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Environm.ntal tem.eratures,physiology and behavior lim.t the range expansion of invasive Burm.se pythons in southeastern USA

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Integrative Zoology 2012年第3期7卷 271-285页

作者： Elliott R.JACOBSON David G.BARKER Tracy m.BARKER richard m.ULDIN m.chael L.AVERY richard ENGEm.N Stephen SECOR College of Veterinary m.dicine University of FloridaGainesvilleFlorida Vida Preciosa International(VPI) BoerneTexas US Departm.nt of Agriculture Wildlife ServicesNational Wildlife Research CenterFort CollinsColorado US Departm.nt of Agriculture Wildlife ServicesNational Wildlife Research CenterGainesvilleFlorida Departm.nt of Biological Sciences University of AlabamaTuscaloosaAlabamaUSA

A well-established population of Burm.se pythons resides in the Everglades of southern *** in part by a report that identified m.ch of southern USA as suitable habitat for expansion or establishm.nt of the Burm.se python,we exam.ned the plausibility of this snake to survive winters at sites north of the *** integrated daily low and high tem.eratures recorded from.October to February from.2005-2011 at Hom.stead,Orlando and Gainesville,Florida;and Aiken,South Carolina,with m.nim.m.tem.eratures projected for python digestion(16℃),activity(5℃)and survival(0℃).m.an low and high tem.eratures decreased northward from.Hom.stead to Aiken and the num.er of days of freezing tem.eratures increased *** was im.aired or inhibited for 2 m.nths in the Everglades and up to at least 5 m.nths in Aiken,and activity was increasingly lim.ted northward during these *** of overwinter survivorship docum.nt that a single bout of low and freezing tem.eratures results in python *** capacity for Burm.se pythons to successfully overwinter in m.re tem.erate regions of the USA is seem.ngly prohibited because they lack the behaviors to seek refuge from.and the physiology to tolerate,cold *** tropical Southeast Asia is the source of the Everglades Burm.se pythons,we predict it is unlikely that they will be able to successfully expand to or colonize m.re tem.erate areas of Florida and adjoining states due to their lack of behavioral and physiological traits to seek refuge from.cold tem.eratures.

关键词： am.ient tem.erature Burm.se python invasion snake therm.l tolerance

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Inform.tion point and saturation flow at signalized intersections

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Journal of Traffic and Transportation Engineering(English Edition) 2016年第4期3卷 336-344页

作者： Lijun Gao Bhuiyan m. Alam.Brian W. Randolph Douglas K. Nim. richard S. m.rtinko Departm.nt of Civil Engineering University of Toledo Toledo OH 43606 USA Departm.nt of Geography and Planning University of Toledo Toledo OH 43606 USA College of Engineering University of Toledo Toledo OH 43606 USA richard m.rtinko Consulting Maumee OH 43537 USA

This paper introduces an inform.tion point factor and attem.ts to identify how it affects saturation flow and their relationship at signalized intersections. An inform.tion point is defined as any object, structure, or activity located outside of a traveling vehicle that can potentially attract the visual attention of the driver. Saturation flow rates are studied at three pairs of signalized intersections in Toledo, Ohio, USA. Each pair of intersections consists of one intersection with a high num.er of inform.tion points and one intersection with a low num.er of inform.tion points. Study results reveal that, for each pair of intersections, the one with high inform.tion points has a lower saturation flow rate than the one with low inform.tion points. A statistical analysis shows that the differences are significant. Based on the saturation flow data of the paired intersections, inform.tion point effect m.dels are developed and presented in this paper.

关键词： Saturation flowInform.tion pointVisual distractionDriving behaviorTrip generationSignalized intersection

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The role of m.nocytes in optic nerve injury

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Neural Regeneration Research 2023年第8期18卷 1666-1671页

作者： Xiangxiang Liu Yuan Liu m.ham.d m.Khodeiry richard K.Lee Beijing Tongren Eye Center Beijing Tongren HospitalCapital Medical UniversityBeijingChina Bascom.Palm.r Eye Institute Department of OphthalmologyUniversity of Miami Miller School of MedicineMiamiFLUSA

m.nocytes,including m.nocyte-derived m.crophages and resident m.croglia,m.diate m.ny phases of optic nerve injury *** m.croglia respond first,followed by infiltrating m.crophages which regulate neuronal inflam.ation,cell proliferation and differentiation,scar form.tion and tissue rem.deling following optic nerve ***,m.croglia and m.crophages have distinct functions which can be either beneficial or detrim.ntal to the optic nerve depending on the spatial context and tem.oral sequence of their *** divergent effects are attributed to pro-and anti-inflam.atory cytokines expressed by m.nocytes,crosstalk between m.nocyte and glial cells and even m.croglia-m.crophage *** this review,we describe the dynam.cs and functions of m.croglia and m.crophages in neuronal inflam.ation and regeneration following optic nerve injury,and their possible role as therapeutic targets for axonal regeneration.

关键词： fibrotic scar glial scar inflam.ation m.crophage m.croglia optic nerve injury regeneration

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Wildfire severity alters soil m.crobial exoenzym. production and fungal abundances in the southern Appalachian m.untains

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Pedosphere 2024年第5期34卷 865-878页

作者： m.gan L.SCHILL richard BAIRD Shawn P.BROWN Allison m.VEACH Departm.nt of Integrative Biology University of Texas at San AntonioSan Antonio TX 78249USA Biochem.stry Molecular BiologyEntomology and Plant Pathology DepartmentMississippi State UniversityStarkville MS 39762USA Departm.nt of Biological Sciences The University of MemphisMemphis TN 38152USAAntonioand the University of Memphis。

Clim.te change has increased drought frequency and duration that are exacerbated by increased tem.eratures *** effect has,and will continue,to increase fire occurrence across m.ny regions of North *** the southern Appalachian m.untains,wildfires with high burn severity occurred in 2016due to increased drought and hum.n *** investigate the effects of burn severity on soil physicochem.cal properties,m.crobial extracellular enzym. production,and m.crobial abundances in a tem.erate region,surface soils(0-15 cm.were collected from.two sites(the Great Sm.ky m.untains National Park in Tennessee and the Nantahala National Forest in North Carolina,USA)spanning lightly,m.derately,and severely burned areas,accom.anied by adjacent unburned locations that act as *** soil sam.les were collected at three tim. points between 2017 and 2019(i.e.,0.5,1,and 2.5 years post-fire)am.ng burn severity *** hydrolytic enzym. production varied over tim.,with severe burn plots having significantly lower enzym. production at 2.5years *** enzym.s varied am.ng burn severities and across tim. *** burn plots showed greater carbon-specific(β-glucosidase andβ-xylosidase)and phosphorus-specific(acid phosphatase)enzym. activities at 0.5 years post-fire,but this effect was *** 2.5 years post-fire,theβ-xylosidase and acid phosphatase activities were lower in severe or m.derate burn plots relative to the *** contrast,the activity of nitrogen-specific enzym. leucyl am.nopeptidase was the lowest in severe burn plots at 0.5 years post-fire,but was the lowest in light burn plots at 2.5 years *** fungi:bacteria ratio declined with burn severity,indicating that fungi are sensitive or less resilient to high burn severity during *** results suggest that wildfires alter trajectories for soil m.crobial structure and function within a 2.5-year tim.fram.,which potentially has long-term.im.acts on biogeochem.cal

关键词： burn severity extracellular enzym. fungi:bacteria ratio internal transcribed spacer m.crobial structure 16S rRNA

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m.nocyte/m.crophage-m.diated Innate Im.unity in HIV-1 Infection:From.Early Response to Late Dysregulation and Links to Cardiovascular Diseases Onset

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Virologica Sinica 2021年第4期36卷 565-576页

作者： Em.n Teer Danzil E.Joseph richard H.Glashoff m.Faadiel Essop Centre for Cardio-m.tabolic Research in Africa(CARm.) Department of Physiological SciencesStellenbosch UniversityStellenbosch 7600South Africa Division of m.dical m.crobiology&Im.unology Department of PathologyStellenbosch University and NHLSCape Town 7505South Africa

Although m.nocytes and m.crophages are key m.diators of the innate im.une system.the focus has largely been on the role of the adaptive im.une system.in the context of hum.n im.unodeficiency virus(HIV)*** m.re attention and research work regarding the innate im.une system.especially the role of m.nocytes and m.crophages during early HIV-1 infection-is *** m.nocytes and tissue m.crophages are both susceptible targets of HIV-1 infection,and the early host response can determ.ne whether the nature of the infection becom.s pathogenic or *** exam.le,m.nocytes and m.crophages can contribute to the HIV reservoir and viral persistence,and influence the initiation/extension of im.une activation and chronic *** the expansion of m.nocyte subsets(classical,interm.diate and non-classical)provide an increased understanding of the crucial role they play in term. of chronic inflam.ation and also by increasing the risk of coagulation during HIV-1 *** review discusses the role of m.nocytes and m.crophages during HIV-1 pathogenesis,starting from.the early response to late dysregulation that occurs as a result of persistent im.une activation and chronic *** changes are also linked to downstream.targets such as increased coagulation and the onset of cardiovascular diseases.

关键词： m.nocytes Hum.n im.unodeficiency virus(HIV) Persistent im.une activation Coagulation Cardiovascular diseases(CVD)

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Neuropsychological Assessm.nt of Learning and m.m.ry in Rats Following Ketam.ne Exposure during Late Adolescence

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Journal of Behavioral and Brain Science 2020年第12期10卷 568-589页

作者： Julianna m. davis David Com.ton m.randa Heit Ashley Fravel Kim.erly Wood Departm.nt of Psychology Behavioral Neuroscience Program Palm Beach Atlantic University West Palm Beach USA

With the prevalent issue of drug abuse in society, research regarding the effects of ketam.ne, a drug frequently abused by youth in club settings, has increased. Despite its potential for m.suse, ketam.ne has dem.nstrated potential as a fast-acting antidepressant and seem. to work well for relieving treatm.nt-resistant depression. However, previous research has shown ketam.ne use m.y cause im.airm.nts in frontal and m.dial tem.oral lobe functioning, leading to problem. with m.m.ry. While under the influence of ketam.ne, individuals also display problem. with spatial working m.m.ry when com.ared to individuals not dosed with ketam.ne. The m.jority of previous research has exam.ned the short-term.im.act of ketam.ne use with studies on neurodevelopm.nt largely confined to postnatal exposure. In the present study, the long-term.effects on m.m.ry caused by repeated ketam.ne exposure during late adolescence were exam.ned. Rats were used as nonhum.n m.dels in order to investigate the cognitive risks resulting from.chronic use of ketam.ne. The results indicated that low-ketam.ne dosed rats dem.nstrated significantly better spatial m.m.ry recall com.ared to high-ketam.ne dosed rats. In addition, high-ketam.ne dosed rats appeared to struggle m.re with working m.m.ry than the rats in the low-ketam.ne and control groups. Sim.larly, both drug groups showed significantly m.re working m.m.ry and reference m.m.ry errors than the control group. This indicates that higher doses of ketam.ne during late adolescence m.y cause working and spatial m.m.ry im.airm.nts later in life.

关键词： Ketam.ne m.m.ry Im.airm.nts Long-Term.Effects Spatial m.m.ry Working m.m.ry

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二阶时滞微分方程边值问题的上下解方法

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数学学报（中文版） 2010年第3期53卷 489-494页

作者：王宏洲 richard m. TIm.NEY 北京理工大学数学系北京100081 School of m.them.tics Trinity College DublinDublinIreland

主要利用上下解方法和Schauder不动点定理,研究一类二阶时滞微分方程边值问题的正解存在性.为了验证结论的正确性,本文在结尾部分给出了两个例子.

关键词：边值问题时滞上下解

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Therapeutic potential of alpha 5 subunit containing GABA_(A) receptors in Alzheim.r's disease

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Neural Regeneration Research 2021年第8期16卷 1550-1551页

作者： Andrea Kwakowsky Henry J.Waldvogel richard L.m.Faull Centre for Brain Research Department of Anatomy and Medical ImagingFaculty of Medical and Health SciencesUniversity of AucklandAucklandNew Zealand

Alheim.r's disease(AD) is a com.on neurodegenerative disorder and the leading cause of dem.ntia. It has been estim.ted that over 50 m.llion people worldwide were affected by dem.ntia in 2019, and the prevalence of dem.ntia is expected to double approxim.tely once every 20 years(Govindpani et al., 2017). m.st people who die with AD require high levels of care for long periods of tim..

关键词： al. Alzheim.r Therapeutic

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Crowth Arrest Recovery Lines in Hypoparathyroidism.1

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实用放射学杂志 1987年第3期 166-167页

作者： richard A. Rosen, m. D Sheila m. Deshm.kh, m. D.

BECAUSE of the infrequency of hypoparathyroidism.and the Paucity of radiographic findings observed in this disease, the diagnosis is rarely m.de by the radiologist. By far the m.st com.on cause of the process is the i... 详细信息

关键词： Crowth Arrest Recovery Lines in Hypoparathyroidism.1

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Infrared chem.cal im.ging through non-degenerate two-photon absorption in silicon-based cam.ras

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Light(Science & Applications) 2020年第1期9卷 813-822页

作者： David Knez Adam.m.Hanninen richard C.Prince Eric O.Potm. Dm.try A.Fishm.n Departm.nt of Chem.stry University of CaliforniaIrvineCA 92697USA Departm.nt of Biom.dical Engineering University of CaliforniaIrvineCA 92697USA

Chem.cal im.ging based on m.d-infrared(m.R)spectroscopic contrast is an im.ortant technique with a m.riad of applications,including biom.dical im.ging and environm.ntal *** m.R cam.ras,however,lack perform.nce and are m.ch less affordable than m.ture Si-based devices,which operate in the visible and nearinfrared ***,we dem.nstrate fast m.R chem.cal im.ging through non-degenerate two-photon absorption(NTA)in a standard Si-based charge-coupled device(CCD).We show that wide-field m.R im.ges can be obtained at 100 m. exposure tim.s using picosecond pulse energies of only a few fem.ojoules per pixel through NTA directly on the CCD *** this on-chip approach does not rely on phase m.tching,it is alignm.nt-free and does not necessitate com.lex postprocessing of the *** em.hasize the utility of this technique through chem.cally selective m.R im.ging of polym.rs and biological sam.les,including m.R videos of m.ving targets,physical processes and live nem.todes.

关键词： absorption Infrared chem.cal

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