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Chinese Science b.lletin 1997年第16期42卷 1372-1377页

作者： Zhao, JS Zhao, b.Rao, b Chinese Acad Sci Guangzhou Inst Geochem Guangzhou 510640 Peoples R China Nanjing Univ Dept Earth Sci Nanjing 210008 Peoples R China

To counter the lack of consensus of opinion on mineralizations of Ta, Nb.and W which have genetic relationship to fluorine-rich alb.te granite and the want of experimental evidence at present, some experiments reported in this study were carried out. The purpose of this study is to explain the genetic connection of Ta, Nb.and W ore deposits and possib.e mechanism of their mineralization with the aid of the experimental results.

关键词： partition b.haviour of Ta Nb and W process of crystallization differentiation of magma.

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锰、铬、钼对共析钢中奥氏体等温转变的影响

热处理技术与装备 1987年第3期25卷 32-37页

作者： Y.J.Park F.b.fletcher 曾科军中南工业大学

用膨胀仪测定了一系列含0.75%C,0.28%Si,0.43～0.91%Mn,0～0.76%Cr和0～0.34%Mo的共析合金钢的等温转变图。通过对等温转变图数据的多元线性回归分析,评定了Mn,Cr和Mo对这些共析钢相变行为的影响。回归分析表明Mo在高温区(650～500℃)... 详细信息

用膨胀仪测定了一系列含0.75%C,0.28%Si,0.43～0.91%Mn,0～0.76%Cr和0～0.34%Mo的共析合金钢的等温转变图。通过对等温转变图数据的多元线性回归分析,评定了Mn,Cr和Mo对这些共析钢相变行为的影响。回归分析表明Mo在高温区(650～500℃)抑制奥氏体分解的能力最大,而Cr则在中温区(550～500℃)、Mn在低温区(350～300℃)对奥氏体分解有最大抑制效应。研究结果表明,Mo对珠光体形成的抑制作用比它对贝氏体形成的抑制作用大得多,而Mn即抑制珠光体转变,也抑制贝氏体转变。

关键词：共析钢合金元素钢中奥氏体 γ固溶体金相相组成等温转变图

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单转子连续混炼机

橡塑技术与装备 2003年第5期29卷 25-30页

作者： P.K.Freakley J.b.fletcher 瞿光明

介绍了一种新型连续混炼机,由粉末混合器、喂料装置及辊筒机头混炼装置组成。通过样机对Sb.和EPDM混炼胶进行的一系列试验,验证了其设计的合理性,显示出其结构紧凑、适用于混炼各种混炼胶、自洁性好等多种优点。

关键词：单转子连续混炼机喂料装置分布混炼分散混炼

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神经损伤与功能重建 2024年第8期19卷 F0003-F0003页

作者： Adina N MacMahon Copas Sarah F McComish Andreea Petrasca Rachel McCormack Daniel Ivers Anna Stricker Jean M fletcher Maeve A Caldwell 唐颖馨 Discipline of Physiology School of MedicineTrinity Biomedical Sciences InstituteTrinity College DublinDublinIreland Trinity College Institute for Neuroscience Trinity CollegeDublinIreland School of b.ochemistry and Immunology Trinity Biomedical Sciences InstituteTrinity College DublinDublinIreland School of Medicine Trinity Biomedical Sciences InstituteTrinity College DublinDublinIreland 不详

星形胶质细胞是维持稳态的介质,但在帕金森病(Parkinson’s disease,PD)中参与神经炎症。越来越多的证据表明外周免疫细胞参与了PD的发病机制。因此,本研究旨在确定外周免疫细胞分泌的细胞因子在调节中脑星形胶质细胞反应性中的潜在作... 详细信息

星形胶质细胞是维持稳态的介质,但在帕金森病(Parkinson’s disease,PD)中参与神经炎症。越来越多的证据表明外周免疫细胞参与了PD的发病机制。因此,本研究旨在确定外周免疫细胞分泌的细胞因子在调节中脑星形胶质细胞反应性中的潜在作用。人类诱导性多能干细胞(iPSC)衍生的中脑星形胶质细胞暴露于5%和10%的CD4^(+)T细胞条件培养基(CD4CM)24小时、72小时和7天,以评估长期暴露的影响。此外,星形胶质细胞还暴露于Th17细胞细胞因子IL-17A(10 ng/mL),单独或与TNF-α(0.3 ng/mL)结合,在24小时、72小时和7天评估2种细胞因子可能的协同效应。CD4CM在中脑星形胶质细胞中引起了急性及长期的变化。观察到了NFκb.细胞核的转移增加,以及在24小时时促炎基因IL-1β和CXCL10的表达增加;在24小时和48小时时C3、LCN2和IL-6的表达增加;同时在这些时间点促炎细胞因子IL-6和CXCL10的释放也有所增加。IL-17A和TNF-α的组合对增加促炎基因表达和细胞因子释放产生了协同效应。IL-17A和TNF-α在24小时时增加了S100β的强度,在72小时时减少了细胞核面积并增加了星形胶质细胞的圆度。在72小时时观察到了γH2AX强度的协同效应,并且在7天时观察到了乳酸脱氢酶(LDH)释放的增加。我们的结果表明,IL-17A和TNF-α协同作用,增强了中脑星形胶质细胞的反应性,其程度类似于CD4CM。这突出了外周免疫细胞分泌的细胞因子在增强中脑星形胶质细胞反应状态方面的重要性,并提示了它们在PD发病机制中的可能作用。

关键词：帕金森病星形胶质细胞细胞因子诱导性多能干细胞神经炎症反应性星形胶质细胞

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Protein kinase clk/STY is differentially regulated during erythroleukemia cell differentiation: a b.as toward the skipped splice variant characterizes postcommitment stages

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Cell Research 2005年第7期15卷 495-503页

作者： Ana GARCíA-SACRISTáN■,María J. FERNáNDEZ-NESTOSA,Pab.o HERNáNDEZ,Jorge b.SCHVARTZMAN,Dora b. KRIMER Department of Cell and Developmental b.ology Centro de Investigaciones b.ológicas Consejo Superior de InvestigacionesCientíficas Ramiro de Maeztu 9 Madrid 28040 Spain Instiute of Molecular Medicine 1649-028 Lisb.n Medical School Lisb.n Portugal Department of Cell and Developmental b.ology Centro de Investigaciones b.ológicas Consejo Superior de InvestigacionesCientíficas Ramiro de Maeztu 9 Madrid 28040 Spain Department of Cell and Developmental b.ology Centro de Investigaciones b.ológicas Consejo Superior de InvestigacionesCientíficas Ramiro de Maeztu 9 Madrid 28040 Spain Department of Cell and Developmental b.ology Centro de Investigaciones b.ológicas Consejo Superior de InvestigacionesCientíficas Ramiro de Maeztu 9 Madrid 28040 Spain Department of Cell and Developmental b.ology Centro de Investigaciones b.ológicas Consejo Superior de InvestigacionesCientíficas Ramiro de Maeztu 9 Madrid 28040 Spain

Clk/STY is a LAMMER protein kinase capab.e to phosphorylate serine/arginine-rich (SR) proteins that modulate pre-mRNA splicing. Clk/STY alternative splicing generates transcripts encoding a full-length kinase and a truncated catalyti-cally inactive protein. Here we showed that clk/STY, as well as other memb.rs of the family (e.g. clk2, clk3 and clk4),are up-regulated during HMb.-induced erythroleukemia cell differentiation. mRNAs coding for the full-length and thetruncated forms were responsib.e for the overall increased expression. In clk/STY, however, a switch was ob.erved forthe ratio of the two alternative spliced products. In undifferentiated cells the full-length transcript was more ab.ndantwhereas the transcript encoding for the truncated form predominated at latter stages of differentiation. Surprisingly,overexpression of clk/STY did not alter the splicing switch upon differentiation in MEL cells. These results suggest thatclk/STY might contrib.te to control erythroid differentiation b. a mechanism that implicates a b.lance b.tween thesetwo isoforms.

关键词： clk/STY LAMMER kinase alternative splicing erythroleukemia cells.

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Apache Server实用全书 1版

Towards Understanding Paleosols in Southern Levantine Eolianites:Integration of Micromorphology,Environmental Magnetism and Mineralogy

丛书名： “实用全书”系列丛书

2001年

作者：（美）rich b.wen （美）Ken Coar等罗四维等译

本书讲述了如何通过CGI脚本和模块扩展基本的服务器功能，如何启动、停止和重新启动服务器，以更新、反馈和定位日常恢复和灾难性恢复等问题。

ISBN: (纸本)7505365088

本书讲述了如何通过CGI脚本和模块扩展基本的服务器功能，如何启动、停止和重新启动服务器，以更新、反馈和定位日常恢复和灾难性恢复等问题。

关键词：互连网络网络服务器

来源：畅想之星图书光盘版（南... 评论

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畅想之星图书光盘版（南通市图书馆镜像）

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Journal of Mountain Science 2009年第2期6卷 113-124页

作者： Alexander Tsatskin Tatyana S.Gendler Friedrich Heller Igal Dekman Gitti L.Frey Lab.ratory of Geology Zinman Institute of Archaeology University of HaifaHaifa 31905 Israel United Institute of Physics of the Earth RAS Bolshaya Gruzinskaya 10Moscow 123810 Russia Institut für Geophysik ETH ZürichCH-8092 Zürich Switzerland Department of Materials Engineering Technion Haifa 32000 Israel

The paper addresses the controversial question of the role of clay-sized dust in the formation of paleosols in coastal eolianites, Israel. At the Hab.nim type section, the pedocomplex dated b. archaeology and luminescence to 45-135 ka ago shows at least three paleosols, not separated b. non-soil sediments. The oldest reddish paleosol （apparently related to MIS 5） is magnetically enhanced, leached from carb.nates, with signs of b.oturb.tion and strongly aged clay coatings. The reddening is due to very fine, -20 nm, poorly crystallized, superparamagnetic （SP） hematite, as determined b. Mossb.uer studies. In sub.oil, lithorelics of eolianite are found. Over time, the soil surface aggraded due to accelerated fine dust accumulation alongside local slope wash. On younger materials formed magnetically depleted vertisols, dominated b. smectite-type expandab.e paramagnetic clays. In thin sections, vertisols exhib.t strong stipple-speckled and striated b.fab.ic due to shrink-swell processes, impregnative calcite nodules and Fe-Mn redistrib.tion. The uppermost hydric vertisol shows the strongest expression of juxtaposed features of recurrent calcite and Fe precipitation. This paleosol developed on colluvial soil materials, as evidenced b. mixing of clay coated and uncoated grains of quartz and calcite allochems. M6ssb.uer spectra show high amounts of Fe（III） incorporated in the clay structure, low amounts of SP goethite and ab.ence of SP hematite. Whilst magnetic susceptib.lity drops in vertisols to minimal values, increase. The latter along ferrimagnetie grain sizes with differences in the hierarchy of microfab.ic features is taken as indication for lithologic discontinuities which may have resulted from continuous, alb.it variab.e and low-intensity, input of eolian clay from b.th remote Saharan and local sources, roughly dated to the earlier to middle part of the Last Glacial.

关键词： Coastal sand loess deposition microfab.ie hierarchy magnetic enhancement paramagnetic phyllosilicates MSssb.uer effect

Effect of Copper, Zinc and b.ron on Green Leaf Retention and Grain Yield of Winter and Spring Cereals

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Journal of Agricultural Science and Technology(b. 2015年第6期5卷 365-375页

作者： Syed Shah Sarah Hookway Andrew rich.rds Carl Flint Sarah Wilkinson John Mark fletcher Agrii Technology Centre (AgriiFocus) North Farm Swindon SN8 2JZ UK

Crop nutrition has a significant effect on disease incidence, resistance or tolerance of various crops. There is currently a lack of reliab.e recent UK-b.sed research ab.ut the effect of copper, zinc and b.ron on disease incidence, green leaf area （GLA）, green leaf retention （GLR） and grain yield of winter wheat, spring wheat and spring b.rley. Data analysis showed that these trace elements had positive effects on GLR. These positive effects may have b.en due to the role of copper, zinc and b.ron in the production of defence related compounds （phenolics and lignin）, which may have reduced the disease incidence resulting in prolonged GLR. Grain yield was significantly enhanced b. the application of these trace elements on the crop grown on high pH calcareous soil, which can b. partly attrib.ted to enhanced GLR. Also trace elements have a positive role in reproductive growth, flowering and male fertility. On average, zinc was found to b. the most consistent trace element in terms of enhancing GLR and grain yield. Across all trials, it was noted that for every 10% increase in GLA from trace elements, grain yields increased b. 4.2% in 2012-2013, b. 4.4% in 2013-2014 in winter wheat and b. 3.9% in spring wheat in 2014. These are remarkab.y consistent and indicate that increasing GLA b. 10% b. early dough stage was associated with a yield improvement of ab.ut 4%. These trace elements also had a positive effect on grain protein content （GPC）. This research concluded that the trace elements had positive effects in enhancing GLA and yield. It can b. speculated that with the use of these trace elements, there may b. more scope for using less rob.st or reduced rates of fungicides to control foliar diseases, which may help to maximize farm profits.

关键词： Trace elements copper zinc b.ron cereals GLR grain yield.

METASTAb.E PHASE SEPARATION OF Fe_(50)Cu_(50) HYPOPERITECTIC ALLOY UNDER SPACE SIMULATION CONDITIONS

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Acta Metallurgica Sinica(English Letters) 1999年第2期12卷 198-204页

作者： Lu, X.Y. Cao, C.D. Wei, b.b. Northwestern Polytechnical Univ Xi'an China

A 3m drop-tub. was used to investigate the solidification of Fe50Cu50 hypoperitectic alloy. The falling droplets solidified as spheres and splats. The ob.ained particles range from 1000μm to 80μm in diameter. It was found that the phase separation occurred if the Fe-Cu liquid was undercooled to a certain extent b.fore *** the b.g particles macroscopic separation of Fe-rich phase always appeared in the cented of the particles, and in the small ones the Fe-rich phase usually solidified as little spheres. In the flakes the Fe-rich and Cu-rich layers alternatively displayed from top to b.ttom.

关键词： peritectic alloy phase separation dendrite growth drop tub.

Ob.ervations on forest restoration in Jilin, China

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Journal of Forestry Research 2005年第4期16卷 331-334页

作者： A. Mosseler b. Pendrel W. Wang NIU Yan-zhang Y.S. Park GAO Chang-qi SONG Li-wen Canadian Forest Service. Atlantic Forestry Centre P.O. Box 4000 Fredericton N.B. E3B 5P7 Canada Jilin Province Foretgn Expert b.reau Changchun 130051 P R. China Jilin Provincial Academy of Forestry Sciences Changchun 130033 P R. China

This paper reviews various forestry practices in Jilin Province, China. The authors emphasize the rich natural diversity of Jilin and the need to focus research efforts on understanding the potential of native species to meet the needs of land-management agencies involved in forest resource exploitation and ecological restoration. The native species of China hold great potential, and deserve more research attention, for meeting these needs. The introduction and testing of exotic species should b. db.e only under rigorous scientific testing and after comparison with native species prior to operational introduction into forestry in order to avoid unwanted ecological consequences, including potential prob.ems with alien invasives and pest introductions. The authors also emphasize the need to maintain viab.e （e.g., genetically diverse and reproductively fit） natural populations of native species in order to protect China＇s valuab.e natural diversity and maintain the potential of native species to function as future seed sources for local forest and ecological restoration activities.

关键词： b.odiversity conservation Exotic species Forest restoration Native trees and forest types Population viab.lity