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Rare Metals 2021年第5期40卷 1118-1125页

作者： Shammy Laj Dhania Archana Chauhan ritu Langyan Department of Chemistry Kurukshetra UniversityKurukshetra 136119India

In present work,five novel europium complexes[Eu(L)3·Phen(2),Eu(L)3·Bipy(3),Eu(L)3·Neo(4),Eu(L)3·Biq(5)and Eu(L)3·Batho(6)]were synthesized,derived from[Eu(L)3·2 H_(2)O](1)complex by using ligand(HL)5-hydroxy-2-(hydroxymethyl)-4 H-pyran-4-one and coligands 1,10-phenanthroline,bipyridine,neocuproine,2,2’-biquinoline and *** order to seek excellent photoluminescent properties,coligands were introduced in the complexes to form a rigid conjugated system,thus enhancing luminescence properties of *** synthesized complexes reveal four narrow characteristic emission lines of Eu(III)consistent with ^(5)D0→^(7)FJ transitions,where J=0,1,2 and 3 at about 580,595,614 and 650 nm,*** ^(5)D0→^(7)F_(2) transition is responsible for strong red *** coordinate diagram also indicates that x,y coordinates lie in deep red *** data are in favour of high thermal stability of synthesized *** to their high thermal stability and strong red luminescence,these complexes might be used in fabrication of optoelectronic devices.

关键词： Photoluminescence Europium complexes Color coordinates Optoelectronic devices Thermal stability

Potential of biocontrol agents against Ganoderma lucidum causing basal stem rot in mesquite(Prosopis cineraria)in arid regions of India

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Journal of Forestry Research 2021年第3期32卷 1269-1279页

作者： ritu Mawar Deepesh Sharma Ladhu Ram ICAR-Central Arid Zone Research Institute Jodhpur 342003India College of Horticulture and Forestry JhalarapatanJhalawar 326001India

This study investigates the potential of native biocontrol agents(BCAs)as controls against Ganoderma lucidum causing root rot mortality in Indian *** disease is prevalent in sandy soils where trees grow under rainfed *** addition,a beetle namely A canthophorus serraticornis damages the roots,resulting in increasing vulnerability of the host thereby allowing easy of the *** dual culture tests,Ganoderma infected cowpea root bit experiment and compatibility with insecticides revealed that the three BCAs(Trichoderma longibrachiatum,***,and Aspergillus nidulans)significantly inhibited *** mycelial *** highest mycelial growth inhibition(47.6%)was recorded after 96 h followed by 39.8%and 29.3%at 72 and 48 h,respectively,by *** free filtrates of ***,***,and *** were superior in inhibiting mycelium growth.A low concentration(3 ml)of *** was more effective in inhibiting mycelium growth compared to other *** P rosopis julifl ora compost and onion residue compost amendments as food substrates favored the growth of these BCAs,which ultimately reduced the viability of Ganoderma-colonized root bits of *** on compatibility between insecticides and BCAs suggests that ***,harzianum and *** can be combined with phorate or chloropyriphos(both organophosphates)at variable concentrations if amended together for partially infected trees,or as a prophylactic measure in healthy *** studies demonstrate that there is considerable opportunity for using native BCAs against *** in managing root rot disease.

关键词： Trichoderma longibrachiatum Trichoderma harzianum Aspergillus nidulans Prosopis cineraria Onion residues Prosopis juliflora compost

Sarve:synthetic data and local differential privacy for private frequency estimation

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Cybersecurity 2022年第4期5卷 97-116页

作者： Gatha Varmal ritu Chauhan Dhananjay Singh Amity Institute of Information Technology Amity UniversityNoidaIndia Center for Computational Biology and Bioinformatics Amity UniversityNoidaIndia Department of Electronics Engineering HUFSSeoulKorea

The collection of user attributes by service providers is a double-edged *** are instrumental in driving statistical analysis to train more accurate predictive models like *** analysis of the collected user data includes frequency estimation for categorical ***,the users deserve privacy guarantees against inadvertent identity *** algorithms called frequency oracles were developed to randomize or perturb user attributes and estimate the frequencies of their *** propose Sarve,a frequency oracle that used Randomized Aggregatable Privacy-Preserving Ordinal Response(RAPPOR)and Hadamard Response(HR)for randomization in combination with fake *** design of a service-oriented architecture must consider two types of complexities,namely computational and *** functions of such systems aim to minimize the two complexities and therefore,the choice of privacy-enhancing methods must be a calculated *** variant of RAPPOR we had used was realized through bloom flters.A bloom filter is a memory-efficient data structure that offers time complexity of O(1).On the other hand,HR has been proven to give the best communication costs of the order of log(b)for b-bits ***,Sarve is a step towards frequency oracles that exhibit how privacy provisions of existing methods can be combined with those of fake data to achieve statistical results comparable to the original *** also implemented an adaptive solution enhanced from the work of Arcolezi et *** use of RAPPOR was found to provide better privacy-utility tradeoffs for specific privacy budgets in both high and general privacyregimes.

关键词： Synthetic data Differential privacy Frequency estimation Frequency oracle Privacy

Acclimatization of microalgae Arthrospira platensis for treatment of heavy metals in Yamuna River

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Water Science and Engineering 2020年第3期13卷 214-222页

作者： Nilesh Kumar Shriya Hans ritu Verma Aradhana Srivastava University School of Chemical Technology Guru Gobind Singh Indraprastha UniversityNew Delhi 110078India

Bioaccumulation and biosorption in microalgae are effective approaches for the removal of heavy metals(HMs)from river *** objective of this study was to investigate the potential for use of acclimatized microalgae in the removal of HMs from the Yamuna River water as an acclimatizing *** active culture of Arthrospira platensis(***)was acclimatized to HMs up to a concentration of 100 mg/*** was gradually exposed to increasing concentrations of HMs in five subsequent batches with a step increase of 20 mg/L to acclimatize live cells in the simulated Yamuna River *** presence of high levels of HMs in the Yamuna River water caused growth *** empirical growth inhibition model was developed,and it predicted high threshold concentrations of HMs(210.7e424.5 mg/L),producing a positive specific growth rate of *** also showed high average removal efficiencies of HMs,including 74.0%for Cu,77.0%for Cd,50.5%for Ni,76.0%for Cr,76.5%for Pb,and 63.5%for Co,from HMs-enriched Yamuna River *** findings demonstrated that the maximum specific removal amounts of Cu,Cd,Ni,Cr,Pb,and Co were 54.0,58.0,39.0,62.8,58.9,and 45.3 mg/g,*** maximum yields of the value-added products chlorophyll and phycocyanin were 2.5 mg/g(in a batch of 40 mg/L for Cd)and 1054 mg/g(in a batch of 20 mg/L for Cu),***,acclimatized *** was proven to be a potential microalga not only for sequestration of HMs but also for production of valuable pigments.

关键词： Yamuna River A.platensis Heavy metals Acclimatization Biosorption Pigments

Attenuation of Collagen Induced Arthritis by Centella asiatica Methanol Fraction via Modulation of Cytokines and Oxidative Stress

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Biomedical and Environmental Sciences 2014年第12期27卷 926-938页

作者： Shikha Sharma ritu Gupta Sonu Chand Thaku Centre for Interdisciplinary Research in Basic Sciences Jamia Millia Islamia Lab Oncology All India Institute of Medical Sciences

Objective To investigate the anti-inflammatory, antioxidant and anti-arthritic effects of Centello asiatica methanolfraction （CAME） on collagen-induced arthritis （ClA）, an animal model of rheumatoid arthritis. Methods Arthritis was induced in female wistar rats by immunization with porcine type II collagen. The CIA rats were treated orally with CaME （50, 150, and 250 mg/kg/day） for 15 d （beginning on day 21 of the experimental period）. The clinical, histological, biochemical, and immunological parameters were assessed. Results CaME treatment （150 and 250 mg/kg） significantly attenuated the severity of CIA and reduced the synovial inflammation, cartilage erosion, and bone erosion as evident from both histological and radiographic data. The escalated plasma levels of pro-inflammatory cytokines TNF-α, IL-1β, IL-6, and IL-12 alongwith nitric oxide in CIA rats decreased significantly on CaME treatment. The serum levels of type-Ⅱ collagen antibody were significantly lower in rats of CaME （150 and 250 mg/kg） treated group than those in the arthritic group. Furthermore, by inhibiting the above mediators, CaME also contributed towards the reversal of the disturbed antioxidant levels and peroxidative damage. Conclusion Our results clearly indicate that oral administration of CaME suppresses joint inflammation, cytokine expression as well as antioxidant imbalance, thereby contributing to an amelioration of arthritis severity in CIA rats.

关键词： Centella asiatica Collagen-Induced arthritis Inflammation Oxidative stress Antioxidants Anti-Inflammatory

Colon cancer and their targeting approaches through nanocarriers:A review

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Asian Pacific Journal of Tropical Biomedicine 2023年第3期13卷 104-111页

作者： Richa Kumari Nitin Sharma ritu Karwasra Kushagra Khanna Department of Pharmaceutics ISF College of PharmacyFerozepur GT RoadMogaPunjab142001India Central Council for Research in Unani Medicine Ministry of AyushJanakpuriNew Delhi110058India Faculty of Pharmaceutical Science UCSI UniversityKualalumpur56000Malaysia

Colon cancer is the fifth most common type of cancer in the *** cancer develops when healthy cells in the lining of the colon or rectum alter and grow uncontrollably to form a mass known as a *** major medical improvements,colon cancer is still one of the leading causes of cancer-related mortality *** of the main issues of chemotherapy is toxicity related to conventional *** targeted delivery systems are considered the safest and most effective by increasing the concentration of a therapeutic substance at the tumor site while decreasing it at other ***,these delivery systems required lower doses for high therapeutic value with minimum side *** current review focuses on targeting therapeutic substances at the desired site using ***,the diagnostic applications of nanocarriers in colorectal cancer are also discussed.

关键词： Colon cancer Targeting approaches Chemotherapies Nanocarriers Gold nanoparticles Liposomes

Renin-angiotensin system blockers-SGLT2 inhibitorsmineralocorticoid receptor antagonists in diabetic kidney disease:A tale of the past two decades!

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World Journal of Diabetes 2022年第7期13卷 471-481页

作者： Awadhesh Kumar Singh ritu Singh Department of Diabetes&Endocrinology G.D Hospital&Diabetes InstituteKolkata 700013West BengalIndia

Several pharmacological agents to prevent the progression of diabetic kidney disease(DKD)have been tested in patients with type 2 diabetes mellitus(T2DM)in the past two *** the exception of renin-angiotensin system blockers that have shown a significant reduction in the progression of DKD in 2001,no other pharmacological agent tested in the past two decades have shown any clinically meaningful ***,the sodium-glucose cotransporter-2 inhibitor(SGLT-2i),canagliflozin,has shown a significant reduction in the composite of hard renal and cardiovascular(CV)endpoints including progression of end-stage kidney disease in patients with DKD with T2DM at the top of reninangiotensin system blocker *** SGLT-2i,dapagliflozin,has also shown a significant reduction in the composite of renal and CV endpoints including death in patients with chronic kidney disease(CKD),regardless of T2DM *** positive findings on renal outcomes were recently reported as a top-line result of the empagliflozin trial in patients with CKD regardless of ***,the full results of this trial have not yet been *** the use of older steroidal mineralocorticoid receptor antagonists(MRAs)such as spironolactone in DKD is associated with a significant reduction in albuminuria outcomes,a novel non-steroidal MRA finerenone has additionally shown a significant reduction in the composite of hard renal and CV endpoints in patients with DKD and T2DM,with reasonably acceptable side effects.

关键词： Renin-angiotensin system blockers SGLT-2 inhibitors Mineralocorticoid receptor antagonist Diabetic kidney disease Chronic kidney disease Renal outcomes Cardiovascular outcomes

A new approach for real time object detection and tracking on high resolution and multi-camera surveillance videos using GPU

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Journal of Central South University 2016年第1期23卷 130-144页

作者： Mohammad Farukh Hashmi ritu Pal Rajat Saxena Avinash G.Keskar Department of Electronics and Communication Engineering Visvesvaraya National Institute of Technology

High resolution cameras and multi camera systems are being used in areas of video surveillance like security of public places, traffic monitoring, and military and satellite imaging. This leads to a demand for computational algorithms for real time processing of high resolution videos. Motion detection and background separation play a vital role in capturing the object of interest in surveillance videos, but as we move towards high resolution cameras, the time-complexity of the algorithm increases and thus fails to be a part of real time systems. Parallel architecture provides a surpass platform to work efficiently with complex algorithmic solutions. In this work, a method was proposed for identifying the moving objects perfectly in the videos using adaptive background making, motion detection and object estimation. The pre-processing part includes an adaptive block background making model and a dynamically adaptive thresholding technique to estimate the moving objects. The post processing includes a competent parallel connected component labelling algorithm to estimate perfectly the objects of interest. New parallel processing strategies are developed on each stage of the algorithm to reduce the time-complexity of the system. This algorithm has achieved a average speedup of 12.26 times for lower resolution video frames(320×240, 720×480, 1024×768) and 7.30 times for higher resolution video frames(1360×768, 1920×1080, 2560×1440) on GPU, which is superior to CPU processing. Also, this algorithm was tested by changing the number of threads in a thread block and the minimum execution time has been achieved for 16×16 thread block. And this algorithm was tested on a night sequence where the amount of light in the scene is very less and still the algorithm has given a significant speedup and accuracy in determining the object.

关键词： central processing unit (CPU) graphics processing unit (GPU) morphology connected component labelling (CCL)

Relook at DPP-4 inhibitors in the era of SGLT-2 inhibitors

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World Journal of Diabetes 2022年第6期13卷 466-470页

作者： Awadhesh Kumar Singh ritu Singh Department of Diabetes&Endocrinology G.D Hospital&Diabetes InstituteKolkata 700013West BengalIndia

SGLT-2 inhibitors(SGLT-2Is)have significantly improved cardio-renal outcomes and are preferred agents in people with cardiovascular diseases,heart failure,and diabetic kidney ***,GLP-1 receptor agonists(GLP-1RAs)have significantly improved atherosclerotic cardiovascular *** this end,DPP-4 inhibitors(DPP-4Is)are cardiac-neutral *** long-acting GLP-1RAs have shown a favorable HbA1c lowering compared to DPP-4Is,there is no clinically meaningful HbA1c lowering difference between SGLT-2Is vs ***,the glucose-lowering potential of SGLT-2Is gets compromised with a progressive decline in renal functions,unlike ***,the HbA1c lowering potential of DPP-4Is is favorable in people with T2DM having a modest baseline HbA1c(8.0%-8.5%)compared with SGLT-2Is which lowers HbA1c larger in a background of higher baseline HbA1c(>8.5%-9.0%).These findings suggest that the role of DPP-4Is in the management of type 2 diabetes mellitus cannot be completely ignored even in the era of SGLT-2Is.

关键词： DPP-4 inhibitors SGLT-2 inhibitors GLP-1 receptor agonists Cardiovascular outcomes Renal outcomes

Synthetic biology techniques to tackle heavy metal pollution and poisoning

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Synthetic and Systems Biotechnology 2022年第3期7卷 841-846页

作者： Adithi Somayaji Soumodeep Sarkar Shravan Balasubramaniam ritu Raval Department of Biotechnology Manipal Institute of TechnologyManipal Academy of Higher EducationManipalIndia Manipal BioMachines Manipal Institute of TechnologyManipal Academy of Higher EducationManipalIndia

The requirement for natural resources and energy increases continually with the increase in *** inevitable result of this is soil,water,and air pollution with diverse pollutants,including heavy *** Biology involves using modular,interchangeable biological parts,devices in standard chassis or whole organisms to achieve a programmed result that can be quantified and optimized till it meets the required *** makes synthetic biology techniques very popular to tackle pressing global issues such as heavy metal *** review aimed to highlight various advancements as well as benefits,risks,and problems in synthetic biology techniques for detection,bioaccumulation,and biosorption of various heavy metals using engineered *** found that while such an approach is cost-effective,accessible,and efficient,there are several inherent technological and ethical issues including but not limited to metabolic burden and consequences of use of genetically modified organisms *** these hurdles will probably take time and innumerable conversations,and should be done through education and a culture of responsible research,rather than enforcing restrictions on the development of synthetic biology.

关键词： Heavy metals Biosensors Bioremediation Synthetic biology Responsible research