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Photometric observations of three high mass X-ray binaries and a search for variations induced by orbital motion

Research in Astronomy and Astrophysics 2011年第8期11卷 947-964页

作者： Gordon E. Sarty Bogumil Pilecki Daniel E. Reichart Kevin M. Ivarsen Joshua B. Haislip Melissa C. Nysewander Aaron P. LaCluyze Helen M. Johnston robert R. Shobbrook Lászl L. Kiss Kinwah Wu Departments of Psychology and Physics University of Saskatchewan9 Campus DriveSaskatoonSaskatchewan S7N 5A5Canada Warsaw University Observatory Al. Ujazdowskie 400-478 WarsawPoland Universidad de Concepcion Departamento de AstronomaCasilla 160-CConcepcionChile Department of Physics and Astronomy University of North Carolina-Chapel HillCB 3255Phillips HallChapel HillNC 27599-3255USA School of Physics A28 University of SydneyNew South Wales 2006Australia Konkoly Observatory H-1525 BudapestP.O. Box 67Hungary Mullard Space Science Laboratory University College LondonHolmbury St. MaryDorkingSurrey RH5 6NTUnited Kingdom

We searched for long period variation in V-band, It-band and RXTE X-ray light curves of the High Mass X-ray Binaries （HMXBs） LS 1698 / RX J1037.5-5647, HD 110432 / 1H 1249-637 and HD 161103 / RX J1744.7-2713 in an attempt to discover orbitally induced variation. Data were obtained primarily from the ASAS database and were supplemented by shorter term observations made with the 24- and 40-inch ANU telescopes and one of the robotic PROMPT telescopes. Fourier periodograms suggested the existence of long period variation in the V-band light curves of all three HMXBs, however folding the data at those periods did not reveal convincing periodic variation. At this point we cannot rule out the existence of long term V-band variation for these three sources and hints of longer term variation may be seen in the higher precision PROMPT data. Long term V-band observations, on the order of several years, taken at a frequency of at least once per week and with a precision of 0.01 mag, therefore still have a chance of revealing long term variation in these three HMXBs.

关键词： accretion -- stars: Be stars -- stars: neutron stars -- stars: individual LS 1698 HD 110432 HD 161103 -- X-rays: binaries

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Technical and conceptual considerations forusing animated stimuli in studies of animalbehavior

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Current Zoology 2017年第1期63卷 5-19页

作者： Laura CHOUINARD-THULY Stefanie GIERSZEWSKI Gil G. ROSENTHAL Simon M. READER Guillaume RIEUCAU Kevin L. Woo robert GERLAI Cynthia TEDORE Spencer J. INGLEY John R. STOWERS Joachim G.FROMMENI Francine L. DOLINS Klaudia WITTE Department of Biologv McGill University 1205 Docteur Penfield Montreal Quebec Canada H3A 1B1 Research Group of Ecology and Behavioral Biology Institute of Biology University of Siegen Adolf-Reichwein Str. 2 Siegen 57068 Germany Ecology & Evolutionary Biology Texas A&M University 3258 TAMU College Station TX 77843 USA Centro de Investigaciones Cientfficas de las Huastecas "Aguazarca" Calnali Hidalgo Mexico Departmentof Biological Sciences Florida International University 3000 Northeast 151 Street North Miami FL 33181 USA SUNY Empire State College Metropolitan Center 325 Hudson Street New York NY 10013-1005 USA Departmentof Psychology University of Toronto Mississauga 3359 Mississauga Road Mississauga Ontario Canada L5L 1C6 Lund Vision Group Department of Biology Lund University SSIvegatan 35 Lund 22362 Sweden Department of Biology University of North Carolina at Chapel Hill CB#3280 Coker Hall Chapel Hill NC 27599 USA Research Institute of Molecular Pathology IMP Vienna Biocenter VBC Dr. Bohr-Gasse 7 Vienna 1030 Austria loopbiogmbh Hauptstrasse 93 Kritzendorf 3420 Austria Department of Behavioural Ecology Institute of Ecology and Evolution University of Bern Wohlenstrasse 50a Hinterkappelen 3032 Switzerland Department of Behavioral Sciences University of Michigan-Dearborn 4901 Evergreen Road Dearborn MI 48128 USA

Rapid technical advances in the field of computeropened new avenues in animal behavior *** （CA） and virtual reality （VR） haveAnimated stimuli are powerful tools as theyoffer standardization, repeatability, and complete control over the stimulus presented, thereby＂reducing＂ and ＂replacing＂ the animals used, and ＂refining＂ the experimental design in line withthe 3Rs. However, appropriate use of these technologies raises conceptual and technical *** this review, we offer guidelines for common technical and conceptual considerations related tothe use of animated stimuli in animal behavior research. Following the steps required to create ananimated stimulus, we discuss （I） the creation, （11） the presentation, and （111） the validation of CAsand VRs. Although our review is geared toward computer-graphically designed stimuli, consider-ations on presentation and validation also apply to video playbacks. CA and VR allow both new be-havioral questions to be addressed and existing questions to be addressed in new ways, thus weexpect a rich future for these methods in both ultimate and proximate studies of animal behavior.

关键词： animal behavior, animated stimulus, computer animation, experimental design, virtual reality, visual communication.

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Comparison of Two Dose-response Relationship of Noise Exposure Evaluation Results with High Frequency Hearing Loss

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Chinese Medical Journal 2015年第6期128卷 816-821页

作者： Hua Zhang Nan Li Qiu-Ling Yang Wei Qiu Liang-Liang Zhu Li-Yuan Tao robert I Davis Nicholas Heyer Yi-Ming Zhao Research Center of Clinical Epidemiology Peking University Third Hospital Beijing 100191 China Dongfeng Institution of Occupational Disease Prevention Shi ~an Hubei 442001 China Auditory Research Laboratory State University of New York at Plattsburgh 107 Beaumont Hall Plattsburgh New York 12901 USA Battelle Centers for Public Health Research and Evaluation Seattle WA USA

Background:Complex noise and its relation to hearing loss are difficult to measure and *** complex noise measurement,individual exposure results may not accurately represent lifetime noise ***,the mean LAeq,8 h values of individuals in the same workgroup were also used to represent LAeq,8h in our *** study aimed to explore whether the mean exposure levels of workers in the same workgroup represented real noise exposure better than individual exposure levels ***:A cross-sectional study was conducted to establish a model for cumulative noise exposure (CNE) and hearing loss in 205 occupational noise-exposed workers who were recruited from two large automobile manufacturers in *** used a personal noise dosimeter and a questionnaire to determine the workers' occupational noise exposure levels and exposure times,respectively.A qualified audiologist used standardized audiometric procedures to assess hearing acuity after at least 16 h of noise ***:We observed that 88.3％ of workers were exposed to more than 85 dB(A) of occupational noise (mean:89.3 ± 4.2 dB(A)).The personal CNE (CNEp) and workgroup CNE (CNEg) were 100.5 ± 4.7 dB(A) and 100.5 ± 2.9 dB(A),*** the binary logistic regression analysis,we established a regression model with high-frequency hearing loss as the dependent variable and CNE as the independent *** Wald value was 5.014 with CNEp as the independent variable and 8.653 with CNEg as the independent ***,we found that the figure for CNEg was more similar to the stationary noise reference than CNEp *** CNEg model was better than the CNEp *** this circumstance,we can measure some subjects instead of the whole workgroup and save ***:In a complex noise environment,the measurements of average noise exposure level of the workgroup can improve the accuracy and save manpower.

关键词： Complex Noise Cumulative Noise Exposure Dose-response Relationship Noise Exposure Evaluation Workgroup

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冲刷作用下砂土地层中桩的侧向力学性质分析

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南方能源建设 2018年第2期5卷 24-36页

作者：林城韩杰 Caroline BENNETT robert PARSONS 加拿大维多利亚大学土木工程系美国堪萨斯大学土木环境与建筑系

[目的]冲刷是在水流以及波浪作用下土体流失的一个过程,它通常发生在桥梁、港口码头、以及海岸平台等结构的基础周围,造成基础的承载力下降,危及上部结构的安全。目前在分析桩的侧向力学行为时,只考虑了冲刷深度对桩的侧向承载力的影响... 详细信息

[目的]冲刷是在水流以及波浪作用下土体流失的一个过程,它通常发生在桥梁、港口码头、以及海岸平台等结构的基础周围,造成基础的承载力下降,危及上部结构的安全。目前在分析桩的侧向力学行为时,只考虑了冲刷深度对桩的侧向承载力的影响,而忽略了冲刷形成的冲刷孔的影响。事实上,冲刷孔的几何形状不仅包括冲刷深度、还包括了冲刷孔的宽度以及冲刷孔的坡度。目前,工程设计中广泛采用的侧向桩分析方法,即p-y曲线方法无法考虑冲刷孔三维几何形状对桩的侧向力学性质的影响。[方法]针对这个问题,文章提出了一种修正的p-y曲线方法以用于分析砂土地层中桩在冲刷作用下的侧向力学响应。[结果]该方法改进了基于锲形体破坏模型的Reese p-y曲线法,从而能考虑冲刷孔三维几何形状的影响。将计算得到的结果与三维有限差分数值分析的结果进行了比较,验证该修正方法的可靠性。[结论]计算结果表明:在冲刷孔的几何形状参数里,冲刷深度对桩的侧向力学性质的影响最大,其次是冲刷孔的宽度与坡度。忽略冲刷孔几何形状的影响,桩在地面位置的侧向位移会增加49%~68%。

关键词：侧向位移侧向力数值方法桩

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谁是杀人凶手？

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英语学习 2009年第10期 38-41页

作者： robert Barr 俞慕迟(选注)

出于泄愤，同事向他开了一枪，他的性命危在旦夕；而最终，他却死在了鹣鲽情深的妻子手里，这又是为什么呢？

关键词：英语阅读教学阅读材料课外阅读

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Identification of new genetic risk factors for prostate cancer

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Asian Journal of Andrology 2009年第1期11卷 49-55页

作者： Michelle Guy Zsofia Kote-Jarai Graham G. Giles Ali Amin Al Olama Sarah K. Jugurnauth Shani Mulholland Daniel A. Leongamomlert Stephen M. Edwards Jonathan Morrison Helen I. Field Melissa C. Southey Gianluca Severi Jenny L. Donovan Freddie C. Hamdy David R Dearnaley Kenneth R. Muir Charmaine Smith Melisa Bagnato Audrey T. Ardern-Jones Amanda L. hall Lynne T. O＇Brien Beatrice N. Gehr-Swain Rosemary A. Wilkinson Angela Cox Sarah Lewis Paul M. Brown Sameer G. Jhavar Malgorzata Tymrakiewicz Artitaya Lophatananon Sarah L. Bryant The UK Genetic Prostate Cancer Study Collaborators British Association of Urological Surgeons＇ Section of Oncology and The UK ProtecT Study Collaborators Alan Horwich robert A. Huddart Vincent S. Khoo Christopher C. Parker Christopher J. Woodhouse Alan Thompson Tim Christmas Chris Ogden Cyril Fisher Charles Jameson Colin S. Cooper Dallas R. English John L. Hopper David E. Neal Douglas E Easton Rosalind A. Eeles Section of Cancer Genetics The Institute of Cancer Research Sutton Surrey SM2 5NG UK Cancer Epidemiology Centre The Cancer Council Victoria Carlton VIC 3053 Australia Centre for Molecular Environmental Genetic and Analytic Epidemiology The University of Melbourne Carlton VIC 3053 Australia Cancer Research UK Genetic Epidemiology Unit University of Cambridge Strangeways Laboratory Worts Causeway Cambridge CB1 8RN UK Department of Oncology University of Cambridge Strangeways Laboratory Worts Causeway Cambridge CB1 8RN UK Genetic Epidemiology Laboratory Department of Pathology The University of Melbourne Parkville VIC 3052 Australia Department of Social Medicine University of Bristol Bristol BS8 2PR UK Academic Urology Unit University of Sheffield Sheffield SIO 2JF UK The Royal Marsden NHS Foundation Trust Sutton Surrey SM2 5PT and London SW3 6JJ UK University of Nottingham Medical School Queens Medical Centre Nottingham NG7 2UH UK Institute for Cancer Studies University of Sheffield Sheffield SIO 2RX UK Surgical Oncology （Uro-Oncology S4） Departments of Oncology and Surgery University of Cambridge Addenbrooke＇s Hospital Cambridge CB2 2QQ UK A full list of authors is provided in the Supplementary Note online Ka Shing Centre Cambridge CB2 ORE UK Cancer Research UK Cambridge Research Institute Li Ka Shing Centre Cambridge CB2 ORE UK.

There is evidence that a substantial part of genetic predisposition to prostate cancer （PCa） may be due to lower penetrance genes which are found by genome-wide association studies. We have recently conducted such a study and seven new regions of the genome linked to PCa risk have been identified. Three of these loci contain candidate susceptibility genes： MSMB, LMTK2 and KLK2/3. The MSMB and KLK2/3 genes may be useful for PCa screening, and the LMTK2 gene might provide a potential therapeutic target. Together with results from other groups, there are now 23 germline genetic variants which have been reported. These results have the potential to be developed into a genetic test. However, we consider that marketing of tests to the public is premature, as PCa risk can not be evaluated fully at this stage and the appropriate screening protocols need to be developed. Follow-up validation studies, as well as studies to explore the psychological implications of genetic profile testing, will be vital prior to roll out into healthcare.

关键词： prostate cancer genetics susceptibility loci SNPs relative risks

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Modified Green Tea Polyphenols, EGCG-S and LTP, Inhibit Endospore in Three <i>Bacillus</i>spp.

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Advances in Microbiology 2017年第3期7卷 175-187页

作者： Bushra Ali Lee H. Lee Nozrin Laskar Nadia Shaikh Hassan Tahir Stephen D. Hsu robert Newby Jr. Jonathan Valsechi-Diaz Tinchun Chu Department of Biology Montclair State University Montclair NJ USA Department of Oral Biology Augusta University Augusta GA USA Department of Biological Sciences Seton Hall University South Orange NJ USA

Endospores have the ability to withstand extreme temperature, desiccation, ultraviolet radiation and chemicals which make them a threat to the food and healthcare industry. Green tea polyphenols (GTP), contain anti-microbial and anti-spore properties but not stable. In this study, two modified lipophilic green tea polyphenols, epigallocatechin-3-gallate-sterate (EGCG-S) and crude lipophilic green tea polyphenols (LTP), were used to compare their anti-spore effect with EGCG and crude GTP. Purified endospores from Bacillus cereus (B. cereus), B. megaterium and B. subtilis were treated with 1% or 5% of four tea polyphenols. Log reduction showed colony forming units (CFU) reduced significantly in all treated samples, ranging from 1.27 to 4.31 with no survivals (CFU = 0) in four samples (P < 0.05). Average percentage of inhibition for these poly-phenols treatment ranged from 91.68% to 100%. The EGCG-S and LTP have equal or better anti-spore activities compared with EGCG and GTP. EGCG-S and LTP were further used to carry out time course study on B. cereus. The results indicated that 15 min of treatment of 1% and 5% LTP and EGCG-S are able to inhibit 98.7% to 100% of germination. Transmission and scanning electron microscopy studies showed that EGCG-S caused surface disruption and damaged spores structural integrity. EGCG-S and LTP are stable anti-spore agents may aid in preventing food and beverage spoilage caused by spore-forming bacteria as well as preventing contamination in the medical industry.

关键词： Bacterial Spores Antimicrobials Bacillus Germination Biocontrol

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The Role of Synthetic Biology in Atmospheric Greenhouse Gas Reduction: Prospects and Challenges

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BioDesign Research 2020年第1期2020卷 1-8页

作者： Charles DeLisi Aristides Patrinos Michael MacCracken Dan Drell George Annas Adam Arkin George Church robert Cook-Deegan Henry Jacoby Mary Lidstrom Jerry Melillo Ron Milo Keith Paustian John Reilly Richard J.roberts Daniel Segrè Susan Solomon Dominic Woolf Stan D.Wullschleger Xiaohan Yang Department of Biomedical Engineering and Program in Bioinformatics College of EngineeringBoston UniversityBoston MA 02215USA The NOVIM Group Kohn HallUC Santa BarbaraCA 93106USA Climate Institute WashingtonDCUSA Department of Energy WashingtonDCUSA Center for Health Law Ethics&Human Rights at the Boston University School of Public HealthSchool of MedicineBoston UniversityUSA Department of Bioengineering University of CaliforniaBerkeley CAUSA Department of Genetics Harvard Medical SchoolCambridge MAUSA School for the Future of Innovation in Society Arizona State UniversityBarrett&O’Connor Washington Center1800 I StreetNWWashingtonDC 20006USA Sloan School of Management MITCambridge MAUSA Department of Chemical Engineering University of WashingtonSeattle WashingtonUSA The Ecosystems Center of the Marine Biological Laboratory in Woods Hole MAUSA Department of Plant and Environmental Sciences Weizmann Institute of ScienceRehovotIsrael Department of Soil and Crop Sciences Colorado State UniversityFort Collins CO 80523USA MIT Joint Program on the Science and Policy of Global Change MITCambridge MAUSA New England Biolabs Beverly MAUSA Department of Biology and Program in Bioinformatics Boston UniversityBoston MA 02215USA Department of Earth Atmospheric and Planetary SciencesMITCambridge MAUSA Soil and Crop Sciences Section School of Integrated Plant SciencesCornell UniversityIthaca NYUSA Environmental Sciences Division Oak Ridge National LaboratoryOak Ridge TNUSA Biosciences Division Oak Ridge National LaboratoryOak RidgeTNUSA

The long atmospheric residence time of CO2 creates an urgent need to add atmospheric carbon drawdown to CO2 regulatory *** and systems biology(SSB),which enables manipulation of cellular phenotypes,offers a powerful approach to amplifying and adding new possibilities to current land management practices aimed at reducing atmospheric *** participants(in attendance:Christina Agapakis,George Annas,Adam Arkin,George Church,robert Cook-Deegan,Charles DeLisi,Dan Drell,Sheldon Glashow,Steve Hamburg,Henry Jacoby,Henry Kelly,Mark Kon,Todd Kuiken,Mary Lidstrom,Mike MacCracken,June Medford,Jerry Melillo,Ron Milo,Pilar Ossorio,Ari Patrinos,Keith Paustian,Kristala Jones Prather,Kent Redford,David Resnik,John Reilly,Richard ***,Daniel Segre,Susan Solomon,Elizabeth Strychalski,Chris Voigt,Dominic Woolf,Stan Wullschleger,and Xiaohan Yang)identified a range of possibilities by which SSB might help reduce greenhouse gas concentrations and which might also contribute to environmental sustainability and *** include,among other possibilities,engineering plants to convert CO2 produced by respiration into a stable carbonate,designing plants with an increased root-to-shoot ratio,and creating plants with the ability to self-fertilize.A number of serious ecological and societal challenges must,however,be confronted and resolved before any such application can be fully assessed,realized,and deployed.

关键词： Synthetic roberts enable

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考虑实际日粮因素以优化生长肥育猪养殖利润

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饲料工业 2020年第8期41卷 59-64页

作者： Mike D.Tokach Henrique S.Cemin Joel M.DeRouchey robert D.Goodband Jason C.Woodworth Steve S.Dritz 246 Weber hall 1424 Claflin RoadManhattanKS 66506

在猪的生产过程中,75%~80%的饲料用于生长育肥期。因此,育肥阶段对养猪生产者而言具有重要的经济影响。本文通过研究能量水平、氨基酸比例、钙磷含量及其比例以及维生素、微量元素、盐以及包括添加剂在内的其他养分的水平,以优化生长育... 详细信息

在猪的生产过程中,75%~80%的饲料用于生长育肥期。因此,育肥阶段对养猪生产者而言具有重要的经济影响。本文通过研究能量水平、氨基酸比例、钙磷含量及其比例以及维生素、微量元素、盐以及包括添加剂在内的其他养分的水平,以优化生长育肥猪养殖利润。

关键词：生长育肥猪能量氨基酸矿物质维生素添加剂

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Research and developments of laser assisted methods for translation into clinical application

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Frontiers of Optoelectronics 2017年第3期10卷 239-254页

作者： Ronald SROKA Nikolas DOMINIK Max EISEL Anna ESIPOVA Christian FREYMULLER Christian HECKL Georg HENNIG Christian HOMANN Nicolas HOEHNE robert KAMMERER Thomas KELLERER Alexander LANG Niklas MARKWARDT Heike POHLA Thomas PONGRATZ Claus-Georg SCHMEDT Herbert STEPP Stephan STROBL Keerthanan ULAGANATHAN Wolfgang ZIMMERMANN Adrian RUEHM Laser-Forschungslabor LIFE-Center Hospital of University Ludwig-Maximilians University Munich Munich Germany Department of Urology Hospital of University Ludwig-Maximilians University Munich Munich Germany Department of Vascular Surgery Diakonie Klinikum Schwaibisch Hall Germany Labor fur Tumorimmunologie LIFE-Center Hospital of University Ludwig-Maximilians University Munich Munich Germany Friedrich-Loeftter-Institute Federal Research Institute for Animal-Health Greifswald- Insel Riems Germany

Biophotonics and laser medicine are very dynamic and continuously increasing fields ecologically as well as economically. Direct communication with medical doctors is necessary to identify specific requests and unmet needs. Information on innovative, new or renewed techniques is necessary to design medical devices for introduction into clinical application and finally to become established after positive clinical trials as well as medical approval. The long-term endurance in developing light based innovative clinical concepts and devices are described based on the Munich experience. Fluorescence technologies for laboratory medicine to improve non- invasive diagnosis or for online monitoring are described according with new approaches in improving photody- namic therapeutic aspects related to immunology. Regard- ing clinically related thermal laser applications, the introduction of new laser wavelengths and laser parameters showed potential in the treatment of varicose veins as well as in lithotripsy. Such directly linked research and development are possible when researchers and medical doctors perform their daily work in immediate vicinity, thus have the possibility to share their ideas in meetings by day.

关键词： translational biophotonics thermal laser appli-cation fluorescence diagnosis on-line monitoring litho-tripsy phlebology photodynamic therapy (PDT),laboratory medicine

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