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The Meat of the Matter: Plant-Based Meat Analogue versus Traditional Meat Product Nutritional Quality

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Food Science and Human Wellness 2024年

作者： Arshia Shireen Amanda j.wright Department of Human Health and Nutritional Sciences， University of Guelph Guelph， Ontario， Canada bDepartment of Human Health and Nutritional Sciences， University of Guelph Guelph， Ontario， Canada

Plant-based meat analogues (PBMA) are formulated to mimic the sensory characteristics of traditional meat products (TMP) using vegetarian ingredients and are increasingly popular with the trend towards plant-based diets， even among meat-eating consumers. This narrative review compared the nutritional quality of PBMA and TMP to broaden the discussion on the suitability of simulated meat products to substitute TMP， while exploring other attributes for their comparison. The complexity of PBMA and TMP means they are not entirely interchangeable. Importantly， PBMA health effects extend beyond their basic nutrient content and quality. Postprandial metabolism and satiety， for example， can be affected by product formulation， ingredient interactions， and thermomechanical processing involved in producing organoleptically acceptable PBMA. There are specific opportunities for low-sodium PBMA products to contribute to a healthy shift toward plant-based diets. In conclusion， PBMA cannot be assumed to be healthier than TMP. They should be designed with comprehensive consideration of composition and processing to ensure they support consumers who are adopting plant-based diets in realizing the theoretical health benefits.

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肠道真菌对造血干细胞移植临床结果的影响

肠道真菌对造血干细胞移植临床结果的影响

Disaster Awareness and Preparedness Among Older Adults in Canada Regarding Floods, Wildfires, and Earthquakes

中国菌物学会2023年学术年会

作者：翟冰 Thierry Rolling Mihaela Ola Mergim Gjonbalaj Nicholas L.Tosini Keiko Yasuma Luigi A.Amoretti Emily Fontana roberta j.wright jonathan U.Peled Geraldine Butler Ying Taur Tobias M.Hohl 中国科学院深圳先进技术研究院合成生物学研究所斯隆凯特琳癌症研究中心都柏林大学生物分子与生物医学学院

人的肠道微生物群落由细菌、真菌、病毒等微生物共同组成,影响人体多种生理或病理过程。相较于细菌组分,目前对于人体肠道菌群中的真菌组分认识严重不足。我们通过将高精度分析算法引入真菌ITS序列分析,结合培养组学和比较基因组学分析... 详细信息

人的肠道微生物群落由细菌、真菌、病毒等微生物共同组成,影响人体多种生理或病理过程。相较于细菌组分,目前对于人体肠道菌群中的真菌组分认识严重不足。我们通过将高精度分析算法引入真菌ITS序列分析,结合培养组学和比较基因组学分析,建立了一套可靠的真菌菌群分析平台,并以此为基础对造血干细胞移植初期的患者肠道真菌动态变化进行时序性分析。结合临床数据,我们发现移植前后肠道真菌DNA的载量和多样性并无显著区别,但其组分发生了巨大变化,其中有近20%的患者在移植后免疫抑制期出现明显的近平滑念珠菌定植扩增,同时具有特殊的细菌菌群组分变化。尤为重要的是,具有近平滑念珠菌肠道定植的患者比其他患者具有显著恶化的总存活率,以及更高的真菌菌血症发生风险。通过比较念珠菌菌血症患者血液分离株和肠道分离株的全基因组序列,我们发现血液感染发生前一周左右,造成感染的菌株就已经在肠道中发生定植。综上所述,本项研究系统分析了造血干细胞移植过程中人体肠道真菌的动态变化,预示着精准干预肠道病原真菌的定植扩增可以有效预防血液感染,并提高患者总存活率。

关键词：真菌菌群造血干细胞移植真菌菌血症培养组学比较基因组学真菌细菌互作

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International journal of Disaster Risk Science 2024年第2期15卷 198-212页

作者： Evalyna Bogdan Rachel Krueger julie wright Kyle Woods Shaieree Cottar School of Administrative Studies Disaster and Emergency Management ProgramYork UniversityTorontoOntario M3J 1P3Canada Department of Geography and Environmental Management University of WaterlooWaterlooOntario N2L 3G1Canada Partners for Action Faculty of EnvironmentUniversity of WaterlooWaterlooOntario N2L 3G1Canada

Older adults are significantly impacted by natural hazards and disasters that are exacerbated by climate change. Understanding their awareness and preparedness is essential for enhancing disaster resilience. This study investigated the attitudes, actions, and recommendations of older adults regarding natural hazards that pose risks in their geographic area—specifically floods, wildfires, and/or earthquakes in Canada. Methods for this study included survey and focus groups with older adults(n = 161 and n = 10, respectively) and other high-risk groups from across Canada, that are vulnerable to these natural hazards. The main findings from this study are that current awareness and preparedness among older adults is low, though stronger perceptions of risks are associated with risks specific to geographic locations where respondents live. Several barriers, such as hazard vulnerability misperceptions, cost-related reasons, and lack of hazard awareness have resulted in low awareness and preparedness among these populations. The two main recommendations arising from this research are:(1) improve awareness and preparedness with tailor-made emergency preparedness materials for older adults;and(2) adopt community-based approaches to disaster preparedness through existing community groups to strengthen social connections with a focus on locally specific hazards. The findings from this research can be applied to other hazards, including heatwaves and pandemics.

关键词： Canada Community-based disaster risk management Disaster awareness and preparedness Disaster resilience Natural hazards Older adults

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So What’s the Big Deal With Information Literacy in the United States?

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图书情报知识 2010年第5期27卷 26-31页

作者： Alease j.wright New Horizons Information Age Services Springdale MD USA

2010年7月13日,"国际大学生信息素养能力邀请赛"在武汉大学成功举办。本次邀请赛的主题是"信息沟通世界:培育未来信息职业的领导者"。"邀请赛"是武汉大学首届学生社团国际交流营(2010年7月11～18日)的活动之一,也是武汉大学信息管理学... 详细信息

2010年7月13日,"国际大学生信息素养能力邀请赛"在武汉大学成功举办。本次邀请赛的主题是"信息沟通世界:培育未来信息职业的领导者"。"邀请赛"是武汉大学首届学生社团国际交流营(2010年7月11～18日)的活动之一,也是武汉大学信息管理学院信息职业领导力夏季研究班(2010年7月12～14日)的活动之一。活动期间特邀请了信息素养教育领域的专家授课;美洲、欧洲和亚洲不同国家和地区的多所大学共选派30名选手参加了比赛,并通过听课、撰写论文以及讨论等方式,围绕信息素养进行了学习和探讨。竞赛与课程的内容丰富了学员的信息素养知识,提升了学员的信息素养能力。现将其授课与讨论的主要内容刊出,以飨读者。

关键词：信息素养能力国际交流大学生 the With 2010年 So 专题

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Reviewing the Safe Shipping of Lithium-Ion and Sodium-Ion Cells:A Materials Chemistry Perspective

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Energy Material Advances 2021年第1期2021卷 1-12页

作者： Ashish Rudola Christopher j.wright jerry Barker Faradion Limited The Innovation Centre217 PortobelloSheffield S14DPUK

High energy density lithium-ion(Li-ion)batteries are commonly used *** decades’worth of intense research has led to a good understanding on several aspects of such ***,the issue of their safe storage and transportation is still not widely understood from a materials chemistry *** international regulations require Li-ion cells to be shipped at 30%SOC(State of Charge)or *** this article,the reasons behind this requirement for shipping Li-ion batteries are firstly reviewed and then compared with those of the analogous and recently commercialized sodium-ion(Na-ion)*** such alkali-ion batteries,the safest state from their active materials viewpoint is at 0V or zero energy,and this should be their ideal state for storage/***,a“fully discharged”Li-ion cell used most commonly,composed of graphitebased anode on copper current collector,is not actually at 0V at its rated 0%SOC,contrary to what one might expect—the detailed mechanism behind the reason for this,namely,copper dissolution,and how it negatively affects cycling performance and cell safety,will be summarized *** will be shown that Na-ion cells,capable of using a lighter and cheaper aluminum current collector on the anode,can actually be safely discharged to 0V(true 0%SOC)and beyond,even to reverse polarity(negative voltages).It is anticipated that this article spurs further research on the 0V capability of Na-ion systems,with some suggestions for future studies provided.

关键词： cycling summarized alkali

21-Component compositionally complex ceramics: Discovery of ultrahigh-entropy weberite and fergusonite phases and a pyrochlore–weberite transition

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journal of Advanced Ceramics 2022年第4期11卷 641-655页

作者： Mingde QIN Heidy VEGA Dawei ZHANG Sarath ADAPA Andrew j.wright Renkun CHEN jian LUO Department of Nano Engineering University of California San DiegoLa Jolla 92093USA Department of Chemistry and Biochemistry University of California San DiegoLa Jolla 92093USA Program of Materials Science and Engineering University of California San DiegoLa Jolla 92093USA Department of Mechanical and Aerospace Engineering University of California San DiegoLa Jolla 92093USA

Two new high-entropy ceramics(HECs)in the weberite and fergusonite structures,along with the unexpected formation of ordered pyrochlore phases with ultrahigh-entropy compositions and an abrupt pyrochlore–weberite transition,are discovered in a 21-component oxide *** the Gibbs phase rule allows 21 equilibrium phases,9 out of the 13 compositions examined possess single HEC phases(with ultrahigh ideal configurational entropies:~2.7kB per cation or higher on one sublattice in most cases).Notably,(15RE_(1/15))(Nb_(1/2)Ta_(1/2))O_(4) possess a single monoclinic fergusonite(C2/c)phase,and(15RE_(1/15))_(3)(Nb_(1/2)Ta_(1/2))_(1)O_(7) form a single orthorhombic(C222_(1))weberite phase,where 15RE_(1/15) represents Sc_(1/15)Y_(1/15)La_(1/15)Pr_(1/15)Nd_(1/15)Sm_(1/15)Eu_(1/15)Gd_(1/15)Tb_(1/15)Dy_(1/15)Ho_(1/15)Er_(1/15)Tm_(1/15) Yb_(1/15)Lu_(1/15).Moreover,a series of eight(15RE_(1/15))_(2+x)(Ti_(1/4)Zr_(1/4)Ce_(1/4)Hf_(1/4))_(2−2x)(Nb_(1/2)Ta_(1/2))_(x)O_(7) specimens all exhibit single phases,where a pyrochlore–weberite transition occurs within 0.75

关键词： compositionally complex ceramics high-entropy ceramics(HECs) weberite pyrochlore fergusonite ultrahigh-entropy ceramics many-component ceramics

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Imaging approach for jaw and maxillofacial bone tumors with updates from the 2022 World Health Organization classification

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World journal of Radiology 2024年第8期16卷 294-316页

作者： Woongsoon john Choi Peggy Lee Penelope C Thomas Tanya j Rath Monique A Mogensen roberta W Dalley Pattana Wangaryattawanich Division of Neuroradiology Department of RadiologyUniversity of Washington School of MedicineSeattleWA 98195United States Department of Radiology M&S Radiology AssociatesSan AntonioTX 78217United States Division of Oral Radiology University of Washington School of DentistrySeattleWA 98195United States Division of Neuroradiology Department of RadiologyMayo ClinicPhoenixAZ 85054United States

jaw and maxillofacial bone lesions encompass a wide variety of both neoplastic and non-neoplastic *** lesions can arise from various tissues,including bone,cartilage,and soft tissue,each presenting distinct challenges in diagnosis and *** some pathologies exhibit characteristic imaging features that aid in diagnosis,many others are *** overlap often necessitates a multimodal imaging approach,combining techniques such as radiographs,computed tomography,and magnetic resonance imaging to achieve a diagnosis or narrow the diagnostic *** article provides a comprehensive review of the imaging approach to jaw and maxillofacial bone tumors,including updates on the 2022 World Health Organization classification of these *** relevant anatomy of the jaw and dental structures that is important for accurate imaging interpretation is discussed.

关键词： Mandible Maxilla Maxillofacial jaw Tumor Neoplasm

Mechanical environment for in vitro cartilage tissue engineering assisted by in silico models

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Biomaterials Translational 2023年第1期4卷 18-26页

作者： Rob jess Tao Ling Yi Xiong Chris j.wright Feihu Zhao Department of Computing Hong Kong Polytechnic UniversityHong Kong Special Administrative RegionChina

Mechanobiological study of chondrogenic cells and multipotent stem cells for articular cartilage tissue engineering(CTE)has been widely *** mechanical stimulation in terms of wall shear stress,hydrostatic pressure and mechanical strain has been applied in CTE in *** has been found that the mechanical stimulation at a certain range can accelerate the chondrogenesis and articular cartilage tissue *** review explicitly focuses on the study of the influence of the mechanical environment on proliferation and extracellular matrix production of chondrocytes in vitro for *** multidisciplinary approaches used in previous studies and the need for in silico methods to be used in parallel with in vitro methods are also *** information from this review is expected to direct facial CTE research,in which mechanobiology has not been widely explored yet.

关键词： cartilage tissue engineering in silico modelling mechanical stimulation mechanobiology

Transarterial embolization is an acceptable bridging therapy to hepatocellular carcinoma prior to liver transplantation

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World journal of Transplantation 2024年第2期14卷 126-134页

作者： Gabriel Lazzarotto-da-Silva Leandro A Scaffaro Mauricio Farenzena Lucas Prediger Rafaela K Silva Flávia Heinz Feier Tomaz j M Grezzana-Filho Pablo D Rodrigues Alexandre de Araujo Mario Reis Alvares-da-Silva roberta C Marchiori Cleber Rosito Pinto Kruel Marcio Fernandes Chedid Department of Liver Transplant and Hepatobiliary Surgery Unit Hospital de Clínicas de Porto AlegrePorto Alegre 90035-007Brazil Department of Interventional Radiology Unit Hospital de Clínicas de Porto AlegrePorto Alegre 90035-007Brazil Department of Gastroenterology and Hepatology Hospital de Clínicas de Porto AlegrePorto Alegre 90035-007Brazil

BACKGROUND Hepatocellular carcinoma(HCC)is an aggressive malignant neoplasm that requires liver transplantation(LT).Despite patients with HCC being prioritized by most organ allocation systems worldwide,they still have to wait for long *** therapies(LRTs)are employed as bridging therapies in patients with HCC awaiting *** largely used in the past,transarterial embolization(TAE)has been replaced by transarterial chemoembolization(TACE).However,the superiority of TACE over TAE has not been consistently shown in the *** To compare the outcomes of TACE and TAE in patients with HCC awaiting *** All consecutive patients with HCC awaiting LT between 2011 and 2020 at a single center were *** patients underwent LRT with either TACE or *** patients also underwent percutaneous ethanol injection(PEI),concom-itantly or in different treatment *** choice of LRT for each HCC nodule was determined by a multidisciplinary *** primary outcome was waitlist dropout due to tumor progression,and the secondary outcome was the occurrence of adverse *** the subset of patients who underwent LT,complete pathological response and post-transplant recurrence-free survival were also *** Twelve(18.5%)patients in the TACE group(only TACE and TACE+PEI;n=65)and 3(7.9%)patients in the TAE group(only TAE and TAE+PEI;n=38)dropped out of the waitlist due to tumor progression(P log-rank test=0.29).Adverse events occurred in 8(12.3%)and 2(5.3%)patients in the TACE and TAE groups,respectively(P=0.316).Forty-eight(73.8%)of the 65 patients in the TACE group and 29(76.3%)of the 38 patients in the TAE group underwent LT(P=0.818).Among these patients,complete pathological response was detected in 7(14.6%)and 9(31%)patients in the TACE and TAE groups,respectively(P=0.145).Post-LT,HCC recurred in 9(18.8%)and 4(13.8%)patients in the TACE and TAE groups,respectively(P=0.756).Posttransplant recurrence-free survival was simila

关键词： Hepatocellular carcinoma Transarterial embolization Transarterial chemoembolization Liver transplantation Locoregional therapy Bridging