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Optimal chunk caching in network coding-based qualitative communication

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Digital Communications and Networks 2022年第1期8卷 44-50页

作者： Lijun Dong richard Li Futurewei Technologies Inc. 2330 Central ExpresswaySanta Clara95050USA

Network processing in the current Internet is at the entirety of the data packet,which is problematic when encountering network *** newly proposed Internet service named Qualitative Communication changes the network processing paradigm to an even finer granularity,namely chunk level,which obsoletes many existing networking policies and schemes,especially the caching algorithms and cache replacement policies that have been extensively explored in Web Caching,Content Delivery Networks(CDN)or Information-Centric Networks(ICN).This paper outlines all the new factors that are brought by random linear network coding-based Qualitative Communication and proves the importance and necessity of considering them.A novel metric is proposed by taking these new factors into *** optimization problem is formulated to maximize the metric value of all retained chunks in the local storage of network nodes under the constraint of storage limit.A cache replacement scheme that obtains the optimal result in a recursive manner is proposed *** the help of the introduced intelligent cache replacement algorithm,the performance evaluations show remarkably reduced end-to-end latency compared to the existing schemes in various network scenarios.

关键词： Internet Qualitative communication New IP Chunk caching Random linear network coding End-to-end latency Cache replacement policy Degree of freedom Distance Packet size

香港特别行政区视障读者服务创新探究——以香港城市大学邵逸夫图书馆高等融合教育支持服务为例

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国家图书馆学刊 2024年第2期33卷 74-82页

作者：景祥祜王玮乐肖寒月香港城市大学邵逸夫图书馆中国香港城市大学中国

图书馆是高校教育的第二课堂,融合教育可以应用两阶段服务学习创新模式,来优化视障大学生的高等融合教育体验。香港城市大学“灯塔古迹保育研习实践项目”践行融合教育理念,邀请视障和健视大学生以灯塔共同创作出4项典型项目成果。其中... 详细信息

图书馆是高校教育的第二课堂,融合教育可以应用两阶段服务学习创新模式,来优化视障大学生的高等融合教育体验。香港城市大学“灯塔古迹保育研习实践项目”践行融合教育理念,邀请视障和健视大学生以灯塔共同创作出4项典型项目成果。其中《西屿塔灯历险》案例具体展示了两阶段服务学习的开展方式,探究图书馆在高等融合教育支持服务体系下的视障读者服务创新。图3。表1。参考文献22。

关键词：高等融合教育服务学习视障读者高等教育信息素养框架

Optimal orientations of discrete global grids and the Poles of Inaccessibility

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International Journal of Digital Earth 2020年第7期13卷 803-816页

作者： richard Barnes Energy&Resources Group BerkeleyUSA Electrical Engineering&Comptuer Science BerkeleyUSA

Spatial analyses involving binning often require that every bin have the same area,but this is impossible using a rectangular grid laid over the Earth or over any projection of the *** global grids use hexagons,triangles,and diamonds to overcome this issue,overlaying the Earth with equally-sized *** discrete global grids are formed by tiling the faces of a ***,the orientations of these polyhedra have been chosen to satisfy only simple criteria such as equatorial symmetry or minimizing the number of vertices intersecting ***,projection distortion and singularities in discrete global grids mean that such simple orientations may not be sufficient for all use ***,I present an algorithm for finding suitable orientations;this involves solving a nonconvex optimization *** a side-effect of this study I show that Fuller’s Dymaxion map corresponds closely to one of the optimal orientations I find.I also give new high-accuracy calculations of the Poles of Inaccessibility,which show that Point Nemo,the Oceanic Pole of Inaccessibility,is 15 km farther from land than previously recognized.

关键词： Discrete grid geographic information system(GIS) geoinformatics supercomputer projections spatial statistics

Design of low-energy on-chip electro-optical 1 × M wavelength-selective switches

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Photonics Research 2017年第4期5卷 340-345页

作者： richard SOREF Department of Engineering The University of Massachusetts at Boston

A theoretical design is presented for a 1 × M wavelength-selective switch(WSS) that routes any one of N incoming wavelength signals to any one of M output ports. This planar on-chip device comprises of a 1 × N demultiplexer, a group of N switching "trees" actuated by electro-optical or thermo-optical means, and an M-fold set of N × 1multiplexers. Trees utilize 1 × 2 switches. The WSS insertion loss is proportional to [log_2(M+N +1)]. Along with cross talk from trees, cross talk is present at each cross-illuminated waveguide intersection within the WSS, and there are at most N-1 such crossings per path. These loss and cross talk properties will likely place a practical limit of N=M=16 upon the WSS size. By constraining the 1 × 2 switching energy to^1 f J∕bit, we find that resonant, narrowband 1 × 2 switches are required. The 1 × 2 devices proposed here are nanobeam Mach–Zehnders and asymmetric contra-directional couplers with grating assistance.

关键词： Design of low-energy on-chip electro-optical 1 M wavelength-selective switches WSS

Associations of Gestational Exposure to Air Pollution and Polycyclic Aromatic Hydrocarbons with Placental Inflammation

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Environment & Health 2024年第9期2卷 672-680页

作者： Emily A.Craig Yan Lin Yihui Ge Xiangtian Wang Susan K.Murphy Donald K.Harrington richard K.Miller Sally W.Thurston Philip K.Hopke Emily S.Barrett Thomas G.O’Connor David Q.Rich Junfeng Zhang Nicholas School of the Environment&Duke Global Health Institute Duke UniversityDurhamNorth Carolina 27708United States Department of Psychiatry University of Rochester School of Medicine and DentistryRochesterNew York 14642United States Department of Obstetrics and Gynecology University of Rochester School of Medicine and DentistryRochesterNew York 14642United States Department of Environmental Medicine and Department of Pediatrics University of Rochester School of Medicine and DentistryRochesterNew York 14642United States Department of Psychology University of RochesterRochesterNew York 14642United States Department of Biostatistics and Computational Biology and Department of Environmental Medicine University of Rochester School of Medicine and DentistryRochesterNew York 14642United States Department of Public Health Sciences University of Rochester School of Medicine and DentistryRochesterNew York 14642United States Department of Biostatistics and Epidemiology Rutgers School of Public HealthPiscatawayNew Jersey 08854United States Department of Psychiatry and Department of Neuroscience University of Rochester School of Medicine and DentistryRochesterNew York 14642United States Department of Public Health Sciences Department of Medicineand Department of Environmental MedicineUniversity of Rochester School of Medicine and DentistryRochesterNew York 14642United States

Restricted fetal growth(RFG)is a leading contributor to perinatal mortality and has been associated with gestational exposure to air pollution,such as fine particulate matter(PM_(2.5)),nitrogen dioxide(NO2),and polycyclic aromatic hydrocarbons(PAHs).This study examines the association between trimester-specific and weekly means of air pollution throughout gestation and placental inflammatory markers at *** a prospective cohort study of 263 pregnant women in Rochester,NY,we measured interleukin-6(IL-6)and tumor necrosis factor-alpha(TNF-α)in placental tissue and estimated gestational exposure to PM_(2.5)and NO_(2)using a high-resolution spatial-temporal *** to PAHs was estimated using urinary 1-hydroxypyrene(1-OHP)concentrations collected once per *** distributed lag models with a penalized spline function,each interquartile range(2.6μg/m^(3))increase in PM_(2.5)concentration during gestational weeks 6−11 was associated with decreased placental IL-6 levels(−22.2%,95%CI:−39.0%,−0.64%).Using multiple linear regression models,each interquartile range increase of 1-OHP was associated with an increase in TNF-αin the first trimester(58.5%,95%CI:20.7%,74.2%),third trimester(22.9%,95%CI:0.04%,49.5%),and entire pregnancy(29.6%,95%CI:3.9%,60.6%).Our results suggest gestational exposure to air pollution may alter the inflammatory environment of the placenta at delivery.

关键词： pregnancy air pollution PAHs placenta tumor necrosis factor interleukin

Soundscapes and the sense of hearing of fishes

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Integrative Zoology 2009年第1期4卷 26-32页

作者： richard FAY Parmly Hearing Institute Loyola University ChicagoChicagoUSA

Underwater soundscapes have probably played an important role in the adaptation of ears and auditory systems of fishes throughout evolutionary time,and for all *** sounds probably contain important information about the environment and about most objects and events that confront the receiving fish so that appropriate be-havior is *** example,the sounds from reefs appear to be used by at least some fishes for their orientation and *** sorts of environmental sounds should be considered much like“acoustic daylight,”that continuously bathes all environments and contain information that all organisms can potentially use to form a sort of image of the *** present,however,we are generally ignorant of the nature of ambient sound fields impinging on fishes,and the adaptive value of processing these fields to resolve the multiple sources of *** field has focused almost exclusively on the adaptive value of processing species-specific communication sounds,and has not considered the informational value of ambient“noise.”Since all fishes can detect and process acoustic particle motion,including the directional characteristics of this motion,underwater sound fields are potentially more complex and information-rich than terrestrial acoustic *** capacities of one fish species(goldfish)to receive and make use of such sound source information have been demonstrated(sound source seg-regation and auditory scene analysis),and it is suggested that all vertebrate species have this capacity.A call is made to better understand underwater soundscapes,and the associated behaviors they determine in fishes.

关键词： acoustic daylight auditory scene analysis soundscape sound source segregation.

Combining scanning tunneling microscope (STM) imaging and local manipulation to probe the high dose oxidation structure of the Si(111)-7×7 surface

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Nano Research 2020年第1期13卷 145-150页

作者： Dogan Kaya richard J.Cobley richard E.Palmer Department of Electronics and Automation Vocational School of AdanaCukurova University01160CukurovaAdanaTurkey Nanoscale Physics Research Laboratory School of Physics and AstronomyUniversity of BirminghamEdgbastonBirminghamB152TTUK College of Engineering Swansea UniversityBay CampusFabian WaySwanseaSA18ENUK

Understanding the atomistic formation of oxide layers on semiconductors is important for thin film fabrication,scaling down conventional devices and for the integration of emerging research ***,the initial oxidation of Si(111)is studied using the scanning tunneling *** to the complete saturation of the silicon surface with oxygen,we are able to probe the atomic nature of the oxide layer *** establish the threshold for local manipulation of inserted oxygen sites to be+3.8 *** by combining imaging with local atomic manipulation are we able to determine whether inserted oxygen exists beneath surface-bonded oxygen sites and differentiate between sites that have one and more than one oxygen atom inserted beneath the *** to the creation of the thin oxide film we observe a flip in the manipulation rates of inserted oxygen sites consistent with more oxygen inserting beneath the silicon surface.

关键词： scanning tunneling microscopy(STM) local manipulation Si(111) oxidation

Pleomorphic Nasopharyngeal Liposarcoma: An Aggressive Tumor

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International Journal of Otolaryngology and Head & Neck Surgery 2024年第1期13卷 11-15页

作者： Mame Sanou Diouf Sall Ahmadou Cheikhou Ndiaye Ciré Thiam Amadou Abdoulaye Diop Deguenonvo richard Edouard Alain Diom Evelyne Siga Ndiaye Malick Diallo Bay Karim Diouf Raymond ENT and Cervicofacial Surgery Department Idrissa Pouye General Hospital Grand-Yoff Dakar Senegal ENT Department Diamniadio Children’s Hospital Dakar Senegal ENT clinic Lamine Sine Diop Dakar Senegal ENT Department and Cervico-Facial Surgery H&#244pital de la paix Ziguinchor Senegal ENT and Cervicofacial Surgery Department Albert Royer Children’s Hospital Dakar Senegal

Nasopharyngeal liposarcoma is an extremely rare clinical entity. Less than ten cases have been reported in the literature. It mainly occurs in humans. The non-specificity of the clinical and radiological signs explains the difficulty of the diagnosis confirmed by anatomopathological and immunohistochemical examinations. Its pathogenesis remains obscure and often correlates with genetic abnormalities. Pleomorphic liposarcoma is its rarest subtype, remarkable for its aggressiveness and rapidity of growth. Complete surgical excision remains the treatment of choice. We report a case of liposarcoma whose diagnosis was made during histological examination coupled with immunohistochemistry. .

关键词： Liposarcoma Nasopharynx Pathology Immunohistochemistry

Genomics-driven derivatization of the bioactive fungal sesterterpenoid variecolin:Creation of an unnatural analogue with improved anticancer properties

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Acta Pharmaceutica Sinica B 2024年第1期14卷 421-432页

作者： Dexiu Yan Jemma Arakelyan Teng Wan Ritvik Raina Tsz Ki Chan Dohyun Ahn Vladimir Kushnarev Tsz Kiu Cheung Ho Ching Chan Inseo Choi Pui Yi Ho Feijun Hu Yujeong Kim Hill Lam Lau Ying Lo Law Chi Seng Leung Chun Yin Tong Kai Kap Wong Wing Lam Yim Nikolay S.Karnaukhov richard Y.C.Kong Maria V.Babak Yudai Matsuda Department of Chemistry City University of Hong KongHong Kong SARChina iGEM Team“VarieCure” City University of Hong KongHong Kong SARChina Department of Biomedical Engineering City University of Hong KongHong Kong SARChina Moscow Clinical Research Center Named After A.S.Loginov Moscow 111123Russian Federation

A biosynthetic gene cluster for the bioactive fungal sesterterpenoids variecolin(1)and variecolactone(2)was identified in Aspergillus aculeatus ATCC *** production of 1 and 2 was achieved in Aspergillus oryzae by expressing the sesterterpene synthase VrcA and the cytochrome P450 ***,the replacement of VrcB with homologous P450s from other fungal terpenoid pathways yielded three new variecolin analogues(5-7).Analysis of the compounds’anticancer activity in vitro and in vivo revealed that although 5 and 1 had comparable activities,5 was associated with significantly reduced toxic side effects in cancer-bearing mice,indicating its potentially broader therapeutic *** study describes the first tests of variecolin and its analogues in animals and demonstrates the utility of synthetic biology for creating molecules with improved biological activities.

关键词： Animal studies Anticancer properties Biosynthesis Natural products Sesterterpenoids Synthetic biology Terpene synthases Variecolin