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中华医学杂志 2000年第11期80卷 858-859页

作者：纪徐淮许国铭 John Telford 屠振兴丁华杜奕奇李兆申 rino rappukli 第二军医大学长海医院消化内科 IRISResearchCenter IRISResearchCenter ChironVaccinesSiena53100Italy

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Does herbal medicine reduce the risk of hepatocellular carcinoma?

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World Journal of Gastroenterology 2015年第37期21卷 10598-10603页

作者： Yasushi rino Norio Yukawa Naoto Yamamoto Department of Surgery School of Medicine Yokohama City University

Many herbal medicines are effective anti-inflammatory agents and may therefore suppress the development of hepatocellular carcinoma(HCC). Recently, treatment with a single-tablet regimen containing ledipasvir and sofosbuvir resulted in high rates of sustained virologic response among patients with hepatitis C virus genotype1 infection who did not respond to prior interferon-based treatment. Patients with chronic hepatitis C are expected to receive this treatment worldwide. However, many patients have hepatitis-like fatty liver and nonalcoholic steatohepatitis. A strategy to prevent the development of HCC in this subgroup of patients is urgently *** herbal medicines can suppress the development of HCC remains to be established. However, herbal medicines are effective anti-inflammatory agents and may inhibit the development of HCC. Clinical trials exploring the effectiveness of herbal medicines in the prevention and treatment of HCC are therefore warranted. The current lack of knowledge and of educational programs is a barrier to increasing the use of potentially effective herbal medicines and performing prospective clinical trials.

关键词： Herbal medicine Hepatocellular carcinoma Anti-infl

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Double-ejection micro-cathode arc thruster applied to micro-satellite

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High Voltage 2023年第1期8卷 102-110页

作者： Jia Tian Wenzheng Liu Anton Nikiforov Nathalie De Geyter rino Morent School of Electrical Engineering Beijing Jiaotong UniversityBeijingChina Research Unit Plasma Technology(RUPT) Department of Applied PhysicsGhent UniversityGhentBelgium

An innovative double-ejection micro-cathode arc thruster(AC_(d-μ)CAT),which consists of a cylindrical inner anode,a cylindrical outer cathode and two insulating sleeves(an inner insulating sleeve and an outer insulating sleeve),was *** differences in electrical characteristics,plasma parameters and propulsion performance between the newly proposed AC_(d-μ)CAT and a traditionalμCAT were *** results showed that compared to the traditionalμCAT structure,by using the AC_(d-μ)CAT,the peak value of produced thrust was increased 9.3 times,while the amplitude of the ion current and the ion-to-arc ratio were increased 5.4 and 5.9 times(from 1.2%to 7.1%),*** addition,data from Langmuir probe experiments indicated that peak values of the directional propagation speed and density of plasma plume were increased 3.1 times and 4.2 times,***,plasma plume directional ejection performance was also significantly *** study result will provide support for the development of a new-generationμCAT.

关键词： cylindrical inner outer

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Learning from the 2009 H1N1 pandemic:prospects for more broadly effective influenza vaccines

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Journal of Molecular Cell Biology 2011年第3期3卷 144-146页

作者： Ethan C.Settembre Philip R.Dormitzer rino Rappuoli Novartis Vaccines and Diagnostics CambridgeMAUSASienaItaly

Calls to develop a universal influenza vaccine have increased in the wake of the 2009 H1N1 influenza *** demand comes at a time when analyses of the human antibody repertoire,informed by structures of complexes between broadly neutralizing antibodies and influenza hemagglutinin,have revealed the target of a class of broadly neutralizing *** studies suggest a path forward to more broadly protective influenza vaccines.

关键词： influenza vaccines protective

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Early gastric cancer diagnostic ability of ultrathin endoscope loaded with laser light source

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World Journal of Gastroenterology 2019年第11期25卷 1378-1386页

作者： Takuto Suzuki Yoshiyasu Kitagawa rino Nankinzan Taketo Yamaguchi Department of Endoscopy Chiba Cancer Center Department of Gastroenterology Chiba Cancer Center

BACKGROUND Conventionally, the low luminous intensity, low image resolution, and difficulty in operation have been reported with the ultrathin endoscope. However, it has markedly advanced recently. The improvement of the diagnostic ability is *** To compare the early gastric cancer diagnostic ability of an ultrathin endoscope loaded with a laser light source and that of the conventional *** The target subjects were 375 consecutive patients who underwent endoscopy at our hospital for post-endoscopic submucosal dissection follow-up of gastric cancer from January to August 2018. During endoscopy, the ultrathin endoscope was used in 140 patients(37.3%), and the conventional endoscope was used in235 patients(62.7%). Patient background was adjusted using the propensity score matching method, and gastric cancer detection ability was evaluated in the two *** The gastric cancer detection rate was 7.8% in the ultrathin endoscope group and7.0% in the conventional endoscope group, and the mean intragastric observation time was 4.1 ± 1.7 min in the ultrathin endoscope group and 4.1 ± 1.9 min in the conventional endoscope group, showing no significant differences between the groups. Moreover, the biopsy implementation rate was 31.8% in the ultrathin endoscope group and 41.1% in the conventional endoscope group, and the biopsy prediction rate was 17.9% and 13.2%, respectively, showing no significant differences between the *** The gastric cancer diagnostic ability of the ultrathin endoscope loaded with a laser light source was comparable to that of the conventional endoscope. The observation time was also comparable. Thus, endoscopy using the ultrathin endoscope loaded with the laser light source would be the first option in screening examinations of gastric cancer due to its low invasion.

关键词： Conventional endoscope Gastric cancer Laser light source Screening Ultrathin endoscope

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Investigation on removal pathways of Di 2-ethyl hexyl phthalate from synthetic municipal wastewater using a submerged membrane bioreactor

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Journal of Environmental Sciences 2015年第11期27卷 37-50页

作者： Mehdi Zolfaghari Patrick Drogui Brahima Seyhi Satinder Kaur Brar Gerardo Buelna rino Dubé Nouha Klai National Institute of Scientific Research Water Earth and Environment (INRS-ETE) University of Quebec Industrial Research Center of Quebec

Highly hydrophobic Di 2-ethyl hexyl phthalate（DEHP） is one of the most prevalent plasticizers in wastewaters. Since its half-life in biological treatment is around 25 days, it can be used as an efficiency indicator of wastewater treatment plant for the removal of hydrophobic emerging contaminants. In this study, the performance of submerged membrane bioreactor was monitored to understand the effect of DEHP on the growth of aerobic microorganisms. The data showed that the chemical oxygen demand（COD）and ammonia concentration were detected below 10 and 1.0 mg/L, respectively for operating conditions of hydraulic retention time（HRT） = 4 and 6 hr, sludge retention time（SRT） = 140 day and sludge concentration between 11.5 and 15.8 g volatile solid（VS）/L. The removal efficiency of DEHP under these conditions was higher and ranged between 91% and 98%. Results also showed that the removal efficiency of DEHP in biological treatment depended on the concentration of sludge, as adsorption is the main mechanism of its removal. For the submerged membrane bioreactor, the pore size is the pivotal factor for DEHP removal, since it determines the amount of soluble microbial products coming out of the process. Highly assimilated microorganisms increase the biodegradation rate, as 74% of inlet DEHP was biodegraded; however, the concentration of DEHP inside sludge was beyond the discharge limit. Understanding the fate of DEHP in membrane bioreactor,which is one of the most promising and futuristic treatment process could provide replacement for conventional processes to satisfy the future stricter regulations on emerging contaminants.

关键词： Di 2-ethyl hexyl phthalate Submerged membrane bioreactor Removal efficiency Soluble microbial products Toxicity

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Therapeutic interventional endoscopic ultrasound in pancreatobiliary disorders:Does it really replace the surgical/percutaneous approach?

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World Journal of Gastrointestinal Surgery 2021年第6期13卷 537-547页

作者： Cosmas Rinaldi Adithya Lesmana Maria Satya Paramitha rino Alvani Gani Department of Internal Medicine Hepatobiliary DivisionDr.Cipto Mangunkusumo National General HospitalMedical Faculty Universitas IndonesiaJakarta 10430Indonesia Digestive Disease and GI Oncology Center Medistra HospitalJakarta 12950Indonesia

Pancreato-biliary disorders are still incredibly challenging in the field of gastroenterology,as they would sometimes require multi-approach interventional ***,therapeutic interventional endoscopic ultrasound(EUS)has emerged as a potential alternative to surgical or percutaneous ***,considering the high cost of EUS,lack of facility and expertise,most gastroenterologists still often refer cases to undergo surgical interventions without contemplating the possibility of utilizing EUS ***-guided biliary drainage has become one of the best choices for establishing access to biliary system,given the clear visualization of pancreas,gallbladder,and common bile *** there are still only a few studies which directly compare EUSguided and surgical approaches for biliary drainage,current evidence demonstrated the superiority of EUS-guided approach in terms of adverse events and reintervention rates,with similarly high technical and clinical success rates compared to percutaneous and surgical approaches,especially in patients with history of failed endoscopic retrograde cholangiopancreatography *** success rates with shorter length of hospital stay between endoscopic and surgical approaches have also been exhibited for pancreatic pseudocysts and walled-off *** findings about the progress of EUS approach in gastroenterostomy/jejunostomy also indicated a promising potential of EUS,as a less invasive approach,for managing gastric outlet obstruction.

关键词： Pancreato-biliary Endoscopic ultrasound Percutaneous approach Surgical approach Biliary drainage Pancreatic fluid collection

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Hybrid electric discharge plasma technologies for water decontamination:a short review

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Plasma Science and Technology 2019年第4期21卷 1-9页

作者： Kefeng SHANG Jie LI School of Electrical Engineering.Dalian University of Technology.Dalian 116024 People's Republic of China Department of Applied Physics Ghent University.Sint-Pietersnieuwstraat 41 B4.9000 Gent.Belgium

Electric discharge plasma(EDP)can efficiently degrade aqueous pollutants by its in situ gen erated strong oxidative species(OH,0,***)“nd other physiochemical effects(UV irradiation,shockwaves,local high temperature,etc),but a high energy consumptions limit the application of EDP in water *** adsorbents,catalysts,and oxida nts have been employed for en hanci ng the degradation of pollutants by discharge *** hybrid plasma technologies offer improved water treatment performance compared to dischai'ge plasma *** paper reviews the water decontamination performance and mechanisms of these hybrid plasma technologies,and some suggestions on future water treatment technologies based on discharge plasma are also proposed.

关键词： discharge plasma plasma/adsorbent plasma/catalyst plasma/oxidant wastewater decontamination

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Influence of Radial Dimension and Electric Field on a Microwave-Assisted Esterification

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Engineering（科研） 2022年第11期14卷 497-509页

作者： Vittorio Romano rino Apicella Department of Industrial Engineering University of Salerno Fisciano (SA) Italy

Enzymatic synthesis of ethyl hexanoate from hexanoic acid and ethanol in a solvent-free system, carried out at optimum conditions, has been modeled. The process follows a Ping-Pong Bi-Bi reaction rate and it is endothermic, so microwave heating is provided to prevent its shutdown. The mathematical model has been numerically solved with the FEM method. Results show that microwave heating can be successfully used to carry out this kind of reaction.

关键词： Enzymatic Kinetics Microwave Heating FEM

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Commonality： Reproduction of Moral Philosophy in Ethical Decision-Making by Corporate in Indonesia

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Psychology Research 2012年第11期2卷 671-681页

作者： rino Febri Puspitasari STIKOM The London School of Public Relations Jakarta Indonesia Jakarta Indonesia

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