检索结果-南通市图书馆

Optimization of Electrolyte Conductivity for Li-ion Batteries Based on Mass Triangle Model

在线全文

学校读者我要写书评

暂无评论

Chemical Research in Chinese Universities 2013年第1期29卷 116-120页

作者： ren Yong-huan WU Bo-rong MUDao-bin YANG Chun-wei ZHANG Cun-zhong WU Feng School of Chemical Engineering and Environment Beijing Higher Institution Engineering Research Center of Power Battery and Chemical Energy Materials Beo'ing Institute of Technology Beijing 100081 P. R. China

Mass triangle model was applied to lithium ion battery for electrolyte conductivity forecasting. Seven kinds of electrolytes with different proportions of 3 solvents were prepared. The solvent proportions of the seven electrolytes varied so as to make the seven coordinate points distribute in the ternary coordinate system to form a forcasting region by the connection of them. Their conductivities were tested and the conductivity value in the forecasting region was calculated based on the tested value by mass triangle model. Conductivity isolines formed in the region and blank area showing no forecasted value existed simultaneously. Optimized electrolyte with superior conductivity was selected according to conductivity variation trendency combined with the attention paid to the no-value-shown blank area. The conductivity of optimized electrolytefre[ethyl carbonate（EC）]：m[propylene carbonate（PC）]：m[ethylmethyl carbonate（EMC）]=0.19：0.22：0.59} was 0.745 mS/cm at-40℃, increased by a factor of 51.4% compared to 0.492 mS/cm of common electrolyte[m（EC）：m（PC）：m（EMC）=l：l：l]. The accuracy of mass triangle model was demonstrated from the perspective that the maximum value existed in the blank area, Batteries with this optimized electrolyte exhibited a better performance.

关键词： Mass triangle model Low temperature Li-ion battery Electrolyte

中草药中金属元素含量对聚丙烯酸类增稠剂的影响

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

日用化学品科学 2024年第7期47卷 43-48页

作者：缪明琴刘文王玉珂任环宇张廷志水羊化妆品制造有限公司创新研发中心上海200000

测定了11款常用化妆品级中草药提取物的14种金属元素含量,并通过电导率测定法分析金属元素含量与电导率关系。结果表明,中草药提取物中K、Na、Mg、Ca含量最高,且中草药提取物有效成分含量越高,金属离子越高,呈正相关;中草药提取物的电... 详细信息

测定了11款常用化妆品级中草药提取物的14种金属元素含量,并通过电导率测定法分析金属元素含量与电导率关系。结果表明,中草药提取物中K、Na、Mg、Ca含量最高,且中草药提取物有效成分含量越高,金属离子越高,呈正相关;中草药提取物的电导率与金属元素含量存在正相关性,电导率高的中草药提取物,金属元素含量都较高。中草药提取物中带入的微量金属元素会降低体系黏度,影响化妆品配方稳定性。根据分子交联度筛选出6款代表性的聚丙烯酸类增稠剂,进行耐离子性能测试,结果表明,聚丙烯酸类交联度越低,耐离子性能越强。

关键词：中草药提取物金属元素交联度复配

同方期刊数据库

MEMS Huygens Clock Based on Synchronized Micromechanical Resonators

在线全文

学校读者我要写书评

暂无评论

Engineering 2024年第5期36卷 124-131页

作者： Xueyong Wei Mingke Xu Qiqi Yang Liu Xu a Yonghong Qi Ziming ren Juan ren Ronghua huan Zhuangde Jiang State Key Laboratory for Manufacturing System Engineering Xi’an Jiaotong UniversityXi’an 710049China School of Construction Machinery Chang’an UniversityXi’an 710064China Department of Mechanics Zhejiang UniversityHangzhou 310027China

With the continuous miniaturization of electronic devices,microelectromechanical system(MEMS)oscillators that can be combined with integrated circuits have attracted increasing *** study reports a MEMS Huygens clock based on the synchronization principle,comprising two synchronized MEMS oscillators and a frequency compensation *** MEMS Huygens clock improved shorttime stability,improving the Allan deviation by a factor of 3.73 from 19.3 to 5.17 ppb at 1 s.A frequency compensation system based on the MEMS oscillator’s temperature-frequency characteristics was developed to compensate for the frequency shift of the MEMS Huygens clock by controlling the resonator *** effectively improved the long-term stability of the oscillator,with the Allan deviation improving by 1.6343105 times to 30.9 ppt at 6000 *** power consumption for compensating both oscillators simultaneously is only 2.85 mW·℃^(-1).Our comprehensive solution scheme provides a novel and precise engineering solution for achieving high-precision MEMS oscillators and extends synchronization applications in MEMS.

关键词： Frequency stability Huygens clock MEMS Oscillator Synchronization

Antiangiogenic therapy with bevacizumab in recurrent malignant gliomas： analysis of the response and core pathway aberrations

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Medical Journal 2009年第11期122卷 1250-1254页

作者： ZHANG Wei QIU Xiao-guang CHEN Bao-shi LI Shou-wei CUI Yun ren huan JIANG Tao Department of Neurosurgery Beijing Tiantan Hospital Capital Medical University Beijing 100050 China Department of Radiotherapy Beijing Tiantan Hospital Capital Medical University Beijing 100050 China Department of Neuropathology Beijing Neurosurgical Institute Beijing 100050 China Department of Immunology College of Basic Medical Science Harbin Medical University Harbin 150086 China

Background Bevacizumab, a humanized monoclonal antibody against vascular endothelial growth factor, has shown promising activity in recurrent malignant gliomas. We reported the treatment response for the combination of bevacizumab and chemotherapy in a series of six patients with recurrent malignant glioma and investigated the molecular alterations in cancer pathways using the surgical biopsies from these patients. Methods Standard therapy with primary resection followed by adjuvant chemoradiotherapy had failed in all patients. Bevacizumab was administered at a dose of 10 mg/kg every 2 weeks. Concomitantly, four patients received temozolomide （50 mg·m^-2·d^-1）, one patient irinotecan （125 mg/m^2 every 2 weeks） and one patient topotecan （1.2 mg·m^-2·d^-1）. Response to therapy was mainly determined by magnetic resonance imaging. The expression of Ras, phosphorylated mitogen activated protein kinase （p-MAPK）, phosphorylated AKT （p-AKT）, phosphorylated mammalian target of rapamycin （p-mTOR） and phosphorylated signal transducer and activator of transcription 3 （p-STAT3） were semiquantitatively assessed by immunohistochemistry using surgical biopsies before the initial treatment. Results Five of the six patients had a radiographic response. Three were complete response, and two were partial response. Only one patient had progressive disease. The 6-month progession-free survival （PFS） was 33% and the median PFS was 15 weeks, with a range of 6 to more than 60 weeks. Of the three core pathways analyzed in this study, the Ras/MAPK and phosphatidylinositol-3-kinase （PI3K）/AKT/mTOR pathways were more likely to be associated with the treatment response to bevacizumab. In two younger patients （ages 〈50） with complete response, simultaneous overexpression of p-MAPK, p-AKT and p-mTOR might be the crucial feature. Conclusions Bevacizumab in combination with chemotherapeutic agents may be an effective strategy for patients with recurrent malignant glioma. Activated MAPK and AKT might

关键词： glioma molecularly targeted therapy bevacizumab antiangiogenic therapy

Machine learning for fault diagnosis of high-speed train traction systems: A review

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Frontiers of Engineering Management 2024年第1期11卷 62-78页

作者： huan WANG Yan-Fu LI Jianliang ren Department of Industrial Engineering Tsinghua UniversityBeijing 100084China Zhibo Lucchini Railway Equipment Co. Ltd.Taiyuan 030032China

High-speed trains(HSTs)have the advantages of comfort,efficiency,and convenience and have gradually become the mainstream means of *** the operating scale of HSTs continues to increase,ensuring their safety and reliability has become more *** the core component of HST,the reliability of the traction system has a substantially influence on the *** the long-term operation of HSTs,the core components of the traction system will inevitably experience different degrees of performance degradation and cause various failures,thus threatening the running safety of the ***,performing fault monitoring and diagnosis on the traction system of the HST is *** recent years,machine learning has been widely used in various pattern recognition tasks and has demonstrated an excellent performance in traction system fault *** learning has made considerably advancements in traction system fault diagnosis;however,a comprehensive systematic review is still lacking in this *** paper primarily aims to review the research and application of machine learning in the field of traction system fault diagnosis and assumes the future development ***,the structure and function of the HST traction system are briefly ***,the research and application of machine learning in traction system fault diagnosis are comprehensively and systematically ***,the challenges for accurate fault diagnosis under actual operating conditions are revealed,and the future research trends of machine learning in traction systems are discussed.

关键词： high-speed train traction systems machine learning fault diagnosis

基于SEER数据库构建骨肉瘤患者肺转移及生存预后的风险预测模型

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

巴楚医学 2024年第3期7卷 50-57页

作者：王壮壮任欢刘彦廷田春雷艾文兵谷城县人民医院骨外科湖北医药学院三峡大学第一临床医学院(宜昌市中心人民医院)神经外科宜昌市夷陵医院神经外科

目的：为探索骨肉瘤患者临床特征与肺转移之间的关系，建立骨肉瘤肺转移发生风险的预测模型，并分析骨肉瘤肺转移患者的生存预后。方法：收集2010—2015年美国国家癌症研究中心(SEER)数据库中2 300例骨肉瘤患者，采用单因素及多因素Logi... 详细信息

目的：为探索骨肉瘤患者临床特征与肺转移之间的关系，建立骨肉瘤肺转移发生风险的预测模型，并分析骨肉瘤肺转移患者的生存预后。方法：收集2010—2015年美国国家癌症研究中心(SEER)数据库中2 300例骨肉瘤患者，采用单因素及多因素Logistic回归分析骨肉瘤患者发生肺转移的独立影响因素，并构建列线图模型。采用受试者工作特征曲线(ROC)、校正曲线和决策曲线分析(DCA)衡量列线图模型的检验效能。最后采用单因素及多因素Cox回归分析骨肉瘤肺转移患者的预后情况。结果：多因素Logistic回归分析结果提示，较高的T分期、有淋巴结转移、不接受手术、接受放化疗是骨肉瘤患者发生肺转移的独立危险因素，基于这些因素构建列线图模型。ROC曲线、校准曲线和DCA曲线显示出列线图模型具有良好的准确性、一致性及临床适用性。Cox回归结果提示，高龄(≥60岁)、不接受手术、不接受放化疗是影响骨肉瘤肺转移患者生存预后的危险因素。结论：较高的T分期、有淋巴结转移不接受手术、接受放化疗是骨肉瘤患者发生肺转移的独立危险因素，高龄(≥60岁)、不接受放化疗是影响骨肉瘤肺转移患者生存预后的危险因素，有助于骨科医生对骨肉瘤患者发生肺转移的风险及预后做出较为准确的评估。

关键词：骨肉瘤肺转移列线图风险预测模型

Prognostic factors influencing clinical outcomes of glioblastoma multiforme

在线全文

学校读者我要写书评

暂无评论

Chinese Medical Journal 2009年第11期122卷 1245-1249页

作者： LI Shou-wei QIU Xiao-guang CHEN Bao-shi ZHANG Wei ren huan WANG Zhong-cheng JIANG Tao Department of Neurosurgery Beijing Tiantan Hospital Affiliated to Capital Medical University Beijing 100050 China Department of Radiotherapy Beijing Tiantan Hospital Affiliated to Capital Medical University Beijing 100050 China Department of Immunology Harbin Medical University Harbin Heilongjiang 150086 China Beijing-Neurosurgical Institute Beijing 100050 China

Background Glioblastoma multiforme （GBM） is the most malignant kind of astrocytic tumors and is associated with a poor prognosis. In this retrospective study, we assessed the clinical, radiological, genetic molecular and treatment factors that influence clinical outcomes of patients with GBM. Methods A total of 116 patients with GBM who received surgery and radiation between January 2006 and December 2007 were included in this study. Kaplan-Meier survival analysis and Cox regression analysis were used to find the factors independently influencing patients＇ progression free survival （PFS） time and overall survival （OS） time. Results Age, preoperative Karnofsky Performance Scale （KPS） score, KPS score change at 2 weeks after operation, neurological deficit symptoms, tumor resection extent, maximal tumor diameter, involvement of eloquent cortex or deep structure, involvement of brain lobe, Ki-67 expression level and adjuvant chemotherapy were statistically significant factors （P 〈0.05） for both PFS and OS in the univariate analysis. Cox proportional hazards modeling revealed that age 〈50 years, preoperative KPS score 〉80, KPS score change after operation 〉0, involvement of single frontal lobe, non-eloquent area or deep structure involvement, low Ki-67 expression and adjuvant chemotherapy were independent favorable factors （P 〈0.05） for patients＇ clinical outcomes. Conclusions Age at diagnosis, preoperative KPS score, KPS score change at 2 weeks postoperation, involvement of brain lobe, involvement of eloquent cortex or deep structure, Ki-67 expression level and adjuvant chemotherapy correlate significantly with the prognosis of patients with GBM.

关键词： glioblastoma multiforme prognostic factor disease progression survival chemotherapy

基于SEER数据库使用列线图对四肢骨肉瘤发生肺转移风险预测模型的构建与验证

在线全文

学校读者我要写书评

暂无评论

临床荟萃 2024年第5期39卷 413-419页

作者：王壮壮任欢刘彦廷田春雷艾文兵谷城县人民医院骨外科湖北襄阳441700 湖北医药学院湖北十堰442000 三峡大学第一临床医学院神经外科湖北宜昌443003 宜昌市夷陵医院神经外科湖北宜昌443003

目的构建列线图模型来预测四肢骨肉瘤患者的肺转移风险。方法收集2010-2020年SEER数据库中1610例四肢骨肉瘤患者,按照7∶3的比例将数据分为训练集与验证集。采用单因素及多因素logistic回归分析四肢骨肉瘤患者发生肺转移的独立影响因素... 详细信息

目的构建列线图模型来预测四肢骨肉瘤患者的肺转移风险。方法收集2010-2020年SEER数据库中1610例四肢骨肉瘤患者,按照7∶3的比例将数据分为训练集与验证集。采用单因素及多因素logistic回归分析四肢骨肉瘤患者发生肺转移的独立影响因素,并构建列线图模型。采用受试者工作特征曲线、Calibration校准曲线和决策曲线分析来评价列线图模型的检验效能。结果Logistic回归结果显示,较高的T分期、发生淋巴结转移、拒绝接受手术、接受放化疗为四肢骨肉瘤患者发生肺转移的独立危险因素(P<0.05)。训练集预测四肢骨肉瘤发生肺转移的最佳受试者工作特征曲线下面积为0.801,验证集受试者工作特征曲线下面积为0.640;训练集与验证集曲线吻合良好;决策曲线分析显示列线图模型预测概率阈值在较大范围内临床净收益较高。结论本研究所构建的四肢骨肉瘤患者发生肺转移风险的列线图模型具有良好的预测精度及临床实用性,有助于骨科医生对四肢骨肉瘤患者做出更快、更可靠的临床预测,提供个体化诊疗方案。

关键词：骨肉瘤肿瘤转移 SEER数据库列线图风险预测

维普期刊数据库博看期刊

吡咯并喹啉醌二钠盐对修护皮肤屏障的作用研究

在线全文

学校读者我要写书评

暂无评论

日用化学品科学 2024年第9期47卷 26-30,68页

作者：夷磊彭怡依任环宇左丽娜张廷志熬夜肌实验室系统工程(上海)有限公司上海200000

通过人角质形成细胞划痕修护测试、斑马鱼胚胎尾鳍修护促进测试、胶带剥离损伤皮肤屏障修护测试和人体临床测试,对吡咯并喹啉醌二钠盐对修护皮肤屏障的作用进行研究,结果表明,吡咯并喹啉醌二钠盐含量为2.5μg/mL时,对人角质形成细胞划... 详细信息

通过人角质形成细胞划痕修护测试、斑马鱼胚胎尾鳍修护促进测试、胶带剥离损伤皮肤屏障修护测试和人体临床测试,对吡咯并喹啉醌二钠盐对修护皮肤屏障的作用进行研究,结果表明,吡咯并喹啉醌二钠盐含量为2.5μg/mL时,对人角质形成细胞划痕有愈合效果;浓度为100μg/mL时,能显著促进斑马鱼胚胎尾鳍再生,并对人体皮肤屏障具有长期修护效果。

关键词：吡咯并喹啉醌二钠盐角质细胞修护