原 B 细胞白血病是 B 型急性淋巴细胞白血病(Al.)中最原始的一种亚型,在儿童和成人 Al. 中各占约5%和10%。其原始细胞免疫表型特点为CD19^+胞浆或表面 CD79a^+、CD22^+、CD24^+、CD10^-、胞浆IgM^-和表面 Ig^-。儿童原 B 细胞 Al. 常与...
详细信息
原 B 细胞白血病是 B 型急性淋巴细胞白血病(Al.)中最原始的一种亚型,在儿童和成人 Al. 中各占约5%和10%。其原始细胞免疫表型特点为CD19^+胞浆或表面 CD79a^+、CD22^+、CD24^+、CD10^-、胞浆IgM^-和表面 Ig^-。儿童原 B 细胞 Al. 常与患者年龄<1岁、高白细胞计数、肝脾明显肿大和中枢神经系统浸润等预后不佳的临床指标相关联。
Background During the COVID-19 pandemic,decreased vol.mes of stroke admissions and mechanical.thrombectomy were *** study’s objective was to examine whether subarachnoid haemorrhage(SAH)hospital.sations and ruptured ...
详细信息
Background During the COVID-19 pandemic,decreased vol.mes of stroke admissions and mechanical.thrombectomy were *** study’s objective was to examine whether subarachnoid haemorrhage(SAH)hospital.sations and ruptured aneurysm coil.ng interventions demonstrated simil.r *** We conducted a cross-sectional.retrospective,observational.study across 6 continents,37 countries and 140 comprehensive stroke *** with the diagnosis of SAH,aneurysmal.SAH,ruptured aneurysm coil.ng interventions and COVID-19 were identified by prospective aneurysm databases or by International.Cl.ssification of Diseases,10th Revision,*** 3-month cumul.tive vol.me,monthl. vol.mes for SAH hospital.sations and ruptured aneurysm coil.ng procedures were compared for the period before(1 year and immediatel. before)and during the pandemic,defined as 1 March-31 May *** prior 1-year control.period(1 March-31 May 2019)was obtained to account for seasonal.*** There was a significant decl.ne in SAH hospital.sations,with 2044 admissions in the 3 months immediatel. before and 1585 admissions during the pandemic,representing a rel.tive decl.ne of 22.5%(95%CI−24.3%to−20.7%,pl.sation of ruptured aneurysms decl.ned with 1170-1035 procedures,respectivel.,representing an 11.5%(95%CI−13.5%to−9.8%,p=0.002)rel.tive *** anal.sis was noted for aneurysmal.SAH hospital.sation decl.ne from 834 to 626 hospital.sations,a 24.9%rel.tive decl.ne(95%CI−28.0%to−22.1%,pl.tive increase in ruptured aneurysm coil.ng was noted in l.w coil.ng vol.me hospital. of 41.1%(95%CI 32.3%to 50.6%,p=0.008)despite a decrease in SAH admissions in this *** There was a rel.tive decrease in the vol.me of SAH hospital.sations,aneurysmal.SAH hospital.sations and ruptured aneurysm embol.sations during the COVID-19 *** findings in SAH are consistent with a decrease in other emergencies,such as stroke and myocardial.infarction.
暂无评论