluminescence (PCL) was used to proof the antioxidant capacity of cosmetic formulations containing the product, in relation to the change of the title of teupolioside. Furthermore, UVA and UVB filtering properties were also investigated. The results of the study showed relevantly antioxidant capacity of the finished formulation against superoxide anion, which is the main reactive oxygen species responsible for skin aging and significant synergic capacities to filter UV radiation.

关键词： Phenylpropanoids Superoxide Anion Radical Scavenger UV Filter Cosmetic Formulation

Oral frailty and neurodegeneration in Alzheimer’s disease

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2021年第11期16卷 2149-2153页

作者： Vittorio Dibello Madia Lozupone Daniele manfredini Antonio Dibello Roberta Zupo Rodolfo Sardone Antonio Daniele Frank Lobbezoo Francesco Panza Department of Orofacial Pain and Dysfunction Academic Centre for Dentistry Amsterdam(ACTA)University of Amsterdam and Vrije Universiteit AmsterdamAmsterdamThe Netherlands Neurodegenerative Disease Unit Department of Basic MedicineNeuroscienceand Sense OrgansUniversity of Bari Aldo MoroBariItaly School of Dentistry Department of Biomedical TechnologiesUniversity of SienaSienaItaly Azienda Sanitaria Locale(ASL)Bari BariItaly Frailty Phenotypes Research Unit “Salus in Apulia Study”National Institute of Gastroenterology“Saverio de Bellis”Research HospitalCastellana GrotteBariItaly Institute of Neurology Catholic University of Sacred HeartRomeItaly Institute of Neurology Fondazione Policlinico Universitario A.Gemelli IRCCSRomeItaly

Frailty is a critical intermediate status of the aging process with a multidimensional and multisystem nature and at higher risk for adverse health-related outcomes,including falls,disability,hospitalizations,institutionalization,mortality,dementia,and Alzheimer’s *** different frailty phenotypes,oral frailty has been recently suggested as a novel construct defined as a decrease in oral function with a coexisting decline in cognitive and physical *** briefly reviewed existing evidence on operational definitions of oral frailty,assessment and screening tools,and possible relationships among oral frailty,oral microbiota,and Alzheimer’s disease *** underlying mechanism may explain the oral health-frailty links including undernutrition,sarcopenia linked to both poor nutrition and frailty,psychosocial factors,and the chronic inflammation typical of oral *** microbiota may influence Alzheimer’s disease risk through circulatory or neural access to the brain and the interplay with periodontal disease,often causing tooth loss also linked to an increased Alzheimer’s disease *** this bases,COR388,a bacterial protease inhibitor targeting Porphyromonas gingivalis implicated in periodontal disease,is now being tested in a double-blind,placebocontrolled Phase II/III study in mild-to-moderate Alzheimer’s ***,oral status may be an important contributor to general health,including Alzheimer’s disease and latelife cognitive disorders,suggesting the central role of preventive strategies targeting the novel oral frailty phenotype and including maintenance and improvement of oral function and nutritional status to reduce the burden of both oral dysfunction and frailty.

关键词： biomarkers cognitive frailty dementia diet mild cognitive impairment nutritional frailty oral health oral microbiota periodontal disease tooth loss

Liver hemangioma and vascular liver diseases in patients with systemic lupus erythematosus

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2011年第40期17卷 4503-4508页

作者： Annalisa Berzigotti Marilena Frigato Elena manfredini Lucia Pierpaoli Rita Mulè Carolina Tiani Paola Zappoli Donatella Magalotti Nazzarena Malavolta Marco Zoli Department of Internal Medicine Nephrology and Ageing University of Bologna 40138 Bologna Italy UOS Reumatologia Policlinico S Orsola-Malpighi 40138 Bologna Italy

AIM:To investigate whether systemic lupus erythematosus (SLE) is associated with benign focal liver lesions and vascular liver diseases, since these have been occasionally reported in SLE patients. METHODS:Thirty-five consecutive adult patients with SLE and 35 age-and sex-matched healthy controls were evaluated. Hepatic and portal vein patency and presence of focal liver lesions were studied by colour-Doppler ultrasound, computerized tomography and magnetic resonance were used to refine the diagnosis, clinical data of SLE patients were reviewed. RESULTS:Benign hepatic lesions were common in SLE patients (54% vs 14% controls, P < 0.0001), withhemangioma being the most commonly observed lesion in the two groups. SLE was associated with the presence of single hemangioma [odds ratios (OR) 5.05; 95% confidence interval (CI) 1.91-13.38] and multiple hemangiomas (OR 4.13; 95% CI 1.03-16.55). Multiple hemangiomas were associated with a longer duration of SLE (9.9 ± 6.5 vs 5.5 ± 6.4 years; P = 0.04). Imaging prior to SLE onset was available in 9 patients with SLE and hemangioma, showing absence of lesions in 7/9. The clinical data of our patients suggest that SLE pos- sibly plays a role in the development of hemangioma. In addition, a Budd-Chiari syndrome associated with nodular regenerative hyperplasia (NRH), and a NRH associated with hepatic hemangioma were observed, both in patients hospitalized for abdominal symptoms, suggesting that vascular liver diseases should be specifically investigated in this population. CONCLUSION:SLE is associated with 5-fold increased odds of liver hemangiomas, suggesting that these might be considered among the hepatic manifestations of SLE.

关键词：系统性红斑狼疮血管疾病肝脏疾病患者计算机断层扫描 SLE 临床资料多普勒超声

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

家在旅途

英语学习 2003年第8期 52-53页

作者： Lou manfredini 麦兜

久居闹市或各种压力下的人们越来越渴望四海为家的自由。赶快开着自己的RV上路吧,别再错过那美妙的时时刻刻。

关键词： RV 休闲车设计师

Intestinal Protothecosis in a Young Bengal Cat

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Veterinary Medicine 2021年第5期11卷 157-164页

作者： Sara manfredini Luca Formaggini Michele Marino Luigi Venco Clinica Veterinaria Lago Maggiore Dormelletto (NO) Italy Laboratorio Analisi Veterinarie La Vallonea Passirana di Rho (MI) Italy

Background: Intestinal protothecosis is an uncommon and insidious mycotic disease. Only one human case and a few rare cases in dogs have been reported. To the authors’ knowledge, intestinal protothecosis has never been reported in cats. Case description: This paper describes a case of intestinal protothecosis in a nine-month-old male, Bengal cat. The cat presented because of onset of haemorrhagic diarrhoea. Investigations allowed diagnosis of intestinal protothecosis, confirmed by PCR test on faeces. Treatment with itraconazole did not improve the clinical signs. Treatment with nystatin was prescribed and caused improvement in the clinical signs and decreased number of pathogens seen on faecal cytology. PCR on faecal samples was negative two months after treatment, with complete resolution of symptoms. Conclusion: Infection with Prototheca should be part of the list of differential diagnoses for diarrhoea in cats. nystatin was effective in treating the infection in this case;this drug should be considered as a first-line treatment in cats as well as in dogs, in which protothecosis appears to have a poor prognosis. Although protothecosis is not considered a zoonotic disease, cases of algal infections in companion animals might be considered indicators of environmental risks for humans.

关键词： Chronic Diarrhoea Haemorrhagic Colitis Feline Medicine Intestinal Protothecosis Prototheca Infection

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

旅游与历史:概念、挑战及新的研究路径

宁波大学学报（人文科学版） 2016年第6期29卷 1-9页

作者： manfredini Julie 赵冉巴黎第一大学社会史研究中心法国巴黎75004 宁波大学人文与传媒学院浙江宁波315211

20世纪80年代是法国旅游史研究的转折期,法国的历史学者通过其第一批旅游史研究成果,革新了旅游领域的某些定义,开始阐释旅游现象并为其划分周期。借助多学科交叉研究,历史学者在旅游研究中引入了"文化研究"等新思想。旅游迁徙引出的特... 详细信息

20世纪80年代是法国旅游史研究的转折期,法国的历史学者通过其第一批旅游史研究成果,革新了旅游领域的某些定义,开始阐释旅游现象并为其划分周期。借助多学科交叉研究,历史学者在旅游研究中引入了"文化研究"等新思想。旅游迁徙引出的特性/身份问题、区域旅游发展、旅游地类型的开创与扩散等话题也受到其关注。与此同时,还有很多领域值得历史学者深入钻研,如旅游经济,如长期被忽视的法国政府在旅游发展中发挥中的作用,等等。

关键词：历史旅游周期划分特性概念法国