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The effects of 90-day feeding of D-psicose syrup in male wistar rats

Open Journal of Preventive Medicine 2011年第2期1卷 66-71页

作者： Tatsuhiro Matsuo reika ishii Yoko Shirai Faculty of Agriculture Kagawa University Ikenobe Miki-cho Kita-gun Kagawa 761-0795 Japan

D-Psicose is a rare sugar present in small quantities in natural products. In a previous study, we showed that D-psicose suppresses increase in plasma glucose and reduces body fat accumulation in rats. Based on acute and chronic toxicity testing in rats, D-psicose is classified as an ordinary and safe substance. Recently, we developed a high D-psicose syrup (PS) made from high fructose corn syrup (HFCS) by the alkaline isomerization method. However, the safety of PS as a food additive has not been demonstrated. In this study, we investigated the effects of 90-day feeding of PS in male Wistar rats. The rats were fed diets containing 3% D-psicose (control) or 4.3% PS for 90 days. The body weight gain and intra-abdominal adipose tissue weight did not differ between the control and PS group. The weights of the tissues did not differ between the two dietary groups. In clinical chemistry and hematological analyses, no differences were found between the control and PS groups. No gross pathological findings were evident at dietary doses of 4.3% PS. Therefore, the present study found no adverse effects of PS in rats fed a diet containing 4.3% PS for 90 days.

关键词： D-Psicose D-Psicose Syrup 90-Day Feeding Pathological Tests Rat

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高考日语黄宝书

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2019年

作者：许小明，reika

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新日本语能力考试N1备考攻略

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作者：许小明 reika

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新日本语能力考试N2备考攻略

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作者：许小明 reika

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高考日语10年真题与解析

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2019年

作者：许小明，reika

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Mechanical Performance Evaluation of Multi‑Point Clinch–Adhesive Joints of Aluminum Alloy A5052‑H34 and High‑Strength Steel JSC780

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Automotive Innovation 2023年第3期6卷 340-351页

作者： Yunwu Ma reika Akita Yohei Abe Peihao Geng Pengjun Luo Seiichiro Tsutsumi Ninshu Ma Shanghai Key Laboratory of Digital Manufacture for Thin‑Walled Structures School of Mechanical EngineeringShanghai Jiao Tong UniversityShanghai 200240People’s Republic of China Joining and Welding Research Institute Osaka UniversityOsaka 567‑0047Japan Itochu Techno-Solutions Corporation KamiyachoTokyo 105‑6950Japan Department of Mechanical Engineering Toyohashi University of TechnologyToyohashi 441‑8580Japan Graduate School of Engineering Osaka UniversityOsaka 567‑0047Japan

The clinch–adhesive process,which combines mechanical clinching and adhesive bonding,is one of the most applied pro-cesses for joining aluminum alloy and steel in the manufacturing of vehicle *** this hybrid process,the clinching joints and adhesive bonds are coupled and influenced by each other,posing challenges to the process design and joining strength *** understand the influence of the clinching process on the performance of the adhesive layer,this study analyzes the mechanical behavior of clinch–adhesive joints between high-strength steel JSC780 and aluminum alloy A5052-H34 with different stack-up orientations and varying numbers of clinching *** results reveal that,under the steel-on-top condition,the clinching process causes a discontinuous distribution of the adhesive layer,which significantly decreased the bonding *** contrast,under the aluminum-on-top condition,the clinching process has a lesser impact on the distribution of the adhesive layer,resulting in much higher strength than the steel-on-top *** mod-els are constructed to quantify the effect of clinching points on the performance of the adhesive *** results highlight the need to consider diverse cohesive zone model parameters for the different stack orientations and clinching points in the design of clinch–adhesive aluminum alloy/steel structures.

关键词： Adhesive bonding Clinching Dissimilar materials Stack orientation Cohesive zone model

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