检索结果-南通市图书馆

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

PET FISH

空中英语教室（初级版．大家说英语） 2024年第9期 7-8,50页

作者： rhonda Telfer 不详

Do you want some quiet,colorful pets?Try fish!Get a tank and add clean water to *** you have a home for fish!Goldfish are orange,red or *** are small and *** can be many *** fish have wide and beautiful *** can also a... 详细信息

关键词： tank orange Clean

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

保持清醒和安然入睡的小贴士

空中英语教室（初级版．大家说英语） 2024年第10期 34-36,54,55,56页

作者： rhonda Telfer 不详

你白天会容易犯困吗?如果会的话,试试这几招。时不时从座位上站起来休息一下,每个小时都站起来伸展一下,那会有助于你保持清醒。你可以喝咖啡或茶,冰水也有帮助。吃点儿零食,但不要吃糖分太高的,那对你没有好处。如果可以,去户外散一会... 详细信息

你白天会容易犯困吗?如果会的话,试试这几招。时不时从座位上站起来休息一下,每个小时都站起来伸展一下,那会有助于你保持清醒。你可以喝咖啡或茶,冰水也有帮助。吃点儿零食,但不要吃糖分太高的,那对你没有好处。如果可以,去户外散一会儿步,阳光和新鲜空气都会让你清醒,运动也可以让你精力充沛。

关键词：安然入睡小贴士精力充沛清醒

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

新朋友风波

空中英语教室（初级版．大家说英语） 2024年第8期 14-15,51页

作者： rhonda Telfer 不详

找找看第三个星期Ben带了什么来?每个星期五,Ryan都会举办“游戏之夜”活动。他会订比萨,由大家一起分摊费用。一个星期五,Ryan的新朋友Ben参加了活动,大家都很喜欢他讲的笑话。

关键词：分摊费用星期五朋友

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

用好问题开启对话

空中英语教室（初级版．大家说英语） 2024年第8期 39-41,55,56页

作者： rhonda Telfer 不详

你能开启一段优质对话吗?那不难,你只需要问一些好问题。对方可以只用“是”或“不是”回答你吗?如果可以,那么那个问题就不够好,这会中断你的对话。你可以问:“你有什么爱好?”或是问:“你空闲的时候会做什么?”或许对方手里拿着某个东... 详细信息

你能开启一段优质对话吗?那不难,你只需要问一些好问题。对方可以只用“是”或“不是”回答你吗?如果可以,那么那个问题就不够好,这会中断你的对话。你可以问:“你有什么爱好?”或是问:“你空闲的时候会做什么?”或许对方手里拿着某个东西,可能是一本书。那你可以问:“那本书讲了什么?”好问题可以建立长久的友谊!

关键词：对话问题开启

Anal cancer screening in women with a history of human papillomavirusrelated lower genital tract cancers:a pilot study

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Gynecology and Obstetrics Clinical Medicine 2024年第2期4卷 88-93页

作者： Isobel Mary Poynten Fengyi Jin rhonda Farrell Trevor Tejada-Berges Carmella Law Richard Hillman Jennifer Roberts Andrew Grulich The Kirby Institute University of New South WalesSydneyNew South WalesAustralia Chris O'Brien Lifehouse SydneyNew South WalesAustralia Prince of Wales Private Hospital RandwickNew South WalesAustralia Dysplasia and Anal Cancer Services St Vincent's Hospital SydneyDarlinghurstNewSouthWalesAustralia Douglass Hanly Moir Pathology SydneyNew South WalesAustralia

Objectives Women diagnosed with a history of lower genital tract cancer(LGTC)and precancer are at increased risk of anal *** for anal cancer in a manner analogous to cervical cancer may detect precursor anal high-grade squamous intraepithelial lesions(HSILs)and prevent progression to *** In a pilot study of anal cancer screening,women with previous LGTC and aged≥18 years in Sydney,Australia underwent a digital anorectal examination,anal swab for human papillomavirus(HPV)and p16/Ki67 testing and completeda *** with positive HPV and/or p16/Ki67 results were referred for a high-resolution anoscopy(HRA)and evaluation of their *** Of 52 participants,46 agreed to screening and 6 provided demographic information *** age was 46.5 years(IQR:36.059.0).Anal high-risk HPV(HRHPV)was detected in only seven(15.2%)participants(three HPV16).Eight(17.4%)had positive p16/Ki67 dual staining,with invalid results for 25(54.4%).0f 10 women referred for HRA,9 attended and 3 had HSILs,representing 6.5%of the screened *** were completed by 41 participants(89.1%).The majority reported that being screenedwas reassuring(97.5%)and was positive for their health(95.1%).Conclusion This pilot study demonstrated a lower-than-expected prevalence of anal *** with HRHPV and p16/Ki67 staining identified anal HSILs in 6.5%of ***,screeningwas viewed as beneficial by almost all *** utility of p16/Ki67dual staining was low,suggesting it may not be a suitable anal cancer screening methodology.

关键词： pilot Sydney screening

Role of Toll-like receptors in health and diseases of gastrointestinal tract

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2006年第14期12卷 2149-2160页

作者： Greg Harris rhonda KuoLee Institute for Biological Sciences National Research Council Canada 100 Sussex DriveOttawaONK1A 0R6Canada

The human gastrointestinal （GI） tract is colonized by non-pathogenic commensal microflora and frequently exposed to many pathogenic organisms. For the maintenance of GI homeostasis, the host must discriminate between pathogenic and non-pathogenic organisms and initiate effective and appropriate immune and inflammatory responses. Mammalian tolllike receptors （TLRs） are members of the patternrecognition receptor （PRR） family that plays a central role in the initiation of innate cellular immune responses and the subsequent adaptive immune responses to microbial pathogens. Recent studies have shown that gastrointestinal epithelial cells express almost all TLR subtypes characterized to date and that the expression and activation of TLRs in the GI tract are tightly and coordinately regulated. This review summarizes the current understanding of the crucial dual roles of TLRs in the development of host innate and adaptive immune responses to GI infections and the maintenance of the immune tolerance to commensal bacteria through downregulation of surface expression of TLRs in intestinal epithelial cells.

关键词： Toll-like receptor Gastrointestinal tract Intestinal disease

Intestinal M cells:The fallible sentinels?

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2007年第10期13卷 1477-1486页

作者： Harvey Miller rhonda KuoLee Girishchandra B Patel Institute for Biological Sciences National Research Council Canada 100 Sussex Drive Ottawa Ontario K1A 0R6 Canada

The gastrointestinal tract represents the largest mucosal membrane surface in the human body. The immune system in the gut is the first line of host defense against mucosal microbial pathogens and it plays a crucial role in maintaining mucosal homeostasis. Membranous or microfold cells, commonly referred to as microfold cells, are specialized epithelial cells of the gut-associated lymphoid tissues (GALT) and they play a sentinel role for the intestinal immune system by delivering luminal antigens through the follicle-associated epithelium to the underlying immune cells. M cells sample and uptake antigens at their apical membrane, encase them in vesicles to transport them to the basolateral membrane of M cells, and from there deliver antigens to the nearby lymphocytes. On the flip side, some intestinal pathogens exploit M cells as their portal of entry to invade the host and cause infections. In this article, we briefly review our current knowledge on the morphology, development, and function of M cells, with an emphasis on their dual role in the pathogenesis of gut infection and in the development of host mucosal immunity.

关键词： M cell Gastrointestinal Development Pathogenesis Mucosal immunity

Sequential stenotic strictures of the small bowel leading to obstruction

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2007年第40期13卷 5391-5393页

作者： George Van Buren Ⅱ Davis C Teichgraeber rhonda P Ghorbani Eduardo A Souchon Department of General Surgery The University of Texas Health Science Center at HoustonHoustonTX 77030United States Department of Radiology The University of Texas Health Science Center at HoustonHoustonTX 77030United States Department of Pathology The University of Texas Health Science Center at HoustonHoustonTX 77030United States

Small bowel obstructions （SBOs） are primarily caused by adhesions, hernias, neoplasms, or inflammatory strictures. Intraluminal strictures are an uncommon cause of SBO. This report describes our findings in a unique case of sequential, stenotic intraluminal strictures of the small intestine, discusses the differential diagnosis of intraluminal intestinal strictures, and reviews the literature regarding intraluminal pathology.

关键词： Small bowel obstruction Stenosis Stricture

Collision tumor of the kidney composed of clear cell carcinoma and collecting duct carcinoma: report of a case with unusual morphology and clinical follow-up

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Cancer 2014年第7期33卷 351-355页

作者： rhonda Burch-Smith Nizar M Tannir Erika Resetkova Pheroze Tamboli Priya Rao Department of Pathology MD Anderson Cancer Center Department of Geni-tourinary Medical Oncology MD Anderson Cancer Center

We report the case of a 67-year-old female who presented with a large renal mass. Gross examination of the nephrectomy specimen demonstrated a 6-cm renal mass that invaded into the renal sinus and perinephric fat. Histologic examination revealed two distinct tumor types. The first type was a conventional(clear cell) renal cell carcinoma that was of low nuclear grade and comprised the minority of the overall tumor. The second type was a high-grade collecting duct carcinoma with glandular/tubular differentiation and composed the majority of the tumor. Immunohistochemical studies demonstrated distinctive patterns of the two tumor types, thus confirming two distinct lineages. Five months postoperatively, the patient developed metastasis to the lungs and right hilar lymph node region. A fine needle aspiration of a lung nodule demonstrated a metastatic, poorly differentiated carcinoma, similar to the collecting duct carcinoma component in the kidney. Collision tumors of the kidney are rare with fewer than 10 cases reported in the literature. Our report further expands the spectrum of this rare phenomenon.

关键词：集合管肾细胞肾脏肿瘤病例报告癌组织学检查随访