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Activation of Defense Response Pathways by OGs and Fig22 Elicitors in Arabidopsis Seedlings

Molecular Plant 2008年第3期1卷 423-445页

作者： Carine Denoux roberta Galletti Nicole Mammarella Suresh Gopalan Danièle Werck Giulia De Lorenzo Simone Ferrari Frederick M. Ausubel Julia Dewdney Department of Genetics Harvard Medical School and Department of Molecular Biology Massachusetts General Hospital 185 Cambridge St Simches 7700Boston MA 02114 USA Institut de Biologie Moleculaire des Plantes CNRS Universite Louis Pasteur. Strasbourg France dipartimento di Biologia Vegetale University di Roma 'La Sapienza' Piazzale Aldo Moro 5 00185 Rome. Italy

We carried out transcriptional profiling analysis in 10-d-old Arabidopsis thaliana seedlings treated with oligogalacturonides （OGs）, oligosaccharides derived from the plant cell wall, or the bacterial flagellin peptide Fig22, general elicitors of the basal defense response in plants. Although detected by different receptors, both OGs and Fig22 trigger a fast and transient response that is both similar and comprehensive, and characterized by activation of early stages of multiple defense signaling pathways, particularly JA-associated processes. However, the response to Fig22 is stronger in both the number of genes differentially expressed and the amplitude of change. The magnitude of induction of individual genes is in both cases dose-dependent, but, even at very high concentrations, OGs do not induce a response that is as comprehensive as that seen with Fig22. While high doses of either microbe-associated molecular pattern （MAMP） elicit a late response that includes activation of senescence processes, SA-dependent secretory pathway genes and PR1 expres- sion are substantially induced only by Fig22. These results suggest a lower threshold for activation of early responses than for sustained or SA-mediated late defenses. Expression patterns of amino-cyclopropane-carboxylate synthase genes also implicate ethylene biosynthesis in regulation of the late innate immune response.

关键词： Fig22 唇形科种子活化作用

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Metastatic Breast Neuroendocrine Cancer in Pregnancy:A Case of an Oncologic Emergency and a Review of Literature

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Maternal-Fetal Medicine 2020年第4期2卷 248-252页

作者： De Luca Caterina Tosto Valentina Badr Dominique A. De Luca Laura Porreca roberta di Renzo Gian Carlo Department of Obstetrics and Gynecology University Hospital Santa Maria della MisericordiaPerugia 06129Italy Department of Obstetrics and Gynecology University Hospital BrugmannUniversitéLibre de BruxellesBrussels 1020Belgium Department of Obstetrics and Gynecology University Hospital ErasmeUniversitéLibre de BruxellesBrussels 1070Belgium Department of Oncology University Hospital Santa Maria della MisericordiaPerugia 06129Italy.

Breast neuroendocrine carcinoma is a rare *** constitutes less than 0.5%of breast malignancies,and is usually diagnosed in older *** occurrence of this type in young patients during pregnancy is extremely *** 2 cases were previously *** were diagnosed at earlier stage with the appearance of a palpable breast ***,we present the case of a young patient at 28 weeks’gestation admitted for severe diffuse back pain and neurologic deficit due to spinal cord compression at the level of C5 vertebra,and nerve root compression at the level of L5 *** the best of our knowledge,this is the first case of oncologic emergency during pregnancy due to a metastatic poorly differentiated breast carcinoma with neuroendocrine differentiation in the absence of a detectable primary focus of malignancy in the *** also discuss the management and the obstetrical outcome of this patient.

关键词： Neoplasm metastasis Neuroendocrine breast carcinoma Oncologic emergency Pregnancy

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350 μm map of the Ophiuchus molecular cloud: core mass function

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Science China(Physics,Mechanics & Astronomy) 2015年第2期58卷 114-124页

作者： ZHANG GuoYin LI di HYDE Ashley K QIAN Lei LYU HuaLei WU ZhongZu College of Science/Department of Physics Guizhou University Key Laboratory of Radio Astronomy Chinese Academy of Sciences National Astronomical Observatories Chinese Academy of Sciences Space Science Institute Department of Astronomy California Institute of Technology Astrophysics Group Imperial College London

Stars are born in dense cores of molecular clouds. The core mass function （CMF）, which is the mass distribution of dense cores, is important for understanding the stellar initial mass function （IMF）. We obtained 350μm dust continuum data using the SHARC-II camera at the Caltech Submillimeter Observatory （CSO） telescope. A 350μm map covering 0.25 deg2 of the Ophiuchus molecular cloud was created by mosaicing 56 separate scans. The CSO telescope had an angular resolution of 9＂, corresponding to 1.2 ×103 AU at the distance of the Ophiuchus molecular cloud （131 pc）. The data was reduced using the Comprehensive Reduction Utility for SHARC-II （CRUSH）. The flux density map was analyzed using the GaussClumps algorithm, within which 75 cores has been identified. We used the Spitzer c2d catalogs to separate the cores into 63 starless cores and 12 protostellar cores. By locating Jeans instabilities, 55 prestellar cores （a subcategory of starless cores） were also identified. The excitation temperatures, which were derived from FCRAO 12CO data, help to improve the accuracy of the masses of the cores. We adopted a monte Carlo approach to analyze the CMF with two types of functional forms; power law and log-normal. The whole and prestellar CMF are both well fitted by a log-normal distribution, with p = -1. 18 ±0.10, σ = 0.58 ± 0.05 and μ= 1.40 ＋ 0.10, σ= 0.50 ＋ 0.05 respectively. This finding suggests that turbulence influences the evolution of the Ophiuchus molecular cloud.

关键词： 1SM molecular clouds Ophiuchus CMF

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Preliminary Considerations About the Transposition of directive 2013/34/EU Into Italian Accounting System

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Journal of Modern Accounting and Auditing 2015年第6期11卷 302-312页

作者： roberta Provasi Claudio Sottoriva Universita degli Studi di Milano Milan Italy Universita Cattolica del Sacro Cuore Milan Italy

With the directive No. 2013/34/EU dated June 26, 2013, the Parliament and the European Council have decreed a new era for the financial statements of companies in the EU member countries. The introduction of the new directive aims to improve the coverage information of the accounting document and to begin a process of simplification of administrative burdens and standards for the preparation and publication of the financial statements. In Italy, the directive must be transposed by July 20, 2015 for which the associations of accountants are evaluating the specific contents of the new rules to make applications for Italian companies. Some of the new rules and above all part of the new structures of the schemes of the financial statements are quite different from the approaches currently in use for which very heated discussions are taking place.

关键词： European directive 2013/34/EU Italian accounting system accounting harmonization

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Cognitive-behavioural therapy for obsessive-compulsive disorder co-occurring with psychosis: Systematic review of evidence

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World Journal of Psychiatry 2016年第4期6卷 449-455页

作者： Antonio Tundo roberta Necci Istituto di Psicopatologia

AIM To review available evidence on the use of cognitive behavioural therapy(CBT) for treating obsessive compulsive disorder co-occurring with *** In this paper we present a detailed and comprehensive review of the current literature focusing on CBT treatment of obsessive compulsive disorder(OCD) co-occurring with schizophrenia or schizoaffective disorder. We identified relevant literature published between 2001 and May 2016 through MEDLINE/PubM ed search using as search string("obsessive compulsive disorders" or "obsessive compulsive symptoms") and("schizophrenia" or "schizoaffective disorder" or "psychosis") and("cognitive behavioural therapy"). Other citations of interest were further identified from references reported in the accessed articles. The search was limited to studies written in English and carried out in adult patients. A total of 9 studies, 8 case reports and 1 case series, were *** The reviewed evidence indicates that CBT is:(1) safe, i.e., does not worsen psychotic symptoms;(2) well accepted, with a discontinuation rate quite similar to that reported for patients with OCD without psychosis comorbidity;(3) effective, with a symptom reduction quite similar to that reported for patients with OCD without psychosis and for SRIs treatment of OCD cooccurring with psychosis; and(4) effective in patients with OCD induced by second-generation antipsychotic as well as in patients with OCD not induced by secondgeneration antipsychotic. Alcohol/substance use disorder comorbidity and OCD onset preceding that of SCH/SA was predictors of poor outcome. These results are derived only by additional studies with adequate sample *** Our results support the use of CBT for OCD in patients with psychosis.

关键词： Obsessive compulsive disorder Obsessive compulsive symptoms Schizophrenia Schizoaffective disorder Cognitive behavioural therapy Secondgeneration antipsychotic Clozapine

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Simulation of EOM-based frequency-chirped laser slowing of MgF radicals

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Frontiers of physics 2022年第4期17卷 173-183页

作者： Kang Yan RuoXi Gu di Wu Jin Wei Yong Xia Jianping Yin State Key Laboratory of Precision Spectroscopy School of Physics and Electronic ScienceEast China Normal UniversityShanghai 200241China NYU-ECNU Institute of Physics at NYU Shanghai Shanghai 200062China Collaborative Innovation Center of Extreme Optics Shanxi UniversityTaiyuan 030006China

Here we propose a scheme to slow MgF molecules by using EOM-based frequency-chirped radiation pressure *** scheme well addresses the need for a rapid chirp rate while light molecules are being laser slowed,whose scattering rate and recoil velocity are *** EOMs are used to compensate the rapidly changing Doppler shifts arised from the movement of molecules,and to cover the hyperfine energy structure of MgF,*** the scattering rate maps calculated from an optical Bloch equation model,individual molecule trajectories are simulated by using a semi-classical three-dimensional monte Carlo *** show how the modulation configuration of EOM and the magnetic field influence the slowing *** study shows that a cryogenic buffer gas-cooled MgF beam source is possible to be slowed down with a number of∼1.4×10^(6)–10^(7),and the final forward speed peaks at∼10 m/s near the capture velocity of a molecular MOT.

关键词： laser cooling of molecule MgF molecule laser slowing dark state type-II transition

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Experimental study on instability mechanism and critical intensity of rainfall of high-steep rock slopes under unsaturated conditions

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International Journal of Mining Science and Technology 2023年第10期33卷 1243-1260页

作者： Xiaoshuang Li Qihang Li Yunmin Wang Wei Liu di Hou Wenbo Zheng Xiong Zhang School of Urban Construction Changzhou UniversityChangzhou 213164China College of Civil Engineering Qilu Institute of TechnologyJinan 250200China Key Laboratory of Rock Mechanics and Geohazards of Zhejiang Province Shaoxing 312000China School of Resources and Safety Engineering Chongqing UniversityChongqing 400044China Sinosteel Maanshan General Institute of Mining Research Co.LTD. Maanshan 243000China Guizhou Survey and Design Research Institute for Water Resources and Hydropower Guiyang 550001China School of Engineering University of Northern British ColumbiaPrince George V2K3V3Canada

Two critical factors,namely intense precipitation and intricate excavation,can trigger rock mass disasters in mining *** this study,an indoor rainfall system was developed to precisely regulate the flow and intensity of precipitation.A large-scale model experiment was conducted on a self-designed physical simulation experiment platform to investigate the failure and instability of high-steep rock slopes under unsaturated *** real-time reproduction of the progressive failure process in high-steep rock slopes enabled the determination of the critical rainfall intensity and revealed the mechanism underlying slope *** results indicated that rainfall may be the primary factor contributing to rock mass instability,while continuous pillar mining exacerbates the extent of rock mass *** critical failure stage of high-steep rock slopes occurs at a rainfall intensity of 40 mm/h,whereas a rainfall exceeding 50 mm can induce critical instability and precipitation reaching up to 60 mm will result in slope *** improved region growing segmentation method(IRGSM)was subsequently employed for image recognition of rock mass deformation in underground *** an error comparison with the simple linear iterative cluster(SLIC)superpixel method and the original region growing segmentation method(ORGSM)showed that the average identification error in the X and Y directions by the method was reduced significantly(1.82%and 1.80%in IRGSM;4.70%and 6.26%in SLIC;9.45%and 12.40%in ORGSM).Ultimately,the relationship between rainfall intensity and failure probability was analyzed using the monte Carlo ***,the stability assessment criteria of rock slope under unsaturated condition were quantitatively and accurately evaluated.

关键词： Open-pit to underground mining Rock slope Rainfall infiltration Excavation unloading Similar physical model Image recognition

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基于相对风险模型的区域生态风险评价

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科学技术与工程 2024年第7期24卷 3020-3033页

作者：朱家兵吴建廷张华崔言辉梁甲迪李西春浪潮软件科技有限公司济南250101 山东省国土空间数据和遥感技术研究院济南250000

部分生态系统在现代社会经济发展过程中遭到了不同程度的破坏,而生态风险评价是对生态系统健康状况最重要的衡量方法之一。以云南省为研究区,选取4类主要风险源,划分5类生境,以生态系统为风险受体,4类生态系统服务为评价终点,采用相对... 详细信息

部分生态系统在现代社会经济发展过程中遭到了不同程度的破坏,而生态风险评价是对生态系统健康状况最重要的衡量方法之一。以云南省为研究区,选取4类主要风险源,划分5类生境,以生态系统为风险受体,4类生态系统服务为评价终点,采用相对风险模型(relative risk model, RRM),分别计算云南省各生境、风险源、评价终点及评价单元的生态风险值,并划分风险等级;利用蒙特卡洛模拟方法进行不确定性分析,并结合评价结果进行风险管理分析。结果表明:云南省生态风险整体状况良好,空间差异较小;昭通市的相对风险等级最高,但结果误差最大;城市生态系统生境受到的风险、人口负荷风险源对生态系统造成的风险、调节服务对生态风险的响应,三者评价结果均为最高;风险源的不确定性对风险结果的影响存在低估现象,且风险演变模拟结果趋向收敛。

关键词：生态风险评价 RRM 生态系统不确定性分析

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A study of beryllium moderator thickness for a fission chamber with fast neutron measurements

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Nuclear Science and Techniques 2017年第9期28卷 51-56页

作者： Wen-di Wang Hong-Rui Cao Jing Cao Guo-Liang Yuan Ze-Jie Yin State Key Laboratory of Particle Detection and Electronics University of Science and Technology of ChinaHefei 230026 China Department of Modern Physics University of Science andTechnology of China Hefei 230026 China Southwestern Institute of Physics Chengdu 610041 China

The detection efficiency of the fission chamber(FC) is very important for studying the neutron flux measurement(NFM) system in ITER. In this article, we mainly focus our attention on the influence of the moderator. With the monte Carlo particle transport simulation tool named Geant4, we make a simulation of FC detection efficiency with different levels of thickness of a beryllium *** manufactured FCs for ITER-NFM systems are then used to test the parameters and performance. The test results agree well with our simulation.

关键词：中子测量慢化剂裂变室厚度 Geant4 铍测量系统模拟工具

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Selective Gold Deposition on a Nanostructured Block Copolymer Film Crystallized by Epitaxy

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Nano Research 2011年第3期4卷 241-248页

作者： Claudio De Rosa Finizia Auriemma Rocco di Girolamo Rossella Aprea Annette Thierry dipartimento di Chimica ＂P. Corradini＂ Universit~t di Napoli ＂Federico II＂ Complesso Monte S. Angelo Via Cintia 80126 Napoli Italy Institut Charles Sadron University de Strasbourg CNRS-UPR 22 B. E 84047 23 rue du Loess 67034 Strasbourg France

An ordered nanostructure formed by epitaxial crystallization of a semicrystalline block copolymer on a substrate has been used as a patterned template for the selective deposition of thermally evaporated gold nanoparticles, resulting in the formation of structure-guiding host nanocomposites in which the ordered distribution of the guest particles is guided by the ordering of the host nanostructured block copolymer matrix. This opens new perspectives in the field of polymeric composites related to the maximum enhancement of effective physical properties and to the numerous possible applications that arise due to the presence of long-range order in the spatial distribution of functional nanoparticles.

关键词： Crystalline block copolymers nanostructures nanocomposites gold deposition

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