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Fluid Leakage in Submerged Offshore Pipeline: An Analysis of Oil Dispersion in Seawater

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Open Journal of Fluid Dynamics 2020年第2期10卷 95-121页

作者： Gicelia Moreira Hortência L. Fernandes Magalhães Daniela P. Simões de Almeida Tavares Balbina R. de brito Correia Boniek E. Leite Adriana B. da Costa Pereira Severino R. de Farias Neto Antonio G. Barbosa de lima department of Chemical Engineering Federal University of Campina Grande Campina Grande Brazil

Leakages in oil pipelines can cause financial losses and several environmental damages, where large-scale offshore oil and gas exploration results in large releases of oil and gas into ocean waters. In the event of oil leakage, an immediate and adequate response is required to reduce environmental damage, such as containment barriers, for example, which depends on the agglomeration of oil particles, velocity and tendency to propagation. Thus, the understanding of the fluid flow behavior around of subsea pipeline at different depths is crucial. On the other hand, the knowledge of interfacial phenomena of immiscible liquids allows the process of adjective migration in submarine pipelines. Consequently, this science enables the prediction of the behavior and the geometric shape of the water-oil interface and provides a phenomenological foundation concerning the theories of perturbation, the stability criteria and mathematical modeling, as well as the flow patterns in the neighborhoods and submerged pipelines. From this perspective, this work aims to study the oil dispersion in sea water caused by leakage in a submerged pipeline. Here, a two-dimensional mathematical model based on the mass and linear momentum conservation equations and the standard k-ε turbulence model, was developed. The dynamic behavior of the oil and water phases is evaluated by pressure fields, surface velocity, volumetric fraction and velocity vectors. Simulation results show the presence of oil flux from the pipe to the marine stream and vice-versa. Further, the increase in oil velocity at the pipe inlet leads to an increase in pressure drop.

关键词： Computational Fluid Dynamics Submerged Offshore Pipeline Leakage CFX

Prevalence and factors associated with non-adherence to therapy among partners of pregnant women with syphilis in a city of northeastern Brazil

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World Journal of Obstetrics and Gynecology 2022年第3期11卷 20-32页

作者： Lilian Pinto Mota Rodrigues Fernandes Caline Novais Teixeira Oliveira Breno Bittencourt de brito FabrícioFreire de Melo Cláudio lima Souza Márcio Vasconcelos Oliveira Instituto Multidisciplinar em Saúde Universidade Federal da BahiaVitória da Conquista 45029-094BahiaBrazil

BACKGROUND One of the main difficulties faced in the prevention of the vertical transmission of syphilis is the inadequate treatment of pregnant women and their *** disease causes serious repercussions in infected *** To evaluate the prevalence and factors associated with the therapeutic adhesion among partners of pregnant women with syphilis in a county in Northeastern *** This is a descriptive,analytic,quantitative,cross-sectional study that was carried out through interviews with 46 pregnant women diagnosed with syphilis between 2017 and 2018 as well as with their *** interviews aimed at collecting data regarding sociodemographic characteristics,obstetric variables and information about syphilis,and partners’related *** Our results showed that 73.91%of the partners did not undergo appropriate treatments,and obtaining negative results in syphilis tests was the main reason for the absence of *** following factors were significantly associated with the lack of treatment among partners:Being a partner that is not the current mate of the pregnant woman,having a level of schooling inferior to 8 years[oddsratio(OR)=10.28],and the pregnant woman undergoing up to two syphilis tests during the prenatal care(OR=8.6).The study found a higher odds of absent treatment among partners if the pregnant woman is not white(OR=13.88)or if the partner has less than 8 years of schooling(OR=21.00)or has a monthly income of less than half the minimum wage(OR=13.93).CONCLUSION The findings of this study show a high prevalence of partners that are not adequately treated for syphilis,a phenomenon that is strongly associated with socioeconomic factors.

关键词： Partners Syphilis Syphilis in pregnancy Treatment Pregnant women Prevalence

Relationship between Th17 immune response and cancer

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World Journal of Clinical Oncology 2021年第10期12卷 845-867页

作者： Hanna Santos Marques Breno Bittencourt de brito Filipe Antônio França da Silva Maria Luísa Cordeiro Santos Júlio César Braga de Souza Thiago Macêdo Lopes Correia Luana Weber Lopes Nayara Silva de Macêdo Neres Rafael Santos Dantas Miranda Dórea Anna Carolina Saúde Dantas Lorena Lôbo brito Morbeck Iasmin Souza lima Amanda Alves de Almeida Maiara Raulina de Jesus Dias Fabrício Freire de Melo Campus Vitória da Conquista Universidade Estadual do Sudoeste da BahiaVitória da Conquista 45083-900BahiaBrazil Instituto Multidisciplinar em Saúde Universidade Federal da BahiaVitória da Conquista 45029-094BahiaBrazil

Cancer is the second leading cause of death worldwide and epidemiological projections predict growing cancer mortality rates in the next *** has a close relationship with the immune system and,although Th17 cells are known to play roles in the immune response against microorganisms and in autoimmunity,studies have emphasized their roles in cancer *** Th17 immune response profile is involved in several types of cancer including urogenital,respiratory,gastrointestinal,and skin *** type of immune response exerts pro and antitumor functions through several mechanisms,depending on the context of each tumor,including the protumor angiogenesis and exhaustion of T cells and the antitumor recruitment of T cells and neutrophils to the tumor *** other factors,the paradoxical behavior of Th17 cells in this setting has been attributed to its plasticity potential,which makes possible their conversion into other types of T cells such as Th17/Treg and Th17/Th1 ***(IL)-17 stands out among Th17-related cytokines since it modulates pathways and interacts with other cell profiles in the tumor microenvironment,which allow Th17 cells to prevail in ***,the IL-17 is able to mediate pro and antitumor processes that influence the development and progression of various cancers,being associated with variable clinical *** understanding of the relationship between the Th17 immune response and cancer as well as the singularities of carcinogenic processes in each type of tumor is crucial for the identification of new therapeutic targets.

关键词： Cancer Immune response Th17 cells Interleukin-17 Tumor microenvironment Pathophysiology

Chronic myeloid leukemia-from the Philadelphia chromosome to specific target drugs:A literature review

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World Journal of Clinical Oncology 2021年第2期12卷 69-94页

作者： Mariana Miranda Sampaio Maria Luísa Cordeiro Santos Hanna Santos Marques Vinícius lima de Souza Gonçalves Glauber Rocha lima Araújo Luana Weber Lopes Jonathan Santos Apolonio Camilo Santana Silva Luana Kauany de SáSantos Beatriz Rocha Cuzzuol Quézia Estéfani Silva Guimarães Mariana Novaes Santos Breno Bittencourt de brito Filipe Antônio França da Silva Márcio Vasconcelos Oliveira Cláudio lima Souza Fabrício Freire de Melo Instituto Multidisciplinar em Saúde Universidade Federal da BahiaVitória da Conquista 45029-094BahiaBrazil Campus Vitória da Conquista Universidade Estadual do Sudoeste da BahiaVitória da Conquista 45083-900BahiaBrazil

Chronic myeloid leukemia(CML)is a myeloproliferative neoplasm and was the first neoplastic disease associated with a well-defined genotypic anomaly―the presence of the Philadelphia *** advances in cytogenetic and molecular assays are of great importance to the diagnosis,prognosis,treatment,and monitoring of *** discovery of the breakpoint cluster region(BCR)-Abelson murine leukemia(ABL)1 fusion oncogene has revolutionized the treatment of CML patients by allowing the development of targeted drugs that inhibit the tyrosine kinase activity of the BCR-ABL *** kinase inhibitors(known as TKIs)are the standard therapy for CML and greatly increase the survival rates,despite adverse effects and the odds of residual disease after discontinuation of *** therapeutic alternatives,the subsequent TKIs lead to faster and deeper molecular remissions;however,with the emergence of resistance to these drugs,immunotherapy appears as an alternative,which may have a cure potential in these *** this background,this article aims at providing an overview on CML clinical management and a summary on the main targeted drugs available in that context.

关键词： Chronic myeloid leukemia Breakpoint cluster region-Abelson murine leukemia Immunotherapy Tyrosine kinase inhibitors Philadelphia chromosome Diagnosis

Evaluation of Quality of Life and Oral Changes of Patients in Head and Neck Radiotherapy: Observational Study

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Journal of Cancer Therapy 2021年第11期12卷 641-653页

作者： Emilly Silva e Silva Gerlane lima Oliveira Ana Carolina Carneiro Cardoso Isabella Melo brito Ferreira Marco Tulio Brazão-Silva Douglas Magno Guimarães dental School Pará University Center Rua Nove de Janeiro Belém Pará Brazil dental School Montes Claros State University Montes Claros Minas Gerais Brazil

Radiotherapy (RT) in the head and neck, despite coming from technological evolution, is challenged by the acute and late side effects of local irradiation, including permanent loss of saliva, osteoradionecrosis, dental caries induced by radiation and necrosis of the oral cavity, mucositis, xerostomia and secondary infections like candidiasis. Since these manifestations are limiting and the integrity of the vital organs contemplates the patient’s general health status, the oral health-related quality of life (OHRQoL) can be significantly affected by the treatment of head and neck cancer (HNC), since cancer can cause important changes in vital functions related to communication, food and social contact, causing disturbances in the patient’s life. An observational and longitudinal study was carried out with 16 cancer patients submitted to RT in the head and neck, between the years 2019-2020 with the objectives of collecting clinical and epidemiological data on the main oral changes caused by RT in the head and neck and correlating them with the impact on OHRQoL. To analyze the OHRQoL, the University of Washington’s Quality of Life Assessment questionnaire (UW-QOL) was applied once a week for 4 weeks and to observe oral manifestations, a dental clinic file standardized by the researchers was applied. The main oral manifestations clinically observed were hyposalivation, trismus and oral mucositis. The UW-QOL presented pain, chewing and taste as the main complaints reported by patients, however, appearance, salivation and chewing showed statistically significant differences over the weeks. The main manifestations observed were hyposalivation, trismus and oral mucositis, the physical limitations resulting from these manifestations i

关键词： Adverse Reactions Head and Neck Neoplasms Radiotherapy

由电阻率测井曲线换算虚速度测井曲线的一种新方法

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石油物探译丛 1989年第1期 22-28页

作者： W. L. brito Dos Santos T. J. Ulrych O. A. L. de lima 高騊

本文介绍了一种利用电阻率值生成虚速度测井曲线的方法。研究出了应用于各种岩性的电阻率与传播时间之间的理论关系。它是利用了一种将岩石电阻率带定义为与实际地层有关的岩性层並能显示电阻率微小变化的方法进行的,这种关系的应用结... 详细信息

本文介绍了一种利用电阻率值生成虚速度测井曲线的方法。研究出了应用于各种岩性的电阻率与传播时间之间的理论关系。它是利用了一种将岩石电阻率带定义为与实际地层有关的岩性层並能显示电阻率微小变化的方法进行的,这种关系的应用结果已在巴西Bahia区的Reconcavo沉积盆地中得到了验证。由五口井换算的虚速度测井曲线与实际声测井曲线对比结果表明了本方法的有效性。

关键词：电阻率测井虚速度测井曲线换算

实施CMMS的五项原则及其使用——一个石化工厂的案例研究

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设备管理与维修 2008年第7期 61-63页

作者： Marcelo Arese[巴西] Gilson brito[巴西] Alves lima[巴西] 王秩信（译）

大多数计算机维修管理系统(CMMS)没有起到管理系统应有的作用,或者实施以后限制了管理的能力。另一个重要的事实是:如果实施时间少于二年,大约有50%的CMMS实施是注定要失败的。笔者采用PeterSenge的观点,把学习组织(Learning Organisati... 详细信息

大多数计算机维修管理系统(CMMS)没有起到管理系统应有的作用,或者实施以后限制了管理的能力。另一个重要的事实是:如果实施时间少于二年,大约有50%的CMMS实施是注定要失败的。笔者采用PeterSenge的观点,把学习组织(Learning Organisations)作为新方法来实施和使用CMMS。探讨如何成功地把这个方法应用于Rio de Janeiro天然气化工厂,保证全面使用CMMS。

关键词：维修 CMMS 管理五项原则

New Anesthetic Technique for Dacryocystorhinostomy: 218 Cases with Local-Anesthesia Ultrasonographic Guided and Blunt Cannula

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Open Journal of Ophthalmology 2021年第4期11卷 282-292页

作者： Hugo C. T. Siqueira Clarissa M. M. Stoffel de Siqueira Marlon Miguel Bianchi de lima Leonardo T. C. Lins department of Anesthesiology Centro de Estudos e Pesquisas Oculistas Associados (CEPOA) Rio de Janeiro Brazil department of Anesthesiology Hospital do Olho (HO) Julio Candido de Brito Duque de Caxias Brazil department of Ophthalmology Centro de Estudos e Pesquisas Oculistas Associados (CEPOA) Rio de Janeiro Brazil department of Oculoplastics Centro de Estudos e Pesquisas Oculistas Associados (CEPOA) Rio de Janeiro Brazil Hospital do Olho (HO) Julio Candido de brito Duque de Caxias Brazil

Introduction: Epiphora is a common ophthalmologic complaint and referrals to oculoplastics and, in the presence of lower complete lacrimonasal duct obstruction, may lead to mild to severe complications, thus requiring surgery to create a new drainage path. The external dacryocystorhinostomy with silicon intubation is the surgical technique with better long-term outcomes and performed in the institutions where this study was conducted. Can be performed under either general or loco-regional anesthesia, or a combination of both. Methods: This article presents a revision of 218 consecutive cases from december 2016 to June 2021 in two specialized centers with the same standardized surgical and anesthetic technique. Results: 242 surgical prontuaries were selected, with 218 filling the inclusion criteria. 13% of the patients required additional anesthetic infusion before the beginning of the surgery;2.7% of the patients required field anesthetic infusion during the surgery and 6.4% required supplementary sedation, thus meaning a positive outcome, as the number of patients with intraoperative complaints was low, and the overall comfort was high. During the follow up, no patient required pain medication after 24 hours. Discussion: This study points towards the feasibility of the described technique in an outpatient fashion, with low, mild and tolerable side effects associated.

关键词： Dacryocystorhinostomy Local Anesthesia Ultrasound

Adsorption of Zinc from Aqueous Solutions Using Modified Brazilian Gray Clay

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American Journal of Analytical Chemistry 2013年第9期4卷 510-519页

作者： Patrícia N. M. Vasconcelos Wellington S. lima Marta L. P. Silva André L. F. brito Hervé M. Laborde Meiry G. F. Rodrigues Federal University of Campina Grande Academic Unit of Chemical Engineering Campina Grande Brasil Rural Federal University of Semi Arid Agrotechnology and Social Science Departamento Mossoró Brasil

In this study, the removal of zinc (Zn2+) from aqueous solutions was investigated using a Na-enriched Brazilian gray clay. The mineral clays were characterized through EDX, XRD analysis and CEC. A finite bath system was used to evaluate the main effects of mechanical agitation (from 100 to 200 rpm), pH values in the range from 6.0 to 8.0 and Zn2+ initial concentrations (from 10 to 50 mg/L) on the removal process capacity. Langmuir and Freundlich isotherm models were applied in order to determine the efficiency of clay used as an adsorbent. According to the obtained results, Langmuir model adjusts very well to the experimental data. Based on the kinetic studies for the Na-enriched gray clay, it was verified that the mechanism corresponds to a predominant pseudo-second order adsorption, presenting a kinetic constant value equal to k = 1.13 (***/mg).

关键词： Adsorption Gray Mineral Clays Zinc Separation of Heavy Metal