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Physics and astrophysics of strong magnetic field systems with eXTP

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Science China(Physics,Mechanics & Astronomy) 2019年第2期62卷 74-96页

作者： Andrea Santangelo Silvia Zane Hua Feng RenXin Xu Victor Doroshenko Enrico Bozzo Ilaria Caiazzo Francesco Coti Zelati Paolo Esposito Denis González-Caniulef Jeremy Heyl Daniela Huppenkothen Gianluca Israel ZhaoSheng Li Lin Lin roberto mignani Nanda Rea Mauro Orlandini roberto Taverna Hao Tong roberto Turolla Cristina Baglio Federico Bernardini Niccolo'Bucciantini Marco Feroci Felix Fürst Ersin G??ü? Can Güngör Long Ji FangJun Lu Antonios Manousakis Sandro Mereghetti Romana Mikusincova Biswajit Paul Chanda Prescod-Weinstein George Younes Andrea Tiengo YuPeng Xu Anna Watts Shu Zhang Shuang-Nan Zhang Institut für Astronomie und Astrophysik Eberhard Karls Universität Key Laboratory for Particle Astrophysics Institute of High Energy Physics Mullard Space Science Laboratory University College LondonHolmbury St Mary Department of Engineering Physics and Center for Astrophysics Tsinghua University School of Physics Peking University Department of Astronomy University of Geneva Department of Physics and Astronomy University of British Columbia Universitädell’Insubria Anton Pannekoek Institute for Astronomy University of Amsterdam INAF-Osservatorio Astronomico di Brera Center for Data Science New York University INAF-Osservatorio Astronomico di Roma Department of Physics Xiangtan University Department of Astronomy Beijing Normal University INAF-Istituto di Astrofisica Spaziale e Fisica Cosmica Milano Janusz Gil Institute of Astronomy University of Zielona Góra Instituto de Ciencias del Espacio(ICE) CSIC-IEEC INAF-Istituto di Astrofisica Spaziale e Fisica Cosmica Bologna Department of Physics and Astronomy University of Padova School of Physics and Electronic Engineering Guangzhou University NYU Abu Dhabi Saadiyat Campus P.O. NAF Osservatorio di Arcetri Largo Enrico Fermi 5 INAF-Istituto di Astrofisica e Planetologia Spaziali INFN-Roma Tor Vergata European Space Astronomy Centre(ESA/ESAC) Science Operations Department Sabanci University Faculty of Engineering and Natural Sciences Centrum Astronomiczne im.M.Kopernika Department of Physics Sultan Qaboos University Institute of Theoretical Physics Faculty of Mathematics and PhysicsCharles University in Prague Raman Research Institute Sadashivanagar Department of Astronomy University of Washington The George Washington University Physics department 725 21st St NW Scuola Universitaria Superiore IUSS Pavia Palazzo del Broletto

In this paper we present the science potential of the enhanced X-ray Timing and Polarimetry(eXTP) mission for studies of strongly magnetized objects. We will focus on the physics and astrophysics of strongly magnetized objects, namely magnetars, accreting X-ray pulsars, and rotation powered pulsars. We also discuss the science potential of eXTP for QED studies. Developed by an international Consortium led by the Institute of High Energy Physics of the Chinese Academy of Sciences, the eXTP mission is expected to be launched in the mid 2020s.

关键词： neutron stars QED magnetars accreting pulsars eXTP

New opportunities of dendrimers for theranostic approaches to personalized medicine

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Science China Materials 2018年第11期61卷 1365-1366页

作者： Jean-Pierre Majoral Xiangyang Shi Serge mignani Laboratoire de Chimie de Coordination Centre National de la Recherche Scientifique Toulouse France College of Chemistry Chemical Engineering and Biotechnology Donghua University Shanghai China CQM-Centro de Quimica da Madeira MMRG Universidade da Madeira Campus da Penteada 9020-105 Funchal Portugal

Theranostic nanomedicine paradigm, a combination of specific molecular diagnostic tests and specific targeted therapy, involves two topics:therapeutic product efficacies and diagnosis. The first topic concerns identified patients to be treated, whereas the second is to select patients for personalized medicine. Generally, nanotechnology allows developing theranostic strategy

关键词：特定分子诊断测试定向治疗发展现状医疗卫生行业

Multiplexing technology for in vitro diagnosis of pathogens： the key contribution of phosphorus dendrimers

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Science China Materials 2018年第11期61卷 1454-1461页

作者： Jean Pierre Majoral Jean Marie Francois Richard Fabre Alice Senescau Serge mignani Anne-Marie Caminade Laboratoire de Chimie de Coordination du CNRS 31077 Toulouse Cedex 4France LCC-CNRS Universit6 de Toulouse CNRSToulouseFrance Dendris 31670 LabegeFrance LISBP UMR CNRS 5504 INRA 79231077 Toulouse Cedex 04France Universite Paris Descartes PRES Sorbonne Paris Cite CNRS-UMR 860Laboratoire de Chimie et de Biochimie Pharmacologiques et Toxicolgique75006 ParisFrance

After the microbiology based on Pasteur's method and polymerase chain reaction(PCR), the diagnosis company named Dendris has proposed a third-generation of diagnosis enabling the search of a broad range of pathogens with strong sensitivity and specificity. This extraordinary profile was possible thanks to the use of phosphorus dendrimers for which various techniques of deposition on a given support were investigated and described and analyzed in this report.

关键词： phosphorus dendrimers diagnosis DNA arrays multiplexing technology

Recent therapeutic applications of the theranostic principle with dendrimers in oncology

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Science China Materials 2018年第11期61卷 1367-1386页

作者： Serge mignani Joao Rodrigues Helena Tomas Anne-Marie Caminade Regis Laurent Xiangyang Shi Jean-Pierre Majoral Universite Paris Descartes PRES Sorbonne Paris CiteCNRS UMR 860Laboratoire de Chimie et de Biochimie Pharmacologiques et Toxicologique45rue des Saints Peres75006 ParisFrance CQM-Centro de Quimica da Madeira MMRGUniversidade da MadeiraCampus da Penteada9020-105FunchalPortugal School of Materials Science and Engineering/Center for Nano Energy Materials Northwestern Polytechnical UniversityXi＇an 710072China Laboratoire de Chimie de Coordination du CNRS 205 Route de NarbonneBP 4409931077 Toulouse Cedex 4France Universite de Toulouse UPSINPT31077 Toulouse CedexFrance State Key Laboratory for Modification of Chemical Fibers and Polymer Materials College of ChemistryChemical Engineering and BiotechnologyDonghua UniversityShanghai 201620China

At the intersection between treatment and diagnosis, nanoparticles technologies are strongly impacting the development of both therapeutic and diagnostic ***, the development of novel modalities for concomitant noninvasive therapy and diagnostics known as theranostics as a single platform has gained significant interests. These multifunctional theranostic platforms include carbon-based nanomaterials（e.g., carbon nanotubes）, drug conjugates, aliphatic polymers, micelles, vesicles, core-shell nanoparticles, microbubbles and dendrimers bearing different contrast agents and drugs, such as cytotoxic compounds in the oncology domain. Dendrimers emerged as a new class of highly tunable hyperbranched polymers, and have been developed as useful theranostic platforms. Magnetic resonance imaging, gamma scintigraphy, computed tomography and optical imaging are the main techniques developed with dendrimers in the theranostic domain in oncology. Different imaging agents have been used such as Gd（Ⅲ）,19F, Fe2O3（MRI）,76Br（PET）,111In,88Y,153Gd,188Re,131I（SPECT）,177Lu,gold（CT） and boronated groups, siliconnaphthalocyanines,dialkylcarbocyanines and QDs（optical imaging dyes）.

关键词： theranostic platforms dendrimers magnetic resonance imaging gamma scintigraphy imaging computed tomography imaging optical imaging

Observatory science with eXTP

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Science China(Physics,Mechanics & Astronomy) 2019年第2期62卷 97-138页

作者： Jean J.M.in 't Zand Enrico Bozzo JinLu Qu Xiang-Dong Li Lorenzo Amati Yang Chen Immacolata Donnarumma Victor Doroshenko Stephen A.Drake Margarita Hernanz Peter A.Jenke Thomas J.Maccarone Simin Mahmoodifar Domitilla de Martino Alessandra De Rosa Elena M.Rossi Antonia Rowlinson Gloria Sala Giulia Stratta Thomas M.Tauris Joern Wilms XueFeng Wu Ping Zhou Iván Agudo Diego Altamirano Jean-Luc Atteia Nils A.andersson M.Cristina Baglio David R.Ballantyne Altan Baykal Ehud Behar Tomaso Belloni Sudip Bhattacharyya Stefano Bianchi Anna Bilous Pere Blay Joao Braga Sφren Brandt Edward F.Brown Niccolo Bucciantini Luciano Burderi Edward M.Cackett Riccardo Campana Sergio Campana Piergiorgio Casella Yuri Cavecchi Frank Chambers Liang Chen Yu-Peng Chen Jér?me Chenevez Maria Chernyakova ChiChuan Jin Riccardo Ciolfi Elisa Costantini Andrew Cumming Antonino D'Aì Zi-Gao Dai Filippo D'Ammando Massimiliano De Pasquale Nathalie Degenaar Melania Del Santo Valerio D'Elia Tiziana Di Salvo Gerry Doyle Maurizio Falanga XiLong Fan Robert D.Ferdman Marco Feroci Federico Fraschetti Duncan K.Galloway Angelo F.Gambino Poshak Gandhi MingYu Ge Bruce Gendre Ramandeep Gill Diego G?tz Christian Gouiffès Paola Grandi Jonathan Granot Manuel Güdel Alexander Heger Craig O.Heinke Jeroen Homan Rosario Iaria Kazushi Iwasawa Luca Izzo Long Ji Peter G.Jonker Jordi José Jelle S.Kaastra Emrah Kalemci Oleg Kargaltsev Nobuyuki Kawai Laurens Keek Stefanie Komossa Ingo Kreykenbohm Lucien Kuiper Devaky Kunneriath Gang Li En-Wei Liang Manuel Linares Francesco Longo FangJun Lu Alexander A.Lutovinov Denys Malyshev Julien Malzac Antonios Manousakis Ian McHardy Missagh Mehdipour YunPeng Men Mariano Méndez roberto P.mignani Romana Mikusincova M.Coleman Miller Giovanni Miniutti Christian Motch Joonas Nättilä Emanuele Nardini Torsten Neubert Paul T.O'Brien Mauro Orlandini Julian P.Osborne Luigi Pacciani Stéphane Paltani Maurizio Paolillo Iossif E.Papadakis Biswajit Paul Alberto Pellizzoni Uria Peretz Miguel A.Pérez Torres Emanuele Perinati Chanda Prescod-Weinstein Pablo Reig SRON Netherlands Institute for Space Research Department of Astronomy University of Geneva Key Laboratory for Particle Astrophysics Institute of High Energy PhysicsChinese Academy of Sciences School of Astronomy and Space Science Nanjing University INAF-IASF Bologna ASI Via del Politecnico snc INAF-Istituto di Astrofisica e Planetologie Spaziali Institut für Astronomie und Astrophysik Tübingen Universit?t Tübingen NASA Goddard Space Flight Center ICREA&Institute of Space Sciences(IEEC-CSIC) Campus UABCarrer de Can Magrans CSPAR SPA University of Alabama in Huntsville Department of Physics Texas Tech University INAF Osservatorio Astronomico di Capodimonte Leiden Observatory Leiden University Anton Pannekoek Institute University of Amsterdam ASTRON Netherlands Institute for Radio Astronomy Universitat Politecnica de Catalunya(UPC-IEEC) Universitádegli Studi di Urbino‘Carlo Bo’ Max-Planck-Institut für Radioastronomie Dr.Karl-Remeis-Sternwarte and Erlangen Centre for Astroparticle Physics(ECAP) Friedrich Alexander Universit?t Erlangen-Nurnberg Purple Mountain Observatory Chinese Academy of Sciences Instituto de Astrofysíca de Andalucia-CSIC Department of Physics and Astronomy University of Southampton IRAP Universitéde ToulouseCNRSUPSCNES Mathematical Sciences and STAG Research Centre University of Southampton New York University Abu Dhabi Center for Relativistic Astrophysics School of PhysicsGeorgia Institute of Technology Physics Department Middle East Technical University Department of Physics Technion-Israel Institute of Technology INAF Osservatorio Astronomico di Brera Tata Institute of Fundamental Research Dipartimento di Matematica e Fisica Universitàdegli Studi Roma Tre Instituto de Astrofísica de Canarias Instituto Nacional de Pesquisas Espaciais-INPE National Space Institute Technical University of Denmark(DTU Space) Department of Physics and Astronomy Michigan State University INAF Osservatorio Astrofisico di Arcetri Dipartimento di Fisica Universitádegli Studi di Cagliari Department of Physics and A

In this White Paper we present the potential of the enhanced X-ray Timing and Polarimetry(eXTP) mission for studies related to Observatory Science targets. These include flaring stars, supernova remnants, accreting white dwarfs, low and high mass X-ray binaries, radio quiet and radio loud active galactic nuclei, tidal disruption events, and gamma-ray bursts. eXTP will be excellently suited to study one common aspect of these objects: their often transient nature. Developed by an international Consortium led by the Institute of High Energy Physics of the Chinese Academy of Science, the eXTP mission is expected to be launched in the mid 2020s.

关键词： space research in struments nuclear astrophysics flare stars accretion and accretion disks mass loss and stellar winds cataclysmic binaries X-ray binaries supernova remnants active galactic nuclei X-ray bursts gamma-ray bursts gravitational waves

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水解法清洗聚合物过滤芯

国外纺织技术 1999年第12期 12-13页

作者： M.mignani 张胜一

价格和性能是决定过滤工艺的参数,这两个参数是相辅相成的并且直接受清洗系统的巨大影响。清洗工艺很重要,因为它影响过滤芯的寿命和使用性能。所有聚合物过滤器的清洗工艺都包括如下步骤: 清除聚合物、胶体和有机成分; 用化学品清洗... 详细信息

价格和性能是决定过滤工艺的参数,这两个参数是相辅相成的并且直接受清洗系统的巨大影响。清洗工艺很重要,因为它影响过滤芯的寿命和使用性能。所有聚合物过滤器的清洗工艺都包括如下步骤: 清除聚合物、胶体和有机成分; 用化学品清洗无机成分; 检验测试。第一步骤是最关键和最重要的,因为清洗过程的效果就取决于它,实际上,在这个过程没有被

关键词：过滤芯腔体高温下聚合物大分子化合物清洗过程

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水解法清洗聚合物过滤芯

国外纺织技术（纺织针织服装化纤染整） 1999年第12期 12-13页

作者： M.mignani 张胜一

关键词：聚合物清洗工艺过滤芯水解法

乳腺成像时偶然发现椎体骨折:MR定位像的潜在价值

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国际医学放射学杂志 2013年第1期 93-94页

作者： A.Bazzocchi P.Spinnato G.Garzillo F.Ciccarese U.Albisinni S.mignani 赵健仪 Imaging Division Clinical Department of Radiological and Histocytopathological SciencesSant'Orsola-Malpighi HospitalUniversity of BolognaVia Massarenti 940138 BolognaItaly

目的偶然发现椎体骨折是评价骨骼健康情况的关键因素。该研究目的是回顾性评价乳腺MRI的定位像作为显示骨质疏松性椎体骨折的潜在价值。方法 3位肌骨放射学专家采用半定量方法回顾性分析了856例乳腺MRI的矢状定位像以发现椎体骨折。同... 详细信息

目的偶然发现椎体骨折是评价骨骼健康情况的关键因素。该研究目的是回顾性评价乳腺MRI的定位像作为显示骨质疏松性椎体骨折的潜在价值。方法 3位肌骨放射学专家采用半定量方法回顾性分析了856例乳腺MRI的矢状定位像以发现椎体骨折。同时研究病人的病史和基本信息。回顾正式的乳腺MRI与既往的影像学检查,以确定病人病史中是否有椎体骨折或其他相关骨病的情况。结果 856例病人[21～89岁,平均(54.7±12.2)岁]中,780例(91.1%)由于肿瘤原因而进行MRI检查,76例(8.9%)由于非肿瘤因素而参与本研究;57例的MRI定位像不能达到诊断要求而被排除。剩余799例中,71例(8.9%)MRI定位像中发现椎体骨折。其中63例(88.7%)的椎体骨折在影像学报告和既往病史中均未提到(P<0.001)。任何乳腺报告中都没有提到椎体骨折。4例病人的MRI定位像中发现了椎体转移瘤。结论系统评价MRI定位像能够获得额外的临床信息,以防止漏诊椎体骨折。在其他影像学检查时,MRI定位像可用于椎体骨折的筛查。

关键词：定位像 MRI 乳腺乳房椎体骨折 MR 潜在价值

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随用随配的纺丝调制装置

国际纺织导报 2009年第1期37卷 21-21页

作者： M．mignani 骆为林（译）行兰（校） MOVE工程公司（意大利）不详

MOVE工程公司和它的姐妹公司Princo公司已着眼于改进工厂纺丝油剂乳液的调制和分配的方法,已制成称为IEMP的组件(图1),这种组件可按需要进行调制,不需任何人力,并具有高度的灵活性,乳化液在线混合水、纺丝油剂和杀菌剂.

关键词：纺丝油剂调制装置 MOVE 混合水乳化液杀菌剂组件