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Non-exhaustive double effort test is reliable and estimates the firs ventilatory threshold intensity in running exercise

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Journal of Sport and Health Science 2018年第2期7卷 197-203页

作者： Lucas Dantas Maia Forte Fúlvia Barros Manchado-Gobatto roberta cunha matheus rodrigues Maria Ceclia Gallani Claudio Alexandre Gobatto School of Applied Science University of Campinas School of Nursing University of Campinas Faculty of Nursing Laval University

Purpose: The present study aimed to investigate the reliability of the non-exhaustive double effort(NEDE) test in running exercise and its associations with the ventilatory thresholds(VT_1 and VT_2) and the maximal lactate steady state(MLSS).Methods: Ten healthy male adults(age: 23 ± 4 years, height: 176.6 ± 6.4 cm, body mass: 76.6 ± 10.7 kg) performed 4 procedures:(1) a ramp test for VT_1 and VT_2 determinations measured by ratio of expired ventilation to O_2 uptake(VE/VO_2) and expired ventilation to CO_2 output(VE/VCO_2) equivalents, respectively;(2) the NEDE test measured by blood lactate concentration(NEDE_(LAC)) and heart rate responses(NEDE_(HR));(3) a retest of NEDE for reliability analysis; and(4) continuous efforts to determine the MLSS intensity. The NEDE test consisted of4 sessions at different running intensities. Each session was characterized by double efforts at the same running velocity(E1 and E2, 180 s), separated by a passive recovery period(90 s rest). LAC and HR values after E1 and E2(in 4 sessions) were used to estimate the intensity equivalent to"null delta" by linear fit. This parameter represents, theoretically, the intensity equivalent to maximal aerobic ***: The intraclass correlation coefficient indicated significant reliability for NEDE_(LAC)(0.93) and NEDE_(HR)(0.79)(both p < 0.05). There were significant correlations, no differences, and strong agreement with the intensities predicted by NEDE_(LAC)(10.1 ± 1.9 km/h) and NEDE_(HR)(9.8 ± 2.0 km/h) to VT_1(10.2 ± 1.1 km/h). In addition, despite significantly lower MLSS intensity(12.2 ± 1.2 km/h), NEDE_(LAC) and NEDE_(HR) intensities were highly correlated with this parameter(0.90 and 0.88, respectively).Conclusion: The NEDE test applied to running exercise is reliable and estimates the VT_1 intensity. Additionally, NEDE intensities were lower but still correlated with VT_2 and MLSS.

关键词： Aerobic exercise Anaerobic threshold Maximal lactate steady state Non-exhaustive protocol Training prescription Ventilatory threshold

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Growing Food on Green Roofs:The First Step of an Interdisciplinary Approach

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Journal of Civil Engineering and Architecture 2019年第11期13卷 694-703页

作者： Eduardo Grala da cunha Celina Maria Britto Correa Viviane Ritter Daniela Hohn roberta Marins Nogueira Peil Helayne Aparecida Maieves Lisandra Fachinello Krebs Mariana Estima Silva Laboratory of Comfort and Energy Efficiency Federal University of PelotasPelotas 96010-020Brazil CNPq(National Council for Scientific and Technological Development) Brasilia71605-170Brazil Post-graduation Program in Familiar Agriculture Production Systems Crop Production DepartmentCollege of AgronomyFederal University of PelotasPelotas 96010-020Brazil Post-graduation Program in Science and Food Technology College of NutritionFederal University of PelotasPelotas 96010-020Brazil College of Architecture and Urbanism Federal University of PelotasPelotas 96010-020Brazil

Under the many available strategies for the adoption of sustainable practices,the urban agriculture emerges as a relevant *** naturation is the vegetative treatment of built surfaces,using plants adapted to the local environmental *** vegetation is a highly relevant element to the regulation and balance of extreme climatic *** also affects buildings thermal comfort and energy use,when assuming functions of control regarding solar radiation,air relative humidity and air *** the role of climate control,the vegetation can also play a role in food *** growing of vegetable crops,spices and medicinal herbs has gained the urban spaces of Brazilian *** growth of plants at home or in the urban environment,described as productive landscape,becomes one of the few ways of contact with the elements of ***,the urban agriculture can create natural spaces in the urban centers,thus,promoting the comfort into two scales:the urban scale and the building *** the other hand,the addition of vegetation for food production on built surfaces assumes a multidisciplinary *** is needed to technically respond to the suitable choice of substrate and plant species,to the nutrition values of the cultivated foods and,therefore,to the building physics that supports the food *** aims of this investigation project are:(i)to increase international partnerships in the subject(the Federal University of Pelotas,in Brazil;the Lund and the ALNARP Universities,in Sweden;the Polytechnic University of Madrid,in Spain;and the Arizona State University,in the United States);(ii)to bring information on both the building energy efficiency and the outdoor microclimate as a consequence of the green roof establishment;(iii)to generate a cultivation guide for food production on ***,this paper presents the first step of the research interdisciplinary approach,which deals with the construction of the Cultivation

关键词： Rooftop farming substrate urban microclimate buildings thermal performance modeling

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Nutritional Screening in a University Hospital:Comparison between Oncologic and Non-Oncologic Patients

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Food and Nutrition Sciences 2015年第1期6卷 75-82页

作者： Selma F.C.cunha Lidiane S.Tanaka roberta G.Salomao Danielle M.Macedo Thatiane D.Santos Fernanda M.Peria Division of Clinical Nutrition Department of Internal MedicineSchool of Medicine of Ribeirao PretoUniversity of Sao PauloRibeirao PretoBrazil Parenteral and Enteral Nutrition Team of Clinical Hospital School of Medicine of Ribeirao PretoUniversity of Sao PauloRibeirao PretoBrazil Division of Oncology Department of Internal MedicineSchool of Medicine of Ribeirao PretoUniversity of Sao PauloRibeirao PretoBrazil

Background & Aims: We compared the screening nutritional data of patients with malignant and non-malignant disease, and classified their nutritional risk according to the primary tumor’s site. Methods: Subjective Global Assessment was applied to 3008 patients within 48 h of admission to a public university. Subjects were divided into Oncologic Group (n = 576) or Non-Oncologic Group (n = 2432) according to the presence of neoplasms or other diseases respectively. These data were compared by the t-student test and classic chi-square test, with statistical significance set at p < 0.05. Results: The Oncologic Group presented a higher prevalence of weight loss (60.3% vs. 49.3%), quantitative (40.7% vs. 28.5%) and qualitative (16.4% vs. 7.6%) alterations in the food intake pattern, gastrointestinal symptoms and muscle waste (23.2% vs. 13.2%) as compared to the Non-Oncologic Group. Also, there was a higher prevalence of nutritional disturbances in the Oncologic Group, with 49.5% of the subjects moderately (or suspected to be malnourished) and 12.7% severely mal-nourished. Severe malnourishment was mainly observed in patients with head and neck (25%), upper digestive tract (21.9%) and soft tissue and bones (17.9%) tumors. Conclusion: When compared to other hospitalized patients, patients with neoplastic disease were in higher nutritional risk.

关键词： Nutritional Screening Malnutrition Subjective Global Assessment Hospital Setting Neoplasia

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SARS-CoV-2 productively infects primary human immune system cells in vitro and in CoviD-19 patients

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Journal of Molecular Cell Biology 2022年第4期14卷 51-64页

作者： Marjorie C.Pontelli italo A.Castro Ronaldo B.Martins Leonardo La Serra Flavio P.Veras Daniele C.Nascimento Camila M.Silva Ricardo S.Cardoso roberta Rosales Rogério Gomes Thais M.Lima Juliano P.Souza Brenda C.Vitti Diego B.Caetite Mikhael H.F.de Lima Spencer D.Stumpf Cassandra E.Thompson Louis-Marie Bloyet Juliana E Toller-Kawahisa Marcela C.Giannini Leticia P.Bonjorno Marial.F.Lopes Sabrina S.Batah Li Siyuan Rodrigo Luppino-Assad Sergio C.L.Almeida Fabiola R.Oliveira Maira N.Benatti Lorena L.F.Pontes Rodrigo C.Santana Fernando C.Vilar Maria Auxiliadora-Martins Pei-Yong Shi Thiago M.cunha Rodrigo T.Calado JoséC.Alves-Filho Dario S.Zamboni Alexandre T.Fabro Paulo Louzada-Junior Rene D.R.Oliveira Sean P.J.Whelan Fernando Q.cunha Eurico Arruda Virology Research Center Ribeirao Preto Medical SchoolUniversity of Sao Pauloibeirao PretoSao Paulo 14049-900.Brazil Center of Research in Inflammatory Diseases Ribeirao Preto Medical SchoolUniversity of Sao PauloRibeirao PretoSao Paulo 14049-900Brazil Department of Celland Molecular Biology Ribeirao Preto Medical SchoolUniversityof Sao PauloRibeirao PretoSao Paulo 14049-900 Brazil Regional Blood Centerof Ribeirao Preto Ribeirao Preto Medical ScholUniversity of Sao PauloRibeirao PretoSao Paulo 14049-900Brazil Department of Biochemistry&Molecular Biology the University of Texas Medical BranchGalvestonTX7755USA Divisions of Clinical lmmunology Infectious Diseases and Intensive Care UnitRibeirao Preto Medical Schooniversity of Sao PauloRibeirao PretoSao Paulo 14049-900Brazil Department of Pathology Ribeirao Preto Medical Scholniversity of Sao PauloRibeirao PretoSao Paulo 14049-900Brazil Department of Molecular Microbiology.Washington University in St.Louis Saint LouisMO 63110USA

The severe acute respiratory syndrome coronavirus 2(SARS-CovV-2)infection is associated with a hyperinflammatory state and lymphocytopenia,a hallmark that appears as both signature and prognosis of disease severity *** cytokine storm and a sustained inflammatory state are commonly associated with immune cell depletion,it is still unclear whether direct SARS-Cov-2 infection of immune cells could also play a role in this scenario by harboring viral *** found that monocytes,as well as both B and T lymphocytes,were susceptible to SARS-Cov-2 infection in vitro,accumulating double-stranded RNA consistent with viral RNA replication and ultimately leading to expressive T cell *** addition,flow cytometry and immunofluorescence analysis revealed that SARS-Cov-2 was frequently detected in monocytes and B lymphocytes from coronavirus disease 2019(CoVID-19)*** rates of SARS-Cov-2-infected monocytes in peripheral blood mononuclear cells from CoVID-19 patients increased over time from symptom onset,with SARS-CoV-2-positive monocytes,B cells,and CD4+T lymphocytes also detected in postmortem lung *** results indicated that SARS-CoV-2 infection of blood-circulating leukocytes in covID-19 patients might have important implications for disease pathogenesis and progression,immune dysfunction,and virus spread within the host.

关键词： SARS-CoV-2 CoVID-19 lymphocytopenia peripheral blood mononuclear cell(PBMC) lymphocytes monocytes apoptosis

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