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Extreme drought triggers parallel shifts in wood anatomical and physiological traits in upper treeline of the Mediterranean Andes

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Ecological Processes 2024年第01期13卷 132-143页

作者： Luiz Santini Jr. Dylan Craven Daigard ricardo Ortega Rodriguez Manolo Trindade Quintilhan Stephanie gibson-Carpintero Cristina Aravena Torres Fidel A.Roig Ariel A.Mu?oz Alejandro Venegas-g.nzalez Hémera Centro de Observación de la Tierra Universidad Mayor gEMA Center for genomics Ecology and Environment Universidad Mayor Data Observatory Foundation ANID Technology Center Depart-ment of Forest Sciences ESALQ-University of Sao Paulo Department of Plant Biology Institute of Biology University of Campinas Instituto de geografía Universidad Nacional Autónoma de México (UNAM) Argentine Institute of Nivology Glaciology and Environmental Sciences(IANIGLA CONICET ) Institute of geography Pontificia Universidad Católica de Valparaíso Instituto de Ciencias Agroalimentarias Animales y Ambientales (ICA3) Universidad de O'Higgins

Background Treeline ecotones of Mediterranean ecoregions have been affected by the increasing intensity and severity of droughts. Even though the effect of droughts on forest dynamics has been widely documented, knowledge is relatively scarce of how extreme climate episodes affect the hydraulic structure and, therefore, the phys-iology of woody plants. The Mediterranean Andes have experienced an uninterrupted period of drought since 2010, including an extremely dry year in 2019 with approximately 80% rainfall deficit. Here, we investigated shifts in wood anatomical and physiological traits of Kageneckia angustifolia, an endemic treeline species, in response to this drought *** We evaluated the xylem plasticity of three K. angustifolia populations across their natural distribution(31–35° SL) based on anatomical(vessel structure and distribution) and physiological(intrinsic water-use efficiency) variables in the tree rings. We focused on the period 2000–2020 that corresponds to before the megadrought(2000–2007),(ii) megadrought(2008–2018) and(iii) hyperdrought(2019–2020). The variables were annualized and analyzed by linear mixed-effects *** Our results provide insights to the anatomical and physiological mechanisms underlying the resilience of treeline forests to persistent droughts in central Chile. We found that the extreme drought in 2019–2020 triggered shifts in vessel size and frequency that increased hydraulic safety. These significant shifts in vessel traits occurred in parallel with a decrease in pit aperture area and an increase in water-use efficiency, further increasing the resilience of K. angustifolia to extreme drought *** Our results revealed coordinated shifts in vessel size and frequency and water-use efficiency in response to the megadrought, thereby reducing vulnerability to hydraulic failure. The apparent resilience of K. angustifolia to extreme droughts suggests that this adaptation to drought stress may incre

关键词： Dendro-anatomy Kageneckia angustifolia Xylem vulnerability Drought Climate change

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Effect of resistance training volume on body adiposity,metabolic risk,and inflammation in postmenopausal and older females:Systematic review and meta-analysis of randomized controlled trials

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Journal of Sport and Health Science 2024年第2期13卷 145-159页

作者： Paulo ricardo Prado Nunes Pamela Castro-e-Souza Anselmo Alves de Oliveira Bruno de Freitas Camilo gislaine Cristina-Souza Lucio Marques Vieira-Souza Marcelo Augusto da Silva Carneiro Department of Body and Human Movement Minas Gerais State University(UEMG)37902-092 PassosMGBrazil University Center of Planalto de Araxa(UNIARAXA) 38180-129 AraxaMGBrazil Physical Activity Health and Ageing Research Group(GPASE)Minas Gerais State University(UEMG)37902-092 PassosMGBrazil Exercise and Nutrition Research group(gPEN) Minas Gerais State University(UEMG)37902-092 PassosMGBrazil Sport Sciences and Physical Exercise Study and Research group(gEPCEEX) Minas Gerais State University(UEMG)37902-092 PassosMGBrazil Metabolism Nutrition and Exercise LaboratoryPhysical Education and Sport CenterLondrina State University(UEL)86050-070 LondrinaPRBrazil Postgraduate Program in Physical Education Federal University of Sergipe(UFS)49107-230 Sao CristovaoSEBrazil

Purpose:This meta-analytical study aimed to explore the effects of resistance training(RT) volume on body adiposity,metabolic risk,and inflammation in postmenopausal and older ***:A systematic search was performed for randomized controlled trials in PubMed,Scopus,Web of Science,and *** controlled trials with postmenopausal and older females that compared RT effects on body adiposity,metabolic risk,and inflammation with a control group(Cg) were *** reviewers selected the studies,extracted the data,and performed the risk of bias and certainty of the evidence(grading of Recommendations,Assessment,Development,and Evaluation(gRADE)) *** body and abdominal adiposity,blood lipids,glucose,and C-reactive protein were included for meta-analysis.A random-effects model,standardized mean difference(Hedges’ g),and 95% confidence interval(95%CI) were used for ***:Twenty randomized controlled trials(overall risk of bias:some concerns;gRADE:low to very low) with overweight/obese postmenopausal and older females were *** groups were divided into low-volume RT(LVRT,~44 sets/week) and high-volume RT(HVRT,~77 sets/week).Both RT groups presented improved body adiposity,metabolic risk,and inflammation when compared to ***,HVRT demonstrated higher effect sizes than LVRT for glucose(HVRT=-1.19;95%CI:-1.63 to-0.74;LVRT=-0.78;95%CI:-1.15 to-0.41) and C-reactive protein(HVRT=-1.00;95%CI:-1.32 to-0.67;LVRT=-0.34;95%CI,-0.63 to-0.04)) when compared to ***:Compared to Cg,HVRT protocols elicit greater improvements in metabolic risk and inflammation outcomes than LVRT in overweight/obese postmenopausal and older females.

关键词： C-reactive protein Fat mass Lipid profile Menopause Strength training

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Considerations for the Conduction and Interpretation of FAIRness Evaluations

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Data Intelligence 2020年第1期2卷 285-292页

作者： ricardo de miranda Azevedo Michel Dumontier Institute of Data Science Maastricht UniversityUniversiteitssingel 60Maastricht 6229 ERThe Netherlands

The FAIR principles were received with broad acceptance in several scientific ***,there is still some degree of uncertainty on how they should be *** self-report questionnaires have been proposed to assess the implementation of the FAIR ***,the FAIRmetrics group released 14,general-purpose maturity for representing ***,these metrics were conducted as open-answer ***,these metrics have been implemented into a software that can automatically harvest metadata from metadata providers and generate a principle-specific FAIRness *** so many different approaches for FAIRness evaluations,we believe that further clarification on their limitations and advantages,as well as on their interpretation and interplay should be considered.

关键词： FAIR metrics FAIR principles FAIR data FAIRness Implementation Maturity indicators Scientific community

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Dysregulated microRNAs in type 2 diabetes and breast cancer:Potential associated molecular mechanisms

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World Journal of Diabetes 2024年第6期15卷 1187-1198页

作者： Alex Cleber Improta-Caria Filipe Ferrari João Lucas Penteado gomes Paloma Brasilio Villalta Úrsula Paula RenóSoci ricardo Stein Edilamar M Oliveira Laboratory of Biochemistry and Molecular Biology of the Exercise Physical Education and Sport SchoolUniversity of São PauloSão Paulo 05508-030Brazil graduate Program in Cardiology and Cardiovascular Sciences Federal University of Rio Grande do SulHospital de Clínicas de Porto AlegrePorto Alegre 90035003Brazil Laboratory of Metabolic Disorders(Labdime) School of Applied SciencesUniversity of Campinas-UNICAMPCampinas 13484-350Brazil Departments of Internal Medicine Molecular Pharmacology and PhysiologyCenter for Regenerative MedicineUSF Health Heart InstituteMorsani College of MedicineUniversity of South FloridaTampaFL 33602United States

Type 2 diabetes(T2D)is a multifaceted and heterogeneous syndrome associated with complications such as hypertension,coronary artery disease,and notably,breast cancer(BC).The connection between T2D and BC is established through processes that involve insulin resistance,inflammation and other *** this comprehension the specific cellular and molecular mechanisms linking T2D to BC,especially through microRNAs(miRNAs),remain *** are regulators of gene expression at the post-transcriptional level and have the function of regulating target genes by modulating various signaling pathways and biological ***,the signaling pathways and biological processes regulated by miRNAs that are associated with T2D and BC have not yet been *** review aims to identify dysregulated miRNAs in both T2D and BC,exploring potential signaling pathways and biological processes that collectively contribute to the development of BC.

关键词： Type 2 diabetes Breast cancer MicroRNAs Molecular mechanisms

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Unsuccessful tuberculosis treatment outcomes across Brazil's geographical landscape before and during the COVID-19 pandemic:are we truly advancing toward the sustainable development/end TB goal?

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Infectious Diseases of Poverty 2024年第1期13卷 105-106页

作者： Reginaldo Bazon Vaz Tavares Thais Zamboni Berra Yan Mathias Alves Marcela Antunes Paschoal Popolin Antonio Carlos Vieira Ramos Ariela Fehr Tartaro Clara Ferreira de Souza ricardo Alexandre Arcencic Department of Maternal-Infant and Public Health Nursing University of São Paulo at Ribeirão Preto College of Nursing (USP/RPCN) Ribeirão Preto São Paulo Brazil Federal University of Tocantins Palmas Campus (FUT) Palmas Brazil State University of Minas gerais Passos Campus (SUMG) Passos Brazil

Background Tuberculosis is one of the most significant infectious diseases for global public *** reallocation of healthcare resources and the restrictions imposed by the COVID-19 pandemic have hindered access to TB diag-nosis and *** in unfavorable outcomes of the disease have been observed in *** objective of this study was to analyze the spatial distribution of unfavorable TB treatment outcomes in Brazil before and during the *** An ecological study with spatial analysis was conducted with all 5569 municipalities in *** reported cases of tuberculosis between January 2010 and December 2021,as well as reported cases of COVID-19 from Febru-ary 2020 to December 2021,were *** outcomes studied encompass loss to follow-up,drug-resistant tuber-culosis,and *** getis Ord gI*technique was employed to assess spatial association,and the Kernel density estimator was used to identify areas with concentrated increases or decreases in *** Local Moran's/was used to examine the spatial association between outcomes and cOVID-19 *** study was approved by the Research Ethics Committee of Ribeirao Preto Nursing School,University of Sao *** There were 134,394 cases of loss to follow-up,10,270 cases of drug resistance,and 37,863 *** of high and low values were identified for all three outcomes,indicating significant changes in the spatial distribu-tion *** in concentrations were observed for lost to follow-up cases in the Southeast,while reductions occurred in the Northeast,South,and ***-resistant tuberculosis experienced an increase in the Southern and Southeastern regions and a decrease in the Northeast and ***-related deaths showed notable concentra-tions in the Midwest,Northeast,South,and *** was an increase in high occurrence clusters for deaths after 2020 and 2021 in the *** The pandemic has brought additional chal

关键词： Tuberculosis COVID-19 Spatial analysis Ecological studies

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Efficient metallization of magnetite concentrate by reduction with agave bagasse as a source of reducing agents

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International Journal of Minerals,Metallurgy and Materials 2021年第4期28卷 603-611页

作者： Diana Cholico-g.nzález NoemíOrtiz Lara Mario Alberto Sánchez miranda ricardo Morales Estrella Ramiro Escudero garcía Carlos ALeón Patiño CONACYT-Metallurgy and Materials Research Institute Michoacana University of San Nicolás de HidalgoMorelia CP 58030Mexico Metallurgy and Materials Research Institute Michoacana University of San Nicolás de HidalgoMorelia CP 58030Mexico

The reduction behavior and metallization degree of magnetite concentrate with agave bagasse were investigated in an inert *** effects of temperature,biomass content,and residence time on reduction experiments and metallization degree were investigated by X-ray diffraction and scanning electron *** with other types of biomass,agave bagasse had lower contents of nitrogen,sulfur,and ash.X-ray diffraction analysis showed that the metallization degree improved with increasing temperature and biomass *** metallization was achieved at 1100℃ for 30 min with 65:35 and 50:50 ratios of the magnetite concentrate to the agave *** results demonstrate that agave bagasse promotes the efficient metallization of magnetite concentrate without the external addition of a reducing ***,this biomass is a technical suitable alternative to replace fossil fuels in steelmaking.

关键词： magnetite concentrate agave bagasse biomass reduction metallization degree

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Prevalence and resistance of Helicobacter pylori in a predominantly Hispanic population

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World Journal of gastrointestinal Endoscopy 2024年第9期16卷 526-532页

作者： Alireza Tabesh ricardo Alberto Antillon Manvel Kondradzhyan Ann Zera Tan Internal Medicine Adventist Health White MemorialLos AngelesCA 90033United States Family Medicine UCLALos AngelesCA 90024United States Department of Pathology Adventist Health White MemorialLos AngelesCA 90033United States

BACKgROUND Helicobacter pylori(***)is the most common chronic bacterial infection in *** risk of acquiring *** is related to socioeconomic status and living conditions early in *** regimens must consider local antibiotic resistance *** Health White Memorial Hospital serves a predominantly indigent population in east Los Angeles with a large number of immigrants from South and Central *** regarding the prevalence and resistance of *** in this population is *** To evaluate the prevalence and resistance of *** and correlate with country of *** All gastric biopsies were obtained by a single gastroenterologist at the hospital in a consecutive manner from patients with gastritis from 2017 to 2022 and sent to various labs for *** Two hundred and sixty-six patients are born in the United States,450,171,70,and 30 patients are immigrants from Mexico,Central and South America(CSA),Asia,and other countries ***,14.65%were found to be infected with *** of infection in United States-born citizens,immigrants from Mexico,CSA,and Asia are 9.02%,18.67%,13.45%,and 11.43%respectively,with Mexican immigrants having a relative risk of 2.3889[95%confidence interval(CI):1.4789-3.8588,P=0.0004]compared to those born in United *** correlation seen between infection and length of time immigrants were in United *** risk of infection in patients with no proton pump inhibitor use within the past 30 days found to be 1.9276(95%CI:1.3562-2.7398,P=0.0003).Rates of resistance for clarithromycin and levofloxacin are 21.43%and 31.11%.CONCLUSION *** infection appears to be associated with low socioeconomic status and poor living conditions early in *** and levofloxacin based treatment regimens should be avoided as first line therapy in this region,particularly in patients of Latin American origin.

关键词： Hispanic Proton pump inhibitors gastritis Disparity Race/racial Helicobacter pylori Prevalence Resistance

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Effects of meal size and proximal-distal segmentation on gastric activity

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World Journal of gastroenterology 2010年第46期16卷 5861-5868页

作者： Madileine F Américo Marjorie V Ietsugu Fernando g Romeiro Luciana A Corá ricardo B Oliveira José ricardo A miranda Department of Physics and Biophysics IBBUNESP-Sao Paulo State University Institute of Biological Sciences and Health ICBSUFMT-University of Mato Grosso Department of Clinical Medicine FMBUNESP-Sao Paulo State University Department of Clinical Medicine FMRPUSP-University of So Paulo UNCISAL-Alagoas State University of Health Sciences

AIM:To evaluate the effects of meal size and three segmentations on intragastric distribution of the meal and gastric motility,by ***:Twelve healthy volunteers were randomly assessed,twice,by *** test meal consisted of 60 or 180 mL of yogurt labeled with 64 MBq 99m Tc-tin *** and posterior dynamic frames were simultaneously acquired for 18 min and all data were analyzed in *** proximal-distal segmentations using regions of interest were adopted for both ***:Intragastric distribution of the meal between the proximal and distal compartments was strongly influenced by the way in which the stomach was divided,showing greater proximal retention after the 180 *** important finding was that both dominant frequencies (1 and 3 cpm) were simultaneously recorded in the proximal and distal stomach;however,the power ratio of those dominant frequencies varied in agreement with the segmentation adopted and was independent of the meal ***:It was possible to simultaneously evaluate the static intragastric distribution and phasic contractility from the same recording using our scintigraphic approach.

关键词： gastric motility Phasic contractions Proximal stomach Scintigraphy Meal size

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New evidence for a role of Bisphenol A in cell *** in the human population

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BIOCELL 2022年第2期46卷 305-308页

作者： RAFAEL MORENO-gÓMEZ-TOLEDANO MARÍA IARENAS ESPERAnzA VÉlez-VÉlez ricardo J.BOSCH Universidad de Alcalá Laboratory of Renal Physiology and Experimental NephrologyDepartment of Biological Systems/Physiology28871Alcaláde HenaresSpain Universidad de Alcalá Cell Biology UnitDepartment of Biomedicine and Biotechnology28871Alcaláde HenaresSpain Jiménez Díaz Foundation Fundación Jiménez Díaz School of NursingMadrid28040Spain

Bisphenol A(BPA)is a xenoestrogen known for its implications for the endocrine systems and several other organs,including the *** renal studies have shown that BPA can induce alterations of the cytoskeleton and cell adhesion mechanisms such as a podocytopathy with proteinuria and hypertension,alterations involved in the progression of renal *** data and the fact that BPA is known to be present in the urine of almost the entire population strongly suggest the critical need to reevaluate BPA exposures considered safe.

关键词： Bisphenol A Podocyte Cytoskeleton Cell Adhesion Chronic Renal Diseases Dialysis

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Effects of western juniper(Juniperus occidentalis)control on ecosystem nitrogen stocks in central Oregon,USA

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Journal of Plant Ecology 2021年第6期14卷 1073-1089页

作者： Mohamed A.B.Abdallah ricardo Mata-g.nzález Jay S.Noller Carlos g.Ochoa Department of Animal and Rangeland Sciences Oregon State UniversityCorvallisOR 97331USA Department of Crop and Soil Science Oregon State UniversityCorvallisOR 97331USA

Aims In the Oregon of USA,the control of western juniper(Juniperus occidentalis)is an accepted rangeland management practice to restore sagebrush steppe habitats of importance to wildlife and *** effects of juniper cutting on ecosystem nitrogen,however,have not been well addressed although woody plant control has important implications for local watershed management and regional nitrogen *** We quantified ecosystem nitrogen stocks in two adjacent watersheds,comprised of a treated watershed(most juniper removed)and an untreated watershed(juniper not removed).Thirteen years after juniper removal,we measured aboveground nitrogen stocks for juniper trees,shrubs,grasses and litter in both *** also measured belowground nitrogen stocks(roots and soil)in both watersheds at two soil depths(0–25 and 25–50 cm).Important Findings Aboveground nitrogen stocks were 6.9 times greater in the untreated than in the treated watershed considering the much larger aboveground ***,root nitrogen stocks were 3.1 times greater in the treated one due to the gain of understory root biomass associated with juniper *** nitrogen stocks at both 0–25 and 25–50 cm depths were not affected by juniper ***,total ecosystem nitrogen stocks did not differ between the treated(9536 kg N ha−1)and untreated(9456 kg N ha−1)*** greatest ecosystem nitrogen accumulation(at least 95%total ecosystem nitrogen)resided belowground(soil 0–50 cm and roots)in both *** study provides evidence that the benefits of juniper removal can be attained without significantly affecting the capacity of ecosystem nitrogen storage.

关键词： aboveground nitrogen stock belowground nitrogen stock ecosystem nitrogen Juniperus occidentalis soil nitrogen woody plant encroachment

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