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Method for rapid on-site identification of VOCs

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Journal of environmental Sciences 2009年第7期21卷 1005-1008页

作者： Justin D Fair William F Bailey robert A Felty Amy e Gifford Benjamin Shultes Leslie H Volles Department of Chemistry University of Connecticut Storrs Connecticut 06269-3060 USA. INFICON Inc. 2 Technology Place East Syracuse New York 13057 USA

Rapid on-site identification of volatile organic compounds （VOCs） in ambient air is an important first step in remediation efforts. This study describes modification of a commercially available, portable GC/MS system and development of an analysis protocol for rapid （〈 3 min） sampling and identification of VOCs typically found at contaminated sites at the low ppbv level.

关键词： field analysis gas chromatograph mass spectrometer toxic industrial chemicals thermal desorption

Association between exposure to Metals during Pregnancy,Childhood Gut Microbiome,and Risk of Intestinal Inflammation in Late Childhood

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environment & Health 2024年第10期2卷 739-749页

作者： Vishal Midya Manasi Agrawal Jamil M.Lane Chris Gennings Leonid Tarassishin Libni A.Torres-Olascoaga Joseph eggers Jill K.Gregory Mellissa Picker Inga Peter Jeremiah J.Faith Manish Arora Martha M.Tellez-Rojo robert O.Wright Jean-Frederic Colombel Shoshannah eggers Department of environmental Medicine and Climate Science Icahn School of Medicine at Mount SinaiNew York 10029-6574New YorkUnited States Division of Gastroenterology Icahn School of Medicine at Mount SinaiNew York 10029-6574New YorkUnited States Center for Molecular Prediction of Inflammatory Bowel Disease(PReDICT) Department of Clinical MedicineAalborg UniversityCopenhagen 9220Denmark Department of Genetics and Genomic Sciences Icahn School of MedicineNew York 10029-6574New YorkUnited States Center for Research on Nutrition and Health National Institute of Public HealthCuernavaca 62508Mexico Department of Immunology and Immunotherapy Icahn School of Medicine at Mount SinaiNew York 10029-6574New YorkUnited States Department of epidemiology University of Iowa College of Public HealthIowa City 52242 IowaUnited States Instructional Technology Group Icahn School of Medicine at Mount SinaiNew York 10029-6574New YorkUnited States

Alterations to the gut microbiome and exposure to metals during pregnancy have been suggested to impact inflammatory bowel ***,how prenatal exposure to metals eventually results in long-term effects on the gut microbiome,leading to subclinical intestinal inflammation,particularly during late childhood,has not been *** is also unknown whether such an interactive effect drives a specific subgroup of children toward elevated susceptibility to intestinal *** used an amalgamation of machine-learning techniques with a regression-based framework to explore if children with distinct sets of gut microbes and certain patterns of exposure to metals during pregnancy(metal−microbial clique signature)had a higher likelihood of intestinal inflammation,measured based on fecal calprotectin(FC)in late *** obtained samples from a well-characterized longitudinal birth cohort from Mexico City(n=108),*** the second and third trimesters of pregnancy,11 metals were measured in whole *** microbial abundances and FC were measured in stool samples from children 9−11 years of *** FC was defined as having FC above 100μg/g of *** identified subgroups of children in whom microbial and metal−microbial clique signatures were associated with elevated FC(false discovery rate(FDR)e found two metal−microbial clique signatures significantly associated with elevated FC:(1)low cesium(Cs)and copper(Cu)in the third trimester and low relative abundance of eubacterium ventriosum(OR[95%CI]:10.27[3.57,29.52],FDRe third trimester and high relative abundances of Roseburia inulinivorans and Ruminococcus torques(OR[95%CI]:7.21[1.81,28.77],FDRexploratory study demonstrates that children with specific gut microbes and specific exposure patterns to metals during pregnancy may have higher fecal calprotectin levels in late childhood,denoting an elevated risk of intestinal inflammation.

关键词： exposome metals machine learning microbiome environmental epidemiology intestinal inflammation

Functional magnetic resonance imaging in an animal model of pancreatic cancer

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World Journal of Gastroenterology 2010年第26期16卷 3292-3298页

作者： robert J Lewandowski Aaron C eifler David J Bentrem Johnathan C Chung Gayle e Woloschak robert Ryu Riad Salem Andrew C Larson Reed A Omary Department of Radiology Northwestern University Feinberg School of Medicine Chicago IL 60611 United States Department of Surgical Oncology Northwestern University Feinberg School of Medicine Chicago IL 60611 United States Department of Radiation Oncology Northwestern University Feinberg School of Medicine Chicago IL 60611 United States

AIM: To test the hypotheses that diffusion weighed (DW)and transcatheter intraarterial perfusion (TRIP)magnetic resonance imaging (MRI) can each be used to assess regional differences in tumor function in an animal pancreatic cancer ***: VX2 tumors were implanted in pancreata of 6 rabbits. MRI and digital subtraction angiography (DSA) were performed 3 wk following implantation. With a 2-French catheter secured in the rabbit's gastroduodenal artery, each rabbit was transferred to an adjacent 1.5T MRI scanner. DWand TRIP-MRI were performed to determine if necrotic tumor core could be differentiated from viable tumor periphery. For each, we compared mean differences between tumor core/ periphery using a 2-tailed paired t-test (α = 0.05). Imaging was correlated with histopathology. ReSULTS: Tumors were successfully grown in all rabbits, confirmed by necropsy. On DW-MRI, mean apparent diffusion coeffi cient (ADC) value was higher in necrotic tumor core (2.1 ± 0.3 mm2/s) than in viable tumor periphery (1.4 ± 0.5 mm2/s) (P ean perfusion values was higher in tumor periphery (110 ± 47 relative units) than in tumor core (66 ± 31 relative units) (P e used to differentiate necrotic from viable tumor cells in an animal pancreatic cancer model using ADC (DW-MRI) and perfusion (TRIP-MRI) values.

关键词： Animal model Functional magnetic resonance imaging Pancreatic cancer

The liberatory thought of Martin Luther King Jr.

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The liberatory thought of Martin Luther King Jr.

P-Lite: A study of parallel coordinate plot literacy

作者： (1952-)Birt robert e.

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Visual Informatics 2022年第3期6卷 81-99页

作者： elif e.Firat Alena Denisova Max L.Wilson robert S.Laramee School of Computer Science University of NottinghamUK Department of Computer Science University of YorkUK

Visualization literacy,the ability to interpret and comprehend visual designs,is recognized as an essential skill by the visualization *** identify and investigate barriers to comprehending parallel coordinates plots(PCPs),one of the advanced graphical representations for the display of multivariate and high-dimensional *** develop a parallel coordinates literacy test with diverse images generated using popular PCP software *** test improves PCP literacy and evaluates the user’s literacy *** introduce an interactive educational tool that assists the teaching and learning of parallel coordinates by offering a more active learning *** this pedagogical tool,we aim to advance novice users’parallel coordinates literacy *** on the hypothesis that an interactive tool that links traditional Cartesian Coordinates with PCPs interactively will enhance PCP literacy further than static slides,we compare the learning experience using traditional slides with our novel software tool and investigate the efficiency of the educational software with an online,crowdsourced ***-study results show that our pedagogical tool positively impacts a user’s PCP comprehension.

关键词： Human-centered computing Visualization systems and tool empirical studies in visualization

elucidation of the MicroRNA Transcriptome in Western Corn Rootworm Reveals Its Dynamic and evolutionary Complexity

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Genomics, Proteomics & Bioinformatics 2021年第5期19卷 800-814页

作者： Xiaozeng Yang elane Fishilevich Marcelo A.German Premchand Gandra robert e.Mcewan André Billion eileen Knorr Andreas Vilcinskas Kenneth e.Narva Beijing Agro-biotechnology Research Center Beijing Academy of Agriculture and Forestry SciencesBeijing 100097China Corteva Agriscience Agriculture Division of DowDuPontIndianapolisIN 46268USA University of Nebraska-Lincoln Department of EntomologyLincolnNE 68583USA Fraunhofer Institute for Molecular Biology and Applied ecology Department of BioresourcesGiessen 35394Germany

Diabrotica virgifera virgifera(western corn rootworm,WCR)is one of the most destructive agricultural insect pests in North *** is highly adaptive to environmental stimuli and crop protection ***,little is known about the underlying genetic basis of WCR behavior and *** specifically,the involvement of small RNAs(s RNAs),especially micro RNAs(mi RNAs),a class of endogenous small non-coding RNAs that regulate various biological processes,has not been examined,and the datasets of putative s RNA sequences have not previously been generated for *** achieve a comprehensive collection of s RNA transcriptomes in WCR,we constructed,sequenced,and analyzed s RNA libraries from different life stages of WCR and northern corn rootworm(NCR),and identified 101 conserved precursor mi RNAs(pre-mi RNAs)in WCR and other *** also identified 277 corn rootworm specific pre-mi *** analyses of s RNA populations in WCR revealed that its s RNA transcriptome,which includes PIWI-interacting RNAs(pi RNAs)and mi RNAs,undergoes a dynamic change throughout insect *** analysis of mi RNA datasets from model species reveals that a large pool of species-specific mi RNAs exists in corn rootworm;these are potentially evolutionarily *** of WCR mi RNA clusters to other insect species highlight conserved mi RNA-regulated processes that are common to *** Analysis of RNA ends(PARe)also uncovered potential mi RNA-guided cleavage sites in ***,this study provides a new resource for studying the s RNA transcriptome and mi RNA-mediated gene regulation in WCR and other Coleopteran insects.

关键词： Western corn rootworm Small RNA MicroRNA Parallel Analysis of RNA ends PIWI-interacting RNA

Low temperature microwave-assisted vs conventional pyrolysis of various biomass feedstocks

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Journal of Natural Gas Chemistry 2012年第3期21卷 270-274页

作者： Peter Shuttleworth Vitaliy Budarin Mark Gronnow James H.clark Rafael Luque Green Chemistry Centre of excellence University of YorkHeslingtonYO10 5DD YorkUK Departamento de Química Orgnica Universidad de CórdobaCampus de Excelencia Agroalimentario ceiA3Edif icio Marie Curie(C-3)Ctra Nnal IVKm 396E-14014CórdobaSpain

A comparison between conventional pyrolysis and a novel developed low-temperature microwave-assisted pyrolysis methodology has been performed for the valorisation of a range of biomass feedstocks including waste residues. Microwave pyrolysis was found to efficiently deliver comparable evolution of bio-gases in the system as compared with conventional pyrolysis at significantly reduced temperatures （120-180 ℃vs 250-400 ℃）. The gas obtained from microwave-assisted pyrolysis was found to contain CO2, CH4 and CO as major components as well

关键词： microwave-assisted pyrolysis biomass valorisation gas production

Recent Ventures in Interdisciplinary Arctic Research:The ARCPATH Project

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Advances in Atmospheric Sciences 2024年第8期41卷 1559-1568页

作者： Astrid e.J.OGILVIe Leslie A.KING Noel KeeNLYSIDe François COUNILLON Brynhildur DAVIÐSDÓTTIR Níels eINARSSON Sergey GULeV Ke FAN Torben KOeNIGK James R.MCGOODWIN Marianne H.RASMUSSON Shuting YANG Institute of Arctic and Alpine Research(INSTAAR) University of ColoradoBoulder CO 80303USA Stefansson Arctic Institute AkureyriÍS-600Iceland Royal Roads University BC V9B 5Y2Canada University of Bergen Bergen N-5007Norway Nansen environmental and Remote Sensing Centre Bergen N-5007Norway University of Iceland Reykjavík 102Iceland Shirshov Institute of Oceanology Moscow 117218Russia Moscow State University Moscow 11991Russia Chinese Academy of Sciences Beijing 100045China Swedish Meteorological and Hydrological Institute SE-60176 NorrköpingSweden Danish Meteorological Institute CopenhagenØ2100Denmark Obukhov Institute of Atmospheric Physics RAS119017MoscowRussia

This paper celebrates Professor Yongqi GAO's significant achievement in the field of interdisciplinary studies within the context of his final research project Arctic Climate Predictions: Pathways to Resilient Sustainable Societies-ARCPATH(https://***/en/projects/finished-projects/arcpath). The disciplines represented in the project are related to climatology, anthropology, marine biology, economics, and the broad spectrum of social-ecological studies. Team members were drawn from the Nordic countries, Russia, China, the United States, and Canada. The project was transdisciplinary as well as interdisciplinary as it included collaboration with local knowledge holders. ARCPATH made significant contributions to Arctic research through an improved understanding of the mechanisms that drive climate variability in the Arctic. In tandem with this research, a combination of historical investigations and social, economic, and marine biological fieldwork was carried out for the project study areas of Iceland, Greenland, Norway, and the surrounding seas, with a focus on the joint use of ocean and sea-ice data as well as social-ecological drivers. ARCPATH was able to provide an improved framework for predicting the near-term variation of Arctic climate on spatial scales relevant to society, as well as evaluating possible related changes in socioeconomic realms. In summary, through the integration of information from several different disciplines and research approaches, ARCPATH served to create new and valuable knowledge on crucial issues, thus providing new pathways to action for Arctic communities.

关键词： Recent Ventures in Interdisciplinary Arctic Research:The ARCPATH Project

On the Chow Groups of Certain Cubic Fourfolds

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Acta Mathematica Sinica,english Series 2017年第7期33卷 887-898页

作者： robert LATeRVeeR Institut de Recherche Mathématique Avancée CNRS-Universitd de Strasbourg7 Rue Rene Descartes67084 Strasbourg CedexFrance

This note is about the Chow groups of a certain family of smooth cubic fourfolds. This family is characterized by the property that each cubic fourfold X in the family has an involution such that the induced involution on the Fano variety F of lines in X is symplectic and has a K3 surface S in the fixed locus. The main result establishes a relation between X and S on the level of Chow motives. As a consequence, we can prove finite-dimensionality of the motive of certain members of the family. Keywords Algebraic cycles, Chow groups, motives, cubic fourfolds, hyperkiihler varieties, K3 sur- faces, finite-dimensional motive

关键词： Algebraic cycles Chow groups motives cubic fourfolds hyperk?hler varieties K3 surfaces finite-dimensional motive