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Effect of green tea consumption in treatment of mild to moderate depression in Iranian patients living with HIV: A double-blind randomized clinical trial

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Chinese Herbal Medicines 2021年第1期13卷 136-141页

作者： Dehghan Manshadi Seyed ali Mousavi Seyed alireza Salehi Mohammad Reza Zebardast Jayran Seyedalinaghi SeyedAhmad rezazade shams ali Mirhoseinian Seyed Saeid Asadollahi-Amin ali Department of Infectious Diseases and Tropical Medicine Imam-Khomeini Hospital ComplexTehran University of Medical SciencesTehranTehran 11519Iran Department of Infectious Diseases and Tropical Medicine Shahid Sadoughi HospitalShahid Sadoughi University of Medical Sciences and Health ServicesYazd 11519Iran Cognitive Neuroscience Linguistics Institute for Cognitive Science Studies(ICSS)Tehran 11519Iran Iranian Research Center for HIV/AIDS Iranian Institute for Reduction of High-Risk BehaviorsTehran University of Medical SciencesTehran 11519Iran Medicinal Plants Research Center Institute of Medicinal PlantsACECRTehran 11519Iran Department of Pharmacognosy Faculty of Pharmacy.Tehran University of Medical Sciences.Tehran 11519Iran

Objective: Depression affects people living with HIV(PLWH) compliance leading to poor control *** observational studies showed an anti-depression effect of green tea extract(GTE). The therapeutic effect of GTE on depression were investigated in PLWH receiving antiretroviral therapy(ART).Methods: Fifty PLWH on ART with diagnose of mild to moderate of depression, participated in a doubleblind, placebo-controlled trial and underwent 12 weeks of treatment with either 400 mg GTE capsules or placebo twice daily. The Hamilton depression scale of patients was measured before, 6 weeks and 12 weeks after treatment in two groups. The primary outcome measure was performed to evaluate the efficacy of GTE in improving depressive ***: The mean of Hamilton score showed a significant difference between the two groups after 12 weeks(P = 0.035). Repeated measures ANOVA test showed a significant effect for time ? treatment interaction on the Hamilton mean score between the two groups(P = 0.000).Conclusion: It seems the use of GTE capsules in PLWH on ART is safe and could lead to greater and more rapid improvement in depressive symptoms than placebo. Thus it can be considered as an alternative therapy for mild to moderate depression. Further studies with higher sample size and longer followup and comparisons with other antidepressive drugs are warranted.

关键词： depression green tea HIV

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Analyzing the Revitalization Strategies of Historical Fabric with the Approach of Endogenous Development Case Study (1, 2 &3 Regional of Zahedan City)

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Open Journal of Geology 2016年第6期6卷 363-371页

作者： Mahsume Hafez rezazade Razieh Islami Rad Fatemeh Hashemzehi Department of Geography and Urban Planning Faculty of Human Science Zahehan Branch Islamic Azad University Zahedan Iran

Internal development is applying of all the power and existing potential and actual capacities in the city to achieve sustainable and urban participation, and improves all social, physical, economic, and political structures to achieve a sustainable quality and quantity equilibrium. The policy of urban development in the world is to improve the productivity and optimization of land use and the possibility of infill development and improving access of city distressed fabric habitants to urban and social services. In this regard, the present study of Analysis of vitalization strategies of historical fabric with the approach of endogenous development Case study (1, 2 & 3 regional of Zahedan city). The research method is analytic-descriptive and based on library, documentary and field studies and VIKOR model has been also used for data analysis. Based on the results of VIKOR model, the 3 regional of Zahedan city with score 3 and the region 1 with a score of 0.436 were located on the highest and lowest rank. At the end, we suggested strategies according of the research result.

关键词： Historical Fabrics Endogenous Development Zahedan City

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