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Factors Associated with Mortality in Diabetic Patients with End-Stage Renal Failure Starting Emergency Hemodialysis

Open Journal of Nephrology 2024年第1期14卷 17-24页

作者： Gaël Honal Mahoungou Daniel Tony Eyeni Sinomono Farel Elilié Mawa Ongoth Éric Ngandzali-Ngabé Nestor Andzouana Raissa Laure Mayanda Aymande Okoumou-Moko Francky Ambounou Précieux Ngoma Berline Ndinga Héléna Botokoto Bothard Hardy Ibovi richard Loumingou Department of Nephrology University Hospital of Brazzaville Brazzaville Congo Faculty of Health Sciences University Marien Ngouabi Brazzaville Congo Department of Metabolic Diseases University Hospital of Brazzaville Brazzaville Congo

Background: Diabetic nephropathy is the leading cause of end-stage chronic kidney disease with poor prognosis in resource-limited settings. This study aimed to determine factors associated with mortality in patients starting dialysis treatment for end-stage chronic renal disease in an emergency context. Patients and Methods: This was a retrospective study from January 2020 to December 2022 at CHU-B. Data from 79 diabetic patients requiring emergency dialysis were compared with those of 79 non-diabetic patients with an end-stage renal disease requiring emergency dialysis. Data were collected from the Nephrology Department registry. We studied their initial clinical and biological profiles and factors related to mortality. Results: Out of 545 compiled records, 79 diabetic chronic kidney disease patients needing dialysis were included (group 1). A control group of 79 non-diabetic chronic kidney disease patients requiring emergency dialysis was also included (group 2). The average age of patients was 53.5 ± 17 years, and the duration of diabetes at dialysis initiation was 14.8 ± 4.3 years. Twenty-three percent were hypertensive. Fifty-two percent of patients experienced intra-dialytic hypotension. Death occurred in 22% of patients. Results show that age (adjusted OR 1.955;CI: 1.025 - 1.086;p-value: Conclusion: Emergency dialysis in diabetics is associated with unfavorable outcomes in terms of mortality. Despite follow-up, renal involvement remains poorly explored, emphasizing the need for physician awareness.

关键词： Diabetic Nephropathy Emergency Dialysis Republic of the Congo

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Holographic models of the scalar sector of QCD

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Chinese Physics C 2010年第9期34卷 1516-1519页

作者： Frédéric Jugeau TPCSF Institute of High Energy PhysicsChinese Academy of Sciences

We investigate the AdS/QCD duality for the two-point correlation functions of the lowest dimension scalar meson and scalar glueball operators,in the case of the Soft Wall holographic model of *** and decay constants as well as gluon condensates are compared to their QCD *** particular,the role of the boundary conditions for the bulk-to-boundary propagators is emphasized.

关键词： AdS/QCD correspondence holographic models of QCD hadron spectroscopy

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Tracing the formation and differentiation of the Earth by non-traditional stable isotopes

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Science China Earth Sciences 2019年第11期62卷 1702-1715页

作者： Fangzhen TENG Shuijiong WANG Frédéric MOYNIER Isotope Laboratory Department of Earth and Space SciencesUniversity of WashingtonSeattleWA 98195-1310USA State Key Laboratory of Geological Processes and Mineral Resources China University of GeosciencesBeijing 100083China Institut de Physique du Globe de Paris Universite de ParisParis 75238France Institut Universitaire de France Paris 75231France State Key Laboratory of Geological Processes and Mineral Resources School of Earth SciencesChina University of GeosciencesWuhan 430074China

The Earth has grown from chaotically mixed small dusts and gases to its present highly differentiated layered structure over the past 4.567 billion years. This differentiation has led to the formation of the atmosphere, hydrosphere,biosphere, crust, mantle, and core. The timing and mechanism for the formation and evolution of these different layers are still subjects of intense debate. This review brings together recent advances in using non-traditional stable isotopes to constrain major events and processes leading to the formation and differentiation of the Earth, including the Moon-forming giant impact, crustmantle interactions, evolution of life, the rise of atmospheric oxygen, extreme paleoclimate changes, and cooling rate of magmas.

关键词： Non-traditional stable isotopes Differentiation of the Earth Crust-mantle interactions Atmospheric evolution Snowball Earth Mass extinction

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On the installation of an in situ large-scale vertical SEALing (VSEAL) experiment on bentonite pellet-powder mixture

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Journal of Rock Mechanics and Geotechnical Engineering 2023年第9期15卷 2388-2401页

作者： Nadia Mokni Justo Cabrera Frédéric Deleruyelle Institut de Radioprotection et de SûretéNucléaire(IRSN) PSE-ENV/SEDRE/LETISFontenay-aux-Roses92260France

Recently,the Institute for Radiological protection and Nuclear Safety(IRSN)has launched VSEAL(Vertical SEALing)project to investigate the impact of gas migration on the long-term performance of bentonite based vertical sealing systems(VSS).The first VSEAL in situ test was emplaced in IRSN’s Underground Research Laboratory(URL)in Tournemire(France)in 2019 and was equipped with 76 wired and wireless *** test is still in progress,but the collected set of data provides already valuable information of the hydro-mechanical behavior of VSS during *** swelling core consists of a mixture of highdensity pellets and powder of MX80 bentonite in a ratio of 80/20(in dry mass).An innovative method was adopted to drill a 1-m diameter and w10-m deep shaft in order to minimize the rock perturbation at the *** a specific protocol was adopted to install the bentonite mixture together with a careful characterization of the core during construction,VSEAL 1 constitutes the unique in situ sealing test with a well-known initial structural distribution of the pellets and the *** heterogeneities occurred within the experiment during the installation process:a damaged zone developed around the shaft walls due to the interruption of the installation operations caused by COVID19 lockdown in France;a technological gap with a variable thickness between the last pellets layer and the top confining lid and a heterogeneous distribution of the bentonite powder at some layers inducing large inter pellets voids close to the bentonite-rock *** injected water volume,relative humidity,water content and swelling pressure in both radial and axial directions were *** of the results showed that the presence of installation-induced heterogeneities led to the generation of preferential flow paths that influenced the swelling pressure evolution at radial and axial directions.

关键词： Bentonite pellet-powder mixture Heterogeneities Technological gap Seals In situ test

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Uncovering recent progress in nanostructured light-emitters for information and communication technologies

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Light(Science & Applications) 2021年第9期10卷 1571-1587页

作者： Frédéric Grillot Jianan Duan Bozhang Dong Heming Huang LTCI Institut Polytechnique de ParisTélécom Paris19 place Marguerite Perey91120PalaiseauFrance Center for High Technology Materials University of New-Mexico1313 Goddard St SEAlbuquerqueNM87106USA State Key Laboratory on Tunable Laser Technology School of Electronic and Information EngineeringHarbin Institute of TechnologyShenzhen518055China

Semiconductor nanostructures with low dimensionality like quantum dots and quantum dashes are one of the best attractive and heuristic solutions for achieving high performance photonic *** one or more spatial dimensions of the nanocrystal approach the de Broglie wavelength,nanoscale size effects create a spatial quantization of carriers leading to a complete discretization of energy levels along with additional quantum phenomena like entangled-photon generation or squeezed states of light among *** article reviews our recent findings and prospects on nanostructure based light emitters where active region is made with quantum-dot and quantum-dash *** applications ranging from silicon-based integrated technologies to quantum information systems rely on the utilization of such laser ***,we link the material and fundamental properties with the device *** this purpose,spectral linewidth,polarization anisotropy,optical nonlinearities as well as microwave,dynamic and nonlinear properties are closely *** paper focuses on photonic devices grown on native substrates(InP and GaAs)as well as those heterogeneously and epitaxially grown on silicon *** research pipelines the most exciting recent innovation developed around light emitters using nanostructures as gain media and highlights the importance of nanotechnologies on industry and society especially for shaping the future information and communication society.

关键词： emitter communication polarization

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Vineyards,but not cities,are associated with lower presence of a generalist bird,the Common Blackbird(Turdus merula),in Western France

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Avian Research 2021年第1期12卷 17-27页

作者： Bertille Mohring Francois Brischoux Frédéric Angelier Centre d’Etudes Biologiques de Chizé UMR 7372CNRS–La Rochelle Université79360 Villiers en BoisFrance Environmental and Marine Biology Abo Akademi University20520 TurkuFinland.

Background:Land-use change is one of the main drivers of the global erosion of *** that context,it is crucial to understand how landscape characteristics drive the presence of rare endangered ***,it is also important to study common species in multiple habitats,because they represent a large proportion of biodiversity and are essential to maintain ecological ***,some habitats,as farmlands with permanent crops(***),have been overlooked in the ***:In this study,we investigated the distribution of a widespread and common bird species,the Common Blackbird(Turdus merula),within and between the three main habitats of our study area(rural Western France).We specifically focused on(1)woodlands,(2)farmlands with a high vineyard coverage,and(3)moderately urbanized ***,we aimed to assess the beneficial and detrimental effects of these habitats and their fine-scale composition on the presence of a common bird species,relying on a survey by point counts(nearly 100 locations).We studied the effects of habitats and gradients of fine-scale habitat composition on blackbird presence using logistic regression ***:Blackbirds were present in all studied ***,their presence varied between habitats,being lower in vineyards than in woodlands and *** woodlands and cities,fine-scale analyses did not reveal any component driving the species'***,we found that shrub and tree vegetation cover had a significant positive effect on blackbird presence in ***:Our results are in agreement with the definition of a generalist ***,species distribution varied between *** high presence of blackbirds in urban areas suggests that medium-sized cities,despite their artificialization,do not constrain the settlement of this former forest specialist and that green spaces may allow blackbirds to thrive in medium-sized *** the contrar

关键词： Agriculture Biodiversity Birds Forest Turdus merula Urbanization Vineyards

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Impact of zinc and arginine on antioxidant status of weanling piglets raised under commercial conditions

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Animal Nutrition 2019年第3期5卷 227-233页

作者： Nadia Bergeron Frédéric Guay Departement des Sciences Animales Université Laval

The effects of dietary zinc and L-arginine supplements on the weight gain,feed efficiency,antioxidant capacity and oxidative status of weanling piglets raised under commercial conditions were examined.A total of 288 piglets aged 21 d were fed for 15 d a diet supplemented or not with 2,500 mg/kg of zinc(provided as zinc oxide)and 1% L-arginine *** 4 treatments were distributed in a randomized complete block design with 6 initial body weight categories(12 animals per pen).Access to feed and water was ad *** were analyzed as a 2 x 2 factorial experiment using the SAS MIXED procedure,with zinc and arginine as the main independent *** collection day(d 8 and 15,samples were collected from the same 2 piglets in each pen before the morning feeding)was included as a third *** zinc supplement increased the average daily gain(ADG)from d 0 to 7.d 8 to 15 and d 0 to 15(0.289 vs.0.217 kg/d).average daily feed intake(ADFR)from d 8 to 15 and d 0 to 15(0.338 vs.0.279 kg/d)and the gain to feed(G:F)ratio from d 0 to 7 and d 0 to 15(0.86 vs.0.77)(P<0.001).Both supplements significantly decreased the malondialdehyde concentration(zinc:4.37 vs.3.91 μmol/L,P= 0.005;arginine:4.38 vs.3.89 μmol/L,P = 0.002).Total antioxidant capacity and reduced glutathione(GSH)increased from d 8 to 15(0.953 vs.1.391 μmol/L,2.22 vs.3.37 μmol/L,P<0.05)regardless of dietary *** and oxidized GSH concentrations on d 8 were higher in response to the combined supplements(zinc x arginine interaction.P<0.05).Piglets fed either Zn-supplemented diet had a lower haptoglobin serum concentration(509 vs.1.417 mg/L;P<0.001).In conclusion,the zinc supplement improved piglet growth performance(ADG and ADFI)and oxidative status(based on malondialdehyde concentration).The arginine supplement had a limited effect on growth performance and oxidative status under these conditions.

关键词： Zinc Arginine Weanling piglets Antioxidant status Growth performance

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Transmission ecology of rodent-borne diseases:New frontiers

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Integrative Zoology 2015年第5期10卷 424-435页

作者： Frédéric BORDES Kim BLASDELL Serge MORAND Centre National de la Recherche Scientifique(CNRS)-Centre de coopération Internationale en Recherche Agronomique pour le Développement(CIRAD)Animal et Gestion Intégrée des Risques Centre d’Infectiologie Christophe Mérieux du LaosVientianeLao PDR Commonwealth Scientific and Industrial Research Organisation Livestock IndustriesAustralian Animal Health LaboratoryGeelongVictoriaAustralia

Rodents are recognized reservoir hosts for many human zoonotic *** current trends resulting from anthropocene defaunation suggest that in the future they,along with other small mammals,are likely to become the dominant mammals in almost all human-modified *** intricate studies on bat-borne emerging diseases have highlighted that many gaps exist in our understanding of the zoonotic transmission of rodent-borne *** has emphasized the need for scientists interested in rodent-borne diseases to integrate rodent ecology into their analysis of rodent-borne pathogen transmission in order to identify in more detail the mechanisms of spillover and chains of *** studies are required to better understand the true impact of rodent abundance and the importance of pathogen sharing and circulation in multi-host–multi-pathogen *** also need to explore in more depth the roles of generalist and abundant species as the potential links between pathogen-sharing,co-infections and disease transmission.

关键词： biodiversity dilution effect multi-infection rodent-borne diseases transmission ecology

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RNA silencing movement in plants

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Journal of Integrative Plant Biology 2016年第4期58卷 328-342页

作者： Glykeria Mermigka Frdric Verret Kriton Kalantidis Department of Biology University of Crete Institute of Molecular Biology and Biotechnology Foundation for Research and Technology

Multicellular organisms, like higher plants, need to coordinate their growth and development and to cope with environmental cues. To achieve this, various signal molecules are transported between neighboring cells and distant organs to control the fate of the recipient cells and organs. RNA silencing produces cell non-autonomous signal molecules that can move over short or long distances leading to the sequence specific silencing of a target gene in a well defined area of cells or throughout the entire plant,respectively. The nature of these signal molecules, the route of silencing spread, and the genes involved in their production, movement and reception are discussed in this review. Additionally, a short section on features of silencing spread in animal models is presented at the end of this review.

关键词： Cell non-autonomous post-transcriptional gene silencing RNA interference short range silencing spread systemic silencing plant RNA silencing transcriptional gene silencing

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A dynamic logic for verification of synchronous models based on theorem proving

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Frontiers of Computer Science 2022年第4期16卷 235-237页

作者： Yuanrui Zhang Frédéric Mallet Zhiming Liu School of Mathematics and Statistics Southwest UniversityChongqing400715China University Cote d’Azur CNRSInriaI3SNice06103France Center for Intelligent and Embedded Software Northwest Polytechnical UniversityXi’an710129China

1Introduction Synchronous models,a modelling paradigm proposed along with the development of synchronous programming languages[1]in,the 198os,are well-adapted for modelling and specifying reactive *** of systems that consecutively interact with their environment at a particular environment-determined *** a synchronous model,system behaviours are interpreted as a sequence of reactions.

关键词： theorem adapted programming

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