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Can chronic gastritis cause an increase in fecal calprotectin concentrations?

World Journal of Gastroenterology 2010年第27期16卷 3406-3410页

作者： Massimo Montalto Antonella Gallo Gianluca Ianiro Luca Santoro Ferruccio D Onofrio riccardo ricci Giovanni Cammarota Marcello Covino Monica Vastola Antonio Gasbarrini Giovanni Gasbarrini ricca rdo ricci Institute of Internal Medicine Catholic University Institute of Pathology Institute of Pa thology Catholic University00168RomeItaly

AIM:To evaluate fecal calprotectin concentrations(FCCs) in subjects with chronic gastritis and the correlation between FCCs and gastritis activity ***:FCCs were measured in 61 patients with histological diagnosis of gastritis and in 74 healthy *** grading of gastritis was performed according to the updated Sydney gastritis *** were subdivided into 2 groups according to the presence/absence of an active *** with chronic active gastritis were divided into 3 subgroups on the basis of the activity score(mild,moderate,marked).FFCs in relation to Helicobacter pylori(***) infection and proton pump inhibitor(PPI) use were also ***:FCCs in patients with chronic active gastritis were not significantly different to FCCs either in subjects with non active gastritis or in healthy *** patients with chronic active gastritis(even marked),FCCs did not significantly differ according to activity *** significant differences in FCCs were found when considering ***,as well as when considering PPI chronic ***:FCCs were not significantly increased in subjects with chronic gastritis,even in those patients with a marked neutrophil infiltration.

关键词： Chronic gastritis Fecal calprotectin Intestinal inflammation Neutrophils

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