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Hepatobiliary & Pancreatic Diseases International 2024年第5期23卷 533-534页

作者： Karin KY Ho Sui Ling Sin kin Pan Au Henry HY Lee Daniel TL Chan Albert Chan Department of Surgery The University of Hong Kong102 Pok Fu Lam RoadHong KongChina Department of Surgery Yan Chai Hospital7 Yan Chai StreetHong KongChina State Key Laboratory of Liver Research(Li Ka Shing Faculty of Medicine The University of Hong Kong)102 Pok Fu Lam RoadHong KongChina

To the Editor : Barcelona Clinic Liver Cancer(BCLC) Stage C hepatocellular carcinoma(HCC) with vascular invasion has been considered unresectable. However, the curative rate from systemic treatment is rather dismal. Even with the use of immunotherapy, complete remission is less than 10% [ 1 ]. On the contrary, recent advances in transplant oncology, especially in the application of liver transplant-related surgical techniques in complex liver resections, make the operation possible for patients with locally advanced HCC who were previously considered to be unresectable [ 2 ]. We hereby present the surgical management of a patient with giant HCC in right liver lobe with inferior vena cava(IVC) invasion.

关键词： invasion vena Liver

A Nonlinear Interval Portfolio Selection Model and Its Application in Banks

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Journal of Systems Science & Complexity 2018年第3期31卷 696-733页

作者： yan Dawen HU Yaxing LAI kin Keung Faculty of Management and Economics Dalian University of Technology Dalian 116024 China School of Mathematical Science Dalian University of Technology Dalian 116024 China Bank of Dalian Dalian 116001 China School of Mathematical Science Dalian University of Technology Dalian 116024 China International Business School Shaanxi Normal University Xi'an 710062 China College of Management Xidian University Xi'an 710126 China

In classical Markowitz＇s Mean-Variance model, parameters such as the mean and covari- ance of the underlying assets＇ future return are assumed to be known exactly. However, this is not always the case. The parameters often correspond to quantities that fall within a range, or can be known ambiguously at the time when investment decision must be made. In such situations, investors determine returns on investment and risks etc. and make portfolio decisions based on experience and economic wisdom. This paper tries to use the concept of interval numbers in the fuzzy set theory to extend the classical mean-variance portfolio selection model to a mean-downside semi-variance model with consideration of liquidity requirements of a bank. The semi-variance constraint is employed to control the downside risk, filling in the existing interval portfolio optimization model based on the linear semi-absolute deviation to depict the downside risk. Simulation results show that the model behaves robustly for risky assets with highest or lowest mean historical rate of return and the optimal investment proportions have good stability. This suggests that for these kinds of assets the model can reduce the risk of high deviation caused by the deviation in the decision maker＇s experience and economic wisdom.

关键词： Downside-risk management interval return portfolio selection semi-variance simulation.

Diagnosis,treatment and prevention of severe acute respiratory syndrome coronavirus 2 infection in children:experts'consensus statement updatedforthe Omicron variant

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World Journal of Pediatrics 2024年第3期20卷 272-286页

作者： Rong-Meng Jiang Zheng-De Xie Yi Jiang Xiao-Xia Lu Run-Ming Jin Yue-Jie Zheng Yun-Xiao Shang Bao-Ping Xu Zhi-Sheng Liu Gen Lu Ji-Kui Deng Guang-Hua Liu Xiao-Chuan Wang Jian-She Wang Lu-Zhao Feng Wei Liu Yi Zheng Sai-Nan Shu Min Lu Wan-Jun Luo Miao Liu Yu-Xia Cui Le-Ping Ye A-Dong Shen Gang Liu Li-Wei Gao Li-Juan Xiong yan Bai Li-Kai Lin Zhuang Wei Feng-Xia Xue Tian-You Wang Dong-Chi Zhao Jian-Bo Shao Daniel Kwok-keung Ng Gary Wing-kin Wong Zheng-yan Zhao Xing-Wang Li Yong-Hong yang Kun-Ling Shen Diagnosis and Treatment Center of Infectious Diseases Beijing Ditan HospitalCapital Medical UniversityBeijing 100015China Beijing Key Laboratory of Pediatric Respiratory Infection Diseases Key Laboratory of Major Diseases in ChildrenMinistry of EducationNational Clinical Research Center for Respiratory DiseasesResearch Unit of Critical Infection in ChildrenChinese Academy of Medical Sciences2019RU016Laboratory of Infection and VirologyBeijing Pediatric Research InstituteBeijing Children's HospitalCapital Medical UniversityNational Center for Children's HealthBeijing 100045China Department of Pediatrics Renmin Hospital of Wuhan UniversityWuhan 430060China Department of Respiratory Wuhan Children's HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430016China Department of Pediatrics Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Department of Respiratory Shenzhen Children's HospitalShenzhen 518038China Department of Pediatric Respiratory Shengjing Hospital Affiliated to China Medical UniversityShenyang 110004China Department of Respiratory Beijing Children's HospitalCapital Medical UniversityNational Clinical Research Center for Respiratory DiseasesNational Center for Children's HealthBeijing 100045China Department of Neurology Wuhan Children's HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430016China Department of Respiratory Guangzhou Women and Children's Medical CenterGuangzhou 510623China Department of Infectious Diseases Shenzhen Children's HospitalShenzhen 518038China Department of Pediatrics Fujian Branch of Shanghai Children's Medical CenterFujian Children's HospitalFuzhou350005China Department of Clinical Immunology and Allergy Children's Hospital of Fudan UniversityNational Center for Children's HealthShanghai 201102China Department of Infectious Diseases Children's Hospital of Fudan UniversityNational Center for Children's Health.Shanghai

It has been more than 3 years since the novel coronavirus(SARS-CoV-2)pandemic raged *** coronavirus disease 2019(COVID-19)has greatly influenced human *** to data from the World Health Organization(WHO),there were ove... 详细信息

关键词： prevention infection statement

Current status of associating liver partition with portal vein ligation for staged hepatectomy: Comparison with two-stage hepatectomy and strategies for better outcomes

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World Journal of Gastroenterology 2019年第43期25卷 6373-6385页

作者： kin Pan Au Albert Chi yan Chan Department of Surgery Queen Mary HospitalHong KongChina Department of Surgery and State Key Laboratory for Liver Research The University of Hong KongHong KongChina

Since its introduction in 2012,associating liver partition with portal vein ligation for staged hepatectomy(ALPPS)has significantly expanded the pool of candidates for liver *** offers patients with insufficient liver function a chance of a *** is most controversial when its high morbidity and mortality is *** mortality is usually a result of posthepatectomy liver failure and can be minimized with careful patient *** patients have limited reserve for tolerating the demanding *** with colorectal liver metastasis have normal liver and are ideal *** for cholangiocarcinoma is technically challenging and associated with fair *** with hepatocellular carcinoma have chronic liver disease and limited parenchymal ***,in selected patients with limited hepatic fibrosis satisfactory outcomes have been *** the inter-stage period,serum bilirubin and creatinine level and presence of surgical complication predict mortality after stage *** growth rate and hepatobiliary scintigraphy also guide the decision whether to postpone or omit stage II *** outcomes of ALPPS have been improved by a combination of technical *** patients with challenging anatomy,partial ALPPS potentially reduces morbidity,but remnant hypertrophy may compare unfavorably to a complete *** compared to conventional two-stage hepatectomy with portal vein embolization or portal vein ligation,ALPPS offers a higher resection rate for colorectal liver metastasis without increased morbidity or *** ALPPS has obvious theoretical oncological advantages over two-stage hepatectomy,the long-term outcomes are yet to be determined.

关键词： Associating liver partition with portal vein ligation for staged hepatectomy Two-stage hepatectomy Patient selection Surgical outcomes

Deep learning for diagnosis of precancerous lesions in upper gastrointestinal endoscopy:A review

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World Journal of Gastroenterology 2021年第20期27卷 2531-2544页

作者： Tao yan Pak kin Wong Ye-Ying Qin School of Mechanical Engineering Hubei University of Arts and ScienceXiangyang 441053Hubei ProvinceChina Department of Electromechanical Engineering University of MacaoTaipa 999078MacaoChina

Upper gastrointestinal(GI)cancers are the leading cause of cancer-related deaths *** identification of precancerous lesions has been shown to minimize the incidence of GI cancers and substantiate the vital role of screening ***,unlike GI cancers,precancerous lesions in the upper GI tract can be subtle and difficult to *** intelligence techniques,especially deep learning algorithms with convolutional neural networks,might help endoscopists identify the precancerous lesions and reduce interobserver *** this review,a systematic literature search was undertaken of the Web of Science,PubMed,Cochrane Library and Embase,with an emphasis on the deep learning-based diagnosis of precancerous lesions in the upper GI *** status of deep learning algorithms in upper GI precancerous lesions has been systematically *** challenges and recommendations targeting this field are comprehensively analyzed for future research.

关键词： Artificial intelligence Deep learning Convolutional neural network Precancerous lesions Endoscopy

Successful conservative management of Class III iatrogenic aortic dissection

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Journal of Geriatric Cardiology 2018年第3期15卷 235-237页

作者： Wai kin Chi Gary Tse Bryan PY yan Department of Medicine and Therapeutics Faculty of Medicine The Chinese University of Hong Kong Hong Kong China Division of Cardiology Prince of Wales Hospital Shatin Hong Kong China Li Ka Shing Institute of Health Sciences Faculty of Medicine The Chinese University of Hong Kong Hong Kong China

Iatrogenic aortic dissection （IAD） is a rare complication of percutaneous coronary intervention （PCI） with an estimated incidence of 0.02%--0.04%. lAD occurs more frequently in the setting of urgent PCI for acute myocardial infarction （AMI）（0.19%） than for elective procedures （0.01%）.[11 The mortality risk associated with IAD is high （16%） and is comparable to that for spontaneous aortic dissection （16%）.Urgent surgery is the treatment of choice for extensive dissection or hemodynamic instability. In this report, we present a case of severe IAD that was managed conservatively with good clinical outcome.

关键词： Conservative management Iatrogenic aortic dissection Percutaneous coronary intervention

Optical coherence tomography-guided percutaneous transluminal angioplasty in renal artery fibromuscular dysplasia

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Journal of Geriatric Cardiology 2020年第3期17卷 173-174页

作者： Wai kin Chi Tan Guang Ming Bryan P yan Division of Cardiology Department of Medicine and TherapeuticsPrince of Wales Hospitalthe Chinese University of Hong KongHong KongChina

A 40-year-old woman was referred for resistant hypertension despite three anti-hypertensive medications including a diuretic at maximum tolerated *** has no family history of fibromuscular dysplasia(FMD).Contrast-enha... 详细信息

关键词： Fibromuscular dysplasia Optical coherence tomography Renal artery stenosis

‘One Health' for the people of Hong Kong and the world

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Science China(Life Sciences) 2016年第10期59卷 1068-1070页

作者： kin-Hang Kok Hei-Man Vincent Tang Dong-yan Jin Department of Biochemistry University of Hong Kong

Translational medicine refers to the conversion of scientific discoveries into improvements in medical practice. ＇From bench to bedside and back＇ is a phrase that is often used to describe the two-way information flow in translational medicine. On one hand, scientists working at the bench make new discoveries that enable clinicians to revolutionize patient care, while on the other hand, clinical investigations at the bedside provide new knowledge about diseases, which stimulate basic research at the bench.

关键词：世界香港健康科学发现临床医生临床调查基础研究信息流

Specializing liquid electrolytes and carbon-based materials in EDLCs for low-temperature applications

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Journal of Energy Chemistry 2022年第5期31卷 580-602页

作者： Pui-yan Hung Huihui Zhang Han Lin Qiaoshi Guo kin-tak Lau Baohua Jia Centre for Translational Atomaterials Faculty of ScienceEngineering and TechnologySwinburne University of TechnologyMelbourne VIC 3122Australia SEMITRI Pty Ltd. Watson NorthMelbourne VIC 3122Australia

Electric double-layer capacitors(EDLCs) are emerging technologies to meet the ever-increasing demand for sustainable energy storage devices and systems in the 21 st Century owing to their advantages such as long lifetime, fast charging speed and environmentally-friendly nature, which play a critical part in satisfying the demand of electronic devices and systems. Although it is generally accepted that EDLCs are suitable for working at low temperatures down to-40℃, there is a lack of comprehensive review to summarize the quantified performance of EDLCs when they are subjected to low-temperature environments. The rapid and growing demand for high-performance EDLCs for auxiliary power systems in the aeronautic and aerospace industries has triggered the urge to extend their operating temperature range,especially at temperatures below-40℃. This article presents an overview of EDLC’s performance and their challenges at extremely low temperatures including the capability of storing a considerable amount of electrical energy and maintaining long-term stability. The selection of electrolytes and electrode materials is crucial to the performance of EDLCs operating at a desired low-temperature range. Strategies to improve EDLC’s performance at extremely low temperatures are discussed, followed by the future perspectives to motivate more future studies to be conducted in this area.

关键词： Electric double-layer capacitors(EDLCs) Liquid electrolytes Carbon-based materials Low-temperature applications