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陕西学前师范学院学报 2017年第9期33卷 29-31页

作者：王三敏商洛学院语言文化传播学院陕西商洛726000

在搜集、调查和整理合阳地名的基础上,从合阳地名的读音和书写两个方面列举了合阳地名中的不规范现象,并剖析了其产生的原因,这对于人们读准合阳地名以及合阳地名的信息化输入都具有非常重要的意义。

关键词：合阳地名规范化

Effect of Gamma Irradiation and Selection with Fungus Filtrate(Rhizoctonia solani Kuhn)on the in Vitro Culture of Common Bean(Phaseolus vulgaris)

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American Journal of Plant Sciences 2015年第16期6卷 2672-2685页

作者： Laura Y.Solís-Ramos Marta Valdez-Melara ricardo Alvarado-Barrantes Floribeth Mora-Umana Eduardo Hernández-Jiménez natalia Barboza-Vargas Pilar Ramírez-Fonseca Plant Biotechnology & Genetic Transformation School of Biology University of Costa Rica San Pedro Costa Rica School of Statistic University of Costa Rica San Pedro Costa Rica Interagency Cooperation Agreement between the Research Center for Cellular and Molecular Biology (CIBCM) University of Costa Rica and the Phytosanitary Agency of the Ministry of Agriculture and Livestock (MAG) San José Costa Rica Research Center for Cellular and Molecular Biology (CIBCM) University of Costa Rica San Pedro Costa Rica

The present investigation was undertaken to study the effect of gamma irradiation (dose from 10 to 100 Gy) and in vitro selection with fungus filtrate as selecting agent (concentration from 20% to 100%) on the susceptibility of the common bean to Rhizoctonia solani. The best results were found with a dose of 20 Gy or a concentration of 20% of fungus filtrate applied separately. These conditions were used to evaluate the combined effect of both approaches in a second experiment. The combined effect of irradiation and then selection adversely affected growth (height and roots) and survival of the in vitro plants. It may not be necessary to combine the variation generated by irradiation with the selection technique. For future assays we propose the application of: 1) gamma radiation, thereby inducing not only mutants with pathogen resistance, but also with other agronomic traits of interest. Later in the subculture MV4 potential fungus-resistant mutants will be evaluated in the field;or 2) selection pressure using fungus filtrate during three subcultures, which may be sufficient to induce the variation necessary to obtain in vitro plants resistant to fungus.

关键词： Mutagenesis Radiosensitivity In Vitro Selection Rhizoctonia Common Bean

Thyroid nodule: Alpha Score 2.0 Classification for FnAB Selection, Multicentric Study in Latin America

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Open Journal of Radiology 2021年第4期11卷 160-174页

作者： Glenn Mena Maria Cristina Chammas Carlos Mario Gonzalez Vasquez Lylian Rocío Villagómez Marco Alfredo Muñoz Pico Patricio Alejandro Montalvo santiago Mena-Bucheli Julio Olmedo Elizabeth Quintero Pedro Henrique de Marqui Moraes Osmar Cassio Saito Hubertino Diaz Denise romero Gabriela Velalcazar Angel Ramón Sosa Fleitas Yamil Oliver Quevedo Ontaneda Victor ricardo Chara Alpha Imagen Radiología e Intervencionismo Quito Ecuador Hospital das Clínicas Faculdade de Medicina da Universidade de Sã o Paulo S&#227 o Paulo Brasil Hospital Pablo Tobón Uribe Medellin Colombia Hospital del Instituto Ecuatoriano de Seguridad Social Quito Sur Quito Ecuador Hospital san Francisco de Quito Quito Ecuador Hospital Edgardo Rebagliati Martins Lima Perú Hospital Carlos Andrade Marín Quito Ecuador Hospital de Clínicas san José de san Martín Buenos Aires Argentina Hospital Universitario de Los Andes Mérida Venezuela Hospital de la Policía Quito Ecuador Hospital Sisol Tacna Perú

Introduction: To perform a Latin-American multicentric study for the prediction of benign and malignant thyroid nodules using Alpha Score, and to compare it with ACR TIRADS® and Bethesda®. Materials and Methods: A pro... 详细信息

ng>Introduction:ng> To perform a Latin-American multicentric study for the prediction of benign and malignant thyroid nodules using Alpha Score, and to compare it with ACR TIRADS® and Bethesda®. ng>Materials and Methods:ng> A prospective multicentric study in 10 radiological hospitals and institutions of Latin America was performed and 818 thyroid nodules were analyzed by ultrasound and classified by using both ACR TIRADS® and Alpha Score;fine-needle aspiration biopsy was performed when needed and classified with Bethesda. The relationships between predictors were analyzed by using binary logistic regression, statistical significance was defined by a p-value of 0.05, with an error margin of 4% and 95% confidence intervals. ng>Results:ng> Alpha Score 2.0 establishes five types of malignant predictors: microcalcifications, irregular borders, taller-than-wide shape, predominant solid texture and hypoechogenicity;a diameter equal to or greater than 1.5 cm adds an extra point to the final score. Resulting classification divides Tns into 4 categories: benign (1.9%), low suspicion (8.7%), mild suspicion (13.6%) and high suspicion (75.7%) of malignancy probability;sensitivity of 82%, specificity of 74%, the positive predictive value of 94%, the negative predictive value of 51%, the statistical accuracy of 81%, odds ratio of 108.89 and correlation with ACR TIRADS of 0.77 and Bethesda of 0.91.ng> Conclusions: ng>Alpha Score 2.0 has superior diagnostic accuracy and performance compared to the previously published Alpha Score and is able to classify a benign Tn in a precise, safe and accurate way, avoiding unnecessary FnABs or determining the necessity of FnAB in cases of moderate to high suspicion of malignancy.

关键词： Thyroid Cancer-Clinical Radiology-Imaging Thyroid nodule Alpha Score TIRADS® Thyroid Ultrasonography

Altered Expression of Aromatase, Estrogen Receptors and Progesterone Receptors in Human Leydig Cell Hyperplasia

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Advances in Bioscience and Biotechnology 2015年第1期6卷 1-10页

作者： Candela Rocío González Pablo Ignacio Felipe Inserra Claudio Terradas Roberto Ponzio Elisa Puigdomenech Oscar Levalle Alfredo Daniel Vitullo ricardo Saúl Calandra Silvia Ines Gonzalez-Calvar Research Center of Biomedical Biotechnology Environmental and Diagnostic Studies Maimónides University Buenos Aires Argentina División Endocrinología Hospital Durand Buenos Aires Argentina Facultad de Medicina Universidad de Buenos Aires Buenos Aires Argentina Instituto Medico PREFER Calle 995 No 2348 San Martin Argentina Laboratorio de Endocrinología Molecular de la Reproducción Instituto de Biología y Medicina Experimental (CONICET) Buenos Aires Argentina Laboratorio de Endocrinología Molecular de la Reproducción Instituto de Biología y Medicina Experimental (CONICET) Facultad de Medicina Universidad de Buenos Aires Buenos Aires Argentina

Testicular function is regulated by pituitary hormones and also by paracrine and autocrine factors. A number of reports have pointed out the importance of estrogens and progesterone in male reproductive tract. Recently, we have reported in testicular biopsies from men with Sertoli Cell Only Syndrome (SCO) or Hypospermatogenesis (H) with Leydig cell hyperplasia (LCH) an increase in the expression of the TGFB1 and its receptors ALK1 and endoglin, which are involved in the proliferation of Leydig cells. The aim of the present work was to analyze the expression of aromatase, estrogen and progesterone receptors (ERs, PR) in pathological testicular biopsies with SCO or H with and without LCH. The ERs and CYP19 proteins were detected in the Leydig cells from all pathological biopsies analyzed. Biopsies with SCO or H with LCH showed an increment in the immunostaining of CYP19 and ERs in the Leydig cells respect to biopsies without LCH. The gene expression of CYP19 was increased in SCO or H biopsies with LCH respect to SCO and H biopsies without LCH. PR was localized in Leydig cells and showed a significant increment in biopsies with LCH respect from biopsies without LCH. The gene expression of both PRA and PRB was increased in biopsies with LCH respect to biopsies without LCH. In concussion, alterations in the gene expression of aromatase, ERs, and PR and the likely interactions of these systems with locally produced factors such as growth factors and cytokines, might lead to Leydig cell proliferation in testicular pathology.

关键词： Aromatase Progesterone Estrogen Leydig

南美SLR监测的2010年智利8．8级大地震产生的地面位移

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科学通报 2011年第2期56卷 142-146页

作者：尹志强韩延本 PODESTA ricardo 刘卫东 PACHECO Ana ALOnSO Ester ACTIS Eloy 黄东平赵励民王锐夏金超中国科学院国家天文台北京100012 Observatorio Astronomico Felix Aguilar San Juan University San Juan 5400 Argentina

2010年2月27日,智利发生了8.8级特大地震,该地震使震中附近的地面产生了较大位移.德国与智利合作的卫星激光测距系统SLR-7405距震中仅约130km,其观测受到地震的影响.中国科学院国家天文台与阿根廷合作的SLR-7406系统距震中约600km,利用... 详细信息

2010年2月27日,智利发生了8.8级特大地震,该地震使震中附近的地面产生了较大位移.德国与智利合作的卫星激光测距系统SLR-7405距震中仅约130km,其观测受到地震的影响.中国科学院国家天文台与阿根廷合作的SLR-7406系统距震中约600km,利用这两个SLR站的观测资料并结合全球SLR站的观测资料,在ITRF2000下解算了这两个SLR站点的地心坐标,发现两站的坐标都发生了不同程度的变化.SLR-7405站整体向西南方向发生了较大移动,在X,Y,Z方向上的位移量分别约为3.11,0.52和0.49m,SLR-7406站在3个方向上的位移量分别约为0.02,0.03和0.02m.由SLR这一独立的观测手段得到的结果可以为其他定位观测提供必要的外部检核.

关键词：地震卫星激光测距 ITRF2000 地心坐标南美洲板块运动

Exploring the adjustment to parasite pressure hypothesis: differences in uropygial gland volume and haemosporidian infection in palearctic and neotropical birds

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Current Zoology 2021年第2期67卷 147-156页

作者： Sergio MAGALLAnES Anders Pape MøLLER Charlene LUJÁn-VEGA Esteban FOnG Daniel VECCO Wendy FLORES-SAAVEDRA Luz GARCÍA-LOnGORIAA Florentino DE LOPE JoséA.IAnnACOnE Alfonso MARZAL Department of Anatomy Cellular Biology and ZoologyUniversity of ExtremaduraAvda.de Elvas S/NBadajoz ES-06006Spain Ecologie Systématique Evolution UniversitéParis-SudOrsay 91400France Key Laboratory for Biodiversity Science and Ecological Engineering of Ministry of Education College of Life SciencesBeiing Normal UniversityBeiing 100875China Pharmacology and Toxicology Graduate Group University of CaliforniaDavisDavisCA 95616USA EverGreen Institute-san Rafael Distrito de IndianaLoreto 16200Perú Centro Urku de Estudios Amazónicos Tarapoto 22202Perú Universidad nacional Agraria La Molina Lima 15024Perú Molecular Ecology and Evolution Lab Department of BiologyLund UniversityLund 22100Sweden Laboratorio de Ingenieria Ambiental Universidad Cientifica del Sur-Villa el SalvadorLima 15067Perú Laboratorio de Invertebrados Universidad Ricardo PalmaSantiago de Surco 15039Perú

Parasites are globally widespread pathogenic organisms,which impose im portant selective forces upon their ***,in accordance with the A djustm ent to parasite pressure hypothesis,it is expected that defenses among hosts vary relative to the selective pressure imposed by *** to the latitudinal gradient in diversity,species richness and abundance of parasites peak near the *** uropygial gland is an im portant defensive exocrine gland against pathogens in *** of the uropygial gland has been proposed to vary among species of birds because of divergent selection by pathogens on their ***,we should expect that bird species from the tropics should have relatively larger uropygial glands for their body size than species from higher ***,this hypothesis has not yet been ***,we analyze the size of the uropygial gland of 1719 individual birds belonging to 36 bird species from 3 neotropical(Peru)and 3 temperate areas(Spain).Relative uropygial gland volum e was 12.52%larger in bird species from the tropics than from temperate *** finding is consistent w ith the relative size of this defensive organ being driven by selective pressures imposed by *** also explored the potential role of this gland as a means of avoiding haemosporidian infection,showing that species with large uropygial glands for their body size tend to have lower mean prevalence of haemosporidian infection,regardless o f their geographical *** result provides additional support for the assum ption that secretions from the uropygial gland reduce the likelihood of becoming infected with haemosporidians.

关键词： adjustment to parasite pressure hypothesis malaria neotropical region preen oil temperate region

IMT504: A new and Potent Adjuvant for Rabies Vaccines Permitting Significant Dose Sparing

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World Journal of Vaccines 2012年第4期2卷 182-188页

作者： Alejandro D. Montaner Analia De nichilo Juan M. Rodriguez Andres Hernando-Insua Juan Fló ricardo A. Lopez Verónica Sierra Claudio Paolazzi Oscar Larghi David L. Horn Jorge Zorzopulos Fernanda Elias David Horn LLC Doylestown PA USA. Immunotech S.A. Buenos Aires Argentina Instituto de Investigaciones Biomédicas Fundación Pablo Cassará Buenos Aires Argentina Instituto san Jorge Bagó Buenos Aires Argentina Instituto san Jorge Bagó Buenos Aires Argentina. nstituto de Investigaciones Biomédicas Fundación Pablo Cassará Buenos Aires Argentina

Background: Rabies virus infection causes encephalitis, which is almost always fatal. Vaccination can be extremely effective at preventing disease but is prohibitively costly. Vaccine formulations allowing dose-sparing and fewer inoculations with faster antibody response would be extremely desirable. IMT504, an immunostimulatory non-CpG oligo-deoxynucleotide, is a highly potent vaccine adjuvant. Methods: Human and rat antibody measurements, and rat chal-lenge studies were performed. Results: In rats, highly effective immune responses with IMT504 were observed even after diluting vaccine up to 1/625. In highly lethal, live intracerebral rabies challenge studies, protection occurred even with extremely dilute vaccine plus IMT504. In humans, antibody titers developed faster and were significantly higher with IMT504-adjuvanted diluted vaccine vs non-adjuvanted vaccine (full strength or diluted). All five administered IMT504-adjuvanted diluted vaccine reached protective antibodies (≥0.5 IU/ml) after the second injection. After the third injection, individuals receiving IMT504-adjuvanted diluted vaccine reached levels approximately 10 times higher than controls (M ± SEM: 31.0 ± 10.9 vs 3.40 ± 0.99 IU/ml). Conclusions: These data suggest that IMT504 may allow fewer inoculations, highly significant dose-sparing of vaccine, rapid antibody production and protection from rabies. Extensive clinical studies are necessary to confirm if the use of IMT504 will permit significantly greater access to highly effective life-saving rabies vaccines.

关键词： IMT504 Adjuvant Rabies Vaccine Human Animal

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乙二醇溶液中高溶解度盐脱除工艺模拟

石油与天然气化工 2015年第5期44卷 77-81页

作者：梁羽贺三林林王赟邹永莉袁宗明中海石油深海开发有限公司西南石油大学

深水天然气田开发中,常用乙二醇作为水合物抑制剂。由于深水气田的采出水中含有大量的盐,常规的乙二醇再生回收系统在处理高含盐的乙二醇富液时,将产生结垢问题。这将对海上平台的生产系统带来严重影响,甚至可能导致平台停产。因此,深... 详细信息

深水天然气田开发中,常用乙二醇作为水合物抑制剂。由于深水气田的采出水中含有大量的盐,常规的乙二醇再生回收系统在处理高含盐的乙二醇富液时,将产生结垢问题。这将对海上平台的生产系统带来严重影响,甚至可能导致平台停产。因此,深水气田开发时需在乙二醇溶液再生回收的同时将其中的盐脱除。针对乙二醇再生脱盐回收系统中的高溶解度盐脱除系统部分,利用Aspen Plus建立了其核心工艺流程,并模拟和分析了乙二醇脱高溶解度盐系统中循环温度、循环流量、原料含水率等因素对系统工艺的影响规律。结果表明,针对本文的实例,在工程上采用0.15 MPa的闪蒸压力（绝压）,141~145℃的循环加热温度,循环流量是进料物流流量的60倍是可行的。

关键词：深水乙二醇再生脱盐 Aspen Plus 工艺模拟

痛性Saupe Ⅲ型二分髌骨空心钉固定与切除的比较

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中国矫形外科杂志 2023年第19期31卷 1767-1772页

作者：林三福巫海鹏王文怀陈守勃郑煜晖福建医科大学附属第二医院骨科福建泉州362000

[目的]比较空心钉固定与切除治疗痛性SaupeⅢ型二分髌骨的临床疗效。[方法]回顾性分析2008年1月-2020年1月因二分髌骨就诊本院治疗的19例患者的临床资料,根据医患沟通结果,10例行空心钉固定(固定组),9例采用关节镜行副髌骨摘除(切除组)... 详细信息

[目的]比较空心钉固定与切除治疗痛性SaupeⅢ型二分髌骨的临床疗效。[方法]回顾性分析2008年1月-2020年1月因二分髌骨就诊本院治疗的19例患者的临床资料,根据医患沟通结果,10例行空心钉固定(固定组),9例采用关节镜行副髌骨摘除(切除组)。比较两组围手术期、随访及影像资料。[结果]固定组的切口长度显著大于切除组[(3.5±0.4) cm vs(1.8±0.3) cm, P0.05)。随访时间平均(36.1±2.5)个月,随时间推移,两组VAS评分显著减少(Pngerford评分、膝伸-屈rom均显著增加(P0.05),术后12个月,固定组在VAS评分[(1.6±0.5) vs (2.9±0.8), Pngerford评分[(95.1±4.3) vs (87.5±5.4), Prom [(139.4±4.7)°vs(131.6±3.3)°, Pnsall指数均无显著变化(P>0.05),相应时间点,两组间上述影像指标的差异均无统计学意义(P>0.05)。[结论]采用空心钉固定治疗痛性二分髌骨,具有创伤小、直视下复位和固定可靠的优点,近期临床结果优于镜下切除术。

关键词：痛性二分髌骨内固定空心螺钉切除关节镜

基于FPGA并行分布式算法的FIR滤波器的实现

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黑龙江科技学院学报 2006年第4期16卷 248-250页

作者：赵金宪吴三王乃飞黑龙江科技学院电气与信息工程学院哈尔滨150027

采用FPGA实现FIR数字滤波器硬件电路的方案,基于只读存储器rom查找表的并行分布式算法,设计文件采用Verilog HDL语言进行描述。该设计方案在MAX+PlusII上进行了实验仿真和时序分析。结果表明:它克服已有软件和硬件难以达到的对信号处理... 详细信息

采用FPGA实现FIR数字滤波器硬件电路的方案,基于只读存储器rom查找表的并行分布式算法,设计文件采用Verilog HDL语言进行描述。该设计方案在MAX+PlusII上进行了实验仿真和时序分析。结果表明:它克服已有软件和硬件难以达到的对信号处理缺陷,既具有实时性,又兼顾了一定的灵活性,完全可以达到实际应用的要求。另外,对优化硬件资源利用率、提高运算速度等工程实际问题也进行了探讨。

关键词： FIR数字滤波器分布式算法 FPGA Verilog HDL