检索结果-南通市图书馆

Dual-Fields Rotational Total Skin Electron Therapy: Investigation and Implementation

International Journal of medical Physics, Clinical Engineering and Radiation Oncology 2024年第1期13卷 1-15页

作者： m. ming Xu Iris Rusu richard P. Garza Northwestern medicine Cancer Center Warrenville and Geneva Illinois USA Department of Radiation Oncology Loyola University Medical Center Maywood Illinois USA The Austin Center for Radiation Oncology Austin Texas USA

Purpose: To present a protocol of a dual-field rotational (DFR) total skin electron therapy (TSET) and to provide an assessment of clinical implementation, dosimetry properties, and skin dose evaluation. methods and materials: The DFR-TSET combined the Stanford 6-field and mcGill rotational methods. Dual 6 meV electron beams in high dose total skin electron mode were used for DFR-TSET on a commercial linac. Beam profiles and dosimetric properties were measured using solid phantoms. The dose rate at expanded source-to-surface distance (SSD) was a combination of static rate and rotational rate. In vivo dosimetry of patient skin was performed on patients’ skin using film, metal oxide semiconductor field-effect transistors (mOSFET), and optically stimulated luminescent dosimeters (OSLD). Results: Dual field rotational total skin electron therapy exhibited good (≤±10%) uniformity in the beam profiles in the vertical direction at an extended SSD of 332 cm with a gantry angulation of ±20˚ deviated from the horizontal direction. In-vivo measurements confirmed acceptable uniformity of the patients’ total body surfaces and revealed anatomically self-blocked or shielded areas where underdosing occurred. Conclusions: The clinical implementation of DFR-TSET effectively utilizes the special mode on a linac. This technique provides short beam-on times, uniform dose distribution, large treatment field, and reduced dose of x-ray contamination to the patients. In-vivo measurements indicate satisfactory delivery and dose uniformity of the prescribed dose. Electron boost fields are recommended at normal SSDs to address underdosed areas.

关键词： Total Skin Electron Therapy Stanford 6 Field mcGill Rotation Therapy In-Vivo Dosimetry

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

COVID-19 vaccination produces exercise-responsive SARS-CoV-2 specific T-cells regardless of infection history

引用

Journal of Sport and Health Science 2024年第1期13卷 99-107页

作者： Kyle A.Smith Tiffany m.Zúñiga Forrest L.Baker Helena Batatinha Charles R.Pedlar Shane C.Burgess michael P.Gustafson Emmanuel Katsanis richard J.Simpson School of Nutritional Sciences and Wellness The University of ArizonaTucsonAZ 85721USA Department of Pediatrics The University of ArizonaTucsonAZ 85724USA Faculty of Sport Allied Health and Performance ScienceSt.Mary's UniversityTwickenham TW14SXUK Institute of Sport Exercise and Health University College LondonLondon WC1E 7HUUK Department of Animal and Comparative Biomedical Sciences The University of ArizonaTucsonAZ 85721USA The University of Arizona Cancer Center The University of ArizonaTucsonAZ 85719USA Laboratory medicine and Pathology Mayo Clinic ArizonaPhoenixAZ 85054USA Department of Immunobiology The University of ArizonaTucsonAZ 85724USA Department of medicine The University of ArizonaTucsonAZ 85724USA Department of Pathology The University of ArizonaTucsonAZ 85724USA

Background:The mobilization and redistribution of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)specific T-cells and neutralizing antibodies(nAbs)during exercise is purported to increase immune surveillance and protect against severe coronavirus disease 2019(COVID-19).We sought to determine if COVID-19 vaccination would elicit exercise-responsive SARS-CoV-2 T-cells and transiently alter nAb ***:Eighteen healthy participants completed a 20-min bout of graded cycling exercise before and/or after receiving a COVID-19 *** major leukocyte subtypes were enumerated before,during,and after exercise by flow cytometry,and immune responses to SARS-CoV-2 were determined using whole blood peptide stimulation assays,T-cell receptor(TCR)-βsequencing,and SARS-CoV-2 nAb ***:COVID-19 vaccination had no effect on the mobilization or egress of major leukocyte subsets in response to intensity-controlled graded ***,non-infected participants had a significantly reduced mobilization of CD4+and CD8+naive T-cells,as well as CD4+central memory T-cells,after vaccination(synthetic immunity group);this was not seen after vaccination in those with prior SARS-CoV-2 infection(hybrid immunity group).Acute exercise after vaccination robustly mobilized SARS-CoV-2 specific T-cells to blood in an intensity-dependent *** groups mobilized T-cells that reacted to spike protein;however,only the hybrid immunity group mobilized T-cells that reacted to membrane and nucleocapsid *** increased significantly during exercise only in the hybrid immunity ***:These data indicate that acute exercise mobilizes SARS-CoV-2 specific T-cells that recognize spike protein and increases the redistribution of nAbs in individuals with hybrid immunity.

关键词： Anti-viral COVID-19 Exercise immunology SARS-CoV-2 T-Cells Vaccine

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

mollisols Properties and Changes in Ukraine and China

引用

Chinese Geographical Science 2011年第3期21卷 257-266页

作者： Yuri S KRAVCHENKO ZHANG Xingyi LIU Xiaobing SONG Chunyu richard m.cruse Key Laboratory of mollisols Agroecology Northeast Institute of Geography and Agroecology Chinese Academy of Sciences Harbin 150081 China National University of Life and Environmental Sciences of Ukraine Kyiv 03041 Ukraine Department of Agronomy Iowa State University Ames 500011 IA USA

Soils are the foundation of civilizations and the basis for human food *** in Ukraine and Northeast China are two out of the four major mollisol regions in the *** natural areas from which mollisols developed are the prairies and steppes that experience temperate and freezing *** review paper introduces the general climate,vegetation,and topography of mollisols regions in Ukraine and Northeast China,analyzes their properties,including soil texture,soil organic matter content,soil bulk density,pH,cation exchange capacity and other chemical properties,and compares the property changes and management practices of mollisols in relation to sustainable grain production.

关键词： mollisols soil properties soil organic matter tillage mollisols management

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Beyond cotton and polyester: An evaluation of emerging feedstocks and conversion methods for the future of fashion industry

引用

Journal of Bioresources and Bioproducts 2024年第2期9卷 130-159页

作者： Ryen m.Frazier Keren A.Vivas Ivana Azuaje Ramon Vera Alonzo Pifano Naycari Forfora Hasan Jameel Ericka Ford Joel J.Pawlak richard Venditti Ronalds Gonzalez Department of Forest Biomaterials North Carolina State UniversityRaleighNC 27695USA Department of Textile Engineering Chemistry and ScienceThe Nonwovens InstituteNorth Carolina State UniversityRaleighNC 27695USA

As the global population grows,the demand for textiles is increasing ***,this puts immense pressure on manufacturers to produce more *** synthetic fibers can be pro-duced cheaply,they have a negative impact on the *** the other hand,fibers from wool,sisal,fique,wood pulp(viscose),and man-made cellulose fibers(mmCFs)from cotton can-not alone meet the growing fiber demand without major stresses on land,water,and existing markets using these *** a greater emphasis on transparency and circular economy practices,there is a need to consider natural non-wood alternative sources for mmCFs to supple-ment other fiber ***,introducing new feedstocks with different compositions may require different biomass conversion ***,based on existing work,this review ad-dresses the technical feasibility of various alternative feedstocks for conversion to textile-grade ***,alternative feedstocks are introduced,and then conventional(dissolving pulp)and emerging(fibrillated cellulose and recycled material)conversion technologies are evaluated to help select the most suitable and promising processes for these emerging alternative sources of *** is important to note that for alternative feedstocks to be adopted on a meaningful scale,high biomass availability and proximity of conversion facilities are critical *** North America,soybean,wheat,rice,sorghum,and sugarcane residues are widely available and most suitable for conventional conversion through various dissolving pulp production methods(pre-hydrolysis kraft,acid sulfite,soda,SO2-ethanol-water,and potassium hydroxide)or by emerging cellulose fibrillation *** dissolving pulp conversion is well-established,fibrillated cel-lulose methods could be beneficial from cost,efficiency,and environmental ***,the authors strongly encourage more work in this growing research ***,conducting thorough cost and sustainability assessment

关键词： Non-wood Residue Regenerated cellulose Dissolving pulp man-made cellulose fiber Apparel textile

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

CD8+T cell metabolic flexibility elicited by CD28-ARS2 axisdriven alternative splicing of PKm supports antitumor immunity

引用

Cellular & molecular Immunology 2024年第3期21卷 260-274页

作者： G.Aaron Holling Colin A.Chavel Anand P.Sharda mackenzie m.Lieberman Caitlin m.James Shivana m.Lightman Jason H.Tong Guanxi Qiao Tiffany R.Emmons Thejaswini Giridharan Shengqi Hou Andrew m.Intlekofer richard m.Higashi Teresa W.m.Fan Andrew N.Lane Kevin H.Eng Brahm H.Segal Elizabeth A.Repasky Kelvin P.Lee Scott H.Olejniczak Department of Immunology Roswell Park Comprehensive Cancer CenterBuffaloNY 14263USA Department of medicine Roswell Park Comprehensive Cancer CenterBuffaloNY 14263USA Human Oncology and Pathogenesis Program Memorial Sloan Kettering Cancer CenterNew YorkNY 10065USA Center for Environmental Systems Biochemistry Department of Toxicology and Cancer Biology and Markey Cancer CenterLexingtonKY 40536USA Department of Cancer Genetics and Genomics Roswell Park Comprehensive Cancer CenterBuffaloNY 14263USA Present address:University of Colorado Boulder BoulderCO 80309USA Present address:Dana Farber Cancer Institute BostonMA 02215USA Present address:massachusetts Institute of Technology BostonMA 02139USA Present address:melvin and Bren Simon Comprehensive Cancer Center Indiana University School of MedicineIndianapolisIN 46202USA

metabolic flexibility has emerged as a critical determinant of CD8+T-cell antitumor activity,yet the mechanisms driving the metabolic flexibility of T cells have not been *** this study,we investigated the influence of the nuclear cap-binding complex(CBC)adaptor protein ARS2 on mature T *** doing so,we discovered a novel signaling axis that endows activated CD8+T cells with flexibility of glucose ***2 upregulation driven by CD28 signaling reinforced splicing factor recruitment to pre-mRNAs and affected approximately one-third of T-cell activation-induced alternative splicing *** these effects,the CD28-ARS2 axis suppressed the expression of the m1 isoform of pyruvate kinase in favor of PKm2,a key determinant of CD8+T-cell glucose utilization,interferon gamma production,and antitumor effector ***,PKm alternative splicing occurred independently of CD28-driven PI3K pathway activation,revealing a novel means by which costimulation reprograms glucose metabolism in CD8+T cells.

关键词： Immunometabolism mRNA splicing CD8 T cells ARS2 PKm2

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Are there sex-based disparities in cataract surgery?

引用

International Journal of Ophthalmology(English edition) 2024年第1期17卷 137-143页

作者： matthew D.Geiger Anne m.Lynch Alan G.Palestine Nathan C.Grove Karen L.Christopher richard S.Davidson michael J.Taravella Naresh mandava Jennifer L.Patnaik Department of Ophthalmology University of Colorado School of MedicineAuroraCO 80045USA

AIm:To investigate sex-based differences in the occurrence of intra-operative and post-operative complications and associated visual outcomes following cataract ***:This was a retrospective study of patients who had phacoemulsification cataract surgery at the University of Colorado School of *** collected included the patient’s health history,ocular comorbidities,operative and post-operative complications,and the post-operative best corrected visual acuity(BCVA).The data were analyzed using univariate and multivariable logistic regression with generalized estimating equations to account for the correlation of some patients having two eyes included in the ***:A total of 11977 eyes from 7253 patients were included in the *** comorbidities differed by sex,with males having significantly higher percentages of traumatic cataracts(males 0.7%vs females 0.1%),prior ocular surgery(6.7%vs 5.5%),and mature cataracts(2.8%vs 1.9%).Conversely,females had significantly higher rates of pseudoexfoliation(2.0%vs 3.2%).In unadjusted analysis,males had higher rates of posterior capsular rupture(0.8%vs 0.4%)and vitreous loss(1.0%vs 0.6%),but this difference was not significant after adjustment for *** had a significantly increased risk of post-operative retinal detachment,but in multivariable analysis this was no longer *** were significantly less likely to undergo post-operative neodymium-doped yttrium aluminum garnet(Nd:YAG)laser capsulotomy for posterior capsule opacification(OR=0.8,95%CI=0.7-0.9,P=0.0005).The BCVA was slightly worse for males pre-operatively;but post-operatively,both sexes exhibited similar visual acuity of Snellen equivalent 20/***:The study finds that in a cohort of patients presenting for cataract surgery,sex differences exist in pre-operative comorbidities and surgical characteristics that contribute to higher rates of some complications for ***,observed surgical complicatio

关键词： cataract surgery sex-based disparity phacoemulsification outcomes

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Effect of drug therapies on self-reported chemosensory outcomes after COVID-19

引用

World Journal of Otorhinolaryngology-Head and Neck Surgery 2024年第2期10卷 88-96页

作者： marco A.Fornazieri Bruno m.Cunha Samuel P.Nicácio Lucas K.Anzolin JoséL.B.da Silva Aristides Fernandes Neto Deusdedit Brandão Neto richard L.Voegels Fábio D.R.Pinna Department of Surgery Londrina State UniversityLondrinaBrazil Department of medicine Pontifical Catholic University of ParanáLondrinaBrazil Department of Otorhinolaryngology University of São PauloSao PauloBrazil Department of Otorhinolaryngology:Head and Neck Surgery Perelman School of MedicineSmell and Taste CenterUniversity of PennsylvaniaPhiladelphiaPennsylvaniaUSA

Objective:The aim of this study was to assess the relative efficacy of medications used following severe acute respiratory syndrome coronavirus-2(SARS-CoV-2)infection on self-reported alterations in taste and/or smell ***:Seven hundred and fourteen persons with self-reported postcoronavirus disease 2019(post-COVID-19)chemosensory disorders were personally interviewed regarding specific medications they were administered following the acute phase of the *** dependent measure—self-reported total recovery of chemosensory symptoms—was subjected to stepwise logistic *** predictors included demographic and clinical variables,in addition to specific medications used to mitigate disease symptoms(i.e.,systemic corticosteroids,oseltamivir,vitamin C,ibuprofen,hydroxychloroquine,azithromycin,ivermectin,nitazoxanide,anticoagulants,and zinc).Results:The median time between COVID-19 symptom onset and the interviews was 81 days(interquartile range:60-104).Of the 714 subjects,249(34.9%)reported total recovery of their chemosensory function;437(61.2%)had at least one treatment since the beginning of the *** and those with more comorbidities had undergone more *** recovery rates of the treated and nontreated groups did not differ ***,respondents who had used nitazoxanide tended to have a higher rate of self-reported taste or smell *** who took oral zinc were less likely to ***:No medication employed during the first months after SARS-CoV-2 infection had a clear positive effect on returning self-reported smell or taste function to normal,although nitrazoxide trended in a positive *** zinc had a negative effect on the reported recovery of these senses.

关键词： chemosensory disorder coronavirus infections COVID-19 drug therapy SARS-CoV-2 smell loss taste loss

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Call for joint international actions to improve scientific understanding and address soil erosion and riverine sediment issues in mountainous regions

引用

International Soil and Water Conservation Research 2023年第3期11卷 586-588页

作者： Fan Zhang Baoyuan Liu Liping Zhu richard cruse Dongfeng Li Panos Panagos Pasquale Borrelli Yakov Kuzyakov Shaoshan An State Key Laboratory of Tibetan Plateau Earth System Environment and Resources(TPESER)Institute of Tibetan Plateau ResearchChinese Academy of SciencesBeijingChina Beijing Normal University BeijingChina Agronomy Department at Iowa State University AmesIAUnited States Department of Geography National University of SingaporeKent RidgeSingapore European Commission Joint Research CentreIspraItaly Department of Environmental Sciences Environmental GeosciencesUniversity of BaselBaselSwitzerland Department of Science Roma Tre UniversityRomeItaly Department of Soil Science of Temperate Ecosystems Department of Agricultural Soil ScienceGeorg-August-University of GottingenGermany Research Center of Water and Soil Conservation and Ecological Environment Chinese Academy of Sciences&Ministry of EducationYanglingShaanxiChina

During the International Workshop on Soil Erosion and Riverine Sediment in mountainous Regions held in November 2022,scientists from many countries shared their state-of-the-art knowledge and brainstormed to improve scientific understanding for coping with climate change and anthropogenic *** summarized in this discussion includes proposed key scientific questions and suggested joint actions to reduce soil erosion and riverine sediment problems in mountainous regions.

关键词： soil mountainous summarized

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

基于卷积神经网络预测南海海底地形

引用

大地测量与地球动力学 2024年第3期44卷 287-292页

作者：王怀兵万晓云 richard Fiifi Annan 中国地质大学(北京)土地科学技术学院北京市100083

针对南海区域,使用3种重力信号(垂线偏差、重力异常、垂直重力梯度异常)训练卷积神经网络模型,并将预测结果与船测数据和国外模型结果进行对比分析。将3种重力信号分成4组数据:重力异常,重力异常与垂直重力梯度异常,重力异常与垂线偏差... 详细信息

针对南海区域,使用3种重力信号(垂线偏差、重力异常、垂直重力梯度异常)训练卷积神经网络模型,并将预测结果与船测数据和国外模型结果进行对比分析。将3种重力信号分成4组数据:重力异常,重力异常与垂直重力梯度异常,重力异常与垂线偏差,以及重力异常、垂线偏差和垂直重力梯度异常。4种组合方式的反演结果与船测水深之间的标准差分别为104.780 m、102.778 m、93.788 m、88.289 m,表明随着不同类型重力数据的加入,水深预测精度明显提高,并且在深度大于2000 m时,反演结果精度提升效果更为显著。将训练集占总数据集的比例分别设置为80%、70%、60%和50%,反演结果与船测水深之间的标准差分别为88.289 m、91.256 m、92.833 m、96.022 m,表明数据量的增多可以有效提高模型学习结果的精度。

关键词：卷积神经网络重力场信息深度学习海底地形频域法

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Competition between Coral and Algae in Tertiary and Quaternary Reefs: Greenhouse to Icehouse Transitions

引用

Journal of Environmental Protection 2024年第1期15卷 94-107页

作者： Belkasim Khameiss richard Fluegeman William Hoyt Shawn malone Ahmed muftah Kansas Geological Survey Lawrence USA Department of Earth Sciences University of Benghazi Faculty of Science Benghazi Libya Department of Environment Geology and Natural Resources Ball State University Muncie USA Department of Earth and Atmospheric Sciences University of Northern Colorado Greeley USA Department of Geosciences University of Wisconsin—Green Bay Green Bay USA

The competition between coral and algae in marine reefs is pervasive through geologic time;that competition determines the structure and composition of reef communities, which we see in the fossil record. However, the relationships between coral and calcareous algae in reefs are poorly understood. To study this relationship, several hand samples and thin sections were examined from nine different foralgal reef localities around the world. Foralgal reefs typically extend from about 20 m depth or shallower on the seaward side of the reef. The first section is Salt mountain, Alabama, which preserves a Paleocene reef. It contains a high percentage of red coralline algae with benthic foraminifera. The second section is IDOP-U1376, IIA Limestone, it is middle Eocene, in the form of an isolated reef sandwiched between two igneous beds. The third section is the Utoe’ Limestone, New Caledonia, it is middle Eocene in age and is composed mainly of grain-boundstone units with some igneous interlayered. The fourth section is the Darnah Formation in the West-Darnah roadcut section, Northeast Libya, it is middle Eocene in age, it is composed of highly fossiliferous limestone (corals, red coralline algae, echinoids, mollusks, foraminifers, and bryozoans). The fifth section, the Al Bayda Formation (Algal Limestone member) in Northeast Libya, is in the Drayanah—Al Abyar roadcut, Northeast Libya, it has several species of algae but also includes a high percentage of buildups of coral species. The sixth section is the Oligo-miocene Al Faidiyah Formation (Al Fatayah Cement Quarry) limestone unit in Northeast Libya. The seventh section is (Core-core 20) late-early to middle miocene Limestone Unit-Cicuco Field, NW Colombia. The eighth section is the Benghazi Formation at Benghazi Cement Quarry, in Northeast Libya, it is fossiliferous limestone, consisting of coral, algae, mollusks, and echinoids. The ninth and tenth sections are Quaternary reefs in the Bahamas and the Florida Keys, respec

关键词： Utoe’ Limestone New Caledonia Benghazi Formation at Benghazi Cement Quarry Is IDOP-U1376 IIA Limestone It Is middle Eocene

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：