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ITPK1 is an InsP/ADP phosphotransferase that controls phosphate signaling in Arabidopsis

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Molecular Plant 2024年第7期17卷 1151-1157页

作者： Esther Riemer Danye Qiu Debabrata Laha robert K.Harmel Philipp Gaugler Verena Gaugler Michael Frei Mohammad-Reza Hajirezaei Nargis Parvin Laha Lukas Krusenbaum Robin Schneider Adolfo Saiardi Dorothea Fiedler Henning J.Jessen Gabriel Schaaf Ricardo F.H.Giehi 不详

(Molecular Plant 14,1864-1880;November 12021)We identified a mistake made when calculating the absolute concentrations of inositol(pyro)phosphates derived from CE-ESl-MS measurements reported in the originally published version of our *** to a calculation error when determining concentrations per fresh biomass,the absolute values shown in the manuscript are approximately 30-fold lower than they should *** mistake affects Figures 2D,3C,4C,and 7D and Figures S4,S11B,S13,and *** all conclusions made in the article referred to relative differences between genotypes and treatments,they remained unaffected by these mistakes.

关键词： ipt Arabidopsis absolute

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2024美国FTA大奖见证柔印卓越表现

印刷杂志 2024年第4期 22-28页

作者： robert Moran 赵嵩(译) 不详杜邦(中国)研发管理有限公司

本文原文刊登于美国柔印技术协会旗下《Flexo》杂志2024年第5期,详见https://***/;杜邦(中国)集团有限公司经授权翻译为中文版。

关键词： FTA 获奖作品金奖回顾评析

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121份澳大利亚小麦材料抗条锈病鉴定及分子检测

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植物病理学报 2024年

作者：黄洁杨金叶 Davinder Singh Peng Zhang robert F.Park 王保通李强西北农林科技大学植物保护学院作物抗逆与高效生产全国重点实验室 Plant Breeding Institute The University of Sydney

条锈病是世界范围内小麦上的重要病害，培育和种植抗病品种是防治条锈病最经济有效的措施。为明确澳大利亚小麦材料的抗条锈病水平及所含抗条锈病基因，本研究利用8个澳大利亚小麦条锈菌流行小种对121份小麦材料进行了苗期抗性鉴定，同... 详细信息

条锈病是世界范围内小麦上的重要病害，培育和种植抗病品种是防治条锈病最经济有效的措施。为明确澳大利亚小麦材料的抗条锈病水平及所含抗条锈病基因，本研究利用8个澳大利亚小麦条锈菌流行小种对121份小麦材料进行了苗期抗性鉴定，同时应用小麦抗条锈病基因Yr5、Yr9 (1B/1R)、Yr10、Yr15、Yr17及Yr26的特异性分子标记进行了分子检测。结果表明，121份小麦材料中，21份(17.35%)对所有供试条锈菌小种均表现抗病，7份(5.79%)均表现感病，其他材料对一个或多个条锈菌小种表现抗病。分子检测结合抗病性鉴定结果显示，3份(2.48%)可能含有Yr5基因，15份(12.40%)可能含有Yr9,9份(7.44%%)可能含有Yr10,6份(4.96%)可能含有Yr17,19份(15.70%)可能含有Yr26，没有检测到Yr15基因。此外，其中13份材料同时检测到两个或两个以上的抗条锈病基因，还有19份材料可能含有其他已知或未知的抗条锈基因。本研究为121份澳大利亚小麦材料的合理利用和小麦抗病育种提供了科学依据。

关键词：小麦条锈病抗性鉴定抗病基因分子检测

Evaluation of a Wireless Solar Powered Personal Weather Station

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Agricultural Sciences 2024年第1期15卷 36-53页

作者： robert J. Lascano Timothy S. Goebel Dennis C. Gitz III John E. Stout Cropping Systems Research Laboratory Wind Erosion and Water Conservation Research Unit USDA-ARS Lubbock TX USA

We are evaluating dryland cotton production in Martin County, Texas, measuring cotton lint yield per unit of rainfall. Our goal is to collect rainfall data per 250 - 400 ha. Upon selection of a rainfall gauge, we realized that the cost of using, for example, a tipping bucket-type rain gauge would be too expensive and thus searched for an alternative method. We selected an all-in-one commercially available weather station;hereafter, referred to as a Personal Weather Station (PWS) that is both wireless and solar powered. Our objective was to evaluate average measurements of rainfall obtained with the PWS and to compare these to measurements obtained with an automatic weather station (AWS). For this purpose, we installed four PWS deployed within 20 m of the Plant Stress and Water Conservation Meteorological Tower that was used as our AWS, located at USDA-ARS Cropping Systems Research Laboratory, Lubbock, TX. In addition, we measured and compared hourly average values of short-wave irradiance (Rg), air temperature (Tair) and relative humidity (RH), and wind speed (WS), and calculated values of dewpoint temperature (Tdew). This comparison was done over a 242-day period (1 October 2022-31 May 2023) and results indicated that there was no statistical difference in measurements of rainfall between the PWS and AWS. Hourly average values of Rg measured with the PWS and AWS agreed on clear days, but PWS measurements were higher on cloudy days. There was no statistical difference between PWS and AWS hourly average measurements of Tair, RH, and calculated Tdew. Hourly average measurements of Rg and WS were more variable. We concluded that the PWS we selected will provide adequate values of rainfall and other weather variables to meet our goal of evaluating dryland cotton lint yield per unit rainfall.

关键词： Automation Sensors Citizen Weather Station Mesonet Rainfall Weather Variables

Treatment and prevention of epilepsy in onchocerciasis-endemic areas is urgently needed

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Infectious Diseases of Poverty 2024年第1期13卷 85-89页

作者： robert Colebunders Joseph Nelson Siewe Fodjo Olivia Kamoen Luis-Jorge Amaral Amber Hadermann Chiara Trevisan Mark J.Taylor Julia Gauglitz Achim Hoerauf Yasuaki Sato Katja Polman Maria-Gloria Basanez Dan Bhwana Thomson Lakwo Gasim Abd-Elfarag Sebastien D.Pion Global Health Institute University of AntwerpAntwerpBelgium Department of Neurology Heilig Hart ZiekenhuisLierBelgium Department of Public Health Institute of Tropical MedicineAntwerpBelgium Liverpool School of Tropical Medicine LiverpoolUK Department of Computer Science University of AntwerpAntwerpBelgium Institute of Medical Microbiology Immunology and ParasitologyUniversity Hospital BonnBonnGermany German Center for Infection Research(DZIF) Partner Site Bonn-CologneBonnGermany School of Global Humanities and Social Sciences Nagasaki UniversityNagasakiJapan MRC Centre for Global Infectious Disease Analysis and London Centre for Neglected TropicalDisease Research Department of Infectious Disease EpidemiologySchool of Public HealthImperial College LondonLondonUK National Institute for Medical Research TangaTanzania Vector Control Division Ministry of HealthKampalaUganda School of Public Health University of JubaJubaSouth Sudan Access for Humanity JubaSouth Sudan French National Research Institute for Sustainable Development MontpellierFrance

Background There is increasing epidemiological evidence supporting the association between onchocerciasis and seizures, reinforcing the concept of onchocerciasis-associated epilepsy (OAE). The aim of this paper is to provide an update on the new knowledge about OAE and to propose recommendations to the World Health Organization how to address this public health *** text During the 2nd International Workshop on OAE held on 19-21 September, 2023, in Antwerp, Belgium, participants recognised OAE as a substantial yet neglected public health problem, particularly in areas of sub-Saharan Africa where onchocerciasis remains hyperendemic. Evidence from prospective population-based studies suggest that strengthening onchocerciasis elimination efforts leads to a significant reduction of OAE incidence. There is a need to validate an OAE case definition to estimate the burden of disease and identify onchocerciasis-endemic areas requiring intensification of onchocerciasis elimination programmes and integration of epilepsy care. It is expected that raising awareness about OAE will boost the population uptake of ivermectin. The implementation of a community-based epilepsy treatment programme offering free anti-seizure medications (ASMs) has shown high effectiveness in reducing the frequency of seizures and improving the overall quality of life of people with *** To reduce OAE burden, enhanced collaboration between onchocerciasis and mental health programmes at community, national, and international levels is required. Urgent efforts are needed to ensure the uninterrupted provision of free ASMs in onchocerciasis-endemic areas. Furthermore, OAE should be included in the quantification of the onchocerciasis disease burden.

关键词： Onchocerciasis Morbidity Burden of disease Prevention Ivermectin Epilepsy Nodding syndrome Treatment Children Policy

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典型结构功能一体化复合材料的设计与制备技术

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复合材料学报 2024年

作者：蒋民强胡东源董晨昊 PIERCE robert RUDD Chris 刘晓玲益小苏宁波诺丁汉大学理工学院长三角碳纤维及复合材料技术创新中心丹麦技术大学风力与能源系统学院

在碳纤维增强树脂基复合材料轻量化与结构性能持续提高的前提下，同时附加其特定的功能，尤其是在不损失、甚至提升其层间断裂韧性的情况下，不仅可以弥补结构复合材料天然的缺陷，例如树脂基体的电绝缘性，也可以使其满足特定产品的要... 详细信息

在碳纤维增强树脂基复合材料轻量化与结构性能持续提高的前提下，同时附加其特定的功能，尤其是在不损失、甚至提升其层间断裂韧性的情况下，不仅可以弥补结构复合材料天然的缺陷，例如树脂基体的电绝缘性，也可以使其满足特定产品的要求，例如高刚度兼具一定的吸声降噪特性等。显然，对于航空航天这样的尖端应用领域，这种功能附加或结构功能一体化的复合材料技术对航空航天技术的未来发展至关重要。本文介绍了四种具有典型性的结构功能一体化复合材料的设计、制备与性能研究，分别是基于层间功能化插层和基于内织导电纬纱的导电增韧一体化复合材料、以及多级孔碳化棉纤维填充蜂窝/微穿孔面板的夹芯复合材料结构和编织布/无纺纤维毡复合材料片材折叠成型的结构吸声一体化复合材料。前两种材料分别通过在复合材料富树脂的层间插入导电功能化插层和在复合材料内引入贯通整个材料的导电纬纱网络实现了复合材料的导电性能与层间韧性的同步提高，而后两种材料则分别通过多级孔结构的碳化棉纤维材料填充蜂窝/微穿孔面板夹芯技术和编织布/无纺纤维毡复合材料片材的折叠技术实现了良好的吸声性能等，以展示多尺度、多层次结构设计和制备技术在结构复合材料功能化集成和结构功能一体化方面的应用。

关键词：碳纤维复合材料多功能复合材料导电增韧吸声

Three-dimensional analysis of age and sex differences in femoral head asphericity in asymptomatic hips in the United States

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World Journal of Orthopedics 2024年第8期15卷 754-763页

作者： Mahad M Hassan Aliya G Feroe Brenton W Douglass Andrew E Jimenez Benjamin Kuhns Charles F Mitchell robert L Parisien Daniel A Maranho Eduardo N Novais Young-Jo Kim Ata M Kiapour Department of Orthopedic Surgery University of MinnesotaMinneapolisMN 55454United States Department of Orthopedic Surgery TRIA Orthopaedic CenterBloomingtonMN 55122United States Department of Orthopedic Surgery Boston Children’s HospitalBostonMA 02115United States Department of Orthopedic Surgery Mayo ClinicRochesterMN 55901United States Department of Orthopaedics and Rehabilitation Yale School of MedicineNew HavenCT 06510United States Department of Orthopedic Surgery American Hip Institute Research FoundationDes PlainesIL 60018United States Department of Orthopedic Surgery Mount SinaiNew YorkNY 10029United States Department of Biomechanics Medicineand Rehabilitation of the Locomotor SystemRibeirao Preto Medical SchoolUniversity of São PauloRibeirao Preto 14048-900São PauloBrazil

BACKGROUND The sphericity of the femoral head is a metric used to evaluate hip pathologies and is associated with the development of osteoarthritis and femoral-acetabular *** To analyze the three-dimensional asphericity of the femoral head of asymptomatic pediatric *** hypothesized that femoral head asphericity will vary significantly between male and female pediatric hips and increase with age in both *** Computed tomography scans were obtained on 158 children and adolescents from a single institution in the United States(8-18 years;50%male)without hip *** femoral measurements including the femoral head diameter,femoral head volume,residual volume,asphericity index,and local diameter difference were used to evaluate femoral head *** In both sexes,the residual volume increased by age(P13 years)in females,there were no sex-differences in residual volume and aspherity *** were no age-related changes in mean diameter difference in both sexes(P=0.07)with no significant sex-differences across different age groups(P=0.06).In contrast,there were significant increases in local aspherity(maximum diameter difference)across whole surface of the femoral head and all quadrants except the inferior regions in males(P=0.03).There were no sex-differences in maximum diameter difference at any regions and age group(P>0.05).Increased alpha angle was only correlated to increased mean diameter difference across overall surface of the femoral head(P=0.024).CONCLUSION There is a substantial localized asphericity in asymptomatic hips which increases with age *** 2D measured alpha angle can capture overall asphericity of the femoral head,it may not be sensitive enough to represent regional asphericity patterns.

关键词： Hip Femoral head Sphericity Skeletal growth Sex differences

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制药公司探索在太空中制造最赚钱药物

商业周刊（中文版） 2024年第7期 16-17页

作者： robert Langreth 竹西(译) 不详

实验表明,在微重力条件下结晶高价值蛋白质类药物具有优势,可能会产生新的专利。初创公司LambdaVision Inc.有一些宏伟的计划,想为色素性视网膜炎患者开发世界上第一个基于蛋白质的人工视网膜(色素性视网膜炎是一种遗传性致盲疾病)。制... 详细信息

实验表明,在微重力条件下结晶高价值蛋白质类药物具有优势,可能会产生新的专利。初创公司LambdaVision Inc.有一些宏伟的计划,想为色素性视网膜炎患者开发世界上第一个基于蛋白质的人工视网膜(色素性视网膜炎是一种遗传性致盲疾病)。制造视网膜需要在一个聚合物网中沉积200层超薄的光敏蛋白。这些蛋白质层的沉积必须完全均匀,视网膜才能正常工作,而这个过程在地球上很难完成。

关键词：初创公司制药公司微重力条件人工视网膜光敏蛋白

Evaluation of the Living Conditions and Health Perceptions of Waste Electrical and Electronic Equipment Handlers in the Informal Sector in Dakar

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Occupational Diseases and Environmental Medicine 2024年第2期12卷 115-129页

作者： robert Faomowe Foko Awa Ndong Marius Kedote Fatoumata Bah Absa Lam Cheikh Diop Aminata Toure Mathilde Cabral Mamadou Fall Laboratoire de Toxicologie et d’ Hydrologie Facult&#233 de M&#233decine Pharmacie et Odontostomalogie Universit&#233 Cheikh Anta Diop de Dakar Dakar S&#233n&#233gal Unité Mixte de Recherche d&#8217Exploration et de Diagnostic Unit&#233 de Formation et de Recherche des Sciences de la Sant&#233 Universit&#233 Iba Der Thiam de Thi&#232s Thi&#232s S&#233n&#233gal Institut Ré gional de Sant&#233 Publique Universit&#233 d&#8217Abomey-Calavi Ouidah B&#233nin

Electrical and electronic devices are becoming an increasingly important part of our society. In Africa, and in Senegal in particular, the handling and management of electronic and electrical equipment (EEE) that has reached the end of its life is mainly informal. This professional environment is characterized by the disintegration of the sector and the social heterogeneity that can be found there. The objective of this study is to assess the standard of living of electrical and electronic equipment waste handlers in the Dakar region, as well as their perception of their health. A survey was used to obtain information on sociodemographic background, living arrangements, perception of health status, and good practices to be implemented in case of work-related health problems. Life style, perception of general health and health problems were ranged as excellent, very good, good, average and poor. Informal recyclers in the Dakar region lived mainly in rooms and buildings as tenants (49.1%), or in family homes (48.4%) before starting this activity, and 51.2% continue to live in rooms and buildings as tenants compared to 41.4% who still live in a family home. The perception of health status ranged from poor to excellent, and 4.9% believe that they are limited in work due to a disability or health problem. Informal work is a heterogeneous phenomenon that makes research and policymaking particularly complex. There are several external factors within informal WEEE re-cyclers that can cause health problems or functional disability. However, the living conditions and the perception they have of their state of health are contradictory to the working conditions and the social environment to which they belong. A biomedical approach would consolidate these achievements by confirming or invalidating them.

关键词： E-Waste Informal Work Living Arrangements Health Perception Occupational Exposure