检索结果-南通市图书馆

Dengue positivity among blood donors in hyper-endemic region of southern India

Asian Pacific Journal of Tropical Medicine 2023年第4期16卷 190-192页

作者： Mahadevan Ganesan Robert Sudha Ganesan Sucila Thangam Sivathanu Lalitha Virus Research and Diagnostic Laboratory Department of MicrobiologyGovernment Theni Medical CollegeTheniTamil NaduIndia Department of Microbiology Government Theni Medical CollegeTheniTamil NaduIndia

Transfusion-transmitted infections(TTIs)impose meticulous screening protocols in blood banks.Emerging or re-emerging viruses with altered pathogenicity remains debatable whether or not to include those in TTI screening panel.Dengue infection is known to transmit via Aedes aegypti mosquito;however,the route of infection through blood transfusion is recently of greater importance.India with hyper-endemic and endemic dengue regions must guarantee the safety in transfusion-related products.The donor with asymptomatic dengue infection during viremic phase can act as a reservoir for transmission.The acute infection in dengue is ascertained by detecting either nonstructural-1 protein(NS1)or IgM antibody whereas the prevalence of dengue can be monitored by the presence of IgG.

关键词： transfusion reservoir guarantee

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Lesson learned: Retrospective analysis of 'missed out' dengue NS1 positives among IgM negative population

引用

Asian Pacific Journal of Tropical Medicine 2020年第5期13卷 221-226页

作者： Mahadevan Ganesan Robert Sudha Murugesan Amudhan Ganesan Sucila Thangam Department of Microbiology Govt.Theni Medical CollegeTheniTamilnaduIndia

Objective:To determine the proportion of dengue non-structural protein 1(NS1)positives among laboratory confirmed dengue IgM negative patients.Methods:Data for 1732 samples received from January to October 2017 at the Virus Research and Diagnostic Laboratory(VRDL)for dengue diagnosis were downloaded from the National Institute of Epidemiology server.Samples that were previously reported as IgM negative for dengue diagnosis were identified and their NS1 status was determined using ELISA.Thus,'missed out'NS1 positives were correlated with the duration of illness.Furthermore,an epidemic curve for the study period was constructed.The increase in positivity rate within and between the months was compared by McNemar's and Pearson's chi-square test,respectively.Results:The reported IgM-negatives were 813,of which,22.5%(183)were retrospectively positive for NS1 antigen.The addition of NS1 positives revealed by this study has raised the reported positivity across the months that ranged from 8.1%to 29.6%.By analyzing the dengue positives per month and the epidemic curve,the period between January and September,2017 was identified as non-epidemic while the epidemic started from the month of October,2017.Conclusions:Acute dengue infection is widely confirmed by detecting NS1 antigen in serum.Missing out of NS1 positives happen due to shortened window period and such cases act as reservoir for further viral transmission.Hence,this study highly emphasizes performing all three tests for dengue diagnosis that warrants the accurate dengue proportion in India.

关键词： Dengue diagnosis NS1 ELISA IgM negative

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：