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Study of a.giotensin Converting Enzyme Gene Polymorphism in Egyptia. Type 2 Dia.etes Mellitus with Dia.etic Kidney Disea.e

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Interna.iona. Journa. of Clinica. Medicine 2018年第8期9卷 629-643页

作者： rizk a. el-baz a.a. M. Wa.a.el-Sha.ma. Ma.ra.a. a.med Ra.a. a. el-Ta.a. Zeina. Ibra.ea. a.y Genetics Unit Children Hospital Mansoura University Mansoura Egypt Dia.etes & Endocrine Unit Internal Medicine Hospital Faculty of Medicine Mansoura University Mansoura Egypt Fa.ulty of Science Tanta University Tanta Egypt

Objective: Dia.etic kidney disea.e DKD (Dia.etic nephropa.hy DN) is considered one of the chronic micro va.cula. complica.ions of dia.etes mellitus a.d considered the commonest ca.se lea.ing to chronic rena. fa.lure a.d chronic rena. dia.ysis. Genetic susceptibility ha. been implica.ed in DKD. The a.giotensin converting enzyme (a.E) is one of the key roles in the renin a.giotensin system ca.ca.e by converting a.giotensin I to a.giotensin II which pla.s a.key role in regula.ion of blood pressure a. well a. electrolytes a.d fluid ba.a.ce. This study a.dressed the a.socia.ion of (a.E) gene polymorphisms with DN in Egyptia. (T2DM) pa.ients. Methods: Our resea.ch comprised of 75 ca.es of T2DM with dia.etic kidney disea.e, 100 ca.es of T2DM without DKD a.d 94 hea.thy volunteers. Different genotypes of a.E gene were determined by SSP-PCR a.a.ysis. Results: Gene polymorphism of a.E (DD, ID, II) in dia.etic pa.ient with DKD is 44%, 52%, 4% respectively a.d for T2DM individua.s without DKD is 23%, 72%, 5% respectively. (DD) ha. significa.t higher frequencies in T2DM pa.ients with DKD compa.ed to those without DKD (p a.d (ID) ha. significa.t higher frequencies in T2DM without DKD (p a.ed tha. there is a. a.socia.ion between a.E gene polymorphisms a.d susceptibility of dia.etic pa.ients to be a.fected by dia.etic kidney disea.e. Conclusion: From our results, we ca. conclude tha. genotype of a.E in Egypt DD is the genotype of ca.es dia.etic kidney disea.e. So the presence of D a.lele ha. a.significa.t rela.ion with dia.etic kidney disea.e. Our da.a.confirm the role of a.E in its rela.ionship with dia.etic kidney disea.e in Egyptia. type 2 dia.etic pa.ients.

关键词： a.E Gene Polymorphism Insertion/Deletion Type 2 Dia.etes Mellitus T2DM Dia.etic Kidney Disea.e Dia.etic Nephropa.hy Microva.cula. Complica.ions of Dia.etes Mellitus

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Pla.ma.ignition threshold dispa.ity between silver na.opa.ticle-ba.ed ta.get a.d bulk silver ta.get a. different la.er wa.elengths

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Pla.ma.Science a.d Technology 2019年第1期21卷 63-71页

作者： a.M el SHERBINI M M Ha.Ra.S M R M rizk E a.el-Ba.a.Y La.ora.ory of La.er a.d New Ma.eria.s Faculty of Science Cairo University Fa.ulty of Engineering Electrical Engineering Department Alexandria University

Pla.ma.ignition threshold of na.opa.ticle-ba.ed a.d bulk silver ta.gets wa. mea.ured in a.r. The pla.ma.wa. initia.ed by a.Nd:Ya. la.er a. wa.elengths of 355, 532, a.d 1064 nm. The pla.ma.ignition wa. monitored utilizing the prominent a. I line a. 546.5 nm. Lower ignition thresholds of the na.opa.ticle-ba.ed silver ta.get were estima.ed a. 0.4?±?0.02, 0.34?±?0.04, a.d 0.27?±?0.035 J cm^(-2) coupled with the different la.er wa.elengths, respectively. In contra.t, the bulk silver ta.get pla.ma.exhibited a. order of ma.nitude higher ignition threshold. a.three orders of ma.nitude enha.ced emission intensity from the na.o-ba.ed ta.get over the bulk ta.get wa. a.hieved a. lower levels of la.er irra.ia.ion. a.reduction of the therma. diffusion length of the na.osilver wa. a.sumed in order to theoretica.ly predict this reduction in the pla.ma.threshold. In a.dition, the effect of self-reversa. on the resona.ce lines wa. ta.en into considera.ion.

关键词： NelIBS enha.cement na.osilver la.er pla.ma threshold

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Locomotion-ba.ed Hybrid Sa.p Swa.m a.gorithm for Pa.a.eter Estima.ion of Fuzzy Representa.ion-ba.ed Photovolta.c Modules

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Journa. of Modern Power Systems a.d Clea. Energy 2021年第2期9卷 384-394页

作者： rizk M.rizk-a.la. a.oul ella.Ha.sa.ien the Fa.ulty of Engineering Menoufia UniversityShebin El-KomEgypt Scientific Resea.ch Group in Egypt CarioEgypt the Fa.ulty of Computers a.d a.tificia. Intelligence Cairo UniversityCairoEgypt

Identifying the pa.a.eters of photovolta.c(PV)modules is significa.t for their design a.d *** of the insta.ilities in the wea.her a.tion a.d la.d surfa.e of the ea.th,which ca.se errors in mea.uring,a.novel fuzzy representa.ion-ba.ed PV module is formula.ed a.d *** this pa.er,a.novel locomotion-ba.ed hybrid sa.p swa.m a.gorithm(LHSSa.is presented to identify the pa.a.eters of PV modules a.cura.ely a.d *** the LHSSa.better lea.er sa.ps ba.ed on pa.ticle swa.m optimiza.ion(PSO)a.e incorpora.ed to the tra.itiona. sa.p swa.m a.gorithm(SSa.in a.seria.ized scheme with the a.m of providing more va.ua.le informa.ion for the lea.er sa.ps of the *** this integra.ion,the proposed LHSSa.ca. esca.e the loca. optima.a. well a. guide the seeking process to a.ta.n the promising *** proposed LHSSa.is investiga.ed on different PV models,i.e.,single-diode(SD),double-diode(DD),a.d PV module in crisp a.d fuzzy *** compa.ing with different a.gorithms,the comprehensive results a.firm tha. the LHSSa.ca. a.hieve a.highly competitive performa.ce,especia.ly on qua.ity a.d relia.ility.

关键词： Sa.p swa.m a.gorithm(SSa. pa.ticle swa.m optimiza.ion(PSO) photovolta.c(PV)model hybridiza.ion

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Hea.th problems a.ong street children seeking ca.e in the Center for Socia. a.d Preventive Medicine in Egypt

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World Journa. of Pedia.rics 2017年第5期13卷 503-507页

作者： Hoda.Ibra.im rizk Niha. Moha.ed el Rifa. Ha.a.Moha.ed a.oulgha. Public Hea.th a.d Community Medicine Depa.tment Faculty of MedicineCairo UniversityCairoEgypt Pedia.rics Depa.tment Faculty of MedicineCairo UniversityCairoEgypt

Ba.kground:In Egypt,a.ound 1 million children a.e on the *** children's hea.th is a. issue tha. is not well *** objective of the current study wa. to determine the hea.th problems of a.ta.geted group of street children seeking medica. ca.e a.d to genera.e a.hypothesis a.out the positive/nega.ive role of street children ca.e ***:a.cross-sectiona. study wa. done on 2169 street children who sought medica. ca.e a. el-Ba.ma.clinic a. the Center for Socia. a.d Preventive Medicine in Ca.ro University Children Hospita. from Ja.ua.y 2011 to July ***:Respira.ory illnesses a.d skin problems were the most preva.ent conditions,a.fecting 485 (22.4%) a.d 359 (16.6%) of the pa.ients,*** issues a.d tra.ma.were significa.tly higher a.ong the a.olescent *** a.d ga.trointestina. problems were significa.tly higher a.ong children a.ed less tha. 2 *** a.d ca.dia. problems were significa.tly higher a.ong those referred from orga.iza.ions wherea. tra.ma.wa. significa.tly higher a.ong those coming directly from the streets.a.significa.t proportion of children a. the extremes of the studied a.e spectrum were coming directly from the *** tra.smitted infections were ra.e ***:Respira.ory a.d skin disea.es were the ma.or morbidity problems a.ong street children,especia.ly a.olescent *** a.forded opportunities for a.cess to different hea.th ca.e services.

关键词： Egypt hea.th problems street children

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Cha.a.teristics Study on Bi-Pb Ba.ed a.loys Quenched from Melt

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Journa. of Ma.eria.s Science & Technology 2009年第4期25卷 449-453页

作者： rizk Mosta.a.Sha.a.y Meta. Physics La.ora.ory Physics DepartmentFaculty of ScienceMansoura University

Three different bismuth-lea. systems na.ely, Wood＇s a.loy （Bi50Pb25Sn12.5Cd12.5）, Newton＇s a.loy （Bi50Pb31.2Sn18.8） a.d Rose＇s a.loy （B50Pb28Sn22）, with one used a. fusible a.loys were quenched from melt by melt spinning technique. Therma. a.a.ysis, structure a.d mecha.ica. properties of a.l a.loys ha.e been studied a.d a.a.yzed. From X-ra. diffra.tion a.a.ysis, a. intermeta.lic compound pha.e, designa.ed Pb7Bi3 is detected. The forma.ion of a. intermeta.lic compound pha.e ca.ses a.pronounced increa.e in the electrica. resistivity. The Wood＇s a.loy conta.ning-ca.mium exhibits mecha.ica. properties superior to both the Newton＇s a.d Rose＇s a.loys. The presence of ca.mium in Wood＇s a.loy decrea.es its melting point. Wood＇s a.loy ha. better properties, which ma.e it useful in va.ious a.plica.ions such a. in protection shields for ra.iothera.y, locking of mecha.ica. devices a.d welding a. low tempera.ure.

关键词： Therma. properties electrica. resistivity Mecha.ica. properties Ra.iothera.y a.d fusible a.loys

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a.sessment of lnc RNa.Ga.5, lnc RNa.HEIH, lnc RNa.BISPR a.d its m RNa.BST2 a. serum innova.ive non-inva.ive bioma.kers: Recent insights into Egyptia. pa.ients with hepa.itis C virus type 4

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World Journa. of Ga.troenterology 2020年第2期26卷 168-183页

作者： Nourha. M el Sa.a.oty Ma.wa.I Sha.a.ek Ra.y S Gha.t Shohda.a.el-Ma.a.hy Sherine M rizk Ma.a.M el-Sa.a.hi Biochemistry Section PharmacologyToxicology and Biochemistry DepartmentFaculty of Pharmaceutical Sciences and Pharmaceutical IndustriesFuture UniversityCairo 11795Egypt Interna. Medicine Gastroenterology and Hepatology DepartmentFaculty of MedicineAin Shams UniversityCairo 11566Egypt Biochemistry Depa.tment Faculty of PharmacyCairo UniversityCairo 11562Egypt

Ba.KGROUND Hepa.itis C virus(HCV)infection a.d its consequent complica.ions a.e undenia.ly a.public hea.th burden worldwide,pa.ticula.ly in *** evidence suggests tha. ma.y lncRNa. ha.e releva.t roles in vira. infections a.d a.tivira. *** To investiga.e the expression profiles of circula.ing lncRNa.a.5,lncRNa.EIH,lncRNa.ISPR a.d mRNa.ST2 in na.ve,trea.ed a.d rela.sed HCV Egyptia. pa.ients,to elucida.e rela.ion to HCV infection a.d their effica.y a. innova.ive bioma.kers for the dia.nosis a.d prognosis of HCV *** One hundred a.d thirty HCV-infected Egyptia. pa.ients a.d 20 hea.thy controls were included in this *** lncRNa. a.d mRNa.ST2 were mea.ured using qua.tita.ive rea.-time polymera.e cha.n rea.tion(qRT-PCR).RESULTS Our results indica.ed tha. serum lncRNa.a.5 a.d LncRNa.ISPR were upregula.ed,wherea. mRNa.BST2 a.d LncRNa.HEIH were downregula.ed in na.ve *** contra.t,HCV pa.ients trea.ed with sofosbuvir a.d simeprevir;with sofosbuvir a.d da.la.a.vir;or with sofosbuvir,da.la.a.vir a.d riba.irin exhibited lower levels of lncRNa.a.5 a.d lncRNa.ISPR with higher mRNa.ST2 compa.ed to na.ve ***,pa.ients rela.sed from sofosbuvir a.d simeprevir showed higher levels of these lncRNa. with lower mRNa.ST2 compa.ed to trea.ed ***5 a.d lncRNa.ISPR were positively correla.ed with vira. loa. a.d a.T a. Pa. mRNa.ST2 wa. nega.ively correla.ed with vira. loa. a. Pa.d a.T a. Pa.significa.t positive correla.ion between lncRNa.HEIH a.d a.P wa. observed a. Pa. expression of these RNa. suggests their involvement in HCV pa.hogenesis or a.tivira. response a.d highlights their promising roles in dia.nosis a.d prognosis of HCV.

关键词： lncRNa.Ga.5 lncRNa.BISPR mRNa.BST2 lncRNa.HEIH Hepa.itis C Bioma.kers

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Sma.t Prediction for Sea.less Mobility in F-HMIPv6 Ba.ed on Loca.ion Ba.ed Services

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China.Communica.ions 2018年第4期15卷 192-209页

作者： ra.ya.rizk heba.na.ha.t electrica. Engineering Depa.tment Port Said University Port Said 42523 Egyp

This pa.er proposed a.new scheme for smooth ha.doff over F-HMIPv6 networks ba.ed on Loca.ion Ba.ed Services(LBS). It uses the a.a.la.le informa.ion a.out mobile node(MN) such a. user mobility pa.terns a.d MN's velocity to reduce ha.doff la.ency. In the proposed scheme, the movement pa.tern of users pla.s a. importa.t role in the performa.ce a.a.ysis. The proposed scheme develops LBS tha. records a.number of mobility pa.terns ba.ed on user da.ly beha.ior, a.d exploits these informa.ion to reduce the ha.doff la.ency. The proposed scheme is a.a.yzed a.d compa.ed with F-HMIPv6 protocol. The results show tha. it improves the performa.ce in terms of ha.doff la.ency, pa.ket delivery cost, a.d loca.ion upda.e cost. Specifica.ly, the proposed scheme a.hieves the tra.eoff between rea.izing a.smooth ha.doff a.d minimizing the cost tha. is the dema.d for a.l customers of mobile services.

关键词： Cost functions F-HMIPv6 loca.tion ba.ed services ma.ro ha.doff mobilityma.a.ement mobility prediction.

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Impa.t of pedia.ric tra.ma.ic bra.n injury on hippoca.pa. neurogenesis

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Neura. Regenera.ion Resea.ch 2021年第5期16卷 926-933页

作者： Ma.ia. rizk Justin Vu Zhi Zha.g Depa.tment of Na.ura. Sciences University of Michigan-DearbornDearbornMIUSA

Tra.ma.ic bra.n injury(TBI)is a.ma.or ca.se of morta.ity a.d morbidity in the pedia.ric *** a.va.ces in medica. ca.e,the morta.ity ra.e of pedia.ric TBI ha. ***,more children a.d a.olescents a.e living with TBI-rela.ed cognitive a.d emotiona. impa.rments,which nega.ively a.fects the qua.ity of their *** hippoca.pa. neurogenesis pla.s a. importa.t role in cognition a.d mood *** in a.ult hippoca.pa. neurogenesis a.e a.socia.ed with a.va.iety of neurologica. a.d neurodegenera.ive disea.es,including *** endogenous hippoca.pa. neurogenesis a.ter TBI merits significa.t ***,TBI a.fects the function of neura. stem/progenitor cells in the denta.e gyrus of hippoca.pus,which results in a.erra.t migra.ion a.d impa.red dendrite development of a.ult-born ***,a.better understa.ding of a.ult hippoca.pa. neurogenesis a.ter TBI ca. fa.ilita.e a.more successful neuro-restora.ion of da.a.e in imma.ure *** injuries,such a. neuroinfla.ma.ion a.d oxida.ive stress,exert a.significa.t impa.t on hippoca.pa. ***,a.va.iety of thera.eutic a.proa.hes ha.e been proposed for a.eliora.ing seconda.y TBI *** this review,we discuss the uniqueness of pedia.ric TBI,a.ult hippoca.pa. neurogenesis a.ter pedia.ric TBI,a.d current efforts tha. promote neuroprotection to the developing bra.ns,which ca. be levera.ed to fa.ilita.e neuroregenera.ion.

关键词： a.ult hippoca.pa. neurogenesis a.trocytes development microglia neuroinfla.ma.ion neuroregenera.ion oxida.ive stress pedia.ric tra.ma.ic bra.n injury pla.ticity stem cell

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Cycliza.ion of 4,5-Dia.ino Pyra.ole Deriva.ives a.d Their a.tiba.teria. a.tivities

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Chinese Journa. of Chemistry 2011年第7期29卷 1451-1459页

作者： rizk, Ha.a.F. EI-Ba.a.i, Ma.moud a. Ibra.im, Seha. a. EI-Bora., Moha.ed a. Depa.tment of Chemistry Faculty of Science Tanta University Tanta Egypt

a.convenient synthesis of intermedia.e 4,5-dia.ino-3-a.yl-l-phenylpyra.oles 4a.-4c wa. reported. The different cycliza.ion rea.tions were ca.ried out with cha.cone, 2-merca.toa.etic a.id a.d p-a.isia.dehyde, ethyl chloroforma.e, glyoxa. a.d thiourea.to a.ford different N a.d S conta.ning heterocycles. The rea.tion conditions were compa.ed by conventiona. hea.ing a.d microwa.e irra.ia.ion. The structures of the cycliza.ion products were de- termined by a.a.ytica. a.d spectroscopic da.a. a.l the synthesized compounds were screened for a.tiba.teria. a.tivities in vitro.

关键词： 4,5-dia.inopyra.ole cycliza.ion fused heterocyclic ring systems microwa.e chemistry a.tiba.teria. a.tivities

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Utility of endoscopic ultra.ound in pa.crea.itis:a.review

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World Journa. of Ga.troenterology 2007年第47期13卷 6321-6326页

作者： Ma.ed K rizk Henning Gerke University of Iowa.Hospita.s a.d Clinics Division of Gastroenterology and Hepatology Department of Internal Medicine 200 Hawkins Drive Iowa City IA 52242 United States

The close proximity of the endoscopic ultra.ound probe to the pa.crea. results in superior spa.ia. resolution compa.ed to CT sca. a.d MRI. In a.dition, endoscopic ultra.ound (EUS) is a.minima.ly inva.ive procedure tha. does not sha.e the rela.ively high complica.ion ra.e of ERCP. Due to these a.va.ta.es, EUS ha. evolved into a. importa.t technique to a.sess pa.crea.obilia.y disea.e. This review will discuss the role of EUS in pa.ients with pa.crea.itis. The indica.ions ca. be divided into a.ute pa.crea.itis a.d chronic pa.crea.itis. In a.ute pa.crea.itis, EUS is used to determine the etiology; in suspected chronic pa.crea.itis it is helpful to esta.lish the dia.nosis. La.tly, this review will discuss bilia.y pa.crea.itis with suspicion for persistent choledocholithia.is.

关键词： Idiopa.hic pa.crea.itis a.ute pa.crea.itis Chronic pa.crea.itis Endsocopic ultra.ound Endosonogra.hy Pa.crea. divisum Cholelithia.is Microlithia.is Choledocholithia.is Bilia.y pa.crea.itis

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