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Cystic dystrophy of the duodenal wall is not always associated with chronic pancreatitis

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World Journal of Gastroenterology 2011年第39期17卷 4349-4364页

作者： Raffaele Pezzilli Donatella Santini Lucia Calculli Riccardo Casadei Antonio Maria Morselli-Labate Andrea Imbrogno Dario Fabbri Giovanni Taffurelli Claudio Ricci Roberto Corinaldesi Pancreas Unit Department of Digestive Diseases and Internal MedicineSant'Orsola-Malpighi Hospital Department of Pathology Sant'Orsola-Malpighi HospitalUniversity of Bologna Department of Radiology Sant'Orsola-Malpighi HospitalUniversity of Bologna Department of Surgery Sant'Orsola-Malpighi HospitalUniversity of Bologna

Cystic dystrophy of the duodenal wall is a rare form of the disease which was described in 1970 by French authors who reported the presence of focal pancreatic disease localized in an area comprising the C-loop of the duodenum and the head of the pancreas.Ger-man authors have defined this area as a"groove".We report our recent experience on cystic dystrophy of the paraduodenal space and systematically review the data in the literature regarding the alterations of this space.A MEDLINE search of papers published between 1966 and 2010 was carried out and 59 paperswere considered for the present study;there were 19 cohort studies and 40 case reports.The majority of patients having groove pancreatitis were middle aged.Mean age was significantly higher in patients having groove carcinoma.The diagnosis of cystic dystrophy of the duodenal wall can now be assessed by multi-detector computer tomography,magnetic resonance imaging and endoscopic ultrasonography.These latter two techniques may also add more information on the involvement of the remaining pancreatic gland not involved by the duodenal malformation and they may help in differentiating"groove pancreatitis"from "groove adenocarcinoma".In conclusion,chronic pan-creatitis involving the entire pancreatic gland was present in half of the patients with cystic dystrophy of the duodenal wall and,in the majority of them,the pan-creatitis had calcifications.

关键词：营养不良症胰腺炎肠壁慢性 MEDLINE 计算机断层扫描十二指肠磁共振成像

Is the pancreas affected in patients with septic shock?——a prospective study

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Hepatobiliary & Pancreatic Diseases International 2011年第2期10卷 191-195页

作者： Raffaele Pezzilli Alessandra Barassi Andrea Imbrogno Dario Fabbri Antonina Pigna Antonio M.Morselli-Labate Roberto Corinaldesi Gianvico Melzi d'Eril Department of Digestive Diseases and Internal Medicine Sant'Orsola-Malpighi Hospital Alma Mater Studiorum University of Bologna Department of Medicine Surgery and OdontoiatricsUniversity of Milan Department of Surgery and Anesthesiology Sant'Orsola-Malpighi Hospital Alma Mater Studiorum University of Bologna

BACKGROUND:Hyperamylasemia can be observed anecdotally during the course of severe sepsis or septic shock.This study aimed to investigate the possibility of pancreatic involvement in patients with septic shock using serum pancreatic enzyme determinations and imaging techniques in 21 consecutive patients with septic shock and 21 healthy subjects as controls. METHODS:The serum activity of pancreatic amylase and lipase was assayed initially in all subjects and 24 and 48 hours after the initial observation in the 21 patients with septic shock All patients also underwent radiological examination to detect pancreatic abnormalities. RESULTS:The serum activity of pancreatic amylase was significantly higher in the 21 patients with septic shock than in the 21 control subjects during the study period while the serum activity of lipase was similar to that of the control subjects.Amylase and lipase serum activity did not significantly changed throughout the study period in the 21 patients with septic shock.None of the patients with pancreatic hyperenzymemia had clinical signs or morphological alterations compatible with acute pancreatitis CONCLUSION:The presence of pancreatic hyperenzymemia in septic shock patients is not a biochemical manifestation of acute pancreatic damage,and the management of these patients should be dependent on the clinical situation and not merely the biochemical results.

关键词： amylase lipase clinical medicine shock sepsis systemic inflammatory response syndrome

Quality of life in chronic pancreatitis

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世界胃肠病学杂志：英文版 2006年第39期12卷 6249-6251页

作者： Raffaele Pezzilli Laura Bini Lorenzo Fantini Elena Baroni Davide Campana Paola Tomassetti Roberto Corinaldesi Department of Internal Medicine University of Bologna Sant'Orsola-Malpighi Hospital. Bologna Italy

In an era such as the present one in which there is a high demand for health services with the associated pressure of controlling spending, health care organizations are concerned about the cost-effectiveness of quality improvement interventions. On the other hand, the impact of the disease and the treatment on the patient’s overall well-being and functioning has become a topic of growing interest not only in clinical research but also in practice. The clinical evaluation of the benefits of specific treatments for chronic, debilitating and incurable diseases should increasingly include formal assessment of patient activity and well-being. Thus, health-related quality of life as subjectively perceived by the patient, is becoming a major issue in the evaluation of any therapeutic intervention, mainly in patients with chronic or difficult diseases where the aim of the intervention is to keep patients either symptom-free and capable of living in the community for a long time or to reduce the discomfort caused by the disease. In this paper, we review the current knowledge on the quality of life assessment in chronic pancreatitis patients.

关键词：生活质量慢性胰腺炎酒精病理

Chronic intestinal pseudo-obstruction

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World Journal of Gastroenterology 2008年第19期14卷 2953-2961页

作者： Alexandra Antonucci Lucia Fronzoni Laura Cogliandro Rosanna F Cogliandro Carla Caputo roberto De Giorgio Francesca Pallotti Giovanni Barbara Roberto Corinaldesi Vincenzo Stanghellini Department of Internal Medicine and Gastroenterology University of Bologna

Chronic intestinal pseudo-obstruction (CIPO) is a se- vere digestive syndrome characterized by derangement of gut propulsive motility which resembles mechanical obstruction, in the absence of any obstructive process. Although uncommon in clinical practice, this syndrome represents one of the main causes of intestinal failure and is characterized by high morbidity and mortality. It may be idiopathic or secondary to a variety of diseases. Most cases are sporadic, even though familial forms with either dominant or recessive autosomal inheritance have been described. Based on histological features in- testinal pseudo-obstruction can be classified into three main categories:neuropathies, mesenchymopathies, and myopathies, according on the predominant involvement of enteric neurones, interstitial cells of Cajal or smooth muscle cells, respectively. Treatment of intestinal pseu- do-obstruction involves nutritional, pharmacological and surgical therapies, but it is often unsatisfactory and the long-term outcome is generally poor in the majority of cases.

关键词：慢性假性肠梗阻免疫组织化学小肠检测肠移植

Enteric neuropathology of congenital intestinal obstruction:A case report

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World Journal of Gastroenterology 2006年第32期12卷 5229-5233页

作者： Giovanni Di Nardo Vincenzo Stanghellini Salvatore Cucchiara Giovanni Barbara Gianandrea Pasquinelli Donatella Santini Cristina Felicani Gianluca Grazi Antonio D Pinna Rosanna Cogliandro Cesare Cremon Alessandra Gori Roberto Corinaldesi Kenton M Sanders roberto De Giorgio Department of Pediatrics Pediatric Gastroenterology Unit University of Rome 'La Sapienza' Rome Italy Department of Internal Medicine and Gastroenterology and Centro di Ricerca Biomedica Applicata (CRBA) Rome Italy 不详 Department of Pathology and Department of Surgery and Transplantation University of Bologna Bologna Italy Department of Physiology and Cell Biology University of Nevada School of Medicine Reno Nevada United States

试验性的证据显示肠的长期的机械亚吸藏可以损坏伤寒神经系统(ENS ) ，尽管在人的数据正在缺乏。我们这里描述伤寒的第一诉讼与内脏的先天的阻塞有关的退化神经病。3 年的 A 和老女孩开始抱怨了呕吐的 9 瞬间，腹的扩张，有空气液体的... 详细信息

试验性的证据显示肠的长期的机械亚吸藏可以损坏伤寒神经系统(ENS ) ，尽管在人的数据正在缺乏。我们这里描述伤寒的第一诉讼与内脏的先天的阻塞有关的退化神经病。3 年的 A 和老女孩开始抱怨了呕吐的 9 瞬间，腹的扩张，有空气液体的便秘在飞机铺平腹的辐射学。她的随后的病历被 3 操作描绘：首先显示出的扩大 duodeno-jejunal 当闭塞的损害不在时循环；第二(2 年以后) 被执行获得扩大的肠的环的完整厚度的活体检视并且在组织病理学说揭示了 hyperganglionosis；第三(在 hyperganglionosis 以后的 9 年被识别) 揭示了 Ladd 被移开的乐队，联系内脏旋转不良被改正。完整厚度的活体检视显示出的重复 intraoperative 与 Cajal 的减少的空隙的房间一起的退化神经病在 Ladd 的乐队下面在阻塞和正常的神经与肌的层上面在扩大的环联网的伤寒。病人容忍了的在最近的外科以后的一年口头的喂并且很好，建议那先天(部分) 在人的小肠的机械阻塞能唤起类似于在肠的机械吸藏的动物模型发现的那些的 ENS 的进步适应变化。如此的 ENS 变化模仿在肠的伪阻塞观察的神经元畸形。

关键词：肠神经病理学先天性肠阻塞神经系统治疗

Solitary Intramedullary Spinal Cord Metastasis from Colon Carcinoma: A Case Report and Literature Review

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Open Journal of Modern Neurosurgery 2014年第1期4卷 47-51页

作者： Pierpaolo Lunardi Rodolfo corinaldesi Tommaso Lunardi roberto Floris University of Perugia Perugia Italy University of Rome Tor Vergata Roma Italy

It is extremely rare for cancer to present as an intramedullary spinal cord metastasis. The authors report on a case of a 74-year-old woman presenting with progressive tetraparesis to metastatic colon adenocarcinoma in the spinal cord. A review of the literature reveals that intramedullary localization is associated with a very short life expectancy, with a median survival of 3-4 months from the time of the diagnosis;nevertheless microsurgical removal of tumor can improve quality of life.

关键词： Spinal Cord Metastasis

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膨胀剂对纤维增强水泥基复合材料性能的影响

膨胀剂与膨胀混凝土 2015年第4期 26-32,14页

作者： Valeria corinaldesi 贾福杰

本文研究了纤维增强水泥基复合材料(FRCCs)和超高性能混凝土(UHPCs),通过掺加氧化钙类膨胀剂降低干燥收缩开裂风险。测试了三种不同的金属纤维:平直钢纤维、镀铜弯钩纤维、镀铜直纤维。测试了容重、抗压强度、抗弯强度以及干燥收缩变形... 详细信息

本文研究了纤维增强水泥基复合材料(FRCCs)和超高性能混凝土(UHPCs),通过掺加氧化钙类膨胀剂降低干燥收缩开裂风险。测试了三种不同的金属纤维:平直钢纤维、镀铜弯钩纤维、镀铜直纤维。测试了容重、抗压强度、抗弯强度以及干燥收缩变形。通过压汞试验和电镜扫描测试了FRCC的微观结构。试件成型后24h进行80℃预处理。结果证明,氧化钙类膨胀剂会减小干燥收缩;并且与镀铜纤维复合使用可以增加抗弯强度。这种协同效应可以归因于在纤维和水泥浆的表面生成了锌酸钙,明显增加了纤维与水泥基体间的结合力。

关键词：镀铜纤维水泥基复合材料耐久性膨胀剂纤维增加混凝土抗弯强度 UHPC

口腔种植体的锐钛涂层表面抑制细菌定植的有效性:一项导向性体内实验

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中国口腔医学继续教育杂志 2020年第2期23卷 114-121页

作者： Alessandro Cucchi Mole Lucia Rinaldi Claudio Marchetti Giuseppe corinaldesi 许彬欣(译) 张新春(审) 不详中山大学光华口腔医学院 510000

目的:种植体周围炎的一级预防是种植体远期成功的关键因素.因此评估不同种植体表面的抗菌效能是至关重要的。本实验旨在探究相比于无涂层.种植体的锐钛涂层表面是否能减少细菌定植,并研究种植体细菌定植情况随时间变化的规律。材料与方... 详细信息

目的:种植体周围炎的一级预防是种植体远期成功的关键因素.因此评估不同种植体表面的抗菌效能是至关重要的。本实验旨在探究相比于无涂层.种植体的锐钛涂层表面是否能减少细菌定植,并研究种植体细菌定植情况随时间变化的规律。材料与方法:选择18名应用种植修复的患者.于每名受试者两个相邻牙位分别植入有锐钛涂层及无涂层的种植体。在此后的4个时间点于每个种植体的4个位点取生物膜样本.并以多聚酶链式反应(PCR)检测伴放线放线杆菌.牙龈卟啉单胞菌.齿垢密螺旋体.福塞斯坦纳菌及中间普氏菌5种细菌的定植率。结果:因1名受试者中途退出及2个种植体未能形成骨结合.12个月的随访中我们取得植入的36个种植体中的32例.并于每个时间点收集到128个样本:总共512个生物膜样本参与分析。对比锐钛涂层与无涂层种植体.细菌种类及定植率无显著差别。但是.锐钛涂层组未见福塞斯坦纳菌生长。在第12月观察时间点可见锐钛涂层组种植体周骨水平更高,且差异有统计学意义。此外未见其他临床或影像学数据出现显著差异。结论:本实验中.相比无涂层种植体.锐钛涂层种植体的细菌定植情况似乎无显著差异。但是.本实验发现锐钛涂层组未见福塞斯坦纳菌生长,及在第12月观察时间点种植体周骨水平显著更高.这两点有必要进一步实验.以获得更有意义的结论。

关键词：锐钛有涂层材料口腔种植体骨结合种植体周围炎多聚酶链式反应

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静止电磁场的角动量

大学物理 1987年第10期6卷 28-29页

作者： E. corinaldesi 张庆楠西南民族学院

并不是每个学生都会爽快地相信《费曼物理学》第二卷17.4[1]中的佯谬可以用初始就存在的静止电磁场角动量来解释.这里p是动量密度,它正比于坡印廷矢量[2],这一角动量在电流切断后变为0。为保证电磁角动量与机械角动量构成的总角动量守恒... 详细信息

并不是每个学生都会爽快地相信《费曼物理学》第二卷17.4[1]中的佯谬可以用初始就存在的静止电磁场角动量来解释.这里p是动量密度,它正比于坡印廷矢量[2],这一角动量在电流切断后变为0。为保证电磁角动量与机械角动量构成的总角动量守恒,塑料圆盘将开始旋转. 角动量概念是与绕轴运动相联系的.圆偏振波具有角动量似乎易于理解,因为电场与磁场均绕波传播的方向旋转,静止场具有角动量则难于理解. 下面我们来考虑一个可以绕轴自由旋转的力学系,它可借其上所带的电荷同时激发电场和磁场.它与费曼盘不是雷同的模型,但具有某些相同特性而且优点在于计算简便.唯一要付出的代价是,由于要忽略麦克斯韦位移电流,即电场对时间的导教,要作一些近似. 考虑两个无限长的同轴(。轴)圆筒,两筒可绕轴无摩擦地同向或反向旋转.内筒半径为R并均匀带电,沿。轴单位长度上的电荷为人0,外筒也均匀带电,半径为*’B,单位长上带电为一人J与厂分别为内外简单位长度转动惯量,中与/分别为它们的角速度(不必有相同的符号). 设单位长上力矩为。力与。’力(不必同号)分别作用在内外筒上.力矩之和不能与机械角动量矩的变化率相等,因为转动带电圆筒产生的磁场随时间变化要产生感应...

关键词：电磁场角动量静止物理学佯谬费曼