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Transanal eco-Doppler evaluation after hemorrhoidal artery embolization

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World Journal of Gastroenterology 2024年第17期30卷 2332-2342页

作者： roberta Tutino Tommaso Stecca Fabrizio Farneti Marco Massani Giulio Aniello Santoro dipartimento Chirurgia Generale e Specialistica AOU Cittàdella Salute e della Scienza di TorinoTorino 10126Italy division of General Surgery 1 Treviso Regional HospitalAULSS 2 Marca TrevigianaTreviso 31100Italy division of Radiology Treviso Regional HospitalAULSS 2 Marca TrevigianaTreviso 31100Italy Tertiary Referral Pelvic Floor Center Division of General Surgery 2AULSS 2 Marca TrevigianaTreviso 31100Italy

BACKGROUND Hemorrhoidal artery embolization(Emborrhoid)is a novel method for the treatment of severe hemorrhoidal *** having a technical success rate of 93%-100%,the clinical success ranges between 63%and 94%,with a rebleeding rate of 13.6%.AIM To evaluate the effectiveness of this procedure in reducing hemorrhoidal flow and hemorrhoidal *** This prospective observational pilot study was conducted at division of General Surgery 1 and Tertiary Referral Pelvic Floor Center,Treviso Regional Hospital,*** a 2 months period(February-March 2022),consecutive patients with hemorrhoidal bleeding scores(HBSs)≥4,Goligher scores of II or III,failure of non-operative management,and a candidate for Emborrhoid were *** ultrasound with eco-Doppler was performed preoperatively and 1 month after the *** primary endpoint was to quantify the changes in arterial hemorrhoidal flow after *** secondary endpoint was to evaluate the correlation between the flow changes and the *** Eleven patients underwent *** overall pretreatment mean systolic peak(MSP)was 14.66 cm/*** highest MSP values were found in the anterior left lateral(17.82 cm/s at 1 o’clock and 15.88 cm/s at 3 o’clock)and in the posterior right lateral(14.62 cm/s at 7 o’clock and 16.71 cm/s at 9 o’clock)quadrants of the anal *** treatment,the overall MSP values were significantly reduced(P=0.008)although the correlation between MSP and HBS changes was weak(P=0.570).A statistical difference was found between distal embolization compared with proximal embolization(P=0.047).However,the coil landing zone was not related to symptoms improvement(P=1.000).A significant difference in MSP changes was also reported between patients with type 1 and type 2 superior rectal artery(SRA)anatomy(P=0.040).No relationship between hemorrhoidal grades(P=1.000),SRA anatomy(P=1.000)and treatment outcomes was *** The preliminary findings of this pilo

关键词： Hemorrhoidal artery embolization Hemorrhoidal embolization Hemorrhoidal vascularization Transanal eco-Doppler Transanal ultrasound

Profiles of the Headspace Volatile Organic and Essential Oil Compounds from the Tunisian Cardaria draba (L.) Desv. and Its Leaf and Stem Epidermal Micromorphology

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Phyton-International Journal of Experimental Botany 2024年第4期93卷 725-744页

作者： Wissal Saadellaoui Samiha Kahlaoui Kheiria Hcini Abir Haddada Noomene Sleimi roberta Ascrizzi Guido Flamini Fethia Harzallah-Skhiri Sondes Stambouli-Essassi Laboratory of Biodiversity Biotechnology and Climate Change(LR11-ES09)Faculty of Sciences of TunisUniversity of Tunis El ManarTunis1060Tunisia Laboratory RME-Resources Materials and EcosystemsFaculty of Sciences of BizerteUniversity of CarthageJarzounaBizerte7021Tunisia dipartimento di Farmacia Universitàdi PisaVia Bonanno 33Pisa56126Italy Laboratory of Bioresources:Integrative Biology and Valorization(LR14-ES06) High Institute of Biotechnology of MonastirUniversity of MonastirMonastir5000Tunisia

In this work, we investigated aroma volatiles emanated by dry roots, stems, leaves, flowers, and fruits of Cardariadraba (L.) Desv. growing wild in Tunisia and its aerial part essential oils (EOs) composition. A total of 37 volatileorganic compounds (96.7%–98.9%) were identified;4 esters, 4 alcohols, 7 hydrocarbons, 12 aldehydes, 5 ketones,1 lactone, 1 organosulfur compound, 2 organonitrogen compounds, and 1 acid. The hydrocarbons form the maingroup, representing 49.5%–84.6% of the total detected volatiles. The main constituent was 2,2,4,6,6-pentamethylheptane(44.5%–76.2%) reaching the highest relative percentages. Forty-two compounds were determined in thetwo fractions of EOs, representing 98.8% and 97.2% of the total oil composition, respectively. The principal componentswere hexadecanoic acid (34.6%), 6-methyl-5-hepten-2-one (18.3%), decanal (15.0%), 6,10,14-trimethyl-2-pentadecanone (13.2%), and n-pentacosane (13%). Micromorphological details of the leaf and stem epidermisusing light microscopy revealed polygonal cells with sinuous walls in the adaxial and abaxial leaf surfaces andnearly rectangular and long ones with linear and thick walls for the stem epidermis. The stomata complexes wereanisocytic in the leaf epidermis and mainly anisocytic and rarely paracytic in the stem epidermis. Non-glandulartrichomes were unbranched and long with an acute apex or short with a convex apex. The glandular ones wereidentified for the first time in this species. They were short-stalked with a large secretory head. The highest stomatalindex (17.02%) was recorded in the abaxial leaf surface. The identification of headspace volatiles and essentialoil compounds can be used to characterize this species, and the various epidermis micromorphologicalfeatures are very useful for biosystematics taxonomic studies within Brassicaceae.

关键词： Cardaria draba aroma profile essential oils epidermis trichomes

Cold ischemia time in liver transplantation:An overview

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World Journal of Hepatology 2024年第6期16卷 883-890页

作者： Manuela Cesaretti Alessandro Izzo roberta Anna Pellegrino Alessandro Galli Orestes Mavrothalassitis Department of HPB and Liver Transplantation Brotzu HospitalCagliari 09122Italy Department of Nanophysic Istituto Italiano di TecnologiaGenova 16163Italy Department of Critical Care Medicine and Anesthesia ASST Papa Giovanni XXIIIBergamo 24100Italy Department of Anesthesia and Perioperative Care University of California San FranciscoSan FranciscoCA 94143United States

The standard approach to organ preservation in liver transplantation is by static cold storage and the time between the cross-clamping of a graft in a donor and its reperfusion in the recipient is defined as cold ischemia time(CIT).This simple definition reveals a multifactorial time frame that depends on donor hepatectomy time,transit time,and recipient surgery time,and is one of the most important donor-related risk factors which may influence the graft and recipient’s ***,the growing demand for the use of marginal liver grafts has prompted scientific exploration to analyze ischemia time factors and develop different organ preservation *** review details the CIT definition and analyzes its different *** also explores the most recent strategies developed to implement each timestamp of CIT and to protect the graft from ischemic injury.

关键词： Cold ischemia time Liver transplantation Organ donation Donation after cardiac death Warm ischemia time Machine perfusion

Omega-3 fatty acids for the treatment of non-alcoholic fatty liver disease

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World Journal of Gastroenterology 2012年第41期18卷 5839-5847页

作者： Matteo Nicola Dario di Minno Anna Russolillo roberta Lupoli Pasquale Ambrosino Alessandro di Minno Giovanni Tarantino Department of Clinical and Experimental Medicine Regional Reference Centre for Coagulation Disorders"Federico II" University80131 NaplesItaly Department of Endocrinology and Oncology "Federico II" University80131 NaplesItaly

Non-alcoholic fatty liver disease （NAFLD） has been recognized as a major health burden. It is the most important cause of chronic liver disease and a major in- dependent cardiovascular risk factor. Lacking a definite treatment for NAFLD, a specific diet and an increase in physical activity represent the most commonly used therapeutic approaches. In this review, major literature data about the use of omega-3 polyunsaturated fatty ac- ids （n-3 PUFAs） as a potential treatment of NAFLD have been described, n-3 PUFAs, besides having a beneficial impact on most of the cardio-metabolic risk factors （hy- pertension, hyperlipidemia, endothelial dysfunction and atherosclerosis） by regulating gene transcription factors [i.e., peroxisome proliferator-activated receptor （PPAR） cz, PPARy, sterol regulatory element-binding protein-i, carbohydrate responsive element-binding protein], im- pacts both lipid metabolism and on insulin sensitivity. In addition to an enhancement of hepatic beta oxidation and a decrease of the endogenous lipid production, n-3 PUFAs are able to determine a significant reduction of the expression of pro-inflammatory molecules （tumor necrosis factor-~ and interleukin-6） and of oxygen reac- tive species. Further strengthening the results of the in vitro studies, both animal models and human interven- tion trials, showed a beneficial effect of n-3 PUFAs on the severity of NAFLD as expressed by laboratory pa- rameters and imaging measurements. Despite available results provided encouraging data about the efficacy of n-3 PUFAs as a treatment of NAFLD in humans, well- designed randomized controlled trials of adequate size and duration, with histological endpoints, are needed to assess the long-term safety and efficacy of PUFA, as well as other therapies, for the treatment of NAFLD and non-alcoholic steatohepatitis patients. It is worthwhile to consider that n-3 PUFAs cannot be synthesized by the human body and must be derived from exogenous sources （fish oil, flax

关键词： Hepatic steatosis Non-alcoholic fatty liverdisease Omega-3 polyunsaturated fatty acids Animalmodels

Tackling the challenge of controlling the spin with electric field

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National Science Review 2021年第2期8卷 8-9页

作者： roberta Sessoli dipartimento di Chimica ‘Ugo Schiff’ & INSTM RU Università degli Studi di Firenze

Electric(E) fields are commonly employed to control magnetization in some classes of materials such as ***, the extreme confinement of the electric field, for instance under the tip of a scanning tunnel microscope,makes it an ideal tool to manipulate individual spins, generating interest in spins as potential quantum bits. Spins are in fact intrinsic quantum systems that can be manipulated easily by means of pulses of electromagnetic microwaves, as commonly done in magnetic resonance spectroscopies. Although the coupling usually involves the magnetic field of microwaves,

关键词： INdiVIDUAL ATOMS

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油库抗震韧性动态评估模型

中国安全科学学报 2024年第4期34卷 87-92页

作者：陈超谭心鑫王迪李长俊西南石油大学石油与天然气工程学院四川成都610500 代尔夫特理工大学安全科学系荷兰代尔夫特2628 BX 国家石油天然气管网集团北京100028

为解决油库面临地震时的安全管理问题,首先,将抗震韧性定义为油库为保持储存功能表现出的抵御地震破坏、减轻地震次生灾害、适应震后环境和震后快速恢复的能力,并量化油库抗震韧性表现出的4种能力,建立油库抗震韧性评估模型;其次,考虑... 详细信息

为解决油库面临地震时的安全管理问题,首先,将抗震韧性定义为油库为保持储存功能表现出的抵御地震破坏、减轻地震次生灾害、适应震后环境和震后快速恢复的能力,并量化油库抗震韧性表现出的4种能力,建立油库抗震韧性评估模型;其次,考虑到抵御阶段和减轻阶段的不确定性,基于动态蒙特卡罗法,定量评估油库抗震韧性,并获得油库的抗震韧性值;最后,以某地震区域油库为例,验证模型的有效性。结果表明:油库韧性能力的不确定性导致韧性值出现大幅波动;多米诺效应对油库韧性的影响较大,不可忽略;震源距离越远、断层滑移率越小,抗震韧性越高;远离活动断层、预测地震危害、减少应急响应时间等措施可提高抗震韧性。

关键词：油库地震安全韧性抗震韧性动态评估评估模型

Nitrogen Release from Slow-Release Fertilizers in Soils with different Microbial Activities

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Pedosphere 2018年第2期28卷 332-340页

作者： Pierfrancesco NARdi Ulderico NERI Giovanni di MATTEO Alessandra TRINCHERA Rosario NAPOLI roberta FARINA Guntur V. SUBBARAO Anna BENEDETTI CREA-Council for Agricultural Research and Economics Research Center for Agriculture and Environment Via della Navicella 2Rome 00184 (Italy) Japan International Research Center for Agricultural Sciences (JIRCAS) Tsukuba 305-8686 (Japan)

Soil microbial activity is recognized as an important factor affecting nitrogen (N) release from slow-release fertilizers. However,studies on the effect of size and activity of soil microflora on fertilizer degradation have provided contrasting results. To date, no clear relationships exist between soil microbial activity and the release of N from slow-release fertilizers. Hence, the aim of this study was to better understand such relationships by determining the release of N from three slow-release fertilizers in soils with different microbial activities. Soils were amended with urea-formaldehyde (UF), isobutylidene diurea (IBDU), and crotonylidene diurea (CDU). Urea, a soluble fertilizer, was used as the control. Fertilized soil samples were placed in a leaching system, and the release of N was determined by measuring ammonium-N and nitrate-N concentrations in leachates during 90 d of incubation. Non-linear regression was used to fit N leaching rate to a first-order model. In all the treated soils, N was released in the order: urea (89%–100%) > IBDU (59%–94%) >UF (46%–73%) > CDU (44%–56%). At the end of incubation, N released from CDU did not differ (P > 0.05) among soils. On the contrary, UF and IBDU released significantly lower (P dicated that soil microbial size and microbial activity had a marginal effect on fertilizer mineralization.

关键词： ammonium-N crotonylidene diurea isobutylidene diurea nitrate-N non-linear regression urea-formaldehyde

应用3种数据有限方法对印度洋近海金枪鱼类和马鲛类资源评估

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上海海洋大学学报 2024年第3期33卷 728-740页

作者：陈镝安朱江峰耿喆上海海洋大学海洋生物资源与管理学院上海201306 大洋渔业资源可持续开发教育部重点实验室上海201306 农业农村部大洋渔业开发重点实验室上海201306

近些年来印度洋近海金枪鱼类和马鲛类捕捞量上升较快,但因捕捞者多为个体手工渔业或小型工业渔业,渔业统计不完善,缺少传统资源评估所需的完整数据,因此这些鱼种目前缺乏可靠的评估。为了更好地掌握资源状况以制定相应的管理措施,本研... 详细信息

近些年来印度洋近海金枪鱼类和马鲛类捕捞量上升较快,但因捕捞者多为个体手工渔业或小型工业渔业,渔业统计不完善,缺少传统资源评估所需的完整数据,因此这些鱼种目前缺乏可靠的评估。为了更好地掌握资源状况以制定相应的管理措施,本研究使用1950—2020年捕捞量数据,运用CMSY模型(monte carlo catch-msy)、DB-SRA模型(Depletion-based stock reduction analysis)和OCOM模型(Optimized catch-only assessmentmethod)等3种数据有限评估方法对圆舵鲣、扁舵鲣、巴鲣、青干金枪鱼、斑点马鲛、康氏马鲛等6个鱼种资源状况进行评估。基于相对生物量(B/B_(MSY))和相对捕捞死亡率(F/F_(MSY))进行判断,扁舵鲣和斑点马鲛的当前资源状态较为健康[P(B/B_(MSY)>1)=78%,P(F/F_(MSY)1)=78%,P(F/F_(MSY)1)=78%,P(F/F_(MSY)1)=78%,P(F/F_(MSY)1)=33%,P(F/F_(MSY)1)=55%,P(F/F_(MSY)<1)=33%]。3种模型中,CMSY模型和DBSRA模型给出的MSY估计值接近,CMSY模型给出了最为谨慎的评估结果(6个鱼种均存在过度捕捞),而OCOM模型给出的结果最为乐观,表明3种模型对这6个鱼种的资源状况判断有一定差异。敏感性分析显示,参数r以及Bend/K的先验设定均会对CMSY模型结果产生较大的影响;DB-SRA模型对Bt/K敏感,对K较为稳健。从结果上来看,3种模型均可以用于对近海小型金枪鱼和马鲛类的资源评估,但单一方法可能会导致结果偏差。建议在使用数据有限的评估方法时,采用多组参数以及多个方法进行比较分析,以更全面地获得种群资源状况。本研究可以为印度洋近海小型渔业管理提供参考。

关键词：近海金枪鱼马鲛类资源状况数据有限评估方法印度洋

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考虑风光出力动态相关性的场景生成方法

太阳能学报 2024年第8期45卷 256-264页

作者：高帆包道日娜狄彦强张少华内蒙古工业大学能源与动力工程学院呼和浩特010051 中国建筑科学研究院有限公司北京100013 内蒙古恒东集团汇隆煤炭有限责任公司鄂尔多斯017000

针对风光出力的不确定性问题提出一种利用混合Copula函数结合多元正态分布的风光出力场景生成方法。基于风电功率和光伏功率的历史数据建立风光出力的联合分布模型,进一步通过多元正态分布和协方差矩阵生成具有动态相关的风光出力联合... 详细信息

针对风光出力的不确定性问题提出一种利用混合Copula函数结合多元正态分布的风光出力场景生成方法。基于风电功率和光伏功率的历史数据建立风光出力的联合分布模型,进一步通过多元正态分布和协方差矩阵生成具有动态相关的风光出力联合分布序列;采用马尔科夫链蒙特卡洛抽样法生成风光出力场景的随机分布数,通过逆变换法得到相应的风光出力场景;对不同方法生成出力场景进行对比,分析动态相关下风光出力场景的拟合效果和耦合效应。结果验证所提方法的有效性,生成的出力场景能够较好地刻画风光单独出力和耦合出力时的不确定性。

关键词：风光出力混合Copula函数多元正态分布动态相关性场景生成

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