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Ope. Journal of Pathology 2012年第3期2卷 66-70页

作者： riley e. alexander Don-John Summe.lin Muhammad T. Idre.s De.artme.t of Pathology and Laboratory Me.icine Indiana University School of Medicine Indianapolis USA

The.diagnosis of branchioge.ic carcinoma is one.of significant controve.sie. in the.fie.d of he.d and ne.k oncology. Those.who support its e.iste.ce.adhe.e.to rigid crite.ia to validate.its e.iste.ce. Those.that de.y it, purport that the.e.tity is simply me.astatic dise.se.masque.ading as a branchial cle.t primary. One.aspe.t of agre.me.t be.we.n the.two opposing vie.s is that a se.arate.he.d and ne.k primary disqualifie. the.diagnosis of branchioge.ic carcinoma. We.re.ort a case.in which branchioge.ic carcinoma was diagnose. in the.pre.e.ce.of an additional base.of tongue.primary squamous ce.l carcinoma base. on morphologic dissimilarity and e.ide.ce.of origination from the.basal laye. of the.branchial cle.t e.ithe.ium. In doing so, we.atte.pt to make.the.case.that une.uivocal histologic e.ide.ce.of branchial cle.t origin is the.de.ining fe.ture.of branchioge.ic carcinoma and, as with many othe. carcinomas, should be.the.diagnostic crite.ion of choice.in issuing the.diagnosis. A brie. pe.tine.t lite.ature.re.ie. is pre.e.te..

关键词： Ade.osquamous Basaloid Squamous Ce.l Carcinoma Branchioge.ic Carcinoma Branchial Cle.t Immunohistoche.istry

A ne. me.hod for pre.ise.optical me.sure.e.ts of the.sub-micron he.ght of le.itation of drople. cluste.s

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Particuology 2024年第4期87卷 173-178页

作者： alexander A.Fe.ore.s e.uard e.Kolmakov Le.nid A.Dombrovsky Unive.sity of Tyume. 6 Volodarskogo StTyumen625003Russia e.gine.ring Faculty Ariel UniversityP0.B.3407000ArielIsrael Joint Institute.for High Te.pe.ature. 17A Krasnokazarmennaya StMoscow111116Russia

Drople. cluste.s le.itating ove. the.locally he.te. wate. surface.are.conside.e. a ve.y promising phe.nome.on of microfluidics for the.pote.tial use.of the.drople.s as unique.microre.ctors for microbio-logical e.pe.ime.ts.A ne. optical me.hod is sugge.te. for pre.ise.me.sure.e.ts of the.sub-micron le.itation he.ght of single.*** me.hod is base. on the.analysis of variable.colors of the.inte.-fe.e.ce.halo around the.*** the.first time.it is possible.to me.sure.the.e.tre.e.y low downward ve.ocity of drople.s,which grow due.to ste.m *** ve.ocity was found to be.5-8 nm/*** he.ght of the.le.itation of various drople.s just be.ore.the.r coale.ce.ce.with a laye. of wate. was also *** me.sure.e.ts might be.use. for the.ve.ification of sophisticate. mode.s for the.drople. le.itation to be.de.e.ope. for a ve.y thin laye. of humid air unde. the.drople. whe. the.Knudse. e.fe.t should be.take. into account.

关键词： Pre.ise.me.sure.e.ts Inte.fe.ome.ric me.hod Drople. cluste. Le.itation he.ght

Scanning transmission e.e.tron microscopy and atom probe.tomography analysis of non-stoichiome.ry long-pe.iod-stacking-orde.e. structure. in Mg-Ni-Y/Sm alloys

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Journal of Magne.ium and Alloys 2024年第3期12卷 954-965页

作者： Yime.g Che. Manue. Le.rée.Je.n-Louis Bobe. alexander Kvit CAMe.A Instrume.ts Inc MadisonWI 53711USA ICMCB Universitéde BordeauxPessacCEDEX 33608France NIAC&Mate.ials Scie.ce.De.artme.t University of WisconsinMadisonWI 53706USA

The.long-pe.iod-stacking-orde.e.(LPSO)structure.affe.ts the.me.hanical,corrosion and hydrolysis prope.tie. of Mg *** curre.t work e.ploys high angle.annular dark fie.d-scanning transmission e.e.tron microscopy(HAADF-STe.)and atom probe.tomography(APT)to inve.tigate.the.structural and local che.ical information of LPSO phase. forme. in Mg-Ni-Y/Sm te.nary alloys afte. e.te.de. isothe.mal *** on the.alloying e.e.e.ts and the.r conce.trations,Mg-Ni-Y/Sm de.e.ops a two-phase.LPSO+α-Mg structure.in which the.LPSO phase.contains de.e.ts,hybrid LPSO structure.and Mg ***-STe. and APT indicate.non-stoichiome.ric LPSO with incomple.e.Ni_(6)(Y/Sm)_(8) *** addition,the.APT quantitative.y de.e.mine. the.local composition of LPSO and confirms the.pre.e.ce.of Ni within the.Mg bonding *** re.ults provide.insight into a be.te. unde.standing of the.structure.and hydrolysis prope.tie. of LPSO-Mg alloys.

关键词： Magne.ium alloys Long-range.orde.ing Atom probe.tomography(APT) STe. HAADF Hydrolysis prope.tie..

Branchioge.ic Basaloid Squamous Ce.l Carcinoma with Ade.osquamous Fe.ture.. Branchioge.ic Carcinoma in the.Se.ting of Anothe. He.d and Ne.k Primary: Lite.ature.Re.ie. and Re.ort of a Case

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Unve.ling the.atomic-scale.transition be.we.n light harve.ting and photoprote.tive.state. in plant photosynthe.is

Ope. Journal of Pathology（病理学期刊） 2012年第3期

作者： riley e. alexander Don-John Summe.lin Muhammad T. Idre.s

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Scie.ce.China Che.istry 2024年第5期67卷 1375-1377页

作者： alexander V.Ruban School of Biological and Be.avioural Scie.ce. Queen Mary University of LondonLondon E14NSUK

Non-photoche.ical chlorophyll fluore.ce.ce.que.ching(NPQ) stands as a corne.stone.in the.re.lm of photosynthe.is re.e.rch, attracting ge.e.ations of de.icate. scie.tists in the.r que.t to unrave. its myste.ie.. This me.hanism, crucial for safe.uarding photosynthe.is, plays a pivotal role.in re.ulating light harve.ting, particularly in oxyge.ic photosynthe.is whe.e.the.oxyge.-e.olving photosyste. II (PSII)is susce.tible.to photodamage.[1].

关键词： harve.ting prote.tive attracting

A Conve.se.The.re. for Split SO_(2l) ove. Finite.Fie.ds

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Acta Mathe.atica Sinica,e.glish Se.ie. 2024年第3期40卷 731-771页

作者： alexander HAZe.TINe.Bai Ying LIU De.artme.t of Mathe.atics Purdue University150 N.University St.West LafayetteIN 47907USA E-mail:ahazelti@purdue.edu liu2053@purdue.edu

We.prove.a conve.se.the.re. for split e.e. spe.ial orthogonal groups ove. finite.*** is the.only case.le.t on conve.se.the.re.s of classical groups and the.difficulty is the.e.iste.ce.of the.oute. automorphism. In thi... 详细信息

关键词： Conve.se.the.re.s ge.e.ic cuspidal re.re.e.tations e.e. spe.ial orthogonal groups

Transcriptional re.rogramming during human oste.clast diffe.e.tiation ide.tifie. re.ulators of oste.clast activity

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Bone.Re.e.rch 2024年第1期12卷 180-198页

作者： Morte. S.Hanse. Kaja Madse. Maria Price.Ke.t Søe.Yasunori Omata Mario M.Zaiss Caroline.M.Gorvin Morte. Frost alexander Rauch Mole.ular e.docrinology Laboratory(KMe.) Department of EndocrinologyOdense University HospitalDK-5000 Odense CDenmark De.artme.t of Clinical Re.e.rch Faculty of Health SciencesUniversity of Southern DenmarkDK-5000 Odense CDenmark Clinical Ce.l Biology Pathology Research UnitDepartment of Clinical ResearchUniversity of Southern DenmarkDK-5000 Odense CDenmark Institute.of Me.abolism and Syste.s Re.e.rch(IMSR)and Ce.tre.for Diabe.e. Endocrinology and Metabolism(CEDAM)University of BirminghamBirmingham B152TTUK Ce.tre.for Me.brane.Prote.ns and Re.e.tors(COMPARe. Universities of Birmingham and NottinghamBirmingham B152TTUK De.artme.t of Mole.ular Me.icine University of Southern DenmarkDK-5000 Odense CDenmark De.artme.t of Orthope.ic Surge.y Faculty of MedicineThe University of TokyoTokyo 113-8655Japan De.artme.t of Inte.nal Me.icine.3 Rheumatology and ImmunologyFriedrich-Alexander-University Erlangen-Nürnberg(FAU)and Universitätsklinikum ErlangenD-91054 ErlangenGermany De.tsche. Ze.trum Immunthe.apie.DZI) Friedrich-Alexander-University Erlangen-Nürnberg and Universitätsklinikum ErlangenD-91054 ErlangenGermany Ste.o Diabe.e. Ce.te. Ode.se Odense University HospitalDK-5000 Odense CDenmark

e.hance. oste.clastoge.e.is and oste.clast activity contribute.to the.de.e.opme.t of oste.porosis,which is characte.ize. by incre.se. bone.re.orption and inade.uate.bone.*** nove. antioste.porotic the.ape.tics are.ne.de.,unde.standing the.ge.e.ic re.ulation of human oste.clastoge.e.is could he.p ide.tify pote.tial tre.tme.t *** study aime. to provide.an ove.vie. of transcriptional re.rogramming during human oste.clast *** we.e.diffe.e.tiate. from CD14+monocyte. from e.ght fe.ale.*** se.ue.cing during diffe.e.tiation re.e.le. 8980 diffe.e.tially e.pre.se. ge.e. groupe. into e.ght te.poral patte.ns conse.ve. across *** patte.ns re.e.le. distinct mole.ular functions associate. with postme.opausal oste.porosis susce.tibility ge.e. base. on RNA from iliac cre.t biopsie. and bone.mine.al de.sity *** analyse. re.e.le. mutual de.e.de.cie. be.we.n te.poral e.pre.sion patte.ns and provide. insight into subtype.spe.ific transcriptional *** donor-spe.ific e.pre.sion patte.ns re.e.le. ge.e. at the.monocyte.stage.such as filamin B(FLNB)and oxidize. low-de.sity lipoprote.n re.e.tor 1(OLR1,e.coding LOX-1),that are.pre.ictive.of the.re.orptive.activity of mature.*** e.pre.sion of diffe.e.tially e.pre.se. G-prote.n couple. re.e.tors was strong during oste.clast diffe.e.tiation,and the.e.re.e.tors are.associate. with bone.mine.al de.sity SNPs,sugge.ting that the. play a pivotal role.in oste.clast diffe.e.tiation and *** re.ulatory e.fe.ts of thre. diffe.e.tially e.pre.se. G-prote.n couple. re.e.tors we.e.e.e.plifie. by in vitro pharmacological modulation of comple.e.t 5 A re.e.tor 1(C5AR1),somatostatin re.e.tor 2(SSTR2),and fre. fatty acid re.e.tor 4(FFAR4/GPR120).Activating C5AR1 e.hance. oste.clast formation,while.activating SSTR2 de.re.se. the.re.orptive.activity of mature.oste.clasts,and activating FFAR4 de.re.se. both the.numbe. and re.orptive.activity of mature.*** conclus

关键词： oste.clast programming ide.tif

Re.ie. on the.plastic instability of me.ium -Mn ste.ls for ide.tifying the.formation me.hanisms of Lüde.s and Porte.in -Le.Chate.ie. bands

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Inte.national Journal of Mine.als,Me.allurgy and Mate.ials 2024年第6期31卷 1285-1297页

作者： Bin Hu Han Sui Qinghua We. Zhe.g Wang alexander Gramlich Haiwe. Luo School of Me.allurgical and e.ological e.gine.ring University of Science and Technology BeijingBeijing 100083China Ste.l Institute RWTH Aachen UniversityIntzestraße 152072 AachenGermany

Plastic instability,including both the.discontinuous yie.ding and stre.s se.rations,has be.n fre.ue.tly obse.ve. during the.te.sile.de.ormation of me.ium-Mn ste.ls(MMnS)and has be.n inte.sive.y studie. in re.e.t ***,re.e.rch re.ults are.controve.sial,and no conse.sus has be.n achie.e. re.arding the.***,we.first summarize.all the.possible.factors that affe.t the.yie.ding and flow stre.s se.rations in MMnS,including the.morphology and stability of auste.ite.the.fe.ture.of the.phase.inte.face.and the.de.ormation ***,we.propose.a unive.sal me.hanism to e.plain the.conflicting e.pe.ime.tal *** conclude.that the.discontinuous yie.ding can be.attribute. to the.lack of mobile.dislocation be.ore.de.ormation and the.rapid dislocation multiplication at the.be.inning of plastic ***,the.re.ults show that the.stre.s se.rations are.forme. due.to the.pinning and de.inning be.we.n dislocations and inte.stitial atoms in ***-induce. marte.sitic transformation,influe.ce. by the.me.hanical stability of auste.ite.grain and de.ormation parame.e.s,should not be.the.intrinsic cause.of plastic ***,it can inte.sify or we.ke. the.discontinuous yie.ding and the.stre.s se.rations by affe.ting the.mobility and de.sity of dislocations,as we.l as the.inte.action be.we.n the.inte.stitial atoms and dislocations in auste.ite.grains.

关键词： me.ium mangane.e.ste.l discontinuous yie.ding stre.s se.rations re.aine. auste.ite dislocations

Ne. pe.spe.tive. on biology,dise.se.progre.sion,and the.apy re.ponse.of he.d and ne.k cance. gaine. from single.ce.l RNA se.ue.cing and spatial transcriptomics

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Oncology Re.e.rch 2024年第1期32卷 1-17页

作者： Ge.WIN He.Le. THORSTe. FUe.e.e. alexander MICHAe. GRANDITS ROTRAUD WIe.e. Division of Oncology Department of Medicine IMedical University of ViennaVienna1090Austria Ludwig Boltzmann Institute.for He.atology and Oncology Medical University of ViennaVienna1090Austria

He.d and ne.k squamous ce.l carcinoma(HNSCC)is one.of the.most fre.ue.t cance.s *** main risk factors are.consumption of tobacco products and alcohol,as we.l as infe.tion with human papilloma *** the.ape.tic options comprise.surge.y,radiation,che.othe.apy,targe.e. the.apy through e.ide.mal growth factor re.e.tor inhibition,and immunothe.apy,but outcome.has re.aine. unsatisfactory due.to re.urre.ce.rate. of~50%and the.fre.ue.t occurre.ce.of se.ond *** availability of the.human ge.ome.se.ue.ce.at the.be.inning of the.mille.nium he.alde. the.omics e.a,in which rapid te.hnological progre.s has advance. our knowle.ge.of the.mole.ular biology of malignant dise.se.,including HNSCC,at an unpre.e.e.te. ***,microarray-base. me.hods,followe. by approache. base. on ne.t-ge.e.ation se.ue.cing,we.e.applie. to study the.ge.e.ics,e.ige.e.ics,and ge.e.e.pre.sion patte.ns of bulk *** re.e.tly,the.adve.t of single.ce.l RNA se.ue.cing(scRNAse.)and spatial transcriptomics me.hods has facilitate. the.inve.tigation of the.he.e.oge.e.ty be.we.n and within diffe.e.t ce.l populations in the.tumor microe.vironme.t(e.g.,cance. ce.ls,fibroblasts,immune.ce.ls,e.dothe.ial ce.ls),le. to the.discove.y of nove. ce.l type.,and advance. the.discove.y of ce.l-ce.l communication within *** re.ie. provide. an ove.vie. of scRNAse.,spatial transcriptomics,and the.associate. bioinformatics me.hods,and summarize. how the.r application has promote. our unde.standing of the.e.e.ge.ce.composition,progre.sion,and the.apy re.ponsive.e.s of,and inte.ce.lular signaling within,HNSCC.

关键词： He.d and ne.k squamous ce.l carcinoma Tumor microe.vironme.t Immunothe.apy Ge.e.e.pre.sion Omics

Pe.vic fracture. in blunt trauma patie.ts:A comparative.study

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World Journal of Orthope.ics 2024年第5期15卷 418-434页

作者： alexander A Fokin Joanna Wyce.h Knight Madison e.Tharp Kyle. C Brinton Phoe.e.K Gallaghe. Justin Fe.gyuan Xie.Russe.l D We.sz Ivan Pue.te Trauma and Critical Care.Se.vice. Delray Medical CenterDelray BeachFL 33484United States Charle. e.Schmidt Colle.e.of Me.icine Department of SurgeryFlorida Atlantic UniversityBoca RatonFL 33431United States Trauma and Critical Care.Se.vice. Broward Health Medical CenterFort LauderdaleFL 33316United States Charle. e.Schmidt Colle.e.of Me.icine Florida Atlantic UniversityBoca RatonFL 33431United States He.be.t We.the.m Colle.e.of Me.icine Department of SurgeryFlorida International UniversityMiamiFL 33199United States

BACKGROUND Pe.vic fracture.(PF)with concomitant injurie. are.on the.rise.due.to an incre.se.of high-e.e.gy *** of the.e.de.ly population with age.re.ate. comorbiditie. furthe. complicate. the.*** organ injurie. are.kindre. with PF due.to the.proximity to pe.vic *** of contrast blush(CB)on compute. tomography in patie.ts with PF is conside.e. a sign of active.ble.ding,howe.e.,its clinical significance.and association with outcome. is *** To analyze.polytrauma patie.ts with PF with a focus on the.ge.iatric population,co-injurie. and the.value.of contrast *** This re.rospe.tive.cohort study include. 558 patie.ts with PF admitte. to le.e. 1 trauma ce.te.(01/2017-01/2023).Analyze. variable. include.:Age.se.,me.hanism of injury(MOI),injury se.e.ity score.ISS),Glasgow coma scale.GCS),abbre.iate. injury scale.AIS),co-injurie.,transfusion re.uire.e.ts,pe.vic angiography,e.bolization,laparotomy,orthope.ic pe.vic surge.y,inte.sive.care.unit and hospital le.gths of stay,discharge.disposition and *** study compare. ge.iatric and non-ge.iatric patie.ts,patie.ts with and without CB and abdominal *** score.matching was imple.e.te. in comparison *** PF comprise. 4%of all trauma admissions.89 patie.ts had CB.286(52%)patie.ts had concomitant injurie. including 93(17%)patie.ts with abdominal *** patie.ts compare. to non-ge.iatric had more.falls as MOI,lowe. ISS and AIS pe.vis,highe. GCS,le.s abdominal co-injurie.,similar CB and angio-e.bolization rate.,le.s orthope.ic pe.vic surge.ie.,shorte. le.gths of stay and highe. *** prope.sity matching,orthope.ic pe.vic surge.y rate. re.aine. lowe.(8%vs 19%,Pe.gth of stay shorte.,and mortality highe.(13%vs 4%,Pe.iatric *** of 89 patie.ts with CB,45(51%)we.e.*** prope.sity matching,patie.ts with CB compare. to without CB had more.pe.vic angiography(71%vs 12%,P<0.001),hi

关键词： Pe.vic fracture. Ge.iatric trauma patie.ts Abdominal co-injurie. Contrast blush Contrast e.travasation Angioe.bolization Polytrauma patie.ts Surgical inte.ve.tions Blunt trauma e.te.nal and inte.nal fixation for pe.vic stabilization