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China Geology 2024年第1期7卷 36-50页

作者： Jin-feng ren Hai-jun Qiu Zeng-gui Kuang Ting-wei Li Yu-lin He Meng-jie Xu Xiao-xue Wang Hong-fei Lai Jin Liang National Engineering Research Center of Gas Hydrate Exploration and Development Guangzhou 511458China Guangzhou Marine Geological Survey China Geological SurveyGuangzhou 511458China China Geological Survey Ministtry of Natural ResourcesBeijing 100037China

Many locations with concentrated hydrates at vents have confirmed the presence of abundant thermogenic gas in the middle of the Qiongdongnan Basin(QDNB).However,the impact of deep structures on gasbearing fluids migration and gas hydrates distribution in tectonically inactive regions is still *** this study,the authors apply high-resolution 3. seismic and logging while drilling(LWD)data from the middle of the QDNB to investigate the influence of deep-large faults on gas chimneys and preferred gasescape *** findings reveal the following:(1)Two significant deep-large faults,F1 and F2,developed on the edge of the Songnan Low Uplift,control the dominant migration of thermogenic hydrocarbons and determine the initial locations of gas chimneys.(2)The formation of gas chimneys is likely related to fault activation and *** chimney 1 is primarily arises from convergent fluid migration resulting from the intersection of the two faults,while the gas chimney 2 benefits from a steeper fault plane and shorter migration distance of fault F2.(3.Most gas-escape pipes are situated near the apex of the two *** reactivations facilitate free gas flow into the GHSZ and contribute to the formation of fracture‐filling hydrates.

关键词： Venting gas hydrates Deep-large faults Gas chimney Gas-escape pipes High-resolution 3. seismic Logging while drilling Qiongdongnan Basin South China Sea

Hydroxysafflor Yellow A Inhibits Pyroptosis and Protecting HUVECs from OGD/R via NLRP3.Caspase-1/GSDMD Pathway

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Chinese Journal of Integrative Medicine 2024年第11期30卷 1027-1034页

作者： GUO Fan HAN Xiao YOU Yue XU Shu-juan ZHANG Ye-hao CHEN Yuan-yuan XIN Gao-jie LIU Zi-xin ren Jun-guo CAO Ce LI Ling-mei FU Jian-hua Institute of Basic Medical Sciences of Xiyuan Hospital China Academy of Chinese Medical Sciences Beijing Key Laboratory of Chinese Materia Pharmacology Department of Central Laboratory Kunshan Hospital of Chinese Medicine

Objective: To observe the protective effect and mechanism of hydroxyl safflower yellow A(HSYA)from myocardial ischemia-reperfusion injury on human umbilical vein endothelial cells(HUVECs). Methods:HUVECs were treated with oxygen-glucose deprivation reperfusion(OGD/R) to simulate the ischemia reperfusion model, and cell counting kit-8 was used to detect the protective effect of different concentrations(1.25–160 μmol/L)of HSYA on HUVECs after OGD/R. HSYA 80 μmol/L was used for follow-up experiments. The contents of inflammatory cytokines interleukin(IL)-18, IL-1β, monocyte chemotactic protein 1(MCP-1), tumor necrosis factor α(TNF-α) and IL-6 before and after administration were measured by enzyme-linked immunosorbent assay. The protein expressions of toll-like receptor, NOD-like receptor containing pyrin domain 3.NLRP3., gasdermin D(GSDMD) and GSDMD-N-terminal domain(GSDMD-N) before and after administration were detected by Western blot. NLRP3.inflammasome inhibitor cytokine release inhibitory drug 3.sodium salt(CRID3.sodium salt, also known as MCC950) and agonist were added, and the changes of NLRP3. cysteine-aspartic acid protease 1(Caspase-1), GSDMD and GSDMD-N protein expressions were detected by Western blot. Results: HSYA inhibited OGD/R-induced inflammation and significantly decreased the contents of inflammatory cytokines IL-18,IL-1β, MCP-1, TNF-α and IL-6(P3.Caspase-1/GSDMD pathway, HSYA can reduce the occurrence of pyroptosis after OGD/R and reduce the expression of NLRP3.Caspase-1, GSDMD and GSDMD-N proteins(P3.inflammasome and inhibiting pyroptosis.

关键词： Chinese medicine NLRP3.inflammasome human umbilical vein endothelial cells hydroxysafflor yellow A myocardial reperfusion injury oxygen-glucose deprivation reperfusion pyroptosis

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水热法制备高熵碳酸盐及其颜色特征

硅酸盐学报 2024年第6期52卷 1987-1995页

作者：任洁杨铎时军王晶大连交通大学材料科学与工程学院辽宁大连116028

高熵碳酸盐固溶体因其鲜艳的色彩可被应用于颜料领域,同时其较高的近红外反射率也有用作隔热材料的潜能。本实验采用水热法,通过改变单一组元Cu、Fe和Mn,保持其他4组元为MgCoNiZn不变,制备出3.五元等摩尔高熵碳酸盐固溶体。利用X射线... 详细信息

高熵碳酸盐固溶体因其鲜艳的色彩可被应用于颜料领域,同时其较高的近红外反射率也有用作隔热材料的潜能。本实验采用水热法,通过改变单一组元Cu、Fe和Mn,保持其他4组元为MgCoNiZn不变,制备出3.五元等摩尔高熵碳酸盐固溶体。利用X射线衍射仪、扫描电子显微镜、紫外–可见–近红外分光光度计、CIE 1976 L*a*b*色度坐标、Kubelka-Munk函数分析等对所合成的陶瓷粉体的晶体结构、颜色性能、反射性能等进行表征。结果表明,3.五元素组合均形成了单相高熵碳酸盐,且随着Cu^(2+)、Fe^(2+)、Mn^(2+)半径逐渐增大,晶格常数相应增大。通过组元的改变可以调节高熵碳酸盐的颜色,第5组元为Fe^(2+)时呈橙红色,Cu^(2+)时呈灰绿色,Mn^(2+)时呈浅紫色,相应的禁带宽度值也逐渐增大,吸收边缘相应的发生蓝移。此外还测得3.样品在780~2 500 nm波段具有不同的近红外反射率,最高可达78.64%,有望在高反射隔热材料领域进行应用开发。

关键词：高熵陶瓷碳酸盐固溶体水热法颜色表征近红外反射

不同方式急性运动对超重个体抑制功能的影响——基于行为和事件相关电位的研究

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中国运动医学杂志 2024年第7期43卷 537-545页

作者：孙波任杰上海体育大学竞技运动学院上海200438 上海体育大学中国乒乓球学院上海200438

目的:探讨急性高强度间歇运动(high-intensity interval exercise,HIIE)和急性持续中等强度有氧运动(continuous moderate-intensity aerobic exercise,CMIAE)对超重个体冲突抑制功能的影响。方法:采取被试内设计,以超重个体(n=28)为研究对象,采用行为测量和事件相关电位(event-related potential,ERP)技术,记录超重个体完成认知任务(Flanker任务)时的大脑活动变化,比较急性HIIE和CMIAE对超重个体冲突抑制功能行为表现和大脑活动特征的影响。结果:1)与安静对照条件和急性HIIE相比,急性CMIAE条件下Flanker任务P3.幅显著提高(P0.05);2)与安静对照条件和急性CMIAE相比,急性HIIE条件下Flanker任务反应时缩短(P3.幅与安静对照条件和急性CMIAE相比无显著差异(P>0.05);3.Flanker任务正确率运动条件主效应不显著(P>0.05)。结论:1)急性HIIE和急性CMIAE运动对超重个体冲突抑制具有促进作用,但行为和神经电生理表现有所不同,急性CMIAE可增强超重个体大脑唤醒水平,而急性HIIE可能通过加速认知刷新速率提升冲突抑制表现,推测两种运动对超重个体冲突抑制的调控可能存在不同机制;2)由于本研究中HIIE方案时长更短,因此推测急性HIIE对于超重个体冲突抑制的促进可能是一种更为省时有效的运动方式。

关键词：急性运动超重冲突抑制功能 ERP

不同方式急性运动对超重个体食物抑制功能的影响——来自行为和ERP的证据

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中国体育科技 2024年第3期60卷 65-73页

作者：孙波任杰上海体育大学上海200438

目的:探讨急性高强度间歇运动(high-intensity interval exercise,HIIE)和持续中等强度有氧运动(continuous moderate-intensity aerobic exercise,CMIAE)对超重个体食物抑制功能的影响。方法:采取被试内设计,以超重个体(n=28)为研究对象,选取与食物相关的刺激材料,通过行为测量和事件相关电位技术探讨急性HIIE和CMIAE对超重个体食物Go/NoGo反应时和正确率以及脑神经活动N2、P3.幅的影响。结果:1)2种运动干预后被试完成食物Go/NoGo任务中Go试次的反应时显著更短(P3.在Cz电极上,仅在安静对照条件下,食物NoGo试次中高热量食物图片的P3.幅显著高于Go试次(P0.05)。结论:1)超重个体对食物类刺激存在早期的注意偏向;2)急性HIIE和CMIAE可降低超重个体对高热量食物注意资源的分配;3.急性HIIE对于提升超重个体的食物抑制能力可能是一种更为省时有效的运动方案。

关键词：急性运动超重抑制功能事件相关电位

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Surface-derived phosphate layer on NiFe-layered double hydroxide realizes stable seawater oxidation at the current density of 1 A·cm^(−2)

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Nano Research 2024年第7期17卷 5786-5794页

作者： Chaoxin Yang Zhengwei Cai jie Liang Kai Dong Zixiao Li Hang Sun Shengjun Sun Dongdong Zheng Hui Zhang Yongsong Luo Yongchao Yao Yan Wang Yuchun ren Qian Liu Luming Li Wei Chu Xuping Sun Bo Tang College of Chemistry Chemical Engineering and Materials ScienceShandong Normal UniversityJinan 250014China Institute of Fundamental and Frontier Sciences University of Electronic Science and Technology of ChinaChengdu 610054China Department of Science and Environmental Studies Faculty of Liberal Arts and Social Sciencethe Education University of Hong KongHong Kong 999077China Institute for Advanced Study Chengdu UniversityChengdu 610106China Laoshan Laboratory Qingdao 266237China

Seawater electrolysis,especially in coastlines,is widely considered as a sustainable way of making clean and high-purity H2 from renewable energy;however,the practical viability is challenged severely by the limited anode durability resulting from side reactions of chlorine ***,we report an effective Cl^(−) blocking barrier of NiFe-layer double hydroxide(NiFe-LDH)to harmful chlorine chemistry during alkaline seawater oxidation(ASO),a pre-formed surface-derived NiFe-phosphate(Pi)***,the PO_(4)^(3.)-enriched outer-layer is capable of physically and electrostatically inhibiting Cl−adsorption,which protects active Ni^(3.)sites during *** NiFe-LDH with the NiFe-Pi outer-layer(NiFe-LDH@NiFe-Pi)exhibits higher current densities(j)and lower overpotentials to afford 1 A·cm^(−2)(η1000 of 3.0 mV versusη1000 of 420 mV)than the NiFe-LDH in 1 M KOH+***,the NiFe-LDH@NiFe-Pi also demonstrates longer-term electrochemical durability than NiFe-LDH,attaining 100-h duration at the j of 1 A·cm^(−2).Additionally,the importance of surface-derived PO_(4)^(3.)-enriched outer-layer in protecting the active centers,γ-NiOOH,is explained by ex situ characterizations and in situ electrochemical spectroscopic studies.

关键词： seawater oxidation phosphate outer-layer layered double hydroxide electrostatic repulsion in situ Raman

Clinical feasibility of laparoscopic left lateral segment liver resection with magnetic anchor technique:The first clinical study from China

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World Journal of Gastrointestinal Surgery 2024年第5期16卷 1336-1343页

作者： Miao-Miao Zhang Ji-Gang Bai Dong Zhang jie Tao Zhi-Min Geng Zhuo-Qun Li Yu-Xiang ren Yu-HanZhang Yi Lyu Xiao-Peng Yan Department of Hepatobiliary Surgery The First Affiliated Hospital of Xi’an Jiaotong UniversityXi’an 710061Shaanxi ProvinceChina Shaanxi Provincial Key Laboratory of Magnetic Medicine The First Affiliated Hospital of Xi’an Jiaotong UniversityXi’an 710061Shaanxi ProvinceChina Zonglian College Xi’an Jiaotong UniversityXi’an 710061Shaanxi ProvinceChina Qide College Xi’an Jiaotong UniversityXi’an 710061Shaanxi ProvinceChina

BACKGROUND Magnetic anchor technique(MAT)has been applied in laparoscopic cholecystectomy and laparoscopic appendectomy,but has not been reported in laparoscopic partial *** To evaluate the feasibility of the MAT in laparoscopic left lateral segment liver *** Retrospective analysis was conducted on the clinical data of eight patients who underwent laparoscopic left lateral segment liver resection assisted by MAT in our department from July 2020 to November *** Y-Z magnetic anchor devices(Y-Z MADs)was independently designed and developed by the author of this paper,which consists of the anchor magnet and magnetic grasping *** time,intraoperative blood loss,intraoperative accidents,operator experience,postoperative incision pain score,postoperative complications,and other indicators were evaluated and *** All eight patients underwent a MAT-assisted laparoscopic left lateral segment liver resection,including three patients undertaking conventional 5-port and five patients having a transumbilical single-port *** mean operation time was 13.±3..3. min(range 95-185 min)and the mean intraoperative blood loss was 123.88.60 mL(range 20-3.0 mL).No adverse events occurred during the *** Y-Z MADs showed good workability and maneuverability in both tissue and organ *** particular,the operators did not experience either a“chopstick”or“sword-fight”effect in the single-port laparoscopic *** The results show that the MAT is safe and feasible for laparoscopic left lateral segment liver resection,especially,exhibits its unique abettance for transumbilical single-port laparoscopic left lateral segment liver resection.

关键词： Magnetosurgery/magnetic surgery Magnetic anchor technique Laparoscopic hepatectomy Transumbilical singleport laparoscopy Magnet

Study on Effects of Short Circuit Between High and Common Ends of LVDT's Lead Wires on Sum Voltage

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International Journal of Plant Engineering and Management 2024年第3期29卷 142-153页

作者： HE Zhiheng BAO Yan SHANG jie ren Zhengjia PI Ligang ZHAO Yiyue AVIC Xi′an Flight Automatic Control Research Institute Xi′an 710065China

The Linear variable differential transformer(LVDT)is widely used in the aircraft field and crucial to the safety of the *** on the short-circuit failure mode between the high and common ends of the LVDT′s lead wires,the theoretical formula of short-circuit sum voltage was deduced and verified via ***,the effects of the core length and the winding resistance on the short-circuit sum voltage were analyzed and discussed through numerical *** present research put forward some references for LVDT′s design.

关键词： LVDTs sum voltage short circuit

Succinylation modification:a potential therapeutic target in stroke

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Neural Regeneration Research 2024年第4期19卷 781-787页

作者： jie Lian Wenwu Liu Qin Hu Xiaohua Zhang Department of Neurosurgery Ren Ji HospitalShanghai Jiao Tong University School of Medicine Department of Diving and Hyperbaric Medicine Naval Medical CenterNaval Medical University

Stroke is a leading cause of mortality and disability *** cell death triggered by the compromised supply of blood oxygen and glucose is one of the major pathophysiology of strokeinduced brain *** mitochondrial energy metabolism is observed minutes after stroke and is closely associated with the progression of ***,a new type of posttranslational modification,known as lysine succinylation,has been recognized to play a significant role in mitochondrial energy metabolism after ***,the role of succinylation modification in cell metabolism after stroke and its regulation are not well *** aimed to review the effects of succinylation on energy metabolism,reactive oxygen species generation,and neuroinflammation,as well as Sirtuin 5 mediated desuccinylation after *** also highlight the potential of targeting succinylation/desuccinylation as a promising strategy for the treatment of *** succinylation level is dynamically regulated by the nonenzymatic or enzymatic transfer of a succinyl group to a protein on lysine residues and the removal of succinyl catalyzed by *** evidence has suggested that succinylation can regulate the metabolic pathway through modulating the activity or stability of metabolic ***,especially Sirtuin 5,are characterized for their desuccinylation activity and have been recognized as a critical regulator of metabolism through desuccinylating numerous metabolic *** between succinylation and desuccinylation has been implicated in the pathophysiology of *** agents that enhance the activity of Sirtuin 5 have been employed to promote desuccinylation and improve mitochondrial metabolism,and neuroprotective effects of these agents have been observed in experimental stroke ***,their therapeutic efficacy in stroke patients should be validated.

关键词： mitochondria metabolism neuroprotection sirtuin 5 stroke succinylation modification

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电化学酰胺化反应中间体的原位质谱分析

质谱学报 2024年第1期45卷 131-140,I0004页

作者：羊雪惠人杰胡军江南大学生命科学与健康工程学院江苏无锡214200

酰胺键是一种广泛存在的重要化学键,既是构建蛋白质和多肽的核心,也是多种药物分子的活性中心。近年来,基于电化学的酰胺化反应以高选择性、环境友好等优势受到广泛关注,然而,受限于反应过程的复杂性以及缺乏适当的分析技术,其原位监测... 详细信息

酰胺键是一种广泛存在的重要化学键,既是构建蛋白质和多肽的核心,也是多种药物分子的活性中心。近年来,基于电化学的酰胺化反应以高选择性、环境友好等优势受到广泛关注,然而,受限于反应过程的复杂性以及缺乏适当的分析技术,其原位监测和机理研究却鲜有报道。本研究通过在纳升电喷雾喷针尖端集成金属工作电极的方式构建了一种新型耦合接口,实现了电化学与质谱的在线联用。基于该技术原位监测了以三苯基膦为缩合剂的芳伯胺酰胺化反应过程,并实现了其中多种关键中间体,特别是一些短寿命自由基中间体的鉴定。该电化学-质谱耦合接口具有延迟低、样品耗量小、制备简单等优点,有望成为电有机合成反应快速筛选和机理研究的重要工具。

关键词：酰胺化反应自由基中间体原位质谱三苯基膦

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