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Most Frequent Comorbidities in Patients With Lichen Planopilaris:A Cross-Sectional Study

International Journal of Dermatology and Venereology 2023年第4期6卷 229-232页

作者： Kaveh Gharaei Nejad reyhaneh ghadarjani Hojat Eftekhari Saba Sheykholeslami Skin Research Center Razi HospitalGuilan University of Medical SciencesRasht ***Iran Department of Pathology Razi HospitalGuilan University of Medical SciencesRasht ***Iran.

Objective:Lichen planopilaris (LPP) is a rare skin disorder,but it is also the most common cause of scarring alopecia in *** main cause of this disease is unknown,but it is considered to be related to the immune status of the *** comorbidities are reportedly associated with LPP,such as hypertension,depression,thyroiditis,diabetes,and *** the present study,we aimed to investigate the frequency of comorbidities in patients with LPP who were referred to Razi Hospital in Rasht,Iran,from 2016 to ***:This cross-sectional study involved 60 patients with cicatricial alopecia patches (scarring and irreversible) and clinical signs and symptoms consistent with active *** association between demographic data and comorbidities in patients with LPP was evaluated with the chi-square test andt ***:The results showed that the most common comorbidities were vitamin D deficiency (24.3%),hypothyroidism (17.6%),anemia (16.2%),asthma and allergy (14.8%),hypertension (13.5%),diabetes (9.5%),and vitiligo (4.5%).There was no statistically significant association of sex,age,or body mass index with LPP according to the presence or absence of underlying disease (P = 0.440,P = 0.108,andP = 0.340,respectively);however,there was a statistically significant difference in the presence of comorbidities according to age (P = 0.018).Conclusion:The results illustrated that women with vitamin D deficiency are more prone to LPP than are patients with other pre-existing underlying diseases.

关键词： comorbidities lichen planopilaris skin disorder alopecia

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Etiology, Outcome and Mortality Risk Factors in Children Burn

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Surgical Science 2015年第2期6卷 42-49页

作者： Hamid Karimi Seyed Abbas Motevalian Mahnoush Momeni Roya Safari Mitra ghadarjani Faculty of Medicine Iran University of Medical Sciences Tehran Iran Faculty of Health School Iran University of Medical Sciences Tehran Iran Faculty of Medicine Iran University of Medical Sciences Tehran Iran Department of Biostatistics and Epidemiology Faculty of Health School Kerman University of Medical Sciences Kerman Iran Emergency Department Motahary Burn Hospital Iran University of Medical Sciences Tehran Iran

Mortality rate of burn patients can serve as an objective criterion for quality control and as a measure for research and preventive programs. A prospective study of burn victims, from data of burn registry program, was conducted to determine the etiology, risk factors of mortality and outcome of pediatric burns. We had 514 patients below 15 years old. Burns caused by scalding were the most frequent (55.4%) followed by flames (35.8%). Mean (SD) of age was 3.72 (3.19) years. Male to female ratio was 1.62:1. Mean hospital stay was 14.17 days (range 0 - 46 days). The mean TBSA (SD) was 15.22% (14.31%). Fifty three patients had inhalation injury (11.25%). Inhalation injury increases the risk of death (Odds Ratio: 8.75, p = 0.009). Length of stay increased in accordance with burn area (p < 0.002). Burn wound infection was present in (35.4%) of our patients. The univariate statistics analysis and a pooled, cross-sectional, multivariate logistic regression were done. The major risk factors were: Inhalation injury (OR = 8.75, p = 0.009) and lack of intra-venous fluid resuscitation before reaching the hospital (OR = 40.5%, p = 0.001), cause of burn (flame and chemical) and referral cases from other centers (OR = 3.66, p < 0.0001). The minor risk factor was age. About 83% of our patients discharged with partial recovery, 10% with complete recovery, 0.1% referred to other hospitals and 1.36% died.

关键词： Burns Risk Factors Mortality Registry Inhalation Injury

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Relevance of Hepatocyte Growth Factor and Fibroblast Growth Factor on Mouse Preimplantation Embryo Development

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Journal of Reproduction and Contraception 2009年第4期20卷 195-204页

作者： Mohammad Hadi Bahadori Mahnaz Azarnia Fatemeh Ghasemian Fahimeh Ghasemi Shervin ghadarjani Narges Khojasteh Masumeh Ahmadi Jalali Moghaddam Department of Anatomy Faculty of medicineGuilan University of medical sciences Department of Biology Faculty of scienceKharazmi (Tarbiat moallem) university Medical intern Faculty of medicineGuilan University of medical sciences Cellular and molecular research center Faculty of medicineGuilan University of medical sciences

Objective To explore the effect of hepatocyte growth factor （HGF） and fibroblast growth factor （FGF） on preimplantation embryo development of mouse.Methods Mated mice were killed by cervical dislocation to collect two pronucleous （2 PN） zygotes from oviduct of pregnant 1 d NMRI mice and were cultured to the hatching blastocyst stage and the number of embryo in different stages was recorded under an invert microscope. The cleavage rates of formed 2 PN zygotes were compared with blastocyst and hatching blastocyst stage in drops of T6 medium with or without HGF or FGF （0 ng/ml, 10 ng/ml, 20 ng/ml, 50 ng/ml, 1 000 ng/ml）. Results HGF and FGF enriched embryo culture media promotea the aevetopment from 2 PN stage embryos to blastocyst. Adding 20 ng/ml of FGF or HGF to the culture medium significantly increased the percentage of 2PN embryos that developed into blastocysts （P〈0.05）, but culture of embryos in drops of T6 medium with HGF （20 ng/ml） had no improvement in in-vitro hatching.Conclusion Exogenous HGF and FGF at low concentrations promote in-vitro mouse blastocyst formation.

关键词： fibroblast growth factor (FGF) hepatocyte growth factor (HGF) preimplantation development cleavage blastocyst

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Determination of Conversion Coefficient to Evaluate Couple-year of Protection (CYP) for Tubectomy and Vasectomy in Urban and Rural Regions of Iran:IMES Study

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Journal of Reproduction and Contraception 2009年第2期20卷 81-92页

作者： Farzane Alinejad Abtin Heidarzade Mohammad Eslami Roya Faraji Mohsen Shatti Shervin ghadarjani Faculty of Medicine Guilan University of Medical Sciences Dept. of Community medicine Faculty of Medicine Guilan University of Medical Sciences Family Planning Office Family Health Department Ministry of Health Central Building Dept. of Obstetrics and GYN Guilan University of Medical Sciences Monitoring and Evaluation Office Family Health Section Ministry of Health and Medical Education

Objective To calculate couple-year of protection （CYP） by conversion coefficient （F） of tubectomy and vasectomy in urban and rural regions of Iran. Methods A total of 103 450 married women aged 10-49 years in 2005 across urban and rural regions of lran were sampled by multi stage cluster sampling. The data were collected by household survey and direct interview and analyzed by STATA8.0 software and survey analysis commands. Results Mean age of the women at the time of tubectomy estimated 31.9 years and conversion coefficient of tubectomy was 17.1 ±0.1. Mean age of women at the time of her husband vasectomy estimated 31.48 years and its conversion coefficient was 17. 5 ± 0. 1. Cluster analysis defined different regions of Iran on the basis of evaluated conversion coefficients of tubectomy and vasectomy which both of them presented seven clusters. Literacy of women and total coverage of family planning in a region had a direct relationship with this conversion coefficient （P〈0.05）. Conclusion The variations observed in the conversion coefficients and their dissimilarity among different regions of Iran may be due to a variety of fundamental factors of which literacy and culture are of important factors.

关键词： family planning contraception vasectomy tubectomy conversion coefficient (F) couple-year of protection (CYP)

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