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Seasonal and Spatial Variation of BTEX in Ambient Air of Delhi

Journal of Environmental Protection 2016年第5期7卷 670-688页

作者： rina Singh Manisha Gaur Anuradha Shukla Environmental Science Division CSIR-CRRI New Delhi India Environmental Science Division AcSIR-CRRI New Delhi India

The present study aims to provide an indication of ambient levels of BTEX in the immediate vicinity of petrol filling stations in Delhi & other road side corridors of Delhi. In this study spatial and seasonal variation of BTEX has been measured at different locations in Delhi. For the measurement of VOCs, passive based diffusion methodology was adopted for the adsorption of BTEX over the activated charcoal. Four categories of sampling sites were chosen (residential, traffic junctions, road side corridors and petrol pumps). The result confirms that the aromatic concentrations in the ambient air of gas stations are appreciably higher than the average values in locations with high vehicular flux. The mean concentration of BTEX at all the locations was 0.622μg/m3, 0.361 μg/m3, 1.037 μg/m3 and 0.122 μg/m3. The average concentration of benzene was highest at petrol pump 3.5 μg/m3 however at all other sampling sites it was in the range of 0.294 to 0.712 μg/m3. The mean concentration value shows that the xylene concentration dominates more in Delhi as compared to benzene. The total average BTEX concentration at road side corridors was 0.594 μg.m-3, at residential corridors was 0.262 μg.m-3, at intersections it was 0.649 μg.m-3 and at petrol filling stations it was 1.457 μg.m-3. The concentration was in the order of petrol filling stations > intersections > road side corridors > residence. These data show the predominance of diesel driven vehicles in Delhi since xylene mainly comes from diesel exhausts. The influential VOC species in case of diesel engine exhaust are benzene, ethylbenzene, xylenes, propane, n-decane and undecane and in case of gasoline vehicle exhaust influential species are benzene, ethylbenzene, 1,2,4-methylbenzene, 1,3,5-methylbenzene, n-hexane and 2-methylhexane. So xylene is mainly coming from diesel exhaust since gasoline vehicle exhaust doesn’t show this

关键词： VOCs Benzene Toluene Xylene Ethylbenzene

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Inosine:A broad-spectrum anti-inflammatory against SARS-CoV-2 infection-induced acute lung injury via suppressing TBK1 phosphorylation

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Journal of Pharmaceutical Analysis 2023年第1期13卷 11-23页

作者： Ningning Wang Entao Li Huifang Deng Lanxin Yue Lei Zhou rina Su Baokun He Chengcai Lai Gaofu Li Yuwei Gao Wei Zhou Yue Gao Department of Pharmaceutical Sciences Beijing Institute of Radiation MedicineBeijing100850China Tianjin University of Traditional Chinese Medicine Tianjin301617China Changchun Veterinary Research Institute Chinese Academy of Agricultural SciencesChangchun130122China College of Veterinary Medicine Jilin Agricultural UniversityChangchun130022China Department of Gastroenterology Shanghai General HospitalShanghai Jiao Tong University School of MedicineShanghai200080China

Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)-induced cytokine storms constitute the primary cause of coronavirus disease 19(COVID-19)progression,severity,criticality,and *** and anti-cytokine therapies are frequently administered to treat COVID-19,but have limited clinical efficacy in severe and critical ***,the weaknesses of these treatment modalities have prompted the development of anti-inflammatory therapy against this *** found that the broad-spectrum anti-inflammatory agent inosine downregulated proinflammatory interleukin(IL)-6,upregulated anti-inflammatory IL-10,and ameliorated acute inflammatory lung injury caused by multiple infectious *** significantly improved survival in mice infected with *** indirectly impeded TANK-binding kinase 1(TBK1)phosphorylation by binding stimulator of interferon genes(STING)and glycogen synthase kinase-3β(GSK3β),inhibited the activation and nuclear translocation of the downstream transcription factors interferon regulatory factor(IRF3)and nuclear factor kappa B(NF-κB),and downregulated IL-6 in the sera and lung tissues of mice infected with lipopolysaccharide(LPS),H1N1,or ***,inosine administration is feasible for clinical anti-inflammatory therapy against severe and critical ***,targeting TBK1 is a promising strategy for inhibiting cytokine storms and mitigating acute inflammatory lung injury induced by SARS-CoV-2 and other infectious agents.

关键词： Cytokine stormInterleukin 6 (IL-6)InosineSARS-CoV-2TANK-binding kinase 1 (TBK1)

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创建专项技术创新服务平台提升高职院校社会服务能力的实践研究——以内蒙古机电职业技术学院为例

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创新创业理论研究与实践 2024年第13期7卷 156-158页

作者：吕文春陈金霞乌日娜李晔曹慧包月英内蒙古机电职业技术学院内蒙古呼和浩特010070

该文结合《关于实施中国特色高水平高职学校和专业建设计划的意见》《职业教育提质培优行动计划(2020—2023年)》,依托内蒙古自治区新能源、新材料、节能环保、装备制造等战略性新兴产业,以技术技能积累为纽带,创建集人才培养、团队建... 详细信息

该文结合《关于实施中国特色高水平高职学校和专业建设计划的意见》《职业教育提质培优行动计划(2020—2023年)》,依托内蒙古自治区新能源、新材料、节能环保、装备制造等战略性新兴产业,以技术技能积累为纽带,创建集人才培养、团队建设、技术服务于一体,资源共享、机制灵活、产出高效的专项技术创新服务平台,支撑一批校企、校校合作的专项技术研究室、技术技能大师服务中心推进项目开发和成果转化;服务区域经济发展,全面提升区域贡献度。

关键词：创新平台技术服务信息化体系机制成果转化产教融合

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The biogenic silica variation and paleoproductivity evolution in the eastern Indian Ocean during the past 20 000 a

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Acta Oceanologica Sinica 2019年第1期38卷 78-84页

作者： Yonghang Xu Liang Wang Zhikun Lai Xiaohui Xu Feng Wang Shengfa Liu Xuefa Shi Rainer Arief Troa rina Zuraida Eko Triarso Marfasran Hendrizan Laboratory of Ocean and Coast Geology Third Institute of Oceanography Ministry of Natural Resources Laboratory for Marine Geology Pilot National Laboratory for Marine Science and Technology (Qingdao) Key Laboratory of Marine Sedimentology and Environmental Geology First Institute of Oceanography Ministry of Natural Resources Marine Research Center Agency of Research and Human Resources for Marine and Fisheries Marine Geological Institute Agency for Research and Development for Energy and Mineral Resources Research Center for Geotechnology Indonesia Institute of Sciences

The biogenic silica of sediment samples from Core CJ01-185 which is collected from the eastern India Ocean off the Sunda Strait is analyzed to evaluate the impact of the opening of the Sunda Strait on a paleoproductivity evolution. The new results indicate that the biogenic silica mass values of Core CJ01-185 show the lowest 0.86% in the last glacial period, and reach its maxima of 1.89% in the late Holocene. Furthermore, the biogenic silica mass accumulation rate(MARBSi) values also vary with much higher during the late Holocene than during the last glaciation. The input of additional terrigenous materials from the Java Sea has enhanced the paleoproductivity and increased the biogenic silica mass and MARBSi values after the opening of the Sunda Strait. It is suggested that the paleoproductivity in the study area is mainly influenced by the southeast monsoon and upwelling before the opening of the Sunda Strait. However, the paleoproductivity is dominated by the terrigenous materials input other than by the southeast monsoon or upwelling in the Holocene.

关键词： biogenic silica paleoproductivity Sunda Strait eastern India Ocean

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Quantification of atorvastatin in human plasma by liquid chromatography tandem mass spectrometry and its application for bioequivalence study of three formulations

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Asian Journal of Pharmaceutical Sciences 2016年第1期11卷 66-67页

作者： Yahdiana Harahap Santi Purnasari Harmita rina Rahmawati Krisnasari Dian Pratami Witri Sansris Siti Fatriyah Laboratory of Bioavailability and Bioequivalence Faculty of Pharmacy Universitas Indonesia

Atorvastatin, a chemical ([R-(R*, R*)]-2-(4-fluorophenyl)-b,ddihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]1 H-pyrole-1-heptanoic acid), is a synthetic HMG-Co A (3-hydroxy-3-methylglutaryl-coenzyme A)reductase inhibitor. It has been shown to be remarkably efficacious in decreasing the level of cholesterol and triglyceride(1)In order to quantify the level of atorvastatin in plasma, it needs a sensitive, rapid and selective method.

关键词： Atorvastatin Simvastatin LC-MS/MS

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A neuropsychological evaluation of orthorexia nervosa

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Open Journal of Psychiatry 2013年第2期3卷 214-222页

作者： Nancy S. Koven rina Senbonmatsu Department of Psychology Bates College Maine USA School of Medicine Semmelweis University Budapest Hungary

Orthorexia nervosa (ON) describes a fixation for proper nutrition and healthy foods that leads to die-tary restrictions and nutritional deficiencies over time. Given symptom overlap among ON, obsessive-compulsive disorder (OCD), and anorexia nervosa (AN), this study examines whether ON has a unique neuropsychological profile. Participants completed symptom checklists and neuropsychological tests chosen for their sensitivity to AN and OCD. Results showed that, across the full sample, ON is independently associated with self-reported weaknesses in Set-Shifting, Emotional Control, Self-Monitoring, and Working Memory. After controlling for AN and OCD variables, high- and low-ON groups differed in total correct trials on the Wisconsin Card Sorting Test. These areas of executive functioning, which are explained in the context of ON symptomatology, represent what would be considered the neuropsychological overlap among OCD and AN profiles.

关键词： Orthorexia Nervosa Neuropsychology Executive Function Anorexia Nervosa Obsessive Compulsive Disorder

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Kidney Stones Are Prevalent in Individuals with Pseudoxanthoma Elasticum, a Genetic Ectopic Mineralization Disorder

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International Journal of Dermatology and Venereology 2020年第4期3卷 198-204页

作者： Ralph Douglas Allawh rina Terry Ian F. Terry Sharon F. Uitto Jouni Li Qiao-Li Department of Dermatology and Cutaneous Biology The Sidney Kimmel Medical Collegeand The PXE International Center of Excellence in Research and Clinical CareThomas Jefferson UniversityPhiladelphiaPA 19107USA PXE International Inc.WashingtonDC 20008USA Jefferson Institute of Molecular Medicine Thomas Jefferson UniversityPhiladelphiaPA 19107USA

Objective:Pseudoxanthoma elasticum(PXE)is a rare genetic disorder caused by loss-of-function mutations in the ABCC6 *** PXE is characterized by ectopic mineralization of connective tissues clinically affecting the skin,eyes,and cardiovascular system,kidney stones were reported in some individuals with *** aim of this study is to determine whether kidney stones are an incidental finding or a frequent manifestation of ***:We first investigated the genetic basis of two siblings diagnosed with *** younger patient presented with recurrent kidney stones since 8 years ***,to address whether kidney stones are associated with PXE,the prevalence of kidney stones in a survey cohort of 563 respondents with PXE was compared to that of a general *** survey,National Health and Nutrition Examination Survey,with 28,629 ***:Genetic analysis in both patients identified compound heterozygous mutations in ABCC6,c.2787+1G>T,and c.3774_*** analysis of participants 20 years old and older revealed that 23.4%of PXE patients had previously had a kidney stone,a significant increase compared to 9.2%in the general population(P<0.01).In addition,17.8%of PXE patients reported their first kidney stone episode before age of 18 years ***:PXE correlates with an increased risk of developing kidney stones with considerable morbidity and health-care cost.

关键词： ectopic mineralization kidney stones pseudoxanthoma elasticum

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健脾五味丸HPLC指纹图谱的建立及多指标成分的含量测定研究

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现代中药研究与实践 2024年第3期38卷 47-51页

作者：张玉婷莎日娜王焕芸何春龙张屏孙丽君内蒙古医科大学药学院内蒙古呼和浩特010110 内蒙古医科大学第二附属医院内蒙古呼和浩特手010110

目的建立蒙药健脾五味丸指纹图谱和多指标含量测定方法,为其质量控制提供依据。方法采用Sepax HP-C_(18)(4.6 mm × 250 mm,5 μm)色谱柱,乙腈-0.1%甲酸溶液为流动相,梯度洗脱,流速为1 mL/min,检测波长为254 nm,柱温为28 ℃,进样量为... 详细信息

目的建立蒙药健脾五味丸指纹图谱和多指标含量测定方法,为其质量控制提供依据。方法采用Sepax HP-C_(18)(4.6 mm × 250 mm,5 μm)色谱柱,乙腈-0.1%甲酸溶液为流动相,梯度洗脱,流速为1 mL/min,检测波长为254 nm,柱温为28 ℃,进样量为10 μL;建立10 批健脾五味丸的指纹图谱,并采用一测多评法测定其中7种成分的含量。结果健脾五味丸HPLC指纹图谱确定了11个共有峰,指认出原儿茶酸、没食子酸、胡黄连苷Ⅰ、胡黄连苷Ⅱ、鞣花酸、土木香内酯和异土木香内酯7个成分,通过一测多评法计算得到7个成分的含量值,与外标法比较10 批样品含量测定结果一致。经方法学验证,线性关系良好(r ≥ 0.999),加样回收率为96.68% ~ 104.44%。结论所建立的指纹图谱和多指标含量测定方法准确、高效、特征性强,可为健脾五味丸的质量评价和临床应用提供参考。

关键词：健脾五味丸指纹图谱一测多评法高效液相色谱法

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超声弹性成像诊断儿童慢性肝病研究进展

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中国医学影像技术 2024年第3期40卷 464-467页

作者：许凤麟张琪李日娜王偲蕴胡彩辉余明珠陈镜宇重庆医科大学附属儿童医院超声科国家儿童健康与疾病临床医学研究中心儿童发育疾病研究教育部重点实验室儿科学重庆市重点实验室重庆400014 富士胶片医疗系统(广州)有限公司北京分公司北京100006 重庆医科大学第二临床学院重庆400016

儿童慢性肝病可致肝纤维化、炎症及脂肪变性等。近年兴起的超声弹性成像新技术可为诊断儿童慢性肝病提供新思路。本文就超声弹性成像用于诊断儿童慢性肝病研究进展进行综述。

关键词：儿童肝疾病超声检查弹性成像技术

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内蒙古通辽市全株青贮玉米发展现状分析

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养殖与饲料 2024年第6期23卷 41-44页

作者：张超刘涵淼李雅剑塔娜王琦萨日娜贾兴田王丹通辽市农牧科学研究所内蒙古通辽028015

[目的]为了了解通辽市全株青贮玉米产业发展现状,寻找发展中存在的问题,并提出解决方案,促进通辽市全株青贮玉米产业的高质量发展。[方法]通过查阅相关文献和资料,对通辽市青贮玉米发展现状以及存在的问题进行分析和思考。[结果]近年来... 详细信息

[目的]为了了解通辽市全株青贮玉米产业发展现状,寻找发展中存在的问题,并提出解决方案,促进通辽市全株青贮玉米产业的高质量发展。[方法]通过查阅相关文献和资料,对通辽市青贮玉米发展现状以及存在的问题进行分析和思考。[结果]近年来,通辽市虽然根据国家“粮改饲”产业布局调整政策,大力发展青贮玉米产业,但是在产业规模上、生产效率上、技术配套上还存在很多不足。[结论]要高质量发展通辽市全株青贮玉米产业,就要逐步建立种销结合的合作格局,加大全株青贮玉米新品种和新技术的研发,全方位推进玉米全株青贮的机械化收获技术以及加大青贮玉米产业扶持力度。

关键词：全株青贮玉米发展现状对策建议通辽市粮改饲青贮机械装备

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