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Toward the implementation of a universal angle-based optical indoor positioning system

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Frontiers of Optoelectronics 2018年第2期11卷 116-127页

作者： Mark H. BeRGeN Ferdinand S. SCHAAL richard KLUKAS Julian CHeNG Jonathan e HOLZMAN Faculty of Applied Science University of British Columbia Kelowna BC V1V 1V7 Canada Technical University of Denmark Anker Engelunds Vej 1 Bygning 101A 2800 Kgs. Lyngby Denmark

There is an emerging market today for indoor positioning systems capable of working alongside global navigation satellite systems, such as the global positioning system, in indoor environments. Many systems have been proposed in the literature but all of them have fundamental flaws that hold them back from widescale implementation. We review angle-of-arrival （AOA） and angle-difference- of-arrival （ADOA） optical indoor positioning systems which have been proven to be robust, accurate, and easily implementable. We build an AOA/ADOA optical indoor positioning system out of a simple commercial high-speed camera and white light light emitting diodes （LeDs） which operate over a working area of 1 m3, and compare its performance to other indoor positioning methods. The AOA and ADOA systems achieve positioning with low errors of 1.2 and 3.7 cm, respectively.

关键词： angle-of-arrival (AOA) angle-difference-of-arrival (ADOA) indoor positioning optical positioning

Method to assess component contribution to toxicity of complex mixtures： Assessment of puberty acquisition in rats exposed to disinfection byproducts

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Journal of environmental Sciences 2017年第8期29卷 311-321页

作者： Shahid Parvez Glenn e.Rice Linda K.Teuschler Jane ellen Simmons Thomas F.Speth Susan D.richardson richard J.Miltner e.Sidney Hunter Ⅲ Jonathan G.Pressman Lillian F.Strader Gary R.Klinefelter Jerome M.Goldman Michael G.Narotsky Indiana University richard M. Fairbanks School of Public Health Department of Environmental Health Sciences IUPUI Campus Indianapolis IN 46202 USA National Center for environmental Assessment Office of Research and Development U.S. Environmental Protection Agency Cincinnati OH 45268 USA Lincla Teuschler and Associates St. Petersburg FL 33707 USA National Health and environmental effects Research Laboratory Office of Research and Development U.S. Environmental Protection Agency Research Triangle Park NC 27711 USA National Risk Management Research Laboratory Office of Research and Development U.S. Environmental Protection Agency Cincinnati OH 45268 USA Department of Chemistry and Biochemistry University of South Carolina Columbia SC 29208 USA

A method based on regression modeling was developed to discern the contribution of component chemicals to the toxicity of highly complex, environmentally realistic mixtures of disinfection byproducts（DBPs）. Chemical disinfection of drinking water forms DBP *** of concerns about possible reproductive and developmental toxicity, a whole mixture（WM） of DBPs produced by chlorination of a water concentrate was administered as drinking water to Sprague–Dawley（S–D） rats in a multigenerational study. Age of puberty acquisition,i.e., preputial separation（PPS） and vaginal opening（VO）, was examined in male and female offspring, respectively. When compared to controls, a slight, but statistically significant delay in puberty acquisition was observed in females but not in males. WM-induced differences in the age at puberty acquisition were compared to those reported in S–D rats administered either a defined mixture（DM） of nine regulated DBPs or individual DBPs. Regression models were developed using individual animal data on age at PPS or VO from the DM study. Puberty acquisition data reported in the WM and individual DBP studies were then compared with the DM models. The delay in puberty acquisition observed in the WM-treated female rats could not be distinguished from delays predicted by the DM regression model, suggesting that the nine regulated DBPs in the DM might account for much of the delay observed in the WM. This method is applicable to mixtures of other types of chemicals and other endpoints.

关键词： Drinking water disinfection byproducts DBP Puberty delay Four Lab Study Mixtures risk assessment

Senescent human hepatocytes express a unique secretory phenotype and promote macrophage migration

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World Journal of Gastroenterology 2014年第47期20卷 17851-17862页

作者： Katharine M Irvine richard Skoien Nilesh J Bokil Michelle Melino Gethin P Thomas Dorothy Loo Brian Gabrielli Michelle M Hill Matthew J Sweet Andrew D Clouston elizabeth e Powell Centre for Liver Disease Research School of MedicineThe University of QueenslandTranslational Research InstituteBrisbane 4102Australia Institute for Molecular Bio-science The University of QueenslandBrisbane 4067Australia The University of Queensland Diamantina Institute The University of Queensland Translational Research InstituteBrisbane 4102Australia Department of Gastroenterology and Hepatology Princess Alexandra HospitalBrisbane 4102Australia

AIM: To develop a model of stress-induced senescence to study the hepatocyte senescence associated secretory phenotype (SASP).

关键词： Cell aging Chemokines Hepatocytes Inflammation Liver diseases Macrophages

Identification of Conserved Regulatory elements in Mammalian Promoter Regions:A Case Study Using the PCK1 Promoter

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Genomics, Proteomics & Bioinformatics 2008年第3期6卷 129-143页

作者： George e. Liui Matthew T. Weirauch Curtis P. Van Tassell Robert W. Li Tad S. Sonstegard LakshmiK. Matukumal erin e. Connor richard W. Hanson Jianqi Yang Bovine Functional Genomics Laboratory Beltsville Agricultural Research Center Beltsville MD 20705 USA Department of Biomolecular engineering University of California Santa Cruz Santa Cruz CA 95064 USA Department of Bioinformatics and Computational Biology George Mason University Manassas VA 20110 USA Department of Biochemistry Case Western Reserve University School of Medicine Cleveland OH 44106 USA.

A systematic phylogenetic footprinting approach was performed to identify conserved transcription factor binding sites （TFBSs） in mammalian promoter regions using human, mouse and rat sequence alignments. We found that the score distributions of most binding site models did not follow the Gaussian distribution required by many statistical methods. Therefore, we performed an empirical test to establish the optimal threshold for each model. We gauged our computational predictions by comparing with previously known TFBSs in the PCK1 gene promoter of the cytosolic isoform of phosphoenolpyruvate carboxykinase, and achieved a sensitivity of 75% and a specificity of approximately 32% Almost all known sites overlapped with predicted sites, and several new putative TFBSs were also identified. We validated a predicted SP1 binding site in the control of PCK1 transcription using gel shift and reporter assays. Finally, we applied our computational approach to the prediction of putative TFBSs within the promoter regions of all available RefSeq genes. Our full set of TFBS predictions is freely available at http：//***/tfbsConsSites.

关键词： phylogenetic footprinting phosphoenolpyruvate carboxykinase transcription factor binding sites mammalian gene promoters

Geomechanical properties will constrain CO_(2)injection into the lower Ordovician Rose Run sandstone deep saline reservoir,Appalachian Basin,Kentucky,USA

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Journal of Rock Mechanics and Geotechnical engineering 2021年第5期13卷 947-960页

作者： John richard Bowersox Stephen F.Greb Junfeng Zhu David C.Harris Kentucky Geological Survey University of KentuckyLexingtonKY40506-0107USA

The Kentucky Geological Survey(KGS)1 Hanson Aggregates stratigraphic research well,Carter County,Kentucky,USA,was drilled to a total depth of 1474 m as a field-scale test of potential CO2 storage reservoir properties in the Central Appalachian *** properties of the Rose Run sandstone(upper Ordovician Knox group)were tested for its suitability as a storage reservoir.A 9.8-m thick section of the Rose Run was penetrated at 1000 m drilled depth and a whole-diameter core and rotary sidewall cores were *** porosity and permeability measured in core plugs were 9.1%and 44.6 mD,*** vertical stress gradient calculated in the wellbore was 26 MPa/*** fractures in dolomites underlying and overlying the Rose Run follow the contemporary N53e Appalachian Basin stress *** Rose Run elastic geomechanical properties were calibrated to values measured in core plugs to evaluate its fracturing risk as a CO2 storage *** Young’s modulus and Poisson’s ratio values of the Rose Run were 45 GPa and 0.23,respectively,whereas Young’s modulus and Poisson’s ratio values were 77.1 GPa and 0.28,respectively,in the overlying Beekmantown dolomite,suggesting the Rose Run may fracture if overpressured during CO2 injection but be confined by the *** compressive strength measured in core plugs found the Rose Run and Beekmantown fractured at mean axial stresses of 156.5 MPa and 282.2 MPa,respectively,confirming the Beekmantown as suitable for confining CO2 injected into the Rose Run.A step-rate test was conducted in a mechanically-isolated 18.6-m interval bracketing the Rose *** Rose Run reservoir pressure was 9.3 MPa,and fracture gradient under injection was 13.6 MPa/km,suggesting step-rate testing before CO2 injection,and subsequent pressure monitoring to ensure *** the region around the KGS 1 Hanson Aggregates well is underpressured and adjacent to faulted Precambrian basement,further research is neede

关键词： Appalachian Basin Rose Run sandstone Geomechanics Carbon sequestration Step-rate testing

Three global conditions for biodiversity conservation and sustainable use: an implementation framework

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National Science Review 2019年第6期6卷 1080-1082页

作者： Harvey Locke erle C.ellis Oscar Venter richard Schuster Keping Ma Xiaoli Shen Stephen Woodley Naomi Kingston Nina Bhola Bernardo B.N.Strassburg Axel Paulsch Brooke Williams James e.M.Watson Beyond the Aichi Targets Task Force IUCN World Commission on Protected Areas and Yellowstone to Yukon Conservation Initiative Department of Geography and environmental Systems University of Maryland Natural Resources and environmental Studies Institute University of Northern British Columbia Department of Biology Carleton University State Key Laboratory of Vegetation and environmental Change Institute of BotanyChinese Academy of Sciences IUCN World Commission on Protected Areas UN environment Programme World Conservation Monitoring Centre UNeP-WCMC

’Nature and its vital contributions to people, which together embody biodiversity and ecosystem functions and services, are deteriorating worldwide’ [1].The United Nations Convention on Biological Diversity(CBD) is intended to ensure conservation of biodiversity,its wise use, and sharing of benefits from use of genetic resources. Through

关键词： Three global conditions for biodiversity conservation and sustainable use an implementation framework

***'s In-Line Automated Oil Analysis Program

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作者： Petter A.Kristiansen richard e.Leeker NAVSeA 05N Washington Navy Yard1333 Isaac Hull Ave.Washington Navy YardDC 20376202-781-3572 American Management Systems Inc.4114 Legato RoadFairfaxVA 22033703-449-2824

The United States Navy has embarked on a program to bring real-time oil analysis results to shipboard Sailors to allowthem the ability to monitor equipment health and make maintenance *** Navy’s Automated Oil Analysis program puts insitu,oil condition and debris monitors in running machinery to perform these functions with the goal of eliminating manpowerassociated with oil sampling as well as to provide real-time tracking and trending of equipment *** Navy first established a lube oil quality management program for aviation engines in the 1960’s after a correlation was shownbetween wear metals in oil and equipment *** equipment was added to the program in the 1970’s to monitorequipment oil quality and to attempt to determine equipment impending failures before they became *** Navy recentlyreexamined its practice of sending onboard oil samples to a lab and moved away from this long-term program not because it didn’twork or didn’t have value,but because the program as executed failed to provide results in a timely enough manner to prove usefulfor shipboard equipment and maintenance *** the Naval Sea Systems Command’s program Capital Investment for Labor Reduction (CILabor),the Navy has procured,tested,and installed three separate systems in three ships to evaluate the usefulness and effectiveness of in-line systems inconditionbased maintenance at *** paper discusses the process,installation and benefits derived during the program as well asthe expected *** paper also discusses what the next steps are in the program and how the Navy intends to pursue them toreach its goal of performing maintenance based on condition.

关键词： Automated Oil Analysis (AOA) in-line oil analysis infrared gas turbineoil analysis

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水平定向钻管道穿越的设计

油气储运 1996年第12期15卷 57-60页

作者： John e.richard 孙丽华中国石油天然气管道科学研究院

用水平定向钻穿越河流是敷设管道的一种最好方法,采用这种方法虽然投资大,但管道的使用寿命长、维修率低。在水平定向钻管道穿越的设计中,必须注意以下几点:(1)在选定穿越地点后,要确定穿越管子需要几种覆盖层及其厚度,并且要给出河流... 详细信息

用水平定向钻穿越河流是敷设管道的一种最好方法,采用这种方法虽然投资大,但管道的使用寿命长、维修率低。在水平定向钻管道穿越的设计中,必须注意以下几点:(1)在选定穿越地点后,要确定穿越管子需要几种覆盖层及其厚度,并且要给出河流穿越的剖面图及管道敷设的最小标高。(2)仔细分析土壤类型,根据收集到的资料及时改变钻探位置、深度和频率。(3)利用剖面图、标高T和土工技术资料来确定管道敷设的最佳方法,该位置的定位要兼顾管道所需最小埋深和所在土壤最佳敷设方法等方面的要求。

关键词：定向钻机管道穿越施工设计油气管道

Neoarchaean-Palaeoproterozoic Mafic Dyke Swarms from the Singhbhum Granite Complex,Singhbhum Craton,eastern India:Implications for Identification of Large Igneous Provinces and Their Possible Continuation on Other Formerly Adjacent Crustal Blocks

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Acta Geologica Sinica(english edition) 2016年第S1期90卷 17-18页

作者： Rajesh K.Srivastava Ulf Soderlund richard e.ernst Sisir K.Mondal Amiya K.Samal Centre of Advanced Study in Geology Institute of ScienceBanaras Hindu University Department of Geology Lund University Department of earth Sciences Carleton University Faculty of Geology and Geography Tomsk State University Department of Geological Sciences Jadavpur University

The Singhbhum craton of the eastern India consists of the Singhbhum Granite Complex(SGC)and the Chotanagpur Gneissic Complex(CGC)separated by the Singhbhum Mobile Belt(SMB).The CGC is intruded by Mesoproterozoic as we... 详细信息

关键词： In Implications for Identification of Large Igneous Provinces and Their Possible Continuation on Other Formerly Adjacent Crustal Blocks Neoarchaean-Palaeoproterozoic Mafic Dyke Swarms from the Singhbhum Granite Complex eastern India