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Adaptive State-Dependent Diffusion for Derivative-Free Optimization

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Communications on Applied Mathematics and Computation 2024年第2期6卷 1241-1269页

作者： Bjorn Engquist Kui ren Yunan Yang Department of Mathematics and the Oden Institute The University of TexasAustinTX 78712USA Department of Applied Physics and Applied Mathematics Columbia UniversityNew YorkNY10027USA Department of Mathematics Cornell UniversityIthacaNY 14853USA

This paper develops and analyzes a stochastic derivative-free optimization strategy.A key feature is the state-dependent adaptive *** prove global convergence in probability with algebraic rate and give the quantitative results in numerical examples.A striking fact is that convergence is achieved without explicit information of the gradient and even without comparing different objective function values as in established methods such as the simplex method and simulated *** can otherwise be compared to annealing with state-dependent temperature.

关键词： Derivative-free optimization Global optimization Adaptive diffusion Stationary distribution Fokker-Planck theory

Yemazhui(Herba Eupatorii Lindleyani)ameliorates lipopolysaccharide-induced acute lung injury via modulation of the toll-like receptor 4/nuclear factor kappa-B/nod-like receptor family pyrin domain-containing 3 protein signaling pathway and intestinal flor

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Journal of Traditional Chinese Medicine 2024年第2期44卷 303-314页

作者： ren Li HAI Yang YAnG Xue LUO Xianqin Chongqing Key Laboratory of Traditional Chinese Medicine for Prevention and Cure of Metabolic Diseases College of Traditional Chinese MedicineChongqing Medical UniversityChongqing 400016China College of Basic Medicine Chongqing Medical UniversityChongqing 400016China

OBJECTIVE:To investigate the impact of Yemazhui(Herba Eupatorii Lindleyani,HEL)against lipopolysaccharide(LPS)-induced acute lung injury(ALI)and explore its underlying mechanism in ***:The chemical constituents of HEL were analyzed by ultra-high performance liquid chromatographyquadrupole time-of-flight mass spectrometry ***,HEL was found to suppress LPS-induced ALI in ***-week-old male Sprague-Dawley rats were randomly divided into 6 groups:control,LPS,Dexamethasone(Dex),HEL low dose 6 g/kg(HEL-L),HEL medium dose 18 g/kg(HEL-M)and HEL high dose 54 g/kg(HEL-H)*** model rats were intratracheally injected with 3 mg/kg LPS to establish an ALI *** counts,lung wet/dry weight ratio,as well as myeloperoxidase(MPO)activity were determined followed by the detection with hematoxylin and eosin staining,enzyme linked immunosorbent assay,quantitative real time polymerase chain reaction,western blotting,immunohistochemistry,and ***,to explore the effect of HEL on ALI-mediated intestinal flora,we performed 16s rRnA sequencing analysis of intestinal ***:HEL attenuated LPS-induced inflammation in lung tissue and intestinal flora *** study indicated that HEL suppressed the lung coefficient and wet/dry weight ratio of LPS-induced ALI in rats,inhibited leukocytes exudation and MPO activity,and improved the pathological injury of lung *** addition,HEL reduced the expression of tumor necrosis factoralpha,interleukin-1beta(IL-1β)and interleukin-6(IL-6)in bronchoalveolar lavage fluid and serum,and inhibited nuclear displacement of nuclear factor kappa-B p65(nF-κBp65).And 18 g/kg HEL also reduced the expression levels of toll-like receptor 4(TLR4),myeloid differentiation factor 88,nF-κBp65,phosphorylated inhibitor kappa B alpha(phospho-IκBα),nod-like receptor family pyrin domain-containing 3 protein(nLRP3),IL-1β,and interleukin-18(IL-18)in lung tissue,and regulated intestinal flora disturban

关键词： Yemazhui(Herba Eupatorii Lindleyani) acute lung injury anti-inflammation toll-like receptor 4 nuclear factor kappa-B nod-like receptor family pyrin domain-containing 3 protein signal transduction gastrointestinal microbiome

Modelling analysis embodies drastic transition among global potential natural vegetations in face of changing climate

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Forest Ecosystems 2024年第2期11卷 184-192页

作者： Zhengchao ren Lei Liu Fang Yin Xiaoni Liu School of Earth Science and Resources Chang’an UniversityXi’an710054China Research Center of Ecological Construction and Environmental Conservation in Gansu Province Gansu Agricultural UniversityLanzhou730070China State Key Laboratory of Tibetan Plateau Earth System Environment and Resources(TPESER)Institute of Tibetan Plateau ResearchChinese Academy of SciencesBeijing100101China School of Land Engineering Chang’an UniversityXi’an710054China College of Pratacultural Science Gansu Agricultural UniversityLanzhou730070China

Potential natural vegetation(PnV)is a valuable reference for ecosystem renovation and has garnered increasing attention ***,there is limited knowledge on the spatio-temporal distributions,transitional processes,and underlying mechanisms of global natural vegetation,particularly in the case of ongoing climate *** this study,we visualize the spatio-temporal pattern and inter-transition procedure of global PnV,analyse the shifting distances and directions of global PnV under the influence of climatic disturbance,and explore the mechanisms of global PnV in response to temperature and precipitation *** achieve this,we utilize meteorological data,mainly temperature and precipitation,from six phases:the Last Inter-Glacial(LIG),the Last Glacial Maximum(LGM),the Mid Holocene(MH),the Present Day(PD),2030(20212040)and 2090(2081–2100),and employ a widely-accepted comprehensive and sequential classification sy–stem(CSCS)for global PnV *** find that the spatial patterns of five PnV groups(forest,shrubland,savanna,grassland and tundra)generally align with their respective ecotopes,although their distributions have shifted due to fluctuating temperature and ***,we observe an unexpected transition between tundra and savanna despite their geographical *** shifts in distance and direction of five PnV groups are mainly driven by temperature and precipitation,although there is heterogeneity among these shifts for each ***,the heterogeneity observed among different global PnV groups suggests that they may possess varying capacities to adjust to and withstand the impacts of changing *** spatio-temporal distributions,mutual transitions and shift tendencies of global PnV and its underlying mechanism in face of changing climate,as revealed in this study,can significantly contribute to the development of strategies for mitigating warming and promoting re-vegetation in degraded regions worldwide.

关键词： Potential natural vegetation Global warming Vegetation classification Predicted model CSCS

A Practical Approach for Missing Wireless Sensor networks Data Recovery

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China Communications 2024年第5期21卷 202-217页

作者： Song Xiaoxiang Guo Yan Li ning ren Bing The College of Communications Engineering Army Engineering University of PLANanjing 210007China The 63891 Unit of PLA Luoyang 471000China

In wireless sensor networks(WSns),the performance of related applications is highly dependent on the quality of data ***,missing data is almost inevitable in the process of data acquisition and *** methods often rely on prior information such as low-rank characteristics or spatiotemporal correlation when recovering missing WSns ***,in realistic application scenarios,it is very difficult to obtain these prior information from incomplete data ***,we aim to recover the missing WSns data effectively while getting rid of the perplexity of prior *** designing the corresponding measurement matrix that can capture the position of missing data and sparse representation matrix,a compressive sensing(CS)based missing data recovery model is ***,we design a comparison standard to select the best sparse representation basis and introduce average cross-correlation to examine the rationality of the established ***,an improved fast matching pursuit algorithm is proposed to solve the *** results show that the proposed method can effectively recover the missing WSns data.

关键词： average cross correlation matching pursuit missing data wireless sensor networks

Secure state estimation for cyber-physical systems with unknown input sliding mode observer

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Control Theory and Technology 2024年第2期22卷 244-253页

作者： Panpan Zhang Yuwei ren Yixian Fang Ang Liu School of Information Science and Engineering Shandong Normal UniversityJinan250358ShandongChina School of Information Engineering Shandong Management UniversityJinan250357ShandongChina

In recent years, cyber attacks have posed great challenges to the development of cyber-physical systems. It is of great significance to study secure state estimation methods to ensure the safe and stable operation of the system. This paper proposes a secure state estimation for multi-input and multi-output continuous-time linear cyber-physical systems with sparse actuator and sensor attacks. First, for sparse sensor attacks, we propose an adaptive switching mechanism to mitigate the impact of sparse sensor attacks by filtering out their attack modes. Second, an unknown input sliding mode observer is designed to not only observe the system states, sensor attack signals, and measurement noise present in the system but also counteract the effects of sparse actuator attacks through an unknown input matrix. Finally, for the design of an unknown input sliding mode state observer, the feasibility of the observing system is demonstrated by means of Lyapunov functions. Additionally, simulation experiments are conducted to show the effectiveness of this method.

关键词： Sparse attacks Cyber-physical systems Unknown input sliding mode Secure state estimation Adaptive switching mechanism

Effect of particle composition and consolidation degree on the wave-induced liquefaction of soil beds

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Acta Oceanologica Sinica 2024年第2期43卷 11-22页

作者： Zhiyuan Chen Yupeng ren Guohui Xu Meng Li Shandong Provincial Key Laboratory of Marine Environment and Geological Engineering Ocean University of ChinaQingdao 266100China Marine Ecological Restoration and Smart Ocean Engineering Research Center of Hebei Province Qinhuangdao 066000China Key Laboratory of Marine Environment and Ecology(Ocean University of China) Ministry of EducationQingdao 266100China Key Laboratory of Submarine Geoscience and Prospecting Techniques(Ocean University of China) Ministry of EducationQingdao 266100China

The wave-induced liquefaction of seabed is responsible for causing damage to marine *** composition and consolidation degree are the key factors affecting the pore water pressure response and liquefaction behavior of the seabed under wave *** present study conducted wave flume experiments on silt and silty fine sand beds with varying particle ***,a comprehensive analysis of the differences and underlying reasons for liquefaction behavior in two different types of soil was conducted from both macroscopic and microscopic *** experimental results indicate that the silt bed necessitates a lower wave load intensity to attain the liquefaction state in comparison to the silty fine sand ***,the duration and development depth of liquefaction are greater in the silt *** dissimilarity in liquefaction behavior between the two types of soil can be attributed to the variation in their permeability and plastic deformation *** permeability coefficient and compression modulus of silt are lower than those of silty fine ***,silt is more prone to the accumulation of pore pressure and subsequent liquefaction under external *** research has demonstrated that silt beds with varying consolidation degrees exhibit distinct initial failure ***,a dense bed undergoes shear failure,whereas a loose bed experiences initial liquefaction *** study utilized discrete element simulation to examine the microscopic mechanisms that underlie this phenomenon.

关键词： wave flume liquefaction pore water pressure consolidation permeability experiment discrete element simulation

Quasi-shadowing for Z^(d)-actions

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Acta Mathematica Sinica,English Series 2024年第6期40卷 1563-1580页

作者： Juan PAn Xian Kun ren Yun Hua ZHOU School of Mathematics and Statistics Chongqing Technology and Business UniversityChongqing 400067P.R.China College of Mathematics and Statistics Chongqing UniversityChongqing 401331P.R.China

A diffeomorphism is non-uniformly partially hyperbolic if it preserves an ergodic measure with at least one zero Lyapunov *** prove that a C^(1)-smooth Z^(d)-action has the quasishadowing property if one of the genera... 详细信息

关键词： Quasi-shadowing Z^(d)-action non-uniformly partially hyperbolic ergodic measure

Skull and vertebral bone marrow in central nervous system inflammation

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Fundamental Research 2024年第2期4卷 246-250页

作者： Honglei ren Qiang Liu Department of neurology Tianjin Neurological InstituteTianjin Institute of ImmunologyState Key Laboratory of Experimental HematologyInternational Joint Laboratory of Ocular DiseasesMinistry of EducationHaihe Laboratory of Cell EcosystemTianjin Medical University General HospitalTianjin 300052China

Emerging evidence has highlighted the capacity of hematogenous cells in skull and vertebral bone marrow to enter the meningeal borders via ossified vascular channels and maintain immune homeostasis in the central nervous system(CnS).CnS-adjacent skull and vertebral bone marrow comprises hematopoietic niches that can sense CnS injury and supply specialized immune cells to fine-tune inflammatory ***,we review recent advances in our understanding of skull and vertebral bone marrow-derived immune cells in homeostasis and inflammatory CnS ***,we discuss the implications for future development of therapies to mitigate CnS inflammation and its detrimental sequelae in neurological disorders.

关键词： Central nervous system Bone marrow Hematopoiesis Immune cells neuroinflammation Stroke Multiple sclerosis

Molecular Mechanism of Rice necrotic Lesion for Optimized Yield and Disease Resistance

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Rice science 2024年第3期31卷 285-299页

作者： HOU Xinyue WAnG Yuping QIAn Qian ren Deyong State Key Laboratory of Rice Biology and Breeding China National Rice Research InstituteHangzhou 310006China State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China Rice Research InstituteSichuan Agricultural UniversityChengdu 611130China

How to balance rice resistance and yield is an important issue in rice *** with mutated necrotic lesion genes often have persistent broad-spectrum resistance,but this broad-spectrum resistance usually comes at the expense of ***,many necrotic lesion mutants in rice have been identified,and these genes are involved in disease resistance *** review provides a detailed introduction to the characteristics,classification,and molecular mechanisms of necrotic lesion ***,we review the molecular regulatory pathways of genes involved in rice disease ***,we summarize the relationship between resistance and yield in rice using newly developed gene editing *** discuss a rational and precise breeding strategy to better utilize molecular design technology for breeding disease-resistant and high-yield rice varieties.

关键词： rice necrotic lesion regulation mechanism high yield high resistance