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A critical review of the fatigue life prediction of asphalt mixtures and pavements

Journal of Traffic and Transportation Engineering(English Edition) 2022年第5期9卷 808-835页

作者： Nithin Sudarsanan Youngsoo richard kim Department of Civil Constructionand Environmental EngineeringNorth Carolina State UniversityRaleighNC 27695USA

New pavement construction techniques and the increased use of recycled materials have led to unexpected and premature pavement failure in recent *** pavement’s exposure to daily and seasonal extreme temperature and repeated vehicular loads accumulate *** cracking occurs once the cumulative damage surpasses the material’s cracking *** crack is the most common pavement cracking *** the past four decades,researchers have carried out numerous experiments and analyses to understand pavement *** paper aims to provide an overview of fatigue cracking and discuss various fatigue test methods for characterizing asphalt concrete *** article also discusses the most common phenomenological and mechanistic models for predicting the fatigue life of asphalt concrete pavements based on different fatigue test *** paper details the implementation of the commonly used numerical models found in numerical simulation software and their prediction ability for the fatigue life of a pavement *** major flaws in current evaluation methods are the sensitivity of experimental results and the lack of reliability of some predictive *** asphalt material characterization is the ongoing practice for determining the most appropriate performance evaluation ***,proceeding with future research objectives is unrealistic until the accuracy of the tests and reliability of the predictions can be verified against actual field *** critical review of the fatigue life predictions of asphalt mixtures and pavements should help to refine or redefine the right course of action for future research.

关键词： Fatigue cracking Failure criteria Fracture mechanics Simplified viscoelastic continuum damage(S-VECD)model Mechanistic-Empirical Pavement Design Guideline(MEPDG)

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Effect of synthetic fibers on the mechanical performance of asphalt mixture:A review

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Journal of Traffic and Transportation Engineering(English Edition) 2023年第3期10卷 331-348页

作者： Haichuan Jia Yanping Sheng Ping Guo Shane Underwood Huaxin Chen Y.richard kim Yan Li Qingwei Ma School of Materials Science and Engineering Chang'an UniversityXi'an 710064China Department of Civil Constructionand Environmental EngineeringNorth Carolina State UniversityRaleighNC 27695USA Engineering Research Center of Transportation Materials of Ministry of Education School of Materials Science and EngineeringChang'an UniversityXi'an 710064China Xi'an Highway Research Institute Co. Ltd.Xi'an 710065China

Numerous studies showed that synthetic fibers are effective for reinforcing the mechanical performance of the asphalt mixture due to their high strength properties,ductility,and durability *** this paper,the objective is to present a review of the reinforcement effect of synthetic fiber on the mechanical performance of the asphalt *** paper reviews the relevant literature on the characterizations and applications of synthetic fibers to improve different mechanical properties of asphalt mixes,which can provide a reference for the applications and development of synthetic fibers in asphalt *** characteristics of common synthetic fibers are introduced and the utilization of synthetic fibers in asphalt mixture is *** surface treatment methods for fiber are reviewed and it is found that surface treatment can improve the performance of the synthetic fibers in asphalt mixtures,especially the chemical surface treatment *** influence of synthetic fiber addition on the mechanical properties of the asphalt concrete such as rutting resistance,tensile strength,water stability performance,and cracking resistance are then *** research results show that aramid,glass,and polyester fibers improve the fatigue cracking resistance of asphalt *** fibers,polyamide fibers,and carbon fibers are used to improve resistance to the permanent deformation of asphalt pavement.

关键词： Fiber reinforced asphalt mixture Synthetic fibers Fiber characteristics Mechanical performance

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Prolonged penile strangulation with metal clamps

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Asian Journal of Andrology 2006年第1期8卷 105-106页

作者： Chirag Patel richard kim Michael Delterzo Section of Urology University of Texas Health Science Center at HoustonHoustonTexas 77030USA

Various different objects have been reported to strangulate the penis,We reported on a patient who used metal radiator clamps for an extended period of time .Workup included history,physical examination and *** patient was taken to the operating room for further evaluation with cystourethroscopy and orthopedic wire cutters were used to break the metal bands.（Asian J Androl 2006Jan;8：105-106）

关键词： penis penile strangulation metal clamps

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Construction quality acceptance performance-related specifications for chip seals

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Journal of Traffic and Transportation Engineering(English Edition) 2019年第4期6卷 337-348页

作者： Javon Adams Cassie Castorena Y.richard kim Department of Civil Construction and Environmental Engineering North Carolina State University

The research described herein details the establishment of a framework for construction quality acceptance performance-related specifications(PRS) for chip seal surface treatments. This paper establishes acceptance quality characteristics(AQCs) and relationships between the AQCs and related chip seal performance measures. This work is a critical step in developing PRS for constructed chip seal treatments and establishing suitable guidelines for the PRS. The main objective of this paper is to determine appropriate test methods to evaluate each defined AQC. The relationships that are established between the AQCs and chip seal performance are used to define performance ranges and threshold values for a particular performance measure. These performance ranges and threshold values then can be used to define pay factors for the constructed chip seal section. The threshold values and pay factors for each AQC described herein are preliminary recommendations and require further validation prior to implementation. However, this research demonstrates how these PRS would be utilized to ensure acceptable chip seal construction quality in the *** developed construction quality acceptance PRS framework uses the percent within limits(PWL) concept to determine whether a chip seal lot passes the PRS threshold values and whether the contractor receives full pay, is subject to a pay penalty, or fails the construction PRS and must correct the chip seal within the first year in service, which constitutes the typical warranty period for contracted chip seal ***, recommendations are made as to the next steps in the development and validation of these construction quality acceptance PRS that are needed for implementation by contractors and state roadway maintenance agencies.

关键词： Performance-related specifications(PRS) Chip seal Construction Quality assurance Percent within limits

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Biofabrication of nanocomposite-based scaffolds containing human bone extracellularmatrix for the differentiation of skeletal stem and progenitor cells

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Bio-Design and Manufacturing 2024年第2期7卷 121-136页

作者： Yang-Hee kim Janos M.Kanczler Stuart Lanham Andrew Rawlings Marta Roldo Gianluca Tozzi Jonathan I.Dawson Gianluca Cidonio richard O.C.Oreffo Faculty of Medicine Bone and Joint Research GroupCentre for Human DevelopmentStem Cells and RegenerationInstitute of Developmental SciencesUniversity of SouthamptonSouthampton SO166YDUK School of Pharmacy and Biomedical Science University of PortsmouthPortsmouth PO12DTUK School of Engineering Faculty of Engineering and ScienceUniversity of GreenwichGreenwich ME44TBUK Center for Life Nano-and Neuro-Science(CLN2S) Italian Institute of Technology00161 RomeItaly

Autograft or metal implants are routinely used in skeletal ***,they fail to provide long-term clinical resolution,necessitating a functional biomimetic tissue engineering *** use of native human bone tissue for synthesizing a biomimeticmaterial inkfor three-dimensional(3D)bioprintingof skeletal tissueis anattractivestrategyfor ***,human bone extracellular matrix(bone-ECM)offers an exciting potential for the development of an appropriate microenvironment for human bone marrow stromal cells(HBMSCs)to proliferate and differentiate along the osteogenic *** this study,we engineered a novel material ink(LAB)by blending human bone-ECM(B)with nanoclay(L,Laponite®)and alginate(A)polymers using extrusion-based *** inclusion of the nanoﬁller and polymeric material increased the rheology,printability,and drug retention properties and,critically,the preservation of HBMSCs viability upon *** composite of human bone-ECM-based 3D constructs containing vascular endothelial growth factor(VEGF)enhanced vascularization after implantation in an ex vivo chick chorioallantoic membrane(CAM)*** inclusion of bone morphogenetic protein-2(BMP-2)with the HBMSCs further enhanced vascularization and mineralization after only seven *** study demonstrates the synergistic combination of nanoclay with biomimetic materials(alginate and bone-ECM)to support the formation of osteogenic tissue both in vitro and ex vivo and offers a promising novel 3D bioprinting approach to personalized skeletal tissue repair.

关键词： Extracellular matrix Nanoclay Bone 3D bioprinting

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Application of viscoelastic continuum damage approach to predict fatigue performance of Binzhou perpetual pavements

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Journal of Traffic and Transportation Engineering(English Edition) 2016年第2期3卷 104-115页

作者： Wei Cao Amirhossein Norouzi Y.richard kim Department of Civil and Environmental Engineering Louisiana State UniversityBaton RougeLA 70803USA Department of Civil Constructionand Environmental EngineeringNorth Carolina State UniversityRaleighNC27695USA

For this study, the Binzhou perpetual pavement test sections constructed in Shandong Province, China, were simulated for long-term fatigue performance using the layered viscoelastic pavement analysis for critical distresses （LVECD） finite element software package. In this framework, asphalt concrete was treated in the context of linear visco- elastic continuum damage theory. A recently developed unified fatigue failure criterion that defined the boundaries of the applicable region of the theory was also incorporated. The mechanistic modeling of the fatigue mechanisms was able to accommodate the complex temperature variations and loading conditions of the field pavements in a rigorous manner. All of the material models were conveniently characterized by dynamic modulus tests and direct tension cyclic fatigue tests in the laboratory using cylindrical specimens. By comparing the obtained damage characteristic curves and failure criteria, it is found that mixtures with small aggregate particle sizes, a dense gradation, and modified asphalt binder tended to exhibit the best fatigue resistance at the material level. The 15 year finite element structural simulation results for all the test sections indicate that fa- tigue performance has a strong dependence on the thickness of the asphalt pavements. Based on the predicted location and severity of the fatigue damage, it is recommended that Sections 1 and 3 of the Binzhou test sections be emoloved for perpetual pavement design.

关键词： Perpetual pavement Fatigue cracking Continuum damage theory Failure criterion LVECD

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Prognostic value of pre-treatment F-18-FDG PET-CT in patients with hepatocellular carcinoma undergoing radioembolization

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World Journal of Gastroenterology 2016年第47期22卷 10406-10414页

作者： Yazan Abuodeh Arash O Naghavi Kamran A Ahmed Puja S Venkat Youngchul kim Bela Kis Junsung Choi Benjamin Biebel Jennifer Sweeney Daniel A Anaya richard kim Mokenge Malafa Jessica M Frakes Sarah E Hoffe Ghassan El-Haddad Department of Radiation Oncology H Lee Moffitt Cancer Center and Research Institute Department of Interventional Radiology H Lee Moffitt Cancer Center and Research Institute Department of Gastrointestinal Oncology H Lee Moffitt Cancer Center and Research Institute

AIM To evaluate the value of pre-treatment 18F-FDG PET/CT in patients with HCC following liver *** We identified 34 patients with HCC who underwent an FDG PET/CT scan prior to hepatic radioembolization at our institution between 2009 and 2013. Patients wereseen in clinic one month after radioembolization and then at 2-3 mo intervals. We assessed the influence of FDG tumor uptake on outcomes including local liver control(LLC), distant liver control(DLC), time to distant metastases(DM), progression free survival(PFS) and overall survival(OS).RESULTS The majority of patients were males(n = 25, 74%), and had Child Pugh Class A(n = 31, 91%), with a median age of 68 years(46-84 years). FDG-avid disease was found in 19(56%) patients with SUVmax ranging from 3 to 20. Female patients were more likely to have an FDG-avid HCC(P = 0.02). Median follow up of patients following radioembolization was 12 months(1.2-62.8 mo). FDG-avid disease was associated with a decreased 1 year LLC, DLC, DM and PFS(P < 0.05). Using multivariate analysis, FDG avidity predicted for LLC, DLC, and PFS(all P < 0.05).CONCLUSION In this retrospective study, pre-treatment HCC FDGavidity was found to be associated with worse LLC, DLC, and PFS following radioembolization. Larger studies are needed to validate our initial findings to assess the role of F-18-FDG PET/CT scans as biomarker for patients with HCC following radioembolization.

关键词： F-18 fluorodeoxyglucose 宠物 Hepatocellular 癌 Radioembolization 预后 Biomarker

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Neo-adjuvant therapy for hepatocellular carcinoma before liver transplantation:Where do we stand?

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World Journal of Gastroenterology 2014年第18期20卷 5308-5319页

作者： Masato Fujiki Federico Aucejo Minsig Choi richard kim Transplant Center Cleveland ClinicClevelandOH 44195United States Department of Gastrointestinal Oncology Wayne State University/Karmonos Cancer Center DetroitMI 48202United States Department of Gastrointestinal Oncology H Lee Moffitt Cancer CenterTampaFL 33612United States

Liver transplantation(LT)for hepatocellular carcinoma(HCC)within Milan criteria is a widely accepted optimal ***-adjuvant therapy before transplantation has been used as a bridging therapy to prevent dropout during the waiting period and as a down-staging method for the patient with intermediate HCC to qualify for liver *** chemoembolization and radiofrequency ablation are the most commonly used method for locoregional *** data associated with newer modalities including drugeluting beads,radioembolization with Y90,stereotactic radiation therapy and sorafenib will be discussed as a tool for converting advanced HCC to LT *** concept"ablate and wait"has gained the popularity where mandated observation period after neoadjuvant therapy allows for tumor biology to become apparent,thus has been recommended after *** role of neo-adjuvant therapy with conjunction of"ablate and wait"in living donor liver transplantation for intermediate stage HCC is also discussed in the paper.

关键词： Bridging therapy Neo-adjuvant therapy Locoregional

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Management of borderline resectable pancreatic cancer

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World Journal of Gastrointestinal Oncology 2015年第10期7卷 241-249页

作者： Amit Mahipal Jessica Frakes Sarah Hoffe richard kim Department of Gastrointestinal Oncology H. Lee Moffitt Cancer Center and Research Institute Department of Radiation Oncology H. Lee Moffitt Cancer Center and Research Institute

Pancreatic cancer is the fourth most common cause of cancer death in the United States. Surgery remains the only curative option; however only 20% of the patients have resectable disease at the time of initialpresentation. The definition of borderline resectable pancreatic cancer is not uniform but generally denotes to regional vessel involvement that makes it unlikely to have negative surgical margins. The accurate staging of pancreatic cancer requires triple phase computed tomography or magnetic resonance imaging of the pancreas. Management of patients with borderline resectable pancreatic cancer remains unclear. The data for treatment of these patients is primarily derived from retrospective single institution experience. The prospective trials have been plagued by small numbers and poor accrual. Neoadjuvant therapy is recommended and typically consists of chemotherapy and radiation therapy. The chemotherapeutic regimens continue to evolve along with type and dose of radiation therapy. Gemcitabine or 5-fluorouracil based chemotherapeutic combinations are administered. The type and dose of radiation vary among different institutions. With neoadjuvant treatment, approximately 50% of the patients are able to undergo surgical resections with negative margins obtained in greater than 80% of the patients. Newer trials are attempting to standardize the definition of borderline resectable pancreatic cancer and treatment regimens. In this review, we outline the definition, imaging requirements and management of patients with borderline resectable pancreatic cancer.

关键词： Pancreatic cancer Surgery Chemotherapy Radiation B

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Fatigue Performance Modeling of Binzhou Perpetual Pavements Using Viscoelastic Continuum Damage Finite Element Program

Fatigue Performance Modeling of Binzhou Perpetual Pavements ...

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ISAP2012重载沥青路面和桥面铺装专题会议

作者： Wei Cao Mehran Eslaminia Youngsoo richard kim North Carolina State University

＜正＞This paper presents a study that uses an in-house developed,Fourier-transform based finite element analysis program,FFE,to compute the pavement response under moving traffic loads and then to predict the long-term fatigue performance of the *** the analysis,the asphalt mixtures are considered as linear viscoelastic（LVE） materials and the unbound layers as linear elastic *** traffic is modeled by certain passes of a wheel load that are distributed in a haversine pattern on a circular contact *** the response data are obtained,they serve as the

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