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科技英语学习 2009年第1期 39-41页

作者： robert Kiyosaki 张成伟

之所以有这么多的人当不成企业家，其原因之一就在于他们害怕失败。他们害怕犯错。他们担心赔钱。然而，要是人们无法克服这些心理上的恐惧，那么看好自己的饭碗，他们的日子会过得好些。

关键词：失败企业家恐惧

Dust pollen distribution on a continental scale and its relation to present-day vegetation along north-south transects in east China

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Science China Earth Sciences 2007年第2期50卷 236-246页

作者： P. COUR D. DUZER G. robert M. CALLEJA C. BEAUDOUIN Ecole Nationale Supérieure Agronomique de Montpellier 34000 Montpellier France UMR CNRS 5554 ISEM Université Montpellier 2 34000 Montpellier France Department of Earth Sciences Sun Yat-sen University

A series of dust pollen samples was collected along N-S transects in east China (18°N to 53°N latitudes). Sample sites extend from the cold-temperate zone in the north to the tropical region in the south. Pollen taxa characterize each region and reflect the natural and devastated vegetation as well as corre- sponding climatic zones. The quantitative pollen data can be used to estimate the spatial distribution of planted and introduced species. Valuable information of human disturbance of the natural forest is evaluated by quantitative comparison between dust pollen and in-situ pollen of protected forest. In addition, percentages of grass pollen vary regularly from north to south that is consistent with spatial distribution of net primary productivity in east China. Among all grasses, Artemisia and the Gramineae carry the clearest signal: their ratio increases northwards and therefore represent a suitable and con- venient tool for palaeoclimate reconstructions.

关键词： dust pollen vegetation east China human impact climate zones

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慢性多支冠状动脉狭窄犬模型的建立

第一军医大学学报 2001年第1期21卷 47-50页

作者：宾建平 robert A.Pelberg 刘伊丽查道刚 Soroosh Firoozan Sanjiv Kaul 第一军医大学南方医院心内科广东广州510515 美国弗吉尼亚大学医学中心心内科

目的建立与临床冠心病极为相似的慢性多支冠状动脉狭窄犬动物模型。方法成年犬１９只，在左前降支（ＬＡＤ）和左回旋支（ＬＣＸ）近端安放缩窄器，二维超声评价室壁增厚率（％ＷＴ），放射性微球定量分析心肌血流量（ＭＢＦ）。结果 ... 详细信息

目的建立与临床冠心病极为相似的慢性多支冠状动脉狭窄犬动物模型。方法成年犬１９只，在左前降支（ＬＡＤ）和左回旋支（ＬＣＸ）近端安放缩窄器，二维超声评价室壁增厚率（％ＷＴ），放射性微球定量分析心肌血流量（ＭＢＦ）。结果术后第７天２６个（５２％）心肌节段表现为局部室壁运动异常（ＲＷＭＡ），ＬＡＤ和ＬＣＸ供血区的平均％ＷＴ低于术前（Ｐ＜０．０５）；但ＬＡＤ和ＬＣＸ供血区的ＭＢＦ在术后第２１天才降低（Ｐ＜０．０５）。术后第４２天有３６个（７２％）心肌节段表现为ＲＷＭＡ，ＬＡＤ和ＬＣＸ供血区的平均％ＷＴ亦均低于术前（Ｐ＜０．０５），但仅ＬＣＸ供血区的ＭＢＦ保持低下（Ｐ＜０．０５）。结论慢性多支冠状动脉狭窄犬模型可产生明显的节段性左室收缩功能低下，适宜于慢性可逆性心肌收缩功能障碍的研究。

关键词：室壁增厚率心肌血流量慢性多支冠状动脉狭窄动物模型犬

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非住院腹腔镜手术初步研究

中华外科杂志 2003年第11期41卷 879-880页

作者：洪德飞李君达陈继达钟泰迪李强蔡秀军 robert K Finnley 浙江大学医学院附属邵逸夫医院外科杭州310016 Loma Linda University USA

由于非住院手术（day surgery）可明显减少医疗费用，缩短治疗时间，避免或减少医源性感染等优点，近几年来成为美国等西方国家的研究热点。腹腔镜技术和麻醉技术的显著进步，促进了全麻非住院手术的显著进步，促进了全麻非住院手术的... 详细信息

由于非住院手术（day surgery）可明显减少医疗费用，缩短治疗时间，避免或减少医源性感染等优点，近几年来成为美国等西方国家的研究热点。腹腔镜技术和麻醉技术的显著进步，促进了全麻非住院手术的显著进步，促进了全麻非住院手术的发展。据统计，2002年美国50%以上的腹腔镜胆囊切除为非住院手术（ambulatory laparoscopic cholecystectomy, ALC）。我院在完成3 000多例住院LC的基础上，开展了ALC的探索性研究。

关键词：腹腔镜手术非住院手术医源性感染术前诊断

Randomized, Placebo-Controlled Trial of Transdermal Rivastigmine for the Treatment of Encephalopathy in Liver Cirrhosis (TREC Trial)

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Open Journal of Gastroenterology 2014年第6期4卷 255-264页

作者： Patrick P. Basu Niraj James Shah Mark M. Aloysius robert S. Brown Columbia University College of Physicians & Surgeons New York USA James J. Peters VA Medical Center New York USA King’s County Hospital New York USA

Objectives: Cognitive dysfunction in patients with hepatic encephalopathy (HE) may be caused by alterations in cholinergic neurotransmission. The objective of the study was to evaluate the efficacy and safety of transdermal rivastigmine in improving cognitive function in patients with overt HE. Design: Randomized, controlled pilot study in which patients with grade 2 or 3 HE were treated with lactulose and randomized to receive either transdermal rivastigmine or placebo for 21 days. The modified encephalopathy scale (MES), object recognition test (ORT), trail test (TT), and serum ammonia were assessed at baseline weekly. Electroencephalography was performed at baseline and the final week of the study. Results: Patients were treated with lactulose (20 g/30 mL three times per day) and either transdermal rivastigmine (4.6 mg/d;n = 15) or placebo (n = 15). Transdermal rivastigmine significantly improved MES, ORT, and TT results compared with placebo (P ≤ 0.0001 at all 3 weeks for all 3 assessments). Serum ammonia improved in both treatment groups, although there was significantly greater improvement with placebo than rivastigmine after 2 weeks of treatment (P What is already known about this subject? ? Current approaches to the management of HE are primarily designed to reduce the levels of ammonia and other gut-derived toxins. ? Traditional strategies for HE treatment have included non-absorbable disaccharides (to decrease bowel transit time) or rifamixin (non-absorbable antibiotics to reduce ammoniogenic flora). ? No transdermal cholinomimetic agents have been used with oral lactulose to date, in HE. What are the new findings? ? Transdermal rivastigmine is safe for use in patients with grade 2 & 3 HE. ? Transdermal rivastigmine in combination with oral lactulose in this study is far superior to lactulose alone in improving cognitive function. How might it impact on clinical practice in the foreseeable future? ? Transdermal rivastigmine in combination with oral lactulo

关键词： Acetylcholinesterase Cholinergic Function Hepatic Encephalopathy Rivastigmine

Effects of <i>Myrothecium verrucaria</i>on Two Glyphosate-Resistant <i>Amaranthus palmeri</i>Biotypes Differing in Betacyanin Content

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American Journal of Plant Sciences 2020年第2期11卷 214-225页

作者： robert E. Hoagland Clyde Douglas Boyette Robin H. Jordan Kenneth C. Stetina Crop Production Systems Research Unit USDA-ARS Stoneville MS USA Biological Control of Pests Research Unit USDA-ARS Stoneville MS USA

Previously we found two biotypes of Amaranthus palmeri (Palmer amaranth) in a population of this economically important weed that were resistant to glyphosate but differed with respect to pigmentation. One biotype was typically red-pigmented (betacyanin) while the other was green, with no visual appearance of red hue on any plant part at any growth stage. We have also reported that a strain of Myrothecium verrucaria (MV) exhibited bioherbicidal activity against several important weeds including glyphosate-resistant Palmer amaranth. In greenhouse tests, MV was applied to these two biotypes (red and green) at two ages (3-week- and 6-week-old) and effects of this fungus monitored over a 5-day time course. Initial symptoms of MV (16 to 24 h after inoculation) were: epinastic curvature, wilting and development of lesions on leaves and stems. Generally, the younger plants tended to be more sensitive to MV than older plants. Bioherbicidal damage increased with time leading to necrosis and plant mortality and increasing disease progress. Severe loss of fresh weight occurred in both biotypes as compared to untreated plants. Results indicated that MV was effective on both biotypes, but effects on growth reduction and disease progression were more rapid and generally greater in the green biotype, suggesting that compounds responsible for red pigmentation may be more potent as defense against pathogen attack.

关键词： Betalain Bioherbicide Biological Weed Control Palmer Amaranth Pigweed

A Polymer Coated Cicaprost-Eluting Stent Increases Neointima Formation and Impairs Vessel Function in the Rabbit Iliac Artery

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Pharmacology & Pharmacy 2016年第6期7卷 226-235页

作者： Christopher McCormick robert L. Jones Roger M. Wadsworth Alexander B. Mullen Simon Kennedy Biomedical Engineering Department University of Strathclyde Glasgow UK Strathclyde Institute of Pharmacy and Biomedical Sciences University of Strathclyde Glasgow UK Institute of Cardiovascular and Medical Sciences University of Glasgow Glasgow UK

Drug-eluting stents have been successful in reducing in-stent restenosis but are not suitable for all lesion types and have been implicated in causing late stent thrombosis due to incomplete regeneration of the endothelial cell layer. In this study we implanted stents coated with cicaprost, a prostacyclin analogue with a long plasma half-life and antiproliferative effects on vascular smooth muscle cells, into the iliac arteries of rabbits. At 28-day follow-up we compared neointima formation within the stented vessels and vascular function in adjacent vessels, to assess if cicaprost could reduce restenosis without impairing vessel function. Arteries implanted with cicaprost eluting stents had significantly more neointima compared to bare metal stents. In adjacent segments of artery, endothelium-dependent relaxation was impaired by the cicaprost-eluting stent but vasodilation to an endothelium-independent vasodilator was maintained. We conclude that the presence of the polymer and sub-optimal release of cicaprost from the stent may be responsible for the increased neointma and impaired functional recovery of the endothelium observed. Further experiments should be aimed at optimising release of cicaprost and exploring different stent polymer coatings.

关键词： Cicaprost Neointima Iliac Artery Endothelium Drug-Eluting Stent

猪真皮胶原膜早期覆盖深Ⅱ度烧伤创面的实验研究

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中华烧伤杂志 1993年第4期 284-285+319+324页

作者：高智仁 Michael J.Im robert J.Spence 青海医学院附属医院烧伤科 Division of Plastic Surgery The Johns Hopkins University School of Medicine Division of Plastic Surgery The Johns Hopkins University School of Medicine 810001 Baltimore Maryland 21205U. S. A. Baltimore Maryland 21205U. S. A.

采用我们先前报道的猪皮胶原提取方法和成膜技术,制成猪真皮胶原膜。在大鼠背部以75℃、15秒,造成4cm×4cm的深Ⅱ度烧伤创面,清除坏死表皮后,治疗组早期覆盖猪真皮胶原膜,对照组创面暴露。伤后10天评定创面愈合情况。结果治疗组明显优... 详细信息

采用我们先前报道的猪皮胶原提取方法和成膜技术,制成猪真皮胶原膜。在大鼠背部以75℃、15秒,造成4cm×4cm的深Ⅱ度烧伤创面,清除坏死表皮后,治疗组早期覆盖猪真皮胶原膜,对照组创面暴露。伤后10天评定创面愈合情况。结果治疗组明显优于对照组(P<0.0001)。显示猪真皮胶原膜对深Ⅱ度烧伤创面有良好的保护作用和促进愈合的作用。

关键词：胶原真皮胶原猪真皮胶原烧伤创面愈合

Very-high-dose olanzapine for treatment-resistant schizophrenia

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Open Journal of Psychiatry 2012年第4期2卷 269-271页

作者： Jean-Marie Batail Sophie Bleher Clément Lozachmeur Gabriel robert Bruno Millet Dominique Drapier Adult Psychiatry Department Guillaume Régnier Hospital Rennes France

Treatment-resistant schizophrenia has an extremely negative impact on mental health and social life. If clozapine, the gold standard treatment, fails, there are very few options left. The literature suggests that high-dose olanzapine (20 - 60 mg/day) is a possible alternative. We report two cases in which very high doses of olanzapine were administered, with significant clinical improvements above 60 mg/day. Clinical, metabolic and cardiac tolerance was good. This report highlights the usefulness of very-high-dose olanzapine in treatment-resistant schizophrenia. The main hypotheses concerning the psychopharmacological mechanisms of very-high-dose olanzapine are discussed.

关键词： Schizophrenia Treatment Resistance High-Dose Olanzapine Treatment Tolerance