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Microstructure and water-swelling mechanism of red-bed mudstone in the Xining region,Northeastern Tibetan Plateau

Journal of Rock Mechanics and Geotechnical Engineering 2024年第7期16卷 2537-2551页

作者： Huan Guan Yong ren Sixiang Ling Xiyong Wu Tao Yu Xian Li Sen Wang Chunwei sun School of Civil Engineering Southwest Jiaotong UniversityChengdu610031China Faculty of Geosciences and Engineering Southwest Jiaotong UniversityChengdu611756China Moe Key Laboratory of High-speed Railway Engineering Southwest Jiaotong UniversityChengdu610031China Guangzhou Metro Design and Research Institute Co Ltd. Guangzhou510010China Chengdu City Construction Investment Group Co Ltd. Chengdu610036China

This paper examines the effect of the microstructure and electrical conductivity(EC)on the swelling ratio and pressure in red-bed mudstone sampled from arid areas in the Xining region in the northeastern Tibetan Plateau.A series of laboratory tests,including swelling experiments,X-ray diffraction(XRD),and scanning electron microscope(SEM),was carried out for mechanical and microstructural *** coupled influence of the EC and microstructural parameters on the expansion ratio and pressure was investigated,and the weight coefficients were discussed by the entropy weight *** results revealed an increasing exponential trend in EC,and the maximum swelling speed occurred at an EC of approximately 10 μS/*** addition,a method for predicting the expansion potential is proposed based on the microstructure,and its reliability is verified by comparing with swelling experimental *** addition,according to the image analysis results,the ranges of the change in the clay minerals content(CMC),the fractal dimension(FD),the average diameter(AD)of pores,and the plane porosity(PP)are 23.75%-53%,1.08-1.17,7.53-22.45 mm,and 0.62%-1.25%,***,mudstone swelling is negatively correlated with the plane porosity,fractal dimension and average diameter and is linearly correlated with the clay mineral ***,the weight values prove that the microstructural characteristics,including FD,AD,and PP,are the main factors influencing the expansion properties of red-bed mudstones in the Xining *** on the combination of macro and micro-analyses,a quantitative analysis of the swelling process of mudstones can provide a better reference for understanding the mechanism of expansion behavior.

关键词： Mudstones Microstructure Swelling characteristics Electrical conductivity(EC) Scanning electron microscope Water-swelling

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Reorganization of 3D genome architecture provides insights into pathogenesis of early fatty liver disease in laying hens

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Journal of Animal Science and Biotechnology 2024年第3期15卷 1086-1100页

作者： Yanli Liu Zhuqing Zheng Chaohui Wang Yumeng Wang Xi sun Zhouzheng ren Xin Yang Xiaojun Yang College of Animal Science and Technology Northwest A&F UniversityYangling 712100China Institute of Agricultural Biotechnology Jingchu University of TechnologyJingmen 448000China

Background Fatty liver disease causes huge economic losses in the poultry industry due to its high occurrence and lethality ***-dimensional(3D)chromatin architecture takes part in disease processing by regulating tran-scriptional *** study is carried out to investigate the alterations of hepatic 3D genome and H3K27ac profiling in early fatty liver(FLS)and reveal their effect on hepatic transcriptional reprogramming in laying *** Results show that FLS model is constructed with obvious phenotypes including hepatic visible lipid deposi-tion as well as higher total triglyceride and cholesterol in serum.A/B compartment switching,topologically associat-ing domain(TAD)and chromatin loop changes are identified by high-throughput/resolution chromosome conforma-tion capture(HiC)*** genes of these alternations in hepatic 3D genome organization significantly enrich pathways related to lipid metabolism and hepatic damage.H3K27ac differential peaks and differential expres-sion genes(DEGs)identified through RNA-seq analysis are also enriched in these ***,certain DEGs are found to correspond with changes in 3D chromatin structure and H3K27ac binding in their *** motif analysis reveals that candidate transcription factors are implicated in regulating transcriptional ***,disturbed folate metabolism is observed,as evidenced by lower folate levels and altered enzyme *** Our findings establish a link between transcriptional reprogramming changes and 3D chromatin struc-ture variations during early FLS formation,which provides candidate transcription factors and folate as targets for FLS prevention or treatment.

关键词： 3D chromatin architecture Fatty liver disease Folate H3K27ac profiling Transcription reprogramming

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Toward quantum unmanned systems

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Science China(Technological Sciences) 2024年第7期67卷 2277-2280页

作者： CHENG ShuMing QI HongSheng sun Yue LIU LiJun XIE ShaoRong ren XiaoQiang Department of Control Science and Engineering Tongji UniversityShanghai 200092China Academy of Mathematics and Systems Science Chinese Academy of SciencesBeijing 100190China Cipher Cloud Core Ltd. Beijing 100085China College of Mathematics and Computer Science Shanxi Normal UniversityLinfen 041081China School of Computer Engineering and Science Shanghai UniversityShanghai 200444China School of Mechatronic Engineering and Automation Shanghai UniversityShanghai 200444China

1 Quantum information technology Quantum information technology utilizes physical systems at the microscopic level, such as photon, atom, ion, and superconducting, to accomplish information-processing tasks that are impossible for the classical macroscopic world. During the past decade, significant process has been achieved in the pursuit of quantum technology into practical applications,generating great research interest from various domains, with the potential to radically change our information infrastructure [1–3].

关键词： quantum utilize generating

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CFD investigation of structural effects of internal gas intake on powder conveying performance in fuel supply systems for aerospace engines

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颗粒学报（英文版） 2024年第9期92卷 140-154页

作者： Guanlong ren Haijun sun Fangjun Chen Wen Shen Yunzhen Cai Yihua Xu Henrik Ström Bilainu Oboirien Qingang Xiong School of Aircraft Engineering Nanchang Hangkong UniversityNanchang330063China Engineering Research Center of Aero-engine Technology for General Aviation Ministry of EducationNanchang330063China State Key Laboratory of Pulp and Paper Engineering South China University of TechnologyGuangzhou510640China School of Aircraft Engineering Nanchang Hangkong UniversityNanchang330063China Engineering Research Center of Aero-engine Technology for General Aviation Ministry of EducationNanchang330063China State Key Laboratory of Pulp and Paper Engineering South China University of TechnologyGuangzhou510640China Department of Mechanics and Maritime Sciences Chalmers University of TechnologyGöteborg412 96Sweden Department of Chemical Engineering University of JohannesburgJohannesburg17011South Africa

Optimal design of gas intake in powder fuel supply systems is crucial for performance of aerospace *** is little research on the impact of intake structure on powder conveying *** novel internal intakes were proposed,which are spherical,cube-shaped,and *** validation,CFD simulations demonstrate that fluctuation of mass flow rate of powders in the dome-shaped intake is reduced by about 73.3％compared with the annular external *** trends of phase velocities are similar for the spherical and cube-shaped intakes,while those are similar for the annular external and dome-shaped internal *** of area of gas zone for the annular external and spherical internal intakes is larger than that for the cube-shaped and dome-shaped internal *** and relative pressure drop in the fluidization chamber have a stable stage,and fluc-tuation of relative pressure drop is small when dome-shaped internal intake is used.

关键词： Dense gas-solid flow Intake structure Powder fluidization Powder supply system Pressure drop Two-fluid model

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Double-Doped Carbon-Based Electrodes with Nitrogen and Oxygen to Boost the Areal Capacity of Zinc-Bromine Flow Batteries

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Transactions of Tianjin University 2024年第1期30卷 74-89页

作者： Xiaoyun sun Deren Wang Haochen Hu Xin Wei Lin Meng Zhongshan ren Sensen Li Institute for Advanced Materials and Technology University of Science and TechnologyBeijing 100083China School of Physics and Materials Engineering Hefei Normal UniversityHefei 230601China Jiangsu Heng’an Energy Storage Technology Co. Ltd.Beijing 100176China

Ensuring a stable power output from renewable energy sources,such as wind and solar energy,depends on the development of large-scale and long-duration energy storage ***–bromine fl ow batteries(ZBFBs)have emerged as cost-eff ective and high-energy-density solutions,replacing expensive all-vanadium fl ow ***,uneven Zn deposition during charging results in the formation of problematic Zn dendrites,leading to mass transport polarization and *** Zn plating and stripping are essential for the successful operation of high-areal-capacity *** this study,we successfully synthesized nitrogen and oxygen co-doped functional carbon felt(NOCF4)electrode through the oxidative polymerization of dopamine,followed by calcination under ambient *** NOCF4 electrode eff ectively facilitates effi cient“shuttle deposition”of Zn during charging,signifi cantly enhancing the areal capacity of the ***,ZBFBs utilizing NOCF4 as the anode material exhibited stable cycling performance for 40 cycles(approximately 240 h)at an areal capacity of 60 mA h/cm^(2).Even at a high areal capacity of 130 mA h/cm^(2),an impressive energy effi ciency of 76.98%was *** fi ndings provide a promising pathway for the development of high-areal-capacity ZBFBs for advanced energy storage systems.

关键词： Zinc-bromine fl ow batteries N,O co-doping Areal capacity Shuttle deposition Zinc dendrite

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Hepatocellular carcinoma:An analysis of the expression status of stress granules and their prognostic value

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World Journal of Gastrointestinal Oncology 2024年第6期16卷 2571-2591页

作者： Qing-Shuai ren Qiu sun Shu-Qin Cheng Li-Ming Du Ping-Xuan Guo Department of Cardiovascular Surgery North China University of Science and Technology Affiliated HospitalTangshan 063000Hebei ProvinceChina Department of Hepatobiliary Kailuan General HospitalTangshan 063000Hebei ProvinceChina Department of Gastroenterology and Hepatology Tianjin Medical University General HospitalTianjin Institute of Digestive DiseasesTianjin Key Laboratory of Digestive DiseasesTianjin 300000China Department of Traditional Chinese Medicine Kailuan General HospitalTangshan 063000Hebei ProvinceChina Department of Anesthesiology Kailuan General HospitalNorth China University of Science and TechnologyTangshan 063000Hebei ProvinceChina

BACKGROUND Hepatocellular carcinoma(HCC)is a global popular malignant tumor,which is difficult to cure,and the current treatment is *** To analyze the impacts of stress granule(SG)genes on overall survival(OS),survival time,and prognosis in *** The combined The Cancer Genome Atlas-Liver Hepatocellular Carcinoma(TCGA-LIHC),GSE25097,and GSE36376 datasets were utilized to obtain genetic and clinical *** hub gene numbers and corresponding coefficients were determined using the Least absolute shrinkage and selection operator model approach,and genes for constructing risk scores and corresponding correlation coefficients were calculated according to multivariate Cox regression,*** prognostic model’s receiver operating characteristic(ROC)curve was produced and plotted utilizing the time ROC software *** models were constructed to predict the outcomes at 1,3,and 5-year OS prognostications with good prediction *** We identified seven SG genes(DDX1,DKC1,BICC1,HNRNPUL1,CNOT6,DYRK3,CCDC124)having a prognostic significance and developed a risk score *** findings of Kaplan-Meier analysis indicated that the group with a high risk exhibited significantly reduced OS in comparison with those of the low-risk group(P<0.001).The nomogram model’s findings indicate a significant enhancement in the accuracy of OS prediction for individuals with HCC in the TCGA-HCC *** Ontology and Gene Set Enrichment Analysis suggested that these SGs might be involved in the cell cycle,RNA editing,and other biological *** Based on the impact of SG genes on HCC prognosis,in the future,it will be used as a biomarker as well as a unique therapeutic target for the identification and treatment of HCC.

关键词： Stress granule genes Hepatocellular carcinoma Gastrointestinal neoplasms Bioinformatics prognosis Prognostic value

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High-tenacity in-situ Ti/Zr-based bulk metallic glasses composites fabricated by industrial high-pressure die casting

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Journal of Materials Science & Technology 2024年第3期170卷 177-185页

作者： Yang Li Wenbo Luo Ying Jin Zhiyong Xue Guiqing Wang Yanan ren Haoxin Li Haibo Ke Baoan sun Weihua Wang Institute for Advanced Materials North China Electric Power UniversityBeijing 102206China Songshan Lake Materials Laboratory Dongguan 523808China Institute of Physics Chinese Academy of SciencesBeijing 100190China

The glass-forming ability and mechanical properties of metallic glasses and their composites are well known to be sensitive to the preparation conditions and are highly deteriorated by industrial preparing conditions such as low-purity raw materials and low ***,we showed that a series of in-situ bulk metallic glass composites(BMGCs)which exhibit excellent ductility and segmental work hardening were successfully developed utilizing a high vacuum high-pressure die casting(HV-HPDC)technology along with industrial-grade raw *** tensile properties of these BMGCs are systematically investigated and correlated with the alloy *** compared with the copper mold suction casting method,the volume fraction difference of the dendrite phase for the BMGCs with the same composition is not significant when fabricated by the HV-HPDC,whereas the size of theβ-phase is generally *** BMGCs with the composition of Ti_(48)Zr_(20)(V_(12/17)Cu_(5/17))19 Be 13 obtained by the HV-HPDC process show ductility up to 11.3%under tension at room temperature and exhibit a certain amount of work *** conditions need to be met to enable the BMGCs,which are prepared by vacuum die-casting to retain favorable ductility:(1)The volume fraction ofβphase stays below 62%±2%;(2)The equiaxed crystals with a more uniform size in the range of 5-10μ***,the results of the present study provided guidance for developing BMGCs with good ductile properties under industrial conditions.

关键词： Vacuum die casting Bulk metallic glass composites Mechanical properties β-phase

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Weather and Birth Weight:Different Roles of Maternal and Neonatal GPR61 Promoter Methylation

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Biomedical and Environmental Sciences 2022年第3期35卷 181-193页

作者： LI Zhi Yuan GONG Yong Xiang YANG Meng CHAI Jian sun ren Jie LI Qin Yang HE Ya Nan HUANG Hui ZHANG Ya Wei BA Yue ZHOU Guo Yu Department of Environmental Health&Environment and Health Innovation Team School of Public HealthZhengzhou UniversityZhengzhou 450001HenanChina National Health Commission Key Laboratory of Birth Defects Prevention Henan Key Laboratory of Population Defects PreventionHenan Institute of Reproduction Health Science and TechnologyZhengzhou 450002HenanChina Yellow River Institute for Ecological Protection&Regional Coordinated Development Zhengzhou UniversityZhengzhou 450001HenanChina Department of Environment Health Science Yale University School of Public HealthNew HavenCTUSA

Objectives It is unclear whether G protein-coupled receptor 61(GPR61)affecting body weight,plays a role in the association between birth weight and *** study aimed to assess the effects of prenatal weather and GPR61 on birth *** A total of 567 mother-newborn pairs were recruited in Houzhai Center Hospital during2011–*** detected the maternal and neonatal GPR61 promoter methylation levels,and obtained meteorological and air pollution *** A positive association was observed between maternal and neonatal GPR61 methylation levels,and both of them were affected by precipitation,relative humidity(RH)and daily temperature range(DTR).Birth weight was associated negatively with RH and positively with DTR(Prenatal weather,GPR61 methylation and birth *** GPR61 methylation may modify the susceptibility of birth weight to prenatal weather conditions,while neonatal GPR61 methylation may be a bridge of the effects of prenatal RH and DTR on birth weight.

关键词： Pregnancy Weather Birth weight GPR61 gene DNA methylation Mother-newborns

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关于两个球体在Stokes流中解的收敛性问题

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水动力学研究与进展（A辑） 2006年第5期21卷 667-671页

作者：孙仁上海交通大学工程力学系上海200240

Stokes流绕两个球体流动问题是3连通域的外流问题。此问题的解是由一系列调和函数和双调和函数项的级数表达式线形组合而成。文中探讨这些表达式在两个球体接触情况下的收敛性问题。通过收敛性的判断得出了当一个球体向另一个平面接近时... 详细信息

Stokes流绕两个球体流动问题是3连通域的外流问题。此问题的解是由一系列调和函数和双调和函数项的级数表达式线形组合而成。文中探讨这些表达式在两个球体接触情况下的收敛性问题。通过收敛性的判断得出了当一个球体向另一个平面接近时,这些解中的系数的级数表达式不收敛;而当两个球体互相接近甚至接触时,其解中的系数的级数表达式收敛。这就为流场中物体的相互接触问题的进一步研究打下了基础。

关键词： Stokes方程两体问题多连通域外流问题水动力学相互作用

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控温、系统温度和外载荷对纳米通道中水流性质的影响

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水动力学研究与进展（A辑） 2020年第6期35卷 719-725页

作者：刘桦孙仁上海交通大学水动力学教育部重点实验室上海200240

该文采用非平衡分子动力学模拟的方法,研究了控温方式、系统温度和外载荷对纳米管道中水流的密度、温度和流速的径向分布的影响。控温方式的不同,会导致纳米管道的热传递方式不同,进而影响管道中水流的热传递和速度;系统温度和外载荷在... 详细信息

该文采用非平衡分子动力学模拟的方法,研究了控温方式、系统温度和外载荷对纳米管道中水流的密度、温度和流速的径向分布的影响。控温方式的不同,会导致纳米管道的热传递方式不同,进而影响管道中水流的热传递和速度;系统温度和外载荷在不同控温方式下会对管道中的水流造成不同的影响。该文综合以上三种因素,发现高外载荷作用下,纳米管道的壁面温度会对水流性质产生较大的影响。

关键词：分子动力学控温方式系统温度外载荷

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