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Finite Capacitive Response at the Quantum Hall Plateau

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Chinese Physics letters 2022年第9期39卷 53-56页

作者：赵利利林文璐 Y.J.Chung K.W.Baldwin l.N.Pfeiffer 刘阳 International Center for Quantum Materials Peking UniversityBeijing 100871China Department of Electrical Engineering Princeton UniversityPrincetonNew Jersey 08544USA

We study ultra-high-mobility two-dimensional(2D)electron/hole systems with high precision capacitance *** is found that the capacitance charge appears only at the fringe of the gate at high magnetic field when the 2D conductivity decreases *** integer quantum Hall effects,the capacitance vanishes and forms a plateau at high temperatures T≥300 m K,which surprisingly disappears at T≤100 m *** anomalous behavior is likely a manifestation that dilute particles/vacancies in the top-most landau level form Wigner crystals,which have finite compressibility and can host polarization current.

关键词： capacitance integer dilute

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倾斜转弯导弹的次优制导规律

上海航天 1989年第1期6卷 16-23页

作者： Romesh K.Aggarwal Charles R.moore 陈渊

倾斜转弯(BTT)导弹的非线性的俯仰和偏航动态耦合,是由导弹的侧向加速度和倾斜角引起的。由于这些非线性动态特性,最优加速度和倾斜速率指令的解只能通过两点边值问题求解的数值方法得到。具体实现时,必须有相应于现行系统状态其它部分... 详细信息

倾斜转弯(BTT)导弹的非线性的俯仰和偏航动态耦合,是由导弹的侧向加速度和倾斜角引起的。由于这些非线性动态特性,最优加速度和倾斜速率指令的解只能通过两点边值问题求解的数值方法得到。具体实现时,必须有相应于现行系统状态其它部分的动态过程,最优控制问题的解可以用扰动技术得到,这种技术根据能解的降阶问题的解,然后规定降阶解组合成全阶问题的近似解的方法,把系统分成慢速和快速状态。这种技术过去已被用于飞机和导弹弹道最优问题,可是这个问题的表述与其他问题不同。因为小扰动系数是滚动控制代价的加权因子。这样当这参数较小时,滚动控制代价也变得非常小,即这问题看成是"经济控制"问题。合成解由作为现行系统状态函数的滚动速率和加速度指令组合,"零阶慢速"解是侧滑转弯导弹的最优制导律。认为滚动速率无限快,忽略导弹倾斜角的动态情况可有效地获得这个解。"零阶快速"解提供滚动指令,这被认为是补偿倾斜角有限动态特性的校正项。慢速解需要一个"一阶"校正项,通常这一项用扰动理论来获得。但是对于这个问题,一个恰当"慢速"解能通过最优条件来得到,在仿真比较中,利用反向扫描方法可获得最优解,结果表明,BTT 导弹的"次优制导规律"是有效的。

关键词：导弹制导次优制导规律倾斜转弯

Sonicating bees demonstrate flexible pollen extraction without instrumental learning

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Current Zoology 2019年第4期65卷 425-436页

作者： Callin M. Switzer Avery l. Russell Daniel R. Papaj Stacey A. Combes Robin Hopkins Department of Organismic and Evolutionary Biology Harvard University Cambridge MA USA Arnold Arboretum Harvard University Boston MA USA Department of Ecology and Evolutionary Biology University of Arizona Tucson AZ USA Department of Neurobiology Physiology and Behavior University of California at Davis Davis CA USA Department of Biology and eScience Institute University of Washington Seattle WA USA Department of Biological Sciences University of Pittsburgh Pittsburgh PA USA

Pollen collection is necessary for bee survival and important for flowering plant reproduction, yet if and how pollen extraction motor routines are modified with experience is largely unknown. Here, we used an automated reward and monitoring system to evaluate modification in a common pollen-extraction routine, floral sonication. Through a series of laboratory experiments with the bumblebee, Bombus impatiens, we examined whether variation in sonication frequency and acceleration is due to instrumental learning based on rewards, a fixed behavioral response to rewards, and/or a mechanical constraint. We first investigated whether bees could learn to adjust their sonication frequency in response to pollen rewards given only for specified frequency ranges and found no evidenee of instrumental learning. However, we found that absenee versus receipt of a pollen reward did lead to a predictable behavioral resp on se, which depe nded on bee size. Fin ally, we found some evide nee of mechanical con straints, in that flower mass affected sonication acceleration (but not frequency) through an interaction with bee size. In generalz larger bees showed more flexibility in sonication frequency and acceleration, potentially reflecting a size-based constraint on the range over which smaller bees can modify frequency and accelerati on. Overall our results show that although bees did not display instrumental learning of sonication frequency, their sonication motor routine is nevertheless flexible.

关键词： Bombus impatiens buzz pollination foraging innate behavior learned behavior Solanum

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肿瘤蛋白免疫测定新方法

国际检验医学杂志 1989年第1期25卷 27-29页

作者： moore JP et al 于泉张丽娟

前癌基因ras(N-ras,ki-ras,Ha-ras)和myc(C-myc,N-myc,l-myc)家族是调节细胞生长的重要组分。ras 蛋白与GTP 结合在生物化学信号转导中起作用,这些生化信号可以通过生长因子受体激活静止期细胞。增加C-myc 表达可使细胞对这些信号作出... 详细信息

前癌基因ras(N-ras,ki-ras,Ha-ras)和myc(C-myc,N-myc,l-myc)家族是调节细胞生长的重要组分。ras 蛋白与GTP 结合在生物化学信号转导中起作用,这些生化信号可以通过生长因子受体激活静止期细胞。增加C-myc 表达可使细胞对这些信号作出快速应答反应。所有的myc 蛋白均位于细胞核内,虽然已经有人提出有关C-myc 的作用。

关键词：免疫测定肿瘤蛋白静止期细胞细胞生长信号转导生长因子受体癌基因微孔板成纤维细胞基因表达

Increased survivin expression contributes to apoptosis-resistance in IPF fibroblasts

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Advances in Bioscience and Biotechnology 2012年第6期3卷 657-664页

作者： Thomas H. Sisson Toby M. Maher Iyabode O. Ajayi Jessie E. King Peter D.R. Higgins Adam J. Booth Rommel l. Sagana Steven K. Huang Eric S. White Bethany B. moore Jeffrey C. Horowitz Division of Gastroenterology Department of Medicine University of Michigan Medical Center 1150 W. Medical Center Dr. Ann Arbor MI 48109 Division of Pulmonary and Critical Care Medicine Department of Medicine University of Michigan Medical Center 1150 W. Medical Center Dr. Ann Arbor MI 48109 Interstitial lung Disease Unit Royal Brompton Hospital London

Fibroblasts perform critical functions during the normal host response to tissue injury, but the inappropriate accumulation and persistent activation of these cells results in the development of tissue fibrosis. The mechanisms accounting for the aberrant accumulation of fibroblasts during fibrotic repair are poorly understood, although evidence supports a role for fibroblast resistance to apoptosis as a contributing factor. We have shown that TGF-β1 and endothelin-1 (ET-1), soluble mediators implicated in fibrogenesis, promote fibroblast resistance to apoptosis. Moreover, we recently found that ET-1 induced apoptosis resistance in normal lung fibroblasts through the upregulation of survivin, a member of the Inhibitor of Apoptosis (IAP) protein family. In the current study, we sought to determine the role of survivin in the apoptosis resistance of primary fibroblasts isolated from the lungs of patients with Idiopathic Pulmonary Fibrosis (IPF), a fibrotic lung disease of unclear etiology for which there is no definitive therapy. First, we examined survivin expression in lung tissue from patients with IPF and found that there is robust expression in the fibroblasts residing within fibroblastic foci (the “active” lesions in IPF which correlate with mortality). Next, we show that survivin expression is increased in fibroblasts isolated from IPF lung tissue compared to cells from normal lung tissue. Consistent with a role in fibrogenesis, we demonstrate that TGF-β1 increases survivin expression in normal lung fibroblasts. Finally, we show that inhibition of survivin enhances susceptibility of a subset of IPF fibroblasts to apoptosis. Collectively, these findings suggest that increased survivin expression represents one mechanism contributing an apoptosis-resistant phenotype in IPF fibroblasts.

关键词： Myofibroblast Idiopathic Pulmonary Fibrosis Inhibitor of Apoptosis lung Fibrosis Fas

榅桲总黄酮对自发性高血压大鼠血压和血管内皮功能的影响

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中华中医药杂志 2017年第3期32卷 1287-1290页

作者：周文婷古再努尔.买买提阿迪力.阿不都热合曼邬利娅.伊明 moore Nicholas 艾尼瓦尔.吾买尔新疆医科大学基础医学院药理教研室乌鲁木齐830011 法国波尔多大学药理教研室法国波尔多33076

目的:研究榅桲总黄酮对自发性高血压大鼠血压和血管内皮功能的影响。方法:自发性高血压大鼠分为模型组,卡托普利组(25mg·kg^(-1)·d^(-1)),杜仲平压片组(30mg·kg^(-1)·d^(-1)),榅桲总黄酮低、中、高剂量组(40、80、160mg·kg^(-1)·d... 详细信息

目的:研究榅桲总黄酮对自发性高血压大鼠血压和血管内皮功能的影响。方法:自发性高血压大鼠分为模型组,卡托普利组(25mg·kg^(-1)·d^(-1)),杜仲平压片组(30mg·kg^(-1)·d^(-1)),榅桲总黄酮低、中、高剂量组(40、80、160mg·kg^(-1)·d^(-1)),WKY大鼠作正常对照。灌胃给药16周,每2周测定血压1次,末次给药后分别测定血清内皮素-1(ET-1)、一氧化氮(NO)、内皮型一氧化氮合酶(e NOS)、超氧化物歧化酶(SOD)、丙二醛(MDA)及降钙素基因相关肽(CGRP)的含量,评价榅桲总黄酮对自发性高血压大鼠血压和血管内皮功能的影响。结果:与模型组比较,榅桲总黄酮各剂量组大鼠收缩压和舒张压均呈降低趋势,ET-1和MDA水平降低而NO、e NOS、SOD及CGRP水平均有不同程度升高(P<0.01,P<0.05)。结论:榅桲总黄酮可降低自发性高血压大鼠血压,作用机制可能与抑制血管内皮功能障碍,调节血管舒缩因子释放有关。

关键词：榅桲总黄酮自发性高血压大鼠血管内皮

Indicators of success for smart law enforcement in protected areas:A case study for Russian Amur tiger(Panthera tigris altaica)reserves

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Integrative Zoology 2016年第1期11卷 2-15页

作者： Michiel H.H.HÖTTE Igor A.KOlODIN Sergei l.BEREZNUK Jonathan C.SlAGHT linda l.KERlEY Svetlana V.SOUTYRINA Galina P.SAlKINA Olga Y.ZAUMYSlOVA Emma J.STOKES Dale G.MIQUEllE Wildlife Conservation Society BronxNew YorkUSA Phoenix Fund VladivostokRussian Federation Zoological Society of london Regent’s ParkLondonEngland Sikhote-Alin Biosphere Zapovednik Primorskii KraiRussian Federation lazovskii State Nature Zapovednik Primorskii KraiRussian Federation Department of Ecology Far Eastern Federal UniversityAyaksRusski Island

Although considerable conservation resources have been committed to develop and use law enforcement monitoring and management tools such as SMART,measures of success are ill-defined and,to date,few reports detail results ***,we present 4 case studies from protected areas with Amur tigers(Panthera tigris altaica)in Russia,in which indicators of success were defined and evaluated at *** ultimate goal was an increase in tiger numbers to 1 individual/100 km^(2)at each *** predicted that improvements in law enforcement effectiveness would be followed by increases in prey numbers and,subsequently,tiger *** used short-term and long-term indicators of success,including:(i)patrol team effort and effectiveness;(ii)catch per unit effort indicators(to measure reductions in threats);and(iii)changes in target species *** addition to implementing a monitoring system,we focused on improving law enforcement management using an adaptive management *** 4 years,we noted clear increases in patrol effort and a partial reduction in *** we did not detect clear trends in ungulate numbers,tiger populations remained stable or increased,suggesting that poaching of tigers may be more limiting than prey *** effectiveness is needed before a clear reduction in threats can be noted,and more time is needed before detecting responses in target ***,delineation of concrete goals and indicators of success provide a means of evaluating progress and *** monitoring should be a central component of law enforcement strategies for protected areas.

关键词： adaptive patrol management Amur tiger anti-poaching law enforcement monitoring SMART

2003年10月至2004年2月与马里兰州大洋城一家旅馆饮用水相关的军团菌病

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美国医学会杂志（中文版） 2006年第5期25卷 319-320页

作者： D Goeller D Blythe M Davenport M Blackburn B Flannery C lucas B Fields M moore AD Castel l Hicks 肖燕（译）崔德健（校） Worcester County Health Dept Snow Hill Maryland Dept of Health and Mental Hygiene Div of Bacterial and Mycotic Diseases National Center for Infectious Diseases EIS officers CDC. 不详

2003年10月至2004年2月，在马里兰州大洋城一家旅馆住过的旅客中诊断出8例军团菌病（7例确诊，1例疑似）。本报告对伍斯特县卫生局（WCHD）、马里兰州健康及心理卫生署（DHMH）和疾病预防与控制中心（CDC）随后进行的一项联合调查进行... 详细信息

2003年10月至2004年2月，在马里兰州大洋城一家旅馆住过的旅客中诊断出8例军团菌病（7例确诊，1例疑似）。本报告对伍斯特县卫生局（WCHD）、马里兰州健康及心理卫生署（DHMH）和疾病预防与控制中心（CDC）随后进行的一项联合调查进行了总结。调查指出，该旅馆的饮用热水系统极有可能是传染源。这次爆发强调了加强以州为基础的监控对及时诊断和控制旅游相关军团菌病的重要性。

关键词：军团菌病旅馆兰州马里饮用疾病预防与控制中心水相县卫生局

HFO as the main contaminant carrier and transporting agent downstream the Zarshuran As deposit, NW Iran

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Chinese Journal Of Geochemistry 2006年第B8期25卷 46-46页

作者： Soroush Modabberi Farid moore Water ＆ Soil Pollution Investigation Bureau Department of Environment Tehran Iran Department of Earth Science Shiraz University Shiraz Iran