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Wronskian Form of N-Solitonic Solution for a Variable-Coefficient Korteweg-de Vries Equation with Nonuniformities

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Communications in Theoretical Physics 2008年第11期50卷 1185-1188页

作者： CAI Ke-Jie TIAN Bo ZHANG Cheng ZHANG huan MENG xiang-hua lu Xing GENG Tao liu Wen-Jun School of Science P.O. Box 122 Beijing University of Posts and Telecommunications Beijing 100876 China State Key Laboratory of Software Development Environment Beijing University of Aeronautics and Astronautics Beijing 100083 China Key Laboratory of Optical Communication and Lightwave Technologies Ministry of Education Beijing University of Posts and Telecommunications Beijing 100876 China

By the symbolic computation and Hirota method, the bilinear form and an auto-Backlund transformation for a variable-coemcient Korteweg-de Vries equation with nonuniformities are given. Then, the N-solitonic solution in terms of Wronskian form is obtained and verified. In addition, it is shown that the （N - 1）- and N-solitonic solutions satisfy the auto-Backlund transformation through the Wronskian technique.

关键词： variable-coefficient KdV equation bilinear auto-Bocklund transformation N-solitonic solution Wronskian determinant

Two New Steroidal Saponins from Ypsilandra thibetica

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Natural Products and Bioprospecting 2014年第6期4卷 315-318页

作者： Yong-Ai Si huan Yan Wei Ni Zhen-hua liu Ting-xiang lu Chang-xiang Cheng Hai-Yang liu State Key Laboratory of Phytochemistry and Plant Resources in West China Kunming Institute of BotanyChinese Academy of SciencesKunming 650201China University of Chinese Academy of Sciences Beijing 100049China

Two new monosaccharide steroidal saponins,named ypsilandroside S(1)and ypsilandroside T(2),have been isolated from the whole plants of Ypsilandra *** structures were elucidated as heloniogenin 3-O-b-D-apiofuranoside(1)and pregna 5,16-dien-3b,12a-diol-20-one-3-O-b-D-apiofuranoside(2)by spectroscopic techniques(1D and 2D NMR,MS).Compounds 1 and 2 were tested for their inhibitory effects on lipopolysaccharide-induced nitric oxide production in RAW 264.7 cells.

关键词： Ypsilandra thibetica Liliaceae Ypsilandroside S Ypsilandroside T

Synthesis of amorphous Pd-based nanocatalysts for efficient alcoholysis of styrene oxide and electrochemical hydrogen evolution

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Nano Research 2023年第4期16卷 4650-4655页

作者： Yiyao Ge Jingjie Ge Biao huang Xixi Wang Guigao liu xiang-huan Shan lu Ma Bo Chen Guanghua liu Songmo Du An Zhang Hongfei Cheng Qingbo Wa Shiyao lu lujiang Li Qinbai Yun Kuo Yuan Qinxin luo Zhichuan J.Xu Yonghua Du hua Zhang Department of Chemistry City University of Hong KongHong KongChina Hong Kong Branch of National Precious Metals Material Engineering Research Center(NPMM) City University of Hong KongHong KongChina Shenzhen Research Institute City University of Hong KongShenzhen 518057China Department of Chemical and Biological Engineering HKUST Jockey Club Institute for Advanced Study&Energy InstituteThe Hong Kong University of Science and TechnologyHong KongChina School of Materials Science and Engineering Nanyang Technological UniversitySingapore 639798Singapore Department of Chemistry University of Science and Technology of ChinaHefei 230026China National Synchrotron Light Source II Brookhaven National LaboratoryUptonNew York 11973USA State Key Laboratory of New Ceramics&Fine Processing School of Materials Science and EngineeringTsinghua UniversityBeijing 100084China

Amorphous nanomaterials with long-range disordered structures could possess distinct properties and promising applications,especially in catalysis,as compared with their conventional crystalline *** is imperative to achieve the controlled preparation of amorphous noble metal-based nanomaterials for the exploration of their phase-dependent ***,we report a facile wet-chemical reduction strategy to synthesize various amorphous multimetallic Pd-based nanomaterials,including PdRu,PdRh,and *** phase-dependent catalytic performances of distinct Pd-based nanomaterials towards diverse catalytic applications have been ***,the usage of PdRu nanocatalysts with amorphous and crystalline face-centered cubic(fcc)phases can efficiently switch the ring-opening route of styrene oxide to obtain different products with high selectivity through alcoholysis reaction and hydrogenation reaction,***,when used as an electrocatalyst for hydrogen evolution reaction(HER),the synthesized amorphous PdRh nanocatalyst exhibits low overpotential and high turnover frequency values,outperforming its crystalline fcc counterpart and most of the reported Pd-based HER electrocatalysts.

关键词： amorphous nanomaterials Pd-based nanocatalysts phase engineering of nanomaterials ring-opening reaction of styrene oxide electrocatalytic hydrogen evolution

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瞬时淬火工艺下低碳钢的组织演变规律

东北大学学报（自然科学版） 2015年第11期36卷 1567-1571页

作者：卢日环刘相华闫述刘立忠东北大学材料与冶金学院辽宁沈阳110819

为了探究瞬时淬火工艺下低碳钢组织的演变规律,在热模拟机上对Q195和CR340试样进行了瞬时淬火处理.结果表明,瞬时淬火工艺初期得到马氏体+贝氏体+铁素体+未溶渗碳体的复杂混合组织;保温足够时间后,未溶渗碳体逐渐溶解使奥氏体平均碳浓... 详细信息

为了探究瞬时淬火工艺下低碳钢组织的演变规律,在热模拟机上对Q195和CR340试样进行了瞬时淬火处理.结果表明,瞬时淬火工艺初期得到马氏体+贝氏体+铁素体+未溶渗碳体的复杂混合组织;保温足够时间后,未溶渗碳体逐渐溶解使奥氏体平均碳浓度升高,奥氏体晶粒内碳浓度梯度减小,从而增加组织中马氏体相对量,最终得到全部板条马氏体组织.瞬时淬火工艺与传统淬火工艺相比可明显细化试验钢晶粒尺寸,提高升温速率对试验钢晶粒细化作用更明显.

关键词：瞬时淬火低碳钢组织演变奥氏体碳浓度

Efficacy and Safety of Niaoduqing Particles for Delaying Moderate-to-severe Renal Dysfunction： A Randomized, Double-blind, Placebo-controlled, Multicenter Clinical Study

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Chinese Medical Journal 2017年第20期130卷 2402-2409页

作者： Ying Zheng Guang-Yan Cai Li-Qun He Hong-Li Lin Xiao-Hong Cheng Nian-Song Wang Gui-hua Jian Xu-Sheng liu Yu-Ning liu Zhao-Hui Ni Jing-Ai Fang Han-lu Ding Wang Guo Ya-Ni He Li-hua Wang Ya-Ping Wang Hong-Tao Yang Zhi-Ming Ye Ren-huan YU Li-Juan Zhao Wen-hua Zhou Wen-Ge Li Hui-Juan Mao Yong-Li Zhan Zhao Hu Chen Yao ri-Bao Wei xiang-Mei Chen Department of Nephrology Chinese People's Liberation Army General Hospital Chinese People's Liberation Army Institute of Nephrology State Key Laboratory of Kidney Diseases (2011DAVO0088) National Clinical Research Center for Kidney Diseases Beijing 100853 China Department of Nephrology Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine Shanghai 200021 China Department of Nephrology First Affiliated Hospital of Dalian Medical University Dalian Liaoning 116011 China Department of Nephrology Shaanxi Traditional Chinese Medicine Hospital Xi'an Shaanxi 710003 China Department of Nephrology and Rheumatology Affiliated Sixth People's Hospital Shanghai Jiao Tong University Shanghai 200233 China Department of Nephrology Guangdong Provincial Hospital of Chinese Medicine Guangzhou Guangdong 510120 China Department of Nephrology Dongzhimen Hospital The First Affiliated Hospital of Beijing University of Chinese Medicine Beijing 100700 China Department of Nephrology Renji Hospital Shanghai Jiao Tong University Shanghai 200127 China Department of Nephrology First Affiliated Hospital of Shanxi Medical University Taiyuan Shanxi 030001 China Department of Nephrology University of Electronic Science and Technology Sichuan Academy of Sciences and Sichuan Provincial People's Hospital Chengdu Sichuan 610072 China Department of Nephrology Beijing Friendship Hospital Capital Medical University Beijing 100050 China Department of Nephrology Daping Hospital Third Military Medical University Chongqing 400042 China Department of Nephrology Second Affiliated Hospital of Shanxi Medical University Taiyuan Shanxi 030001 China Department of Nephrology Army General Hospital Beijing 100700 China Department of Nephrology First Teaching Hospital of Tianjin University of Traditional Chinese Medicine Tiaojin 300192 China Department of Nephrology Guangdong General Hospital Guangdong Academy of Medical Sciences Guangzhou Guangdong 510030 China Department o

Background： Chronic kidney disease （CKD） with moderate-to-severe renal dysfunction usually exhibits an irreversible course, and available treatments for delaying the progression to end-stage renal disease are limited. This study aimed to assess the efficacy and safety of the traditional Chinese medicine, Niaoduqing particles, for delaying renal dysfunction in patients with stage 3b-4 ***： The present study was a prospective, randomized, double-blind, placebo-controlled, naulticentcr clinical trial. Frorn May 2013 to December 2013,300 CKD patients with an estimated glomerular filtration rate （eGFR） between 20 and 45 ml ＂rain ~＂ 1.73 m 2, aged 18-70 years were recruited from 22 hospitals in 11 Chinese provinces. Patients were randomized in a 1：1 ratio to either a test group, which was administered Niaoduqing particles 5 g thrice daily and 10 g before bedtime for 24 weeks, or a control group, which was administered a placebo using the same methods. The primary endpoints were changes in baseline serum creatinine （Scr） and eGFR after completion of treatment. The primary endpoints were analyzed using Student＇s t-test or Wilcoxon＇s rank-sum test. The present study reported results based on an intention-to-treat （ITT） analysis. Results： A total of 292 participants underwent the ITT analysis. At 24 weeks, the median （interquartile range） change in Scr was 1.1 （-13.0-24.1） and 11.7 （-2.6-42.9） p, mol/L for the test and control groups, respectively （Z = 2.642, P = 0.008）, and the median change in eGFR was -0.2 （-4.3-2.7） and -2.2 （-5.7-0.8） ***-1·1.73 m-2, respectively （Z = -2.408, P = 0.016）. There were no significant differences in adverse events between the groups. Conclusions： Niaoduqing particles safely and effectively delayed CKD progression in patients with stage 3b-4 CKD. This traditional Chinese medicine may be a promising alternative medication for patients with moderate-to-severe renal dysfunction.

关键词： Chronic Kidney Disease Moderate-to-severe Renal Dysfunction Niaoduqing Particles Randomized Controlled Trial Traditional Chinese Medicine

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高岭土微粒固载成核微生物固化粗砂强度

岩土工程学报 2021年第2期43卷 290-299页

作者：马国梁何想路桦铭吴焕然刘汉龙楚剑肖杨重庆大学土木工程学院重庆400045 重庆大学山地城镇建设与新技术教育部重点实验室重庆400045 库区环境地质灾害防治国家地方联合工程研究中心(重庆) 重庆400045 南洋理工大学土木与环境工程学院新加坡639789

提出一种基于微粒固载成核的微生物固化技术(MICPMPIN),用于改善微生物诱导碳酸钙沉淀(MICP)固化粗砂的力学特性,即在灌浆前给菌液中加入一定量的高岭土形成微生物固载胶体,然后将微生物固载胶体与反应液混合形成MICP浆体(MICPCS),利用... 详细信息

提出一种基于微粒固载成核的微生物固化技术(MICPMPIN),用于改善微生物诱导碳酸钙沉淀(MICP)固化粗砂的力学特性,即在灌浆前给菌液中加入一定量的高岭土形成微生物固载胶体,然后将微生物固载胶体与反应液混合形成MICP浆体(MICPCS),利用自重渗流法加固粗砂。试验结果表明新型MICPMPIN固化粗砂的强度比传统MICP固化粗砂的强度高。其他条件相同时,MICPMPIN固化粗砂的强度随高岭土掺量的增加而增加,随微生物固载胶体含量的增大而增加,且每间隔1次灌入MICPCS时固化粗砂的强度较高。高岭土本身提供的胶结强度不能使砂柱成型,可忽略不计,其作用主要是辅助成核,增加有效碳酸钙沉淀量,并减小试样孔隙比从而增强固化粗砂的效果。MICPMPIN固化粗砂的湿强度也大于传统MICP固化粗砂的湿强度,且高岭土的掺入显著增强了固化粗砂的抗软化能力。

关键词： MICP 粗砂高岭土 MICP浆体微粒固载成核

The Optimum Sowing Time for Plastic-film Corn and the Application of Two Related Theories

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Agricultural Sciences in China 2002年第5期1卷 508-515页

作者： WU Rui-xiang, liu Rong-quan, lu Cui-ling, lu Yong-lai, LI hua, ZHANG Li, lu Xiu-zhi, YU Shu-ping, WU Xiu-yan and WANG Xin-huan(Ningcheng Agro-technique Extension Centre , Inner Mongolia Autonomous Region , Tianyi 024200 , P. R. China Ningcheng Seed Company , Inner Mongolia Autonomous Region , Tianyi 024200 , P. R . China) Ningcheng Agro-technique Extension Centre Inner Mongolia Autonomous Region Tianyi 024200 P. R. China Ningcheng Seed Company Inner Mongolia Autonomous Region Tianyi 024200 P. R. China

There are two main theories, the 'temperature-raising' theory and the 'precipitation-based regulation' theory, which guide the optimum sowing time of the plastic-film corn. The former was applied in the humid or semi-humid ecotope and on irrigated or half-shaded land in the arid and semi-arid ecotopes, while the latter was suitable for the dry-farming land in the semi-arid ecotope. The results of experiments and investigations for many years showed that the corn output was increased by 69.2% when the former theory was applied to guide the optimum sowing time for plastic-film corn in the semi-humid ecotope, and by 60. 0% when the latter theory was applied in the semi-arid ecotope. In the semi-arid ecotope, however, the output was increased only by 15.7% when the former theory was applied, and even dropped by 14.4% when the latter theory was applied.

关键词： Plastic-film corn Division of climatic ecology Optimum sowing time 'Temperature-raising' theory 'Precipitation-based regulation' theory

GCH1 variants contribute to the risk and earlier age-at-onset of Parkinson's disease:a two-cohort case-control study

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Translational Neurodegeneration 2020年第3期9卷 409-420页

作者： Hong-xu Pan Yu-wen Zhao Jun-pu Mei Zheng-huan Fang Yige Wang Xun Zhou Yang-jie Zhou Rui Zhang Kai-lin Zhang Li Jiang Qian Zeng Yan He Zheng Wang Zhen-hua liu Qian Xu Qi-ying Sun Yang Yang Ya-cen Hu Ya-se Chen Juan Du Li-fang Lei Hai-nan Zhang Chun-yu Wang Xin-xiang Yan lu Shen Hong Jiang Jie-qiong Tan Jin-chen Li Bei-sha Tang Ji-feng Guo Department of Neurology Xiangya HospitalCentral South UniversityChangsha 410008China National Clinical Research Center for Geriatric Disorders Xiangya HospitalCentral South UniversityChangsha 410008China Centre for Medical Genetics and Hunan Key Laboratory of Medical Genetics School of Life SciencesCentral South UniversityChangsha 410008China Department of Geriatrics Xiangya HospitalCentral South UniversityChangsha 410008China Department of Neurology The Third Xiangya HospitalCentral South UniversityChangsha 410013China Department of Neurology The Second Xiangya HospitalCentral South UniversityChangsha 410011China Key Laboratory of Hunan Province in Neurodegenerative Disorders Central South UniversityChangsha 410008China

Background:Common and rare variants of guanosine triphosphate cyclohydrolase 1(GCH1)gene may play important roles in Parkinson's disease(PD).However,there is a lack of comprehensive analysis of GCH1 genotypes,especially in non-coding *** aim of this study was to explore the genetic characteristics of GCH1,including rare and common variants in coding and non-coding regions,in a large population of PD patients in Chinese mainland,as well as the phenotypic characteristics of GCH1 variant ***:In the first cohort of this case-control study,we performed whole-exome sequencing in 1555 patients with early-onset or familial PD and 2234 healthy controls;then in the second cohort,whole-genome sequencing was performed in sporadic late-onset PD samples(1962 patients),as well as 1279 *** at target GCH1 regions were extracted,and then genetic and detailed phenotypic data were analyzed using regression models and the sequence kernel association *** also performed a meta-analysis to correlate deleterious GCH1 variants with age at onset(AAO)in PD ***:For coding variants,we identified a significant burden of GCH1 deleterious variants in early-onset or familial PD cases compared to controls(1.2%VS 0.1%,Priants in GCH1 non-coding regions,rs12323905(P=0.001,odds ratio=1.19,95%CI 1.07-1.32)was significantly associated with PD,and variant sets in untranslated regions and intron regions,GCH1 brain-specific expression quantitative trait loci,and two possible promoter/enhancer(GH14J054857 and GH14J054880)were suggestively associated with *** phenotype correlation analysis revealed that the carriers of GCH1 deleterious variants manifested younger AAO(Prious variant carriers(P=0.0009).Conclusions:The results

关键词： Parkinson's disease Age at onset GCH1 Deleterious variants Non-coding variants

Effects of Niaoduqing Particles(尿毒清颗粒)on Delaying Progression of Renal Dysfunction:A Post-trial,Open-Label,Follow-up Study

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Chinese Journal of Integrative Medicine 2019年第3期25卷 168-174页

作者： ZHENG Ying WANG Nian-song liu Yu-ning HE Li-qun JIAN Gui-hua liu Xu-sheng NI Zhao-hui CHENG Xiao-hong LIN Hong-li ZHOU Wen-hua WANG Ya-ping FANG Jing-ai HE Ya-ni YANG Hong-tao ZHAO Li-juan DING Han-lu WANG Li-hua YU Ren-huan LI Wen-ge YE Zhi-ming GUO Wang ZHAN Yong-li MAO Hui-juan HU Zhao YAO Chen CAI Guang-yan CHEN xiang-mei Department of Nephrology Chinese People's Liberation Army General Hospital Chinese People's Liberation Army Institute of Nephrology State Key Laboratory of Kidney Diseases (2011DAV00088) National Clinical Research Center for Kidney Diseases Department of Nephrology and Rheumatology Affiliated Sixth People's Hospital Shanghai Jiaotong University Department of Nephrology Dongzhimen Hospital The First Affiliated Hospital of Beijing University of Chinese Medicine Department of Nephrology Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine Department of Nephrology Guangdong Provincial Hospital of Chinese Medicine Department of Nephrology Renji Hospital Shanghai Jiaotong University Department of Nephrology Shaanxi Traditional Chinese Medicine Hospital Department of Nephrology First Affiliated Hospital of Dalian Medical University Department of Nephrology Second Hospital of Jilin University Department of Nephrology Army General Hospital Department of Nephrology First Affiliated Hospital of Shanxi Medical University Department of Nephrology Daping Hospital Army Medical University Department of Nephrology First Teaching Hospital of Tianjin University of Traditional Chinese Medicine Department of Nephrology Xijing Hospital Air Force Medical University Department of Nephrology University of Electronic Science and Technology Sichuan Academy of Sciences and Sichuan Provincial People's Hospital Department of Nephrology Second Affiliated Hospital of Shanxi Medical University Department of Nephrology Xiyuan Hospital China Academy of Chinese Medical Sciences Department of Nephrology China-Japan Friendship Hospital Department of Nephrology Guangdong General Hospital Guangdong Academy of Medical Sciences Department of Nephrology Beijing Friendship Hospital Capital Medical University Department of Nephrology Guang'anmen Hospital of China Academy of Traditional Chinese Medical Sciences Department of Nephrology Jiangsu Province Hospital First Affiliated Hospital of Nan

Objective: To follow up the participants of the randomized clinical trial "Efficacy and Safety of Niaoduqing Particles(尿毒清颗粒) for Delaying Moderate-to-Severe Renal Dysfunction", and assess the long-term effects of Niaoduqing Particles on delaying the progression of renal dysfunction. Methods: Participants, who had previously been randomly assigned to receive Niaoduqing Particles or placebo for 24 weeks(146 cases in each group), were invited to follow-up and all were administered Niaoduqing Particles 5 g thrice daily and 10 g before bedtime for 24 weeks. The primary endpoints were changes in baseline serum creatinine(Scr) and estimated glomerular filtration rate(e GFR) after completion of the open-label treatment period. Results: After the double-blind period, the median(interquartile range) changes in Scr were 1.1(–13.0–24.1) and 11.7(–2.6–42.9) μmol/L for the Niaoduqing Particle and placebo groups, respectively(P=0.008), and the median changes in e GFRs were –0.2(–4.3–2.7) and –2.21(–5.7–0.8) mL·min^(-1)·1.73 m^(-2), respectively(P=0.016). There were significant differences in the double-blind period changes in renal function between groups. After the open-label period, the median changes in Scr were 9.0(–10.0–41.9) and 17.5(–6.0–50.0) μmol/L for the Niaoduqing Particle and placebo groups according to baseline grouping, respectively(P=0.214), and the median changes in eGFRs were –2.3(–6.4–1.9) and –3.7(–7.5–1.1) mL·min^(-1)·1.73 m^(-2), respectively(P=0.134). There were no statistical differences in the open-label period changes in renal function between groups. The eGFR reduction of participants who accepted Niaoduqing Particle treatment for 48 weeks was projected to 2.5 m L·min^(-1)·1.73 m(-2) per year. Conclusions: Niaoduqing Particles appear to have long-term efficacy for patients with moderate-to-severe renal dysfunction. Although there was no statistical difference, the early use of Niaoduqing Paticles seems to ameliorate the worsening of renal function.

关键词： chronic kidney disease moderate-to-severe renal dysfunction Niaoduqing Particles post-trial follow-up Chinese medicine