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Modifiable determinants of attitude towards dengue vaccination among healthy inhabitants of Aceh,Indonesia:Findings from a community-based survey

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Asian Pacific Journal of Tropical Medicine 2016年第11期9卷 1092-1098页

作者： Harapan Harapan Samsul Anwar Aslam Bustaman Arsil Radiansyah Pradiba Angraini riny fasli Salwiyadi Salwiyadi Reza Akbar Bastian Ade Oktiviyari Imaduddin Akmal Muhammad Iqbalamin Jamalul Adil Fenni Henrizal Darmayanti Darmayanti Rovy Pratama Jhony Karunia Fajar Abdul Malik Setiawan Mandira Lamichhane Dhimal Ulrich Kuch David Alexander Groneberg R.Tedjo Sasmono Meghnath Dhimal Ruth Mueller Medical Research Unit School of MedicineSyiah Kuala University Tropical Disease Centre School of MedicineSyiah Kuala University Department of Microbiology School of MedicineSyiah Kuala University Department of Statistics Faculty of Mathematics and Natural SciencesSyiah Kuala University Department of Biology Faculty of Teacher Training and EducationSyiah Kuala University Department of Microbiology Faculty of Medicine and Health SciencesState Islamic University Maulana Malik Ibrahim Institute of Occupational Medicine Social Medicine and Environmental MedicineGoethe University Eijkman Institute for Molecular Biology Nepal Health Research Council(NHRC) Ministry of Health Complex

Objective:To explore and understand the attitude towards dengue vaccination and its modifiable determinants among inhabitants of Aceh(northern Sumatra Island,Indonesia),the region that was most severely affected by the earthquake and tsunami of 26 December ***:A communitybased,cross-sectional study was conducted among 535 healthy inhabitants in nine regencies(Kabupaten or Kotamadya) of Aceh that were selected randomly from November 2014 to March 2015.A set of validated,pre-tested,structured questionnaires was used to guide the *** questionnaires covered a range of explanatory variables and one outcome variable(attitude to dengue vaccination).Multi-step logistic regression analysis and Spearman's rank correlation were used to test the role of explanatory variables for the outcome ***:More than 70%of the participants had a poor attitude towards dengue *** determinants associated with poor attitude to dengue vaccination were low education level,working as farmers and traditional market traders,low socioeconomic status and poor knowledge,attitude and practice regarding dengue fever(P<0.05).The KAP domain scores were correlated strongly with attitude to dengue vaccination,r_s=0.25,r_S=0.67 and r_s=0.20,respectively(P<0.001).Multivariate analysis found that independent predictors associated with attitude towards dengue vaccination among study participants were only sex and attitude towards dengue fever(P<0.001).Conclusions:This study reveals that low KAP regarding dengue fever,low education level and low socioeconomic status are associated with a poor attitude towards dengue ***,inhabitants of suburbs who are working as larmers or traditional market traders with low socioeconomic status are the most appropriate target group for a dengue vaccine introduction program.

关键词： Attitude towards vaccination Dengue fever Dengue vaccine Dengue Indonesia Vaccine introduction program

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