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Lymphatic plastic bronchitis and primary chylothorax: A study based on computed tomography lymphangiography

World Journal of Clinical Cases 2024年第14期12卷 2350-2358页

作者： Xing-Peng Li Yan Zhang Xiao-Li Sun Kun Hao Meng-Ke Liu Qi Hao ren-gui wang Department of Radiology Beijing Shijitan Hospital Affiliated to Capital Medical UniversityBeijing 100038China Department of Radiology Qilu HospitalShandong UniversityJinan 250063Shandong ProvinceChina Department of Lymph Surgery Beijing Shijitan Hospital Affiliated to Capital Medical UniversityBeijing 100038China Department of Radiology People's Hospital of Peking UniversityThe Second School of Clinical Medicine of Peking UniversityBeijing 100034China

BACKGROUND This study presents an evaluation of the computed tomography lymphangio-graphy(CTL)features of lymphatic plastic bronchitis(PB)and primary chylotho-rax to improve the diagnostic accuracy for these two *** To improve the diagnosis of lymphatic PB or primary chylothorax,a retrospective analysis of the clinical features and CTL characteristics of 71 patients diagnosed with lymphatic PB or primary chylothorax was *** The clinical and CTL data of 71 patients(20 with lymphatic PB,41 with primary chylothorax,and 10 with lymphatic PB with primary chylothorax)were collected *** was performed in all *** clinical manifestations,CTL findings,and conventional chest CT findings of the three groups of patients were *** chi-square test or Fisher's exact test was used to compare the differences among the three groups.A difference was considered to be statistically significant when P<***(1)The percentages of abnormal contrast medium deposits on CTL in the three groups were as follows:Thoracic duct outlet in 14(70.0%),33(80.5%)and 8(80.0%)patients;peritracheal region in 18(90.0%),15(36.6%)and 8(80.0%)patients;pleura in 6(30.0%),33(80.5%)and 9(90.0%)patients;pericardium in 6(30.0%),6(14.6%)and 4(40.0%)patients;and hilum in 16(80.0%),11(26.8%)and 7(70.0%)patients;and(2)the abnormalities on conven-tional chest CT in the three groups were as follows:Ground-glass opacity in 19(95.0%),18(43.9%)and 8(80.0%)patients;atelectasis in 4(20.0%),26(63.4%)and 7(70.0%)patients;interlobular septal thickening in 12(60.0%),11(26.8%)and 3(30.0%)patients;bronchovascular bundle thickening in 14(70.0%),6(14.6%)and 4(40.0%)patients;localized mediastinal changes in 14(70.0%),14(34.1%),and 7(70.0%)patients;diffuse mediastinal changes in 6(30.0%),5(12.2%),and 3(30.0%)patients;cystic lesions in the axilla in 2(10.0%),6(14.6%),and 2(20.0%)patients;and cystic lesions in the chest wall in 0(0%),2(4.9%),and 2(4.9%)*** CTL is

关键词： Lymphatic Plastic bronchitis Primary chylothorax Direct lymphangiography Computed tomography lymphangiography

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Tuberous sclerosis complex combined with primary lymphedema:A case report

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World Journal of Clinical Cases 2024年第15期12卷 2642-2648页

作者： Xing-Peng Li Xiao-Li Sun Xin Liu Zhe Wen Li-Hua Jiang Yan Fu Yun-Long Yue ren-gui wang Department of Radiology Beijing Shijitan Hospital Affiliated to Capital Medical UniversityBeijing 100038China Department of Lymph Surgery Beijing Shijitan Hospital Affiliated to Capital Medical UniversityBeijing 100038China Department of Nuclear Medicine Beijing Shijitan Hospital Affiliated to Capital Medical UniversityBeijing 100038China Department of MRI Beijing Shijitan Hospital Affiliated to Capital Medical UniversityBeijing 100038China

BACKGROUND Tuberous sclerosis complex(TSC)and primary lymphedema(PLE)are both rare diseases,and it is even rarer for both to occur in the same *** this work,we have provided a detailed description of a patient's clinical presentation,imaging findings,and *** a retrospective analysis was conducted on 14 published relevant case *** SUMMARY A 16-year-old male came to our hospital for treatment due to right lower limb *** swelling is already present from *** patient’s memory had been progressively *** had occurred 1 year prior at an unknown *** patient was diagnosed with TSC combined with PLE through multimodal imaging examination:Computed tomography,magnetic resonance imaging,and *** patient underwent *** swelling of the patient's right lower limb significantly improved after *** did not *** taking antiepileptic drugs and *** TSC with PLE is a rare and systemic *** can detect lesions of this disease,which are important for diagnosis and treatment.

关键词： Tuberous sclerosis complex Lymphedema Sirolimus Multimodal imaging examination Case report

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Relationship between Radiological Stages and Prognoses of Pneumocystis Pneumonia in Non-AIDS Immunocompromised Patients

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Chinese Medical Journal 2016年第17期129卷 2020-2025页

作者： Xiang-Dong Mu Peng Jia Li Gao Li Su Cheng Zhang ren-gui wang Guang-Fa wang Department of Respiratory and Critical Care Medicine Peking University First Hospital Beijing 100034 China Department of Radiology Peking University First Hospital Beijing 100034 China Department of Radiology Beijing Shijitan Hospital Beijing 100038 China

Background： Although radiological features ofpneumocystis pneumonia （PCP） in non-Acquired Immune Deficiency Syndrome （AIDS） immunocompromised patients have been reported by other authors, there were no studies on the radiological stages of PCP previously. This study aimed to elucidate the radiological stages and prognoses of PCP in non-AIDS immunocompromised patients. Methods： Retrospective analysis ofradiological manifestations and prognoses of 105 non-AIDS PCP immunocompromised patients from August 2009 to April 2016 was conducted. Chest radiograph was divided into three stages： early stage （normal or nearly normal chest radiograph）, mid stage （bilateral pulmonary infiltrates）, and late stage （bilateral pulmonary consolidations）; chest high-resolution computed tomography （HRCT） was also divided into three stages： early stage （bilateral diffuse ground-glass opacity [GGO]）, mid stage （bilateral diffuse GGO and patchy consolidations）, and late stage （bilateral diffuse consolidations）. Results： The case fatality rate （CFR） of all patients was 34.3% （36/105）, all of them took routine chest X-ray （CXR）, and 84 underwent chest CT examinations. According to the CXR most near the beginning ofanti-PCP therapy, 18 cases were at early stage and CFR was 0 （0/18, P 〈 0.01）, 50 cases were at mid stage and CFR was 28.0% （14/50, P〉 0.05）, and 37 cases were at late stage and CFR was 59.5% （22/37, P 〈 0.01）. According to the chest HRCT most near the beginning ofanti-PCP therapy, 40 cases were at early stage and CFR was 20.0% （8/40, P 〉 0.05）, 34 cases were at mid stage and CFR was 47.1% （l 6/34, P 〉 0.05）, and 10 cases were at late stage and CFR was 80.0% （8/10, P 〈 0.05）; barotrauma, including pneumothorax, pneumomediastinum, and pneumohypoderma, was found in 18 cases and the CFR was 77.8% （14/18, P 〈 0.01）. Conclusions： Based on the radiological manifestations, the course of PCP in non-A1DS immunocompromised patients can be divided into three stages： early stage, mid stage, and la

关键词： Immunocompromised Patients Pneumocystis Pneumonia Prognosis Radiological Stages

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Endoscopic classification and pathological features of primary intestinal lymphangiectasia

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World Journal of Gastroenterology 2022年第22期28卷 2482-2493页

作者： Ming-Ming Meng Kui-Liang Liu Xin-Ying Xue Kun Hao Jian Dong Chun-Kai Yu Hong Liu Cang-Hai wang Hui Su Wu Lin Guo-Jun Jiang Nan Wei ren-gui wang Wen-Bin Shen Jing Wu Department of Gastroenterology Beijing Shijitan HospitalCapital Medical UniversityBeijing 100038China Department of Respiratory and Critical Care Medicine Beijing Shijitan HospitalCapital Medical UniversityBeijing 100038China Departments of Lymphatic Surgery Beijing Shijitan HospitalCapital Medical UniversityBeijing 100038China Departments of Radiology Beijing Shijitan HospitalCapital Medical UniversityBeijing 100038China Departments of Pathology Beijing Shijitan HospitalCapital Medical UniversityBeijing 100038China

BACKGROUND The appearance of the intestinal mucosa during endoscopy varies among patients with primary intestinal lymphangiectasia(PIL).AIM To classify the endoscopic features of the intestinal mucosa in PIL under endoscopy,combine the patients’imaging and pathological characteristics of the patients,and explain their *** We retrospectively analyzed the endoscopic images of 123 patients with PIL who were treated at the hospital between January 1,2007 and December 31,*** compared and analyzed all endoscopic images,classified them into four types according to the endoscopic features of the intestinal mucosa,and analyzed the post-lymphographic computed tomography(PLCT)and pathological characteristics of each *** According to the endoscopic features of PIL in 123 patients observed during endoscopy,they were classified into four types:nodular-type,granular-type,vesicular-type,and *** showed diffuse thickening of the small intestinal wall,and no contrast agent was seen in the small intestinal wall and mesentery in the patients with nodular and granular *** agent was scattered in the small intestinal wall and mesentery in the patients with vesicular and edematous *** of the small intestinal mucosal pathology revealed that nodular-type and granulartype lymphangiectasia involved the small intestine mucosa in four layers,whereas ectasia of the vesicular-and edematous-type lymphatic vessels largely involved the lamina propria mucosae,submucosae,and muscular *** Endoscopic classification,combined with the patients’clinical manifestations and pathological examination results,is significant and very useful to clinicians when scoping patients with suspected PIL.

关键词： Primary intestinal lymphangiectasia Endoscopic features Post-lymphangiographic computed tomography Pathology

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Relationship between radiological stages and prognoses of Pneumocystis jiroveci pneumonia in non-AIDS Immunocompromized patients

Relationship between radiological stages and prognoses of Pn...

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中华医学会呼吸病学年会——2013（第十四次全国呼吸病学学术会议）

作者： Xiangdong MU Li GAO ren-gui wang Li SU Cheng ZHANG Guang-fa wang Peking University First Hospital

Objective To elucidate the radiological stages and prognoses of Pneumocystis jiroveci pneumonia(PCP) in non-AIDS immunocopromised patients. Methods Retrospective analysis of radiological manifestations and prognoses of 50 non-AIDS PCP immunocopromised patients from August 2006 to 2011. Chest radiograph were divided into 3 stages:early stage(normal or near-normal Chest radiograph),mid stage(bilateral pulmonary infiltrates) and late stage (bilateral pulmonary consolidations);chest HRCT were also divided into 3 stages:early stage(bilateral

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用光纤光栅作外反馈的可调谐外腔半导体激光器

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中国激光 2001年第2期28卷 113-115页

作者：周凯明葛璜安贵仁汪孝杰王圩中国科学院半导体研究所北京100083

制作了一种以光纤光栅作为外反馈的半导体激光器。光纤光栅用紫外曝光法制作 ,反射率为 5 0 %。器件在5 0mA注入电流时 ,出纤功率高于 1mW ,主边模抑制比为 42dB。使用对光纤光栅施加应变和改变光栅温度的方法实现了输出激光波长的调谐 ... 详细信息

制作了一种以光纤光栅作为外反馈的半导体激光器。光纤光栅用紫外曝光法制作 ,反射率为 5 0 %。器件在5 0mA注入电流时 ,出纤功率高于 1mW ,主边模抑制比为 42dB。使用对光纤光栅施加应变和改变光栅温度的方法实现了输出激光波长的调谐 ,利用施加应变方法得到了 2nm范围的输出波长变化。

关键词：光纤光栅半导体激光器可调谐外腔结构外反馈

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Progress of research in the application of ultrasound technology for the treatment of Alzheimer’s disease

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Neural Regeneration Research 2025年第10期20卷 2823-2837页

作者： Qiuquan Cai Lianghui Meng Meina Quan Ling wang Jing ren Chenguang Zheng Jiajia Yang Dong Ming Academy of Medical Engineering and Translational Medicine Tianjin UniversityTianjinChina Innovation Center for Neurological Disorders Xuanwu HospitalCapital Medical UniversityBeijingChina Brain-Computer Interaction and Human-Machine Fusion Haihe Laboratory Tianjin UniversityTianjinChina Tianjin Key Laboratory of Brain Science and Neural Engineering Tianjin UniversityTianjinChina

Alzheimer’s disease is a common neurodegenerative disorder defined by decreased reasoning abilities,memory loss,and cognitive *** presence of the blood-brain barrier presents a major obstacle to the development of effective drug therapies for Alzheimer’s *** use of ultrasound as a novel physical modulation approach has garnered widespread attention in recent *** a safe and feasible therapeutic and drug-delivery method,ultrasound has shown promise in improving cognitive *** article provides a summary of the application of ultrasound technology for treating Alzheimer’s disease over the past 5 years,including standalone ultrasound treatment,ultrasound combined with microbubbles or drug therapy,and magnetic resonance imaging-guided focused ultrasound *** is placed on the benefits of introducing these treatment methods and their potential *** found that several ultrasound methods can open the blood-brain barrier and effectively alleviate amyloid-βplaque *** believe that ultrasound is an effective therapy for Alzheimer’s disease,and this review provides a theoretical basis for future ultrasound treatment methods.

关键词： Alzheimer’s disease blood-brain barrier drugs magnetic resonance imaging-guided focused ultrasound microbubbles scanning ultrasound ultrasound ultrasound stimulation

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T cell interactions with microglia in immune-inflammatory processes of ischemic stroke

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Neural Regeneration Research 2025年第5期20卷 1277-1292页

作者： Yuxiao Zheng Zilin ren Ying Liu Juntang Yan Congai Chen Yanhui He Yuyu Shi Fafeng Cheng Qingguo wang Changxiang Li Xueqian wang School of Traditional Chinese Medicine Beijing University of Chinese MedicineBeijingChina Library Beijing University of Chinese MedicineBeijingChina Dongzhimen Hospital Beijing University of Chinese MedicineBeijingChina

The primary mechanism of secondary injury after cerebral ischemia may be the brain inflammation that emerges after an ischemic stroke,which promotes neuronal death and inhibits nerve tissue *** the first immune cells to be activated after an ischemic stroke,microglia play an important immunomodulatory role in the progression of the *** an ischemic stroke,peripheral blood immune cells(mainly T cells)are recruited to the central nervous system by chemokines secreted by immune cells in the brain,where they interact with central nervous system cells(mainly microglia)to trigger a secondary neuroimmune *** review summarizes the interactions between T cells and microglia in the immune-inflammatory processes of ischemic *** found that,during ischemic stroke,T cells and microglia demonstrate a more pronounced synergistic ***1,Th17,and M1 microglia can co-secrete proinflammatory factors,such as interferon-γ,tumor necrosis factor-α,and interleukin-1β,to promote neuroinflammation and exacerbate brain ***2,Treg,and M2 microglia jointly secrete anti-inflammatory factors,such as interleukin-4,interleukin-10,and transforming growth factor-β,to inhibit the progression of neuroinflammation,as well as growth factors such as brain-derived neurotrophic factor to promote nerve regeneration and repair brain *** interactions between microglia and T cells influence the direction of the subsequent neuroinflammation,which in turn determines the prognosis of ischemic stroke *** trials have been conducted on the ways to modulate the interactions between T cells and microglia toward anti-inflammatory communication using the immunosuppressant fingolimod or overdosing with Treg cells to promote neural tissue repair and reduce the damage caused by ischemic ***,such studies have been relatively infrequent,and clinical experience is still *** summary,in ischemic stroke,T cell subsets and activated micro

关键词： brain immune inflammation interaction ischemic stroke mechanism microglia neuron secondary injury T cells

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正常成人肺HRCT呼气相密度改变的定量研究

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实用放射学杂志 2001年第6期17卷 401-404页

作者：谢晟王仁贵王仪生蒋学祥北京医科大学第一医院放射科!北京100034

目的　研究正常成人肺HRCT呼气相表现和对其进行定量分析。方法　分析 97例 2 0～ 70岁健康志愿者的肺呼气相HRCT表现 ,计算双肺吸呼气相密度差值 (VD)、面积缩小率 (AR)、呼气相上左前、左后、右前、右后肺局部区域的密度值 (LD) ,并... 详细信息

目的　研究正常成人肺HRCT呼气相表现和对其进行定量分析。方法　分析 97例 2 0～ 70岁健康志愿者的肺呼气相HRCT表现 ,计算双肺吸呼气相密度差值 (VD)、面积缩小率 (AR)、呼气相上左前、左后、右前、右后肺局部区域的密度值 (LD) ,并对其进行统计学分析。结果　左肺与右肺之间 ,上肺与下肺之间的VD和AR存在显著性差异 ;前肺与后肺的LD有显著性差异 ;双肺的VD和AR有显著性相关。结论　健康成人的肺呼气相HRCT上各区域间存在着密度差异。

关键词：肺 HRCT 呼气相

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Limiting Case of 1D Delta Anyon Model

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Communications in Theoretical Physics 2008年第12期50卷 1265-1268页

作者： ZHU ren-gui wang An-Min College of Physics and Electronic Information Anhui Normal University Wuhu 241000 China Department of Modern Physics University of Science and Technology of China Hefei 230026 China

In order to analyze a limiting case of the 1D delta anyon model,the coupling strength of the δ interactionc is modified to become a function of the anyonic parameter κ.A pedagogic derivation of the solution for this modifiedmodel using the method of anyon-boson mapping plus Bethe ansatz is *** limiting case as κ→π andsimultaneously c→0,which was previously neglected,is *** unexpected properties of this limiting case *** BAEs are compared with previous results.

关键词： anyon Bethe ansatz

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