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Learning from Each Other’s Culture

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China Today 2024年第10期73卷 54-56页

作者： robert WALKER Green Templeton College University of Oxford

Successful collaboration across cultures requires understanding,acceptance and *** is as true for governments as it is for *** our world almost broken apart by the forces of geopolitical self-interest,cross-cultural understanding is the glue needed to hold it *** means recognizing the fact that as people and nations,we are all the same but different.

关键词： Other get acceptance

Resisting Economic Coercion

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China Today 2024年第6期73卷 20-23页

作者： robert WALKER Green Templeton College University of Oxford The Jingshi Academy at Beijing Normal University The Royal Society of Arts The Academy of Social Sciences

PROFESSOR Alena Douhan is a Special Rapporteur for the United Nations and a human rights *** visited China in May as part of her mandate to investigate the humanitarian consequences of the unilateral coercive measures imposed on China.“Unilateral coercive measures”are what other people tend to call sanctions-or trade embargoes or punitive *** her visit,Professor Douhan met government officials,representatives of the legislative and judicial branches,members of the diplomatic community and academia,and stakeholders from business and non-governmental organisations.

关键词： consequences imposed measures

Talking Justice,the Chinese Way

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China Today 2024年第5期73卷 50-52页

作者： robert WALKER Beijing Normal University Green Templeton College University of Oxford Royal Society of Arts and the Academy of Social Sciences in the U.K.

Western legal scholars learn from China’s approach to justice at a seminar held at Oxford *** can work better than prosecution and prison.

关键词： Way legal scholars

Nucleotide Contribution to the Functioning of SERT, Na/K ATPase and GPCR Proteins

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Journal of Biosciences and Medicines 2024年第5期12卷 61-76页

作者： Wynford robert Williams Faculty of Life Sciences & Education University of South Wales Cardiff UK

Purine nucleotides are crucial for the effective operation of cell membrane proteins maintaining the neurotransmitter responses of 5-HT. Major protein targets in the treatment of depression include SERT, N/K ATPase and GPCR. Each protein target is responsive to a specific complement of drugs: antidepressants (SERT), lithium and cardiogenic steroids (N/K ATPase), 5-HT receptor ligands (GPCR). Computational software is useful for comparing molecular similarity within ligand-ligand and ligand-nucleotide structures. Previous studies demonstrate that GPCR ligands of different pharmacologic classes display relative molecular similarity to nucleotide structures. The current study applies this methodology to compound structures modulating SERT and N/K ATPase receptors. Minimum energy conformers of SERT antagonists demonstrate relative molecular similarity to the structural template of GTP nucleotide. GTP template fits of 5-HT and psilocin are similar, whereas a SERT-like fit is one of several for the ketamine structure. Endogenous and pharmaceutical modulators of Na/K ATPase relate to adenine nucleotide. The fits of cardiogenic steroids to a cGMP template demonstrate similarities and differences between compounds. Relative molecular similarity within the structures of hormones, drugs and nucleotides has implications for neurotransmitter transport and cell signal transduction processes.

关键词： SERT SSRI GPCR Sodium/Potassium ATPase Nucleotides Depression

DeepRice: A deep learning and deep feature based classification of Rice leaf disease subtypes

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Artificial Intelligence in Agriculture 2024年第1期11卷 34-49页

作者： P.Isaac Ritharson Kumudha Raimond X.Anitha Mary Jennifer Eunice robert Andrew J Department of CSE Karunya Institute of Technology and Sciences CoimbatoreTamilnaduIndia Department of Robotics Engineering Karunya Institute of Technology and SciencesCoimbatoreIndia Department of Mechatronics Engineering Manipal Institute of TechnologyManipal Academy of Higher EducationManipalKarnataka 576104India Department of Computer Science and Engineering Manipal Institute of TechnologyManipal Academy of Higher EducationManipalKarnataka 576104India

Rice stands as a crucial staple food globally,with its enduring sustainability hinging on the prompt detection of rice leaf ***,efficiently detecting diseases when they have already occurred holds paramount importance for solving the cost of manual visual identification and chemical *** the recent past,the identification of leaf pathologies in crops predominantly relies on manual methods using specialized equipment,which proves to be time-consuming and *** study offers a remedy by harnessing Deep Learning(DL)and transfer learning techniques to accurately identify and classify rice leaf diseases.A comprehensive dataset comprising 5932 self-generated images of rice leaves was assembled along with the benchmark datasets,categorized into 9 classes irrespective of the extent of disease spread across the *** classes encompass diverse states including healthy leaves,mild and severe blight,mild and severe tungro,mild and severe blast,as well as mild and severe brown *** meticulous manual labelling and dataset segmentation,which was validated by horticulture experts,data augmentation strategies were implemented to amplify the number of *** datasets were subjected to evaluation using the proposed tailored Convolutional Neural Networks *** performance are scrutinized in conjunction with alternative transfer learning approaches like VGG16,Xception,ResNet50,DenseNet121,Inception ResnetV2,and Inception *** effectiveness of the proposed custom VGG16 model was gauged by its capacity to generalize to unseen images,yielding an exceptional accuracy of 99.94%,surpassing the benchmarks set by existing state-of-the-art ***,the layer wise feature extraction is also visualized as the interpretable AI.

关键词： Rice leaf disease Deep learning CNN Crop yield Agriculture Food security

Deciding on life-saving treatment after a violent suicide attempt:an ethical case report

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General Psychiatry 2024年第2期37卷 289-291页

作者： robert Wichers Hanna M Heller Sisco van Veen Department of Child and Adolescent Psychiatry&Psychosocial Care Amsterdam University Medical CenterLocation AMCAmsterdamThe Netherlands Amsterdam Public Health Mental Health programAmsterdamThe Netherlands Department of Hospital Psychiatry Amsterdam University Medical CenterLocation VUmcAmsterdamThe Netherlands Research Department 113 Suicide PreventionAmsterdamThe Netherlands Department of Psychiatry&Department of Ethics Law and HumanitiesAmsterdam University Medical CenterAmsterdamThe Netherlands GGZ inGeest Mental Health Care AmsterdamThe Netherlands

To the editor:In the USA alone,there were 1.7 million suicide attempts in 2021.1 Although the majority of suicide attempts are not fatal,immediate medical attention is often necessary,especially when violent methods are used.2 These methods include jumping from heights,using a firearm,crashing a motor vehicle,and lying down or jumping in front of a moving object.

关键词： treatment editor alone

Data-driven analysis of chemicals,proteins and pathways associated with peanut allergy:from molecular networking to biological interpretation

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Food Science and Human Wellness 2024年第3期13卷 1322-1335页

作者： Emmanuel Kemmler Julian Braun Florent Fauchère Sabine Dölle-Bierke Kirsten Beyer robert Preissner Margitta Worm Priyanka Banerjee Institute for Physiology Charité-University Medicine BerlinBerlin 10115Germany Member of the KFO339 FOOD@Berlin 10115Germany Si-M/“Der Simulierte Mensch”a science framework of Technische Universität Berlin and Charité-Universitätsmedizin Berlin Berlin 10115Germany Charité-Universitätsmedizin Berlin corporate member of Freie Universität BerlinHumboldt-Universität zu Berlinand Berlin Institute of HealthBerlin 10115Germany Division of Allergy and Immunology Department of DermatologyVenerology and AllergyCharité-Universitätsmedizin Berlincorporate member of Freie Universität Berlin and Humboldt-Universität zu BerlinBerlin 10115Germany Pediatrics Campus VirchowCharité-University Medicine BerlinBerlin 10115Germany

Peanut allergy is majorly related to severe food induced allergic *** food including cow's milk,hen's eggs,soy,wheat,peanuts,tree nuts(walnuts,hazelnuts,almonds,cashews,pecans and pistachios),fish and shellfish are responsible for more than 90%of food ***,we provide promising insights using a large-scale data-driven analysis,comparing the mechanistic feature and biological relevance of different ingredients presents in peanuts,tree nuts(walnuts,almonds,cashews,pecans and pistachios)and ***,we have analysed the chemical compositions of peanuts in different processed form raw,boiled and *** the data-driven approach we are able to generate new hypotheses to explain why nuclear receptors like the peroxisome proliferator-activated receptors(PPARs)and its isoform and their interaction with dietary lipids may have significant effect on allergic *** results obtained from this study will direct future experimeantal and clinical studies to understand the role of dietary lipids and PPARisoforms to exert pro-inflammatory or anti-inflammatory functions on cells of the innate immunity and influence antigen presentation to the cells of the adaptive immunity.

关键词： Allergy informatics Knowledge-graph Data analysis Food allergy Peroxisome proliferator-activated receptors Fatty acids

Angular unconformity in Pennsylvanian strata from 3-D seismic interpretation,Goldsmith Field,West Texas

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Energy Geoscience 2024年第2期5卷 298-303页

作者： Edwin I.Egbobawaye Nelly Omoruyi Abdulmutallib Aminu robert Trentham Mohamed K.Zobaa Sumit Verma Kinder Morgan MidlandTX79705USA Department of Geosciences University of Texas Permian BasinOdessaTX79762USA

The Pennsylvanian unconformity,which is a detrital surface,separates the beds of the Permian-aged strata from the Lower Paleozoic in the Central Basin *** data interpretation indicates that the unconformity is an angular unconformity,overlying multiple normal faults,and accompanied with a thrust fault which maximizes the region's structural ***,the Pennsylvanian angular unconformity creates pinch-outs between the beds above and *** computed the spectral decomposition and reflector convergence attributes and analyzed them to characterize the angular unconformity and *** spectral decomposition attribute divides the broadband seismic data into different spectral bands to resolve thin beds and show thickness *** contrast,the reflector convergence attribute highlights the location and direction of the pinch-outs as they dip south at angles between 2° and 6°.After reviewing findings from RGB blending of the spectrally decomposed frequencies along the Pennsylvanian unconformity,we observed channel-like features and multiple linear bands in addition to the faults and *** can be inferred that the identified linear bands could be the result of different lithologies associated with the tilting of the beds,and the faults may possibly influence hydrocarbon migration or act as a flow barrier to entrap hydrocarbon *** identification of this angular unconformity and the associated features in the study area are vital for the following reasons:1)the unconformity surface represents a natural stratigraphic boundary;2)the stratigraphic pinch-outs act as fluid flow connectivity boundaries;3)the areal extent of compartmentalized reservoirs'boundaries created by the angular unconformity are better defined;and 4)fault displacements are better understood when planning well locations as faults can be flow barriers,or permeability conduits,depending on facies heterogeneity and/or seal effectiveness of a fault,which

关键词： Pennsylvanian unconformity Seismic data interpretation Spectral decomposition Reflector convergence Reservoir characterization

Deterministic epidemic models overestimate the basic reproduction number of observed outbreaks

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Infectious Disease Modelling 2024年第3期9卷 680-688页

作者： Wajid Ali Christopher E.Overton robert R.Wilkinson Kieran J.Sharkey Department of Mathematical Sciences University of LiverpoolPeach StreetLiverpoolL697ZXEnglandUnited Kingdom Department of Applied Mathematics Liverpool John Moores UniversityByrom StreetLiverpoolL35UXEnglandUnited Kingdom

The basic reproduction number,R_(0),is a well-known quantifier of epidemic ***,a class of existing methods for estimating R_(0)from incidence data early in the epidemic can lead to an over-estimation of this *** particular,when fitting deterministic models to estimate the rate of spread,we do not account for the stochastic nature of epidemics and that,given the same system,some outbreaks may lead to epidemics and some may ***,an observed epidemic that we wish to control is a major *** amounts to implicit selection for major outbreaks which leads to the over-estimation *** formally characterised the split between major and minor outbreaks by using Otsu's method which provides us with a working *** show that by conditioning a‘deterministic’model on major outbreaks,we can more reliably estimate the basic reproduction number from an observed epidemic trajectory.

关键词： Estimating R_(0) Simple birth-death process Major outbreak Conditioned epidemic Stochastic fade-out