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About Lorentz Invariance and Gauge Symmetries: An Alternative Approach to Relativistic Gravitation

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Natural Science 2014年第16期6卷 1244-1252页

作者： richard bonneville Centre National d’Etudes Spatiales (CNES) 2 Place Maurice Quentin Paris France

An alternative presentation of a relativistic theory of gravitation, equivalent to general relativity, is given. It is based upon the restriction of the Lorentz invariance of special relativity from a global invariance to a local one. The resulting expressions appear rather simple as we consider the transformations of a local set of pseudo-orthonormal coordinates and not the geometry of a 4-dimension hyper-surface described by a set of curvilinear coordinates. This is the major difference with the usual presentations of general relativity but that difference is purely formal. The usual approach is most adequate for describing the universe on a large scale in astrophysics and cosmology. The approach of this paper, derived from particle physics and focused on local reference frames, underlines the formal similarity between gravitation and the other interactions inasmuch as they are associated to the restriction of gauge symmetries from a global invariance to a local one.

关键词： Gravitation General Relativity Gauge Symmetries

Erbium-doped TeO2-coated Si3N4 waveguide amplifiers with 5 dB net gain

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Photonics Research 2020年第2期8卷 127-134页

作者： HENRY C.FRANKIS HAMIDU M.MBONDE DAWSON B.bonneville CHENGLIN ZHANG richard MATEMAN ARNE LEINSE JONATHAN D.B.BRADLEY Department of Engineering Physics Mc Master UniversityHamilton L8S 4L7Canada Lioni X International BV Enschede AL 7500The Netherlands

We demonstrate 5dB net gain in an erbium-doped tellurium-oxide-coated silicon nitride *** amplifier design leverages the high refractive index and high gain in erbium-doped tellurite glass as well as the ultralow losses and mature,reliable,and low-cost fabrication methods of silicon nitride waveguide *** show that the waveguide platform demonstrates low background propagation losses of 0.25dB/cm based on a ring resonator device with a Q factor of 1.3×10^6 at 1640 *** measure 5dB peak net gain at 1558 nm and>3dB of net gain across the C band in a 6.7 cm long waveguide for 35 m W of launched 1470 nm pump *** per unit length of 1.7 and 1.4dB/cm is measured in a 2.2 cm long waveguide for 970 and 1470 nm pump wavelengths,*** simulations predict that>10dB gain can be achieved across the C band simply by optimizing waveguide length and fiber-chip *** results demonstrate a promising approach for the monolithic integration of compact erbium-doped waveguide amplifiers on silicon nitride chips and within silicon-based photonic integrated circuits.

关键词： waveguide pump amplifiers

The potential value of intravascular ultrasound imaging in diagnosis of aortic intramural hematoma

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Journal of Geriatric Cardiology 2011年第4期8卷 224-229页

作者： Wei Hu Francois Schiele Nicolas Meneveau Marie-France Seronde Pierre Legalery Jean-Francois bonneville Sidney Chocron Jean-Pierre Bassand Department of Cardiology Min Hang District Central HospitalShanghai 201100China Department of Cardiology University Hospital Jean MinjozBesançon 25000France Department of Radiology University Hospital Jean MinjozBesançon 25000France Department of Cardiac Surgery University Hospital Jean MinjozBesançon 25000France

Objective To evaluate the potential value of intravascular ultrasound(IVUS)imaging in the diagnosis of aortic intramural hematoma(AIH).Methods From September 2002 to May 2005,a consecutive series of 15 patients with suspected aortic dissection(AD)underwent both IVUS imaging and spiral computed tomography(CT).Six patients diagnosed as acute type B AIH by CT or IVUS composed the present study *** The study group consisted of five males and one female with mean age of 66 years *** of them had chest or back *** one patient,CT omitted a localized AIH and an associated penetrating atherosclerotic ulcer(PAU),which were detected by *** another patient,CT mistaken a partly thrombosed false lumen as an AIH,whereas IVUS detected a subtle intimal tear and slow moving blood in the false *** the four rest patients,both CT and IVUS made the diagnosis of AIH,however,IVUS detected three PAUs in three of them,only one of them was also detected by CT,and two of them escaped initial CT and were confirmed by follow up CT or magnetic resonance *** IVUS imaging is a safe examination and has high accuracy in the diagnosis of AIH,particularly for diagnosing localized AIH,distinguishing AIH with thrombosed classic AD and detecting accompanied small PAUs.

关键词： intravascular ultrasound diagnosis aortic intramural hematom

Value of intravascular ultrasound imaging in following up patients with replacement of the ascending aorta for acute type A aortic dissection

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Chinese Medical Journal 2008年第21期121卷 2139-2143页

作者： HU Wei Francois Schiele Nicolas Meneveau Marie-France Seronde Pierre Legalery Fiona Caulfield Jean-Frangois bonneville Sidney Chocron Jean-Pierre Bassand Department of Cardiology Min Hang Central Hospital Shanghai 201100 China Department of Cardiology Jean Minjoz Hospital Besancon 25000 France Department of Radiology Jean Minjoz Hospital Besancon 25000 France Department of Cardiac Surgery Jean Minjoz Hospital Besancon 25000 France

Background The value of intravascular ultrasound （IVUS） imaging in patients with replacement of the ascending aorta for acute type A aortic dissection （AD） is unknown. The purpose of this study was to assess the potential use of IVUS imaging in this setting. Methods From September 2002 to July 2005, IVUS imaging with a 9 MHz probe was performed in a series of 16 consecutive patients with suspected or established AD. This study focused on 5 of them with replacement of the ascending aorta for acute type A AD. Among these 5 patients, other imaging modalities including aortography, spiral computed tomography, magnetic resonance imaging and transesophageal echocardiography were performed in 5, 3, 3 and 1 patients, respectively. Results There were no complications related to IVUS imaging. For the replaced graft, as other imaging modalities, IVUS could identify all 5 grafts, the proximal and the distal anastomoses, and the ostia of the reimplanted coronary arteries. In 2 cases, IVUS detected 2 peri-graft pseudo-aneurysms （1 per case）, which were also detected by magnetic resonance imaging but omitted by aortography. For the residual dissection, IVUS had similar findings as other imaging modalities in detecting the patency （5/5）, the longitudinal and the circumferential extent, the thrombus （4/5）, the recurrent dissection （1/5） and an aneurysm distal to the graft （5 in 4 patients）. However, it detected more intimal tears and side branch involvements than other imaging modalities （15 vs 10 and 3 vs 1, respectively）. Conclusions In following-up patients with replacement of the ascending aorta for acute type A AD, IVUS imaging can provide complete information of the replaced graft and the residual dissection. So, IVUS imaging may be considered when the four current frequently used imaging modalities can not supply sufficient information or there are some discrepancies between them.

关键词： intravascular ultrasound aortic dissection graft

Use of a Model of a Blood-Induced Bruise for the Evaluation of Formulations on Bruising

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Journal of Cosmetics, Dermatological Sciences and Applications 2015年第1期5卷 7-14页

作者： Sophie Robin Carol Courderot-Masuyer Helene Tauzin Sylvain Harbon Marlene Chavagnac-bonneville Benoit Cadars Eric Jourdan Sandra Trompezinski Philippe Humbert Bioexigence SAS Espace LafayetteBesanconFrance Plastic Surgery Saint-Vincent ClinicBesanconFrance Laboratoire Bioderma LyonFrance Naos Group Recherche Aix-en-ProvenceFrance Laboratory of Cutaneous Biology Department of DermatologyUniversity of Franche-ComteBesanconFrance

Esthetic treatments can induce swelling and bruises. Thus, a treatment that would prevent or hasten the resolution of bruising should be very useful. Generally, the regression of bruising was conducted with patients or animals models. So we decided firstly to develop an ex vivo model in order to test antibruising properties of topical formulations and secondly to evaluate a curative effect of a cream (mixture of arnica extract and apigenin) in comparison with a positive control (vulnerary cream) and also to estimate the preventive interest of this cream. The results showed that the injection of 25 μl of blood into the dermis of skin fragments was sufficient to create a model of induced-bruise. The duration of 24 hours was chosen to compare the effects of actives on the decrease in the size of the bruise. Joint effects of a pretreatment and a treatment of a mixture of arnica extract and apigenin decreased significantly the area of bruising compared to the treatment group, the control group and the positive control group. Many topical products claim to improve bruising on their package label. Our model can demonstrate their efficacy and determinate the best topical antibruising formulation. The mechanism involved in anti-inflammatory activity of active compounds of topical formulations is often not fully understood. Our blood-induced model may bring some responses through the study of mediators of the inflammation.

关键词： Bruise Apigenin Arnica Skin Explants

Erbium-doped TeO2-coated Si3N4 waveguide amplifiers with 5 dB net gain:erratum

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Photonics Research 2020年第6期8卷 1022-1022页

作者： HENRY C.FRANKIS HAMIDU M.MBONDE DAWSON B.bonneville CHENGLIN ZHANG richard MATEMAN ARNE LEINSE JONATHAN D.B.BRADLEY Department of Engineering Physics McMaster UniversityHamiltonOntario L8S 4L7Canada LioniX International BV Enschede AL 7500The Netherlands

This erratum corrects typos that appeared in ***.8,127(2020)in the text,a figure showing the experimental setup,and a table listing the absorption and emission cross section values used in simulations.

关键词： waveguide Erbium amplifiers

视交叉海绵状血管瘤:单侧视力丧失的罕见原因

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世界核心医学期刊文摘（眼科学分册） 2005年第10期1卷 10-11页

作者： Milea D. Karachi C. bonneville F. 韩静 Service d'Ophtalmologie Groupe Hospitalier de la Piti é-Salpêtri ère 83 boulevard de l’Hopital 75013 Paris France

Introduction. Optic pathways cavernomas are rare vascular hamartomas that can present either with an acute chiasmai syndrome or slowly progressive visual loss . Observation. A 29-year-old patient presented with mild unilateral visual los s of rapid onset and monocular left temporal hemianopia. MRI disclosed a heterog enous enhancing optochiasmal lesion. Work-up found no evidence for an inflammat ory, infectious or tumoral disease and therefore a neurosurgical approach of the lesion allowed diagnosis of cavernoma, confirmed by pathological examination. S uccessful resection resulted in partial recovery of the visual field. Conclusion . Optochiasmal cavernomas are rare, removal can improve visual outcome.

关键词：海绵状血管瘤视交叉视力丧失颞侧偏盲错构瘤肿瘤疾病病理检查神经外科切除术损伤诊断

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小儿系统性红斑狼疮时的急性胰腺炎

世界核心医学期刊文摘（儿科学分册） 2006年第8期2卷 11-12页

作者： Perrin L. Giurgea I. Baudet-bonneville V. T.Ulinski 郭战宏 Department of Paediatric Nephrology Hpital Trousseau26avenue du Dr.Arnold-Netter75571 Paris Cedex 12France

Acute pancreatitis(AP)rarely complicates the clinical course of systemic lupus erythematosus(SLE).AP as the initial manifestation of SLE is exceptional,but its outcome is often *** have been suspected to play a role in the development of AP,but the therapeutic benefit seems to be far above the risk of exacerbation of pancreatic *** report a 13-y-old girl presenting with arthralgia and malaise,followed by abdominal pain,generalized oedema and haemodynamic *** CRP(325 ng/ml),serum amylase(14 000 IU/l)and lipase(2500 IU/l)levels suggested *** anuric renal failure required *** involvement suggested SLE,which was confirmed 3 d later by increased anti-ds-DNA *** methylprednisolone pulses were administered promptly,followed by oral prednisone(1.5 mg/kg/d)and six pulses of cyclophosphamide(500 mg/1.73m 2/2 wk).Mycophenolatemofetil was introduced for long-term disease *** and lipase levels decreased over *** function was normal after 3wk and proteinuria negative after 6 ***:This case suggests that steroid pulse therapy should be promptly administered if clinical and biochemical investigations suggest SLE to be responsible for *** treatment may be life saving.

关键词：急性胰腺炎(AP) 系统性红斑狼疮甲基强的松龙全身性水肿血清淀粉酶小儿冲击治疗血液动力学 DNA水平肾功能正常

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原始声色：沐浴的历史