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应用高压液相层析法测定血清吡喹酮

中国寄生虫学与寄生虫病杂志 1983年第4期 35-35页

作者：肖树华,B.A.Catto,l.t.Webster,jr 中国预防医学中心寄生虫病研究所美国凯司西储大学医学院药理系美国凯司西储大学医学院药理系

本文介绍一种测定吡喹酮的高压液相层析法。此法的样品制备只需用乙酸乙酯一步提取,操作简便,并以吡喹酮的七环衍生物作内标准。本法测定吡喹酮的最低浓度为2.5ng/ml人或小鼠血清,测定吡喹酮

关键词：液相层析法人血清

接受抗逆转录病毒治疗前后有关嗜酸性毛囊炎的研究

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世界核心医学期刊文摘（皮肤病学分册） 2006年第1期2卷 27-27页

作者： Rajendran P.M Dolev J.C Heaphy jr. M.R Maurer t 李晓莉 Department of Dermatology University of California San Francisco Bldg. 90 1001 Potrero Ave San Francisco CA 94110 United States.Dr

Objective: to characterize the relationship of new eosinophilic folliculitis (EF) cases between June 30, 1994, and January 5, 2000, and antiretroviral therapy (ARt) status and immune reconstitution. Design: Retrospective cohort analysis. Setting: Dermatology clinics at a county hospital. Subjects: Fifty-seven consec utive subjects with biopsy-proved EF from the pathology database. Subject group s were as follows: native to ARt, receiving ARt without protease inhibitors/ non nucleoside reverse transcriptase inhibitors, and receiving ARt containing protea se inhibitors/nonnucleoside reverse transcriptase inhibitors. Main Outcome Measu res: Onset of EF, CD4 cell count and nadir at EF onset, and time of ARt initiati on. Results: Among the 3 groups previously described, mean CD4 cell counts (86.2 6/μl vs 113.82/μl vs 145.65/μl, respectively [Kruskal-Wallis rank sumtest, P=.15]) and nadir (68.43/μl vs 66.18/μl vs 64.17/μl, respectively [Kruskal-Wallis rank sum test, P=.41]) at EF diagnosis were not statistically different. Fifty-two subjects (91%), regardless of treatment group, had a nadir below 200/ μl. Of the subjects undergoing ARt, 28 (82%) developed EF within 6 months of i nitiating ARt; their average CD4 cell count increase was 108/μl. Of the 23 subj ects receiving protease inhibitor/nonnucleoside reverse transcriptase inhibitor -containing ARt regimens, 17 (74%) were diagnosed as having EF within 3 months , with 4 additional subjects diagnosed as having EF within 6 months (a total of 21 [91%] of the 23 subjects). this is not significantly different from the 7 (64%) of 11 subjects diagnosed as having EF at 3 and 6 months of starting ARt wit hout protease inhibitors/nonnucleoside reverse transcriptase inhibitors (P=.07) (odds ratio, 0.18; 95%confidence interval, 0.01-1.54). Conclusions: Our study shows an association between low nadir (66.28/μl) and low CD4 cell count (115.5 4/μl) and the development of EF, regardless of subjects’ARt status. However, m ost subjects

关键词：嗜酸性细胞计数免疫重建逆转录酶抑制剂蛋白酶抑制剂 allis 皮肤活检秩和检验 Krusk

EFFECtS OF CERUlOPlASMIN ON IRON tRANSPORt IN MIDBRAIN AND HIPPOCAMPUS NEURONS

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EFFECTS OF CERULOPLASMIN ON IRON TRANSPORT IN MIDBRAIN AND H...

Improving the hard magnetic properties by intragrain pinning for ta doped nanocrystalline Ce-Fe-B alloys

中国生理学会、中国神经科学会2005年神经内分泌免疫学术研讨会

作者： YKE, jr.DU, Xl DUAN, QWANG, YJ XUE, lZ lI, l ZHU, CY WANG, KP HO, l JIANG, YM MA, JQ ZHANG, lJ NIU, l WANG, ZM QIAN laboratory of Brain Iron Metabolism, Department of Applied Biology & Chemical technology, and National Key laboratory of Chinese Medicine and Molecular Pharmacology (Shenzhen), Hong Kong Polytechnic University, Hong Kong, the Biotechnology laboratory, Biomedical Research Centre, University of British Columbia, Vancouver, BC, Canada V6t 1Z3, Institute of Neurobiology and Neuropharmacology, Hebei Normal University, Shijiazhuang, Hebei, PRC 050016, Institute of Chemical biology and Pharmaceutical Sciences, Capital University of Medical Sciences, Beijing, PRC 100054

Ceruloplasmin (CP) is an abundant serum alpha-2 glycoprotein. In the brain, the greatest expression of CP is found in astrocytes surrounding the brain microvasculature. the glycosylphosphatidylinositol-anchored CP (GPI-CP) is the predominant form of this protein in the brain. Humans with mutations of the CP gene (aceruloplasminemia) can lead to brain iron accumulation and neurodegeneration. It implies that CP is essential for brain iron homeostasis. However, its precise function in brain iron transport has not been well determined. In this study, we investigated the effects of soluble CP on iron influx and efflux in primary neuronal culture

关键词： EFFECtS OF CERUlOPlASMIN ON IRON tRANSPORt IN MIDBRAIN AND HIPPOCAMPUS NEURONS

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Journal of Materials Science & technology 2019年第9期35卷 1877-1885页

作者： J.S.Zhang W. li X.F. liao H.Y. Yu l.Z. Zhao H.X. Zeng D.R. Peng Z.W. liu School of Materials Science and Engineering South China University of TechnologyGuangzhou510640China Innovative Center for Advanced Materials (ICAM) Hangzhou Dianzi UniversityHangzhou310012China

to develop Ce based permanent magnets with high performance/cost ratio, ta doping is was employed to enhance the magnetic performance of Ce-Fe-B alloys. For melt spun Cei7Fe78-xtaxB6 (x = 0-1) alloys, the coercivity Hc increases from 439 to 553 kA/m with increasing x value from 0 to 0.75. Microstructure characterizations indicate that ta doping is helpful for grain refinement. A second phase of taB2 is observed in Ce17Fe77.25tao.75B6 alloy, which acts as the pinning center of the magnetic domains, resulting in the change of coercivity mechanism from nucleation type to nucleation +pinning type. the micromagnetic simulation confirms that non-magnetic particles within hard magnetic phase can increase the demagnetization field around them and it is crucial for preventing the further magnetization reverse by pinning effect. take the advantage of ta doping for enhancing the coercivity, Ce content of Ce-Fe-B alloy can be further cut down to increase the remanence jr.due to the reduced volume fraction of CeFe2 phase and increased Fe/Ce ratio. As a result, a good combination of magnetic properties with Hc = 514 kA/m, jr.= 0.49 t, and the maximum energy product (BH)max = 36 kJ/m^3 have been obtained in Ce15Fe79.25tao.75B6 alloy. It is expected that the present work can serve as a useful reference for designing new permanent magnetic materials with low-cost.

关键词： Melt-spinning Permanent magnets Second phase Coercivity mechanism thermal stability

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管理学能力培养取向

COARSE-PARtIClE tRANSPORt IN A GRAVEl-BED RIVER

丛书名：管理学系列

2005年

作者：（美）唐·黑尔里格尔（Don Hellriegel）（美）苏珊·E.杰克逊（Susan E. Jackson）（美）小约翰·W.斯洛克姆（John W. Slocum jr.）张燕刘小涛栗晓虹译

本书重点在于对管理能力的培养方面，针对进行管理所必须具备的六种管理能力——沟通、协作、计划和执行、战略行动、全球意识以及自我管理展开了论述。

ISBN: (数字)7508603664

ISBN: (纸本)7508603664

关键词：管理学

来源：畅想之星图书光盘版（南... 评论

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International Journal of Sediment Research 1996年第2期 8-21页

作者： William W.EMMEtt1,robe.t l.BURROWS2,and Edward F.CHACHO,jr..(1 U.S.Geological Resources Division,lakewood,Colorado,USA 80225-0046)(2 U.S ,Water Resources Division,Fairbanks,Alaska,USA 99775-5170)(3 Cold Regions Research and Engineering laboratory,Fairba

ＣＯＡＲＳＥ－ＰＡＲＴＩＣＬＥＴＲＡＮＳＰＯＲＴＩＮＡＧＲＡＶＥＬ－ＢＥＤＲＩＶＥＲＷｉｌｌｉａｍＷ．ＥＭＭＥＴＴ１，ＲｏｂｅｒｔＬ．ＢＵＲＲＯＷＳ２，ａｎｄＥｄｗａｒｄＦ．ＣＨＡＣＨＯ，Ｊｒ３．（１Ｕ．Ｓ．Ｇｅｏｌ... 详细信息

ＣＯＡＲＳＥ－ＰＡＲＴＩＣＬＥＴＲＡＮＳＰＯＲＴＩＮＡＧＲＡＶＥＬ－ＢＥＤＲＩＶＥＲＷｉｌｌｉａｍＷ．ＥＭＭＥＴＴ１，ＲｏｂｅｒｔＬ．ＢＵＲＲＯＷＳ２，ａｎｄＥｄｗａｒｄＦ．ＣＨＡＣＨＯ，Ｊｒ３．（１Ｕ．Ｓ．ＧｅｏｌｏｇｉｃａｌＳｕｒｖｅｙ，Ｗａｔｅ...

关键词： Coarse-particle transport transport rates Mean Particle speed Bed-load sampler

Insulin is necessary for the hypertrophic effect of cholecystokinin-octapeptide following acute necrotizing experimental pancreatitis

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World Journal of Gastroenterology 2004年第15期10卷 2275-2277页

作者： Péter Hegyi Zoltán Rakonczayjr.Réka Sári lászló Czakó Norbert Farkas Csaba Góg József Németh János lonovics tamás takács First Department of Medicine Faculty of MedicineUniversity of Szeged Szeged H6722Hungary School of Cell and Molecular BiosciencesMedical SchoolUniversity of NewcastleNewcastle upon TyneNE2 4HHUnited Kingdom First Department of Medicine Faculty of MedicineUniversity of Szeged Szeged H6722Hungary Jr.School of Cell and Molecular BiosciencesMedical SchoolUniversity of NewcastleNewcastle upon TyneNE2 4HHUnited Kingdom First Department of Medicine Faculty of MedicineUniversity of Szeged Szeged H6722Hungary

AIM:In previous experiments we have demonstrated that by administering low doses of cholecystokinin-octapeptide (CCK-8),the process of regeneration following l-arginine (Arg)-induced pancreatitis is *** rats that were also diabetic(induced by streptozotocin,StZ),pancreatic regeneration was not *** aim of this study was to deduce whether the administration of exogenous insulin could in fact restore the hypertrophic effect of CCK-8 in diabetic-pancreatitic rats. MEtHODS:Male Wistar rats were used for the experiments. Diabetes mellitus was induced by administering 60mg/kg body mass of StZ intraperitoneally(i.p.),then,on d 8, pancreatitis was induced by 200mg/100 g body mass Arg *** at an interval of 1 *** animals were injected subcutaneously twice daily(at 7 *** 7 p.m.)with 1 μg/kg of CCK-8 and/or 2 IU mixed insulin(300g/l short- action and 700g/l intermediate-action insulin) for 14 d after pancreatitis *** this the animals were killed and the serum amylase,glucose and insulin levels as well as the plasma glucagon levels,the pancreatic mass/body mass ratio(pm/bm),the pancreatic contents of DNA,protein,amylase,lipase and trypsinogen were *** tissue samples were examined by light microscopy on paraffin-embedded sections. RESUltS:In the diabetic-pancreatitic rats treatment with insulin and CCK-8 significantly elevated pw/bm and the pancreatic contents of protein,amylase and lipase vs the rats receiving only CCK-8 ***-8 administered in combination with insulin also elevated the number of acinar cells with mitotic activities,whereas CCK-8 alone had no effect on laboratory parameters or the mitotic activities in diabetic-pancreatitic rats. CONClUSION:Despite the hypertrophic effect of CCK-8 being absent following acute pancreatitis in diabetic-rats, the simultaneous administration of exogenous insulin restored this *** results clearly demonstrate that insulin is necessary for the hypertrophic ef

关键词： Animals Diabetes Mellitus, Experimental Hypoglycemic Agents Insulin Male Pancreatitis, Acute Necrotizing Rats Rats, Wistar Regeneration Research Support, Non-U.S. Gov't Sincalide

半干旱雨养区不同覆盖方式对马铃薯土壤氮含量及分布的影响

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甘肃农业大学学报 2023年第1期58卷 55-62页

作者：夏博文逄蕾常磊吴海梅 Galimah Girmanee taylor 尚旭民周彦莉王凤仁路建龙甘肃省干旱生境作物学重点实验室甘肃兰州730070 甘肃农业大学农学院甘肃兰州730070 甘肃农业大学植物生产类实验教学中心甘肃兰州730070

【目的】探讨西北半干旱雨养区不同覆盖方式对马铃薯地土壤氮素含量及分布的影响。【方法】设玉米整秸秆带状覆盖(t_(秸秆))、黑色地膜覆盖(t_(地膜))和露地平作(t_(露地))3个处理。测定分析了2019年和2020年马铃薯开花期和成熟期的秸... 详细信息

【目的】探讨西北半干旱雨养区不同覆盖方式对马铃薯地土壤氮素含量及分布的影响。【方法】设玉米整秸秆带状覆盖(t_(秸秆))、黑色地膜覆盖(t_(地膜))和露地平作(t_(露地))3个处理。测定分析了2019年和2020年马铃薯开花期和成熟期的秸秆种植带株行间(t_(秸秆-带上))、秸秆覆盖带下(t_(秸秆-带下))、地膜下(t_(地膜))和露地对照(t_(露地))在0~120 cm土层的土壤全氮、铵态氮、硝态氮、微生物量氮和碳氮比的变化。【结果】地膜覆盖较对照显著提高了0~20cm土层的土壤速效氮含量,2 a平均提高了22.73%,降低了0~40 cm土层土壤微生物量氮含量,降低了10.01%。秸秆带状覆盖较露地能够显著提高土壤0~20 cm土层土壤全氮和速效氮含量,全氮两年平均提高了17.32%,速效氮提高了9.41%;能够显著提高0~90 cm土层土壤微生物量氮含量,平均提高了45.01%;较地膜覆盖处理显著提高了0~20 cm土层的全氮含量和0~40 cm土层微生物量氮含量,分别提高了20.98%和83.83%。【结论】秸秆带状覆盖能够有效提高土壤氮素含量,是促进农业农田可持续利用与发展,提高土壤生产潜力的有效方法。

关键词：马铃薯秸秆带状覆盖地膜覆盖全氮速效氮微生物量氮

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终止复苏:院前临终决策的新方法

世界核心医学期刊文摘（心脏病学分册） 2007年第10期3卷 4-页

作者： Feder S. Matheny R.l. loveless jr.R.S. Rea t.D. 罗亮 King County Medic One 7064 South 220th StreetKentWA 98032United States

背景:急诊医疗(EMS)工作人员常常不被允许按照家属意愿终止临终时刻复苏,尤其是在缺少书面不予复苏(DNR)志愿书的时候。目的:观察实施新指南医疗机构的EMS人员是否比未实施新指南医疗机构的EMS人员更可能终止院外心脏停搏患者的复苏抢... 详细信息

背景:急诊医疗(EMS)工作人员常常不被允许按照家属意愿终止临终时刻复苏,尤其是在缺少书面不予复苏(DNR)志愿书的时候。目的:观察实施新指南医疗机构的EMS人员是否比未实施新指南医疗机构的EMS人员更可能终止院外心脏停搏患者的复苏抢救。设计:

关键词：复苏抢救患者 EM 心脏停搏